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GABAA Receptors Application Note

January 11, 2019

GABAA receptors represent a large and complex family of ion channels that consist of at least 16 subunits (α1-6, β1-3, γ1-3, δ, ε, π, θ) and have been shown to be vital for the normal functioning of the brain. These ligand-gated chloride ion channels form pentameric structures and are activated by γ-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the CNS, resulting in an inhibitory effect on neurotransmission

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GABAA Receptors Application Note