Biotechne
Western blotting uses antibodies to identify individual proteins within a cell or tissue lysate. It is an important life sciences technique that involves many steps. When done well Western blotting delivers useful information to the researcher. Good results can, at times, be challenging. Sourcing quality reagents and finding ways to avoid repeating experiments is essential. This webinar offers insights into the tips and tricks that can help you generate better Western blot data and will discuss advances that have allowed the automation of protein separation and immunodetection of traditional Western blotting.
Watch Now
chromatographyonline
Sample preparation is an essential step for analytical chromatography, and recently biopharmaceutical analysts are discovering the need for cleaner, concentrated and targeted sample preparation methods for large molecules. This webcast will introduce how to properly clean up and isolate monoclonal antibodies (mAbs) using a high capacity paramagnetic bead solution, demonstrate how to optimize clean-up of excess labeling reagent, salts, or surfactants before N-glycans analysis, and how to utilize a multi-mode polymeric SPE for concentrating, solvent switching and sensitivity of samples.
Watch Now
Charles River
Therapeutic approaches for Parkinson’s disease are either focused on disease modification (a-synuclein or MPTP models) or symptom management (haloperidol or 6-OHDA models). Therapeutic approaches for Parkinson’s disease are either focused on disease modification (a-synuclein or MPTP models) or symptom management (haloperidol or 6-OHDA models). Our scientists have validated available PD models for changes in fine motor skills, L-dopa-induced dyskinesias, drug-induced jaw movements, and non-motor endpoints such as cognition, constipation, and EDS. Additionally, we have also tested dopamine and other neurotransmitter levels in brain compartments of rodent and large animal models via microdialysis sampling.
Watch Now
BioPharma Asia Magazine
Manufacturing has been paid dividends for many years through the use of quality tools such as statistical process control, quality function deployment, vendor audit management, hazard analysis critical control points (HACCP), value stream analysis, and other valuation methods. In the highly regulated industries that manufacture pharmaceuticals, foods, and cosmetics, the quality control ‘scientists’ have been typically known to perform sampling and testing for determining the acceptability of finished products. During the past decade, the pharmaceutical industry has seen a significant regulator-industry aligned paradigm change and an important leap into the formality of quality improvement using quality tools. The paradigm of final product testing (and the myth of ‘testing quality into products’) has been challenged by both the industry and regulators. Recent industry and regulatory support of ‘risk-based’ concepts and principles are intended to produce a ‘desired state’ of industry development and production of pharmaceuticals that have a higher level of consistency in meeting purity, safety, and efficacy than in prior history.
Watch Now