Excipients and Formulation Assessments of Complex Generic Products

Characterization of residual impurities for gene therapy drug products is particularly challenging due to the complex nature of the final products as well as the complicated processes required to manufacture them.

The management of the United States’ massive prescription drug spend is plagued by inefficient, manual processes and errors which exact enormous human and financial tolls on society.

Fibrotic diseases of the heart and liver impact a significant portion of the global population and are a growing public health concern. Fibrosis occurs when fibroblasts deposit excess extracellular material within the tissue in response to certain stimuli or injury. Myocardial fibrosis is associated with nearly all forms of heart disease. The pathological changes that can result from fibrosis include cardiomyocyte hypertrophy, chamber dilation, heart valve stiffening, and others, all of which contribute to heart failure. Nonalcoholic steatohepatitis (NASH) is a fatty liver disease characterized by hepatocyte inflammation that contributes to fibrosis, cirrhosis, and liver failure. NASH is closely linked to obesity and diabetes; changes in diet have thus contributed to its expansion and impact across the globe. Understanding the underlying biology of fibrosis is critical for the diagnosis, treatment, and management of cardiac fibrosis, NASH, and other fibrotic diseases.

This first of its kind online scientific conference brings the world of drug discovery and development to your desk or lab bench. You are free to choose the talks most relevant to your research to customize a conference experience that meets your needs. Cutting edge topics in the sessions will cover the use of the following as tools for drug discovery/development.