Split protein biosensor assays in molecular pharmacological studies

Cellular signalling is commonly mediated through dynamic protein– protein interactions (PPIs). When pivotal PPIs are deregulated, cellular signalling can be altered; itis therefore attractive to monitor regulated PPIs to understand their role in health and disease. Genetically encoded biosensors that rely on protein fragment complementation have made it feasible to monitor PPIs in living cells precisely and robustly.

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Kent Pharmaceuticals

Kent Pharmaceuticals is one of the leading pharmaceutical companies in the UK with 29 years of expertise in supplying quality products and services to the primary and secondary care sectors. From generics, OTCs, own label, overlabelling or manufacturing, we tailor our offering to our customers.

OTHER WHITEPAPERS
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Unlocking iPSCs to Improve CNS Modeling and Drug Discovery

whitePaper | June 15, 2022

To date, therapeutic advances in treating central nervous system (CNS) disorders have been incremental at best. As the global population increases and older demographics begin to make up a disproportionately larger percentage,

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Advancements in Drug Development and Formulation

whitePaper | December 13, 2022

A recent e-symposium presented insights into the latest research and innovative solutions to help shorten timeto-market, reduce development costs, increase yield, and assure quality and pharmacopoeia compliance throughout the drug development process.

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Utilizing Multi-parameter Epitope Binning to Understand aTherapeutic Antibody’s Mechanism of Action

whitePaper | January 20, 2023

Understanding an antibody’s mechanism of action (MOA) is critical to its clinical success. Not only does MOA have a large impact on safety and efficacy.

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Application Notes & Whitepapers 2019

whitePaper | December 19, 2019

Welcome to European Pharmaceutical Review’s Application Notes & Whitepapers Supplement 2019. This year’s topics range from analytical techniques for bioprocess investigation, host cell protein analysis and Raman imaging to advice on outsourcing services for product characterisation.

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A Futuristic Approach to Message Testing for Pharma Companies

whitePaper | March 10, 2023

In the last decade, the pharma industry has gone through significant changes in how it messages to physicians, patients and payers. The processes and tools that pharma brands use to DEVELOP and DELIVER messages have been disrupted by new technologies.

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Pharma R&D Annual Review

whitePaper | March 15, 2022

Successes in 2021 – New active substance drug launches

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Spotlight

Kent Pharmaceuticals

Kent Pharmaceuticals is one of the leading pharmaceutical companies in the UK with 29 years of expertise in supplying quality products and services to the primary and secondary care sectors. From generics, OTCs, own label, overlabelling or manufacturing, we tailor our offering to our customers.

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