Silicones for pharmaceutical applications –analytical capabilities at Solvias

Silicones are used in pharmaceutical applications as part of formulations, as well as during manufacturing and in packaging. The term ‘silicones’ encompasses a large number of compounds based on polydialkylsiloxanes. The most common are trimethylsilyl-terminated polydimethylsiloxanes. Dimethicones and simethicones are used as active ingredients and antifoaming agents in numerous anti-flatulent or anti-acid formulations. In pharmaceutical formulations, while considered active ingredients, their effect is usually caused by their physical properties, as polydimethylsiloxanes are not metabolized.

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Synthon

Synthon, with headquarters in Nijmegen, the Netherlands, is an international pharmaceutical company and a leader in the field of generic human medicines. The company started its biopharmaceutical franchise in 2007 and is building a promising portfolio of next generation medicines.

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Simcyp™ PBPK for Drug-Drug Interactions (DDI)

whitePaper | July 4, 2023

The past two decades have witnessed transformative changes in our approach to using modeling & simulation to assess and manage DDIs. Multidisciplinary innovations in mechanistic assessment of absorption, distribution, metabolism, and excretion (ADME), population pharmacology and pharmacogenetics.

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Optimizing the Path from Pre-Clinical to Clinical Development

whitePaper | December 22, 2022

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whitePaper | December 14, 2022

When the regulatory hammer came down on pharmaceutical and life sciences (PLS) companies in the 2010s, it introduced new complexities for these businesses.

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Shifting to an Audience-Focused Product Marketing Strategy

whitePaper | February 24, 2023

The WBR Insights research team surveyed 100 leaders from pharmaceutical companies to generate the results featured in this report. The respondents occupy roles in marketing, sales, commercial strategy, and product development.

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Non-Clinical Testing Considerations: Drugs vs Devices

whitePaper | November 8, 2022

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Navigating the Drug Development Pipeline: Expertise for Highly Potent API Product Handling

whitePaper | July 11, 2022

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Spotlight

Synthon

Synthon, with headquarters in Nijmegen, the Netherlands, is an international pharmaceutical company and a leader in the field of generic human medicines. The company started its biopharmaceutical franchise in 2007 and is building a promising portfolio of next generation medicines.

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