Unusual Cases: Bridging Hematology and Flow Cytometry

Multiparameter flow cytometry has become an integral tool in the workup of abnormal WBC findings, allowing for rapid and accurate identification of abnormal cell populations, cell lineage assignment, and assessment of clonality. This presentation will discuss a series of cases that demonstrate the utility of flow cytometry in the diagnostic workup of hematologic disorders presenting with abnormal WBC differential and incorporation of relevant criteria from the revised WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues.
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OTHER ON-DEMAND WEBINARS

MHEALTH GOLDEN AGE MOBILE SECURITY IMPLICATIONS

Due largely to the global COVID-19 pandemic, we are now living in the golden era of mobile health, or “mHealth,” as it has come to be called. The World Health Organization defines mHealth.
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Validating Configurable Interactive Response Technology Solutions for Clinical Studies

Bioclinica

In this webinar, the validation of an interactive response technology (IRT) solution built with configurable parameters will be explored. Traditionally, interactive response technology solutions require validation of each study-specific requirement to ensure proper implementation. With the prevalence of configurable interactive response technology solutions where the validation of each configurable parameter occurs within the product, the need for full validation of each requirement within a clinical study has lessened. This webinar will explore how to take advantage of configurations and how to verify them, thereby reducing the effort and timeline required for validation while still maintaining quality within each study.
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Pharma R&D Review: What Changed In 2018, What To Look Out For In 2019

pharmaintelligence

The drug R&D pipeline in 2019, and how it is changing
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UNDERSTANDING THE PROPENSITY OF SEQUENCE VARIANTS DURING CELL LINE AND CULTURE PROCESS DEVELOPMENT

Bio Pharma Asia

Sequence variants (SVs) are protein isoforms that contain one or more unintended amino acid substitutions. They can arise at a single amino acid site due to a genetic (RNA/DNA) mutation or at multiple amino acid locations, potentially due to translational errors, also referred to as misincorporations. The ability to detect SVs in protein biotherapeutics is critical due to their potential impact on structural/functional characteristics, safety, and efficacy. Trypsin peptide mapping with liquid chromatography-ultrahigh resolution tandem mass spectrometry (LC-MS/MS) provides the ideal workflow for the detection, identification, and relative quantitation of both genetic and translational SVs.
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