CRISPR-created Animal Models: The Technical Lowdown

Creating reproducible animal models for long-term studies can often be problematic due to the complexity of the genetic modification(s) required. Suboptimal design strategies compound the challenges by generating undesired genotypic or phenotypic results. CRISPR-Cas9 or zinc-finger nuclease (ZFN)-based technologies can circumvent the challenges of complex genetic alterations due to the precision inherent to these methods. Beyond these methods, which result in constitutive changes to the genome, other genome editing methods are available; these include humanization, conditional knockout, point mutation, and reporter tagging. The sponsor of this webinar, Horizon Discovery, offers custom in vivo model generation services. Join us to learn how to go from concept to F1 in five months.