Efficient Removal of Aggregates from Monoclonal Antibodies

December 26, 2018

Monoclonal antibody (mAb) therapeutics have been widely used to treat various diseases, including cancer. Oftentimes, dimers and other high molecular weight aggregates are present in the mAb therapeutics, leading to reduced biological activity. Traditionally-used methods for aggregate removal rely heavily on anion exchange chromatography (AEX) in flow-through mode followed by a generic bind/elute polishing step.

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PartsSource Inc.

PartsSource is the leading evidence-based B2B vertical marketplace and supply chain software platform used by healthcare provider and supplier ecosystem to improve essential clinical operations, staff productivity, costs and asset uptime.

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