Embracing and investing in new technologies is one way to get ahead, and adopting lean, efficient manufacturing procedures is another. At a fundamental level, achieving efficiency can start at the outset of a project by considering the very design of a production facility. Careful planning can cut costs and reduce waste at all stages, while at the same time ensuring the production of quality products. For both new entrants wishing to establish a position in the sector, and for established OSD producers seeking to successfully expand their product ranges, getting the end product consistently right is, of course, crucial. In this article, we take a look beyond the processes involved in drug manufacture itself, and instead turn our attention to an often overlooked and underappreciated factor of the manufacturing process: that of materials handling.