Sosei Heptares to get $3m Pfizer milestone payment

pharmatimes | June 10, 2019

Sosei Heptares to get $3m Pfizer milestone payment
Sosei Heptares has announced that it is to receive a new $3 million milestone payment from its strategic alliance partner Pfizer, as it advances a second candidate from the GPCR collaboration for clinical development. The first clinical candidate under this collaboration was nominated by Pfizer in May 2019, after the deal was initially signed in November 2015 to research and develop potential new medicines directed at up to ten GPCR targets across multiple therapeutic areas. Many of these targets have clinical or biological validation as key points for therapeutic intervention potentially targeting a range of diseases but have proven difficult to address with conventional discovery approaches because of inherent technical challenges. Because of these challenges, Sosei and Pfizer scientists worked closely together to leverage their joint expertise in enabling GPCR-focused structure-based drug design (SBDD) and development initially directed to the GPCR targets selected by Pfizer. Under the agreement Pfizer will be responsible for developing and commercialising any potential therapeutic agents (small molecules or biologics) for each target and will have exclusive global rights to any potential resulting agents. Sosei are “Very pleased to reach this development milestone for another candidate in our partnership with Pfizer so soon after nominating the first clinical candidate last month,” according to Dr Malcolm Weir, executive VP and chief R&D officer.

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Thousands of scientists were sent home on temporary non-paid leave, what does it mean for the research they had to leave behind? “A shutdown has these cascading effects on the scientific work of the organization,” said Daniel M. Ashe, a former director of the Fish and Wildlife Service. “They’re hard to foresee or predict right now, but they’re crippling, really, and they affect the organization not for three or four weeks, but for the rest of the year because of all of this complex orchestration of field work.”


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RESEARCH

Hemogenyx Pharmaceuticals and Selexis SA Will Advance Hemogenyx’s Acute Myeloid Leukemia (AML) CDX Bispecific Antibody to Human Trials

Hemogenyx Pharmaceuticals plc | January 13, 2022

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BUSINESS INSIGHTS

Omnicell Completes Acquisition of ReCept

Omnicell, Inc. | December 30, 2021

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BUSINESS INSIGHTS

Deargen Annonuces Patent Application for a TNBC Target Novel Drug Candidate Using AI

Deargen Inc. | December 23, 2021

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BUSINESS INSIGHTS

SiO2 Materials Science and Doosan Corporation Enter Into Strategic Partnership to Accelerate Market Development in Asia

SiO2 Materials Science | December 27, 2021

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Spotlight

Thousands of scientists were sent home on temporary non-paid leave, what does it mean for the research they had to leave behind? “A shutdown has these cascading effects on the scientific work of the organization,” said Daniel M. Ashe, a former director of the Fish and Wildlife Service. “They’re hard to foresee or predict right now, but they’re crippling, really, and they affect the organization not for three or four weeks, but for the rest of the year because of all of this complex orchestration of field work.”

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