Six factors associated with invasive breast cancer recurrence after DCIS diagnosis
Current guidelines recommend surgical excision of DCIS, often followed by radiotherapy and sometimes endocrine therapy, yet most cases will likely not progress or become life-threatening. As a result, many women are overtreated. "There is a large unmet need to distinguish harmless from potentially hazardous DCIS," said senior author of the study Wesseling. "We hope our work will help reduce the burden of intensive treatment that thousands of women with low-risk DCIS undergo annually."