Streamlining “Library-to-Lead” for your Antibody Therapeutics

June 6, 2018

The number of therapeutic antibodies entering the market continues to grow annually, with 2017 seeing ten approvals in either the European Union or the United States supported by a robust late-stage clinical pipeline that will likely yield even more approved drugs in 2018 and 2019. Making a drug is an expensive and time-consuming endeavor requiring an incredible level of detail and rigor to ensure that drugs are safe, efficacious, manufacturable and convenient to administer to the patient. While antibody generation is highly commoditized, with modern in vivo and in vitro libraries typically producing vast numbers of clones, the analytical tools used to characterize them at the molecular level to understand their mechanism of action often fall orders of magnitude behind in throughput.

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Lifebit

At Lifebit, we're pushing forward the frontiers of health and knowledge by democratising access to omics data. We enable all researchers, whether novice or advanced, to run complex analyses and generate meaningful insights fast.

OTHER WHITEPAPERS
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Unlocking iPSCs to Improve CNS Modeling and Drug Discovery

whitePaper | June 15, 2022

To date, therapeutic advances in treating central nervous system (CNS) disorders have been incremental at best. As the global population increases and older demographics begin to make up a disproportionately larger percentage,

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Overcoming technical challenges in cell-based high throughput screens

whitePaper | November 11, 2022

Tremendous technological advancements in automated biotechnology and combinatorial chemistry have led to the widespread implementation of high throughput screening (HTS) for drug discovery since the early 1990s.

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Simulation in the pharmaceutical industry

whitePaper | November 24, 2022

The pharmaceutical industry will face many challenges over the next decade, from industry-wide trends to new operational pressures. The key to meeting these challenges is adopting an agile, scalable and efficient approach to drug discovery and manufacturing.

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The Never-Normal Future of Manufacturing

whitePaper | September 24, 2022

Let’s just say what we’re all thinking: 2020 was rough. It threw pretty much every element of our lives into disarray, and we suddenly had to become experts at navigating a new way of working, schooling and socializing.

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Choosing the Right Temperature Monitoring Solution

whitePaper | April 24, 2023

Globally, pharmaceutical regulators are becoming attuned to cold chain issues as biologics, vaccines, and other temperature‐sensitive products are commercialized for a global clientele. Many regulators now recommend including temperature monitoring technology in every cold chain shipment.

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DEVELOPING AND OPTIMIZING CLEANING PROCESSES

whitePaper | November 1, 2022

Equipment cleaning in manufacturing companies is often not given the same emphasis as other processes. It can be viewed as a task.

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Spotlight

Lifebit

At Lifebit, we're pushing forward the frontiers of health and knowledge by democratising access to omics data. We enable all researchers, whether novice or advanced, to run complex analyses and generate meaningful insights fast.

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