Antibody Drug Conjugates (ADCs) have a highly specific mechanism of action which is an advantage for the treatment of several oncology indications. They are made of a highly toxic payload, a linker, and an antibody.
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sigmaaldrich
Microbial risk in pharmaceutical process is not limited to living microorganisms and intact microbial cells. Subcellular components from microorganisms remaining from the production process can be source of pyrogens, compromising product quality and patient safety as these substances are not eliminated by classical filtration or sterilization steps.
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The focus on accelerated development of new modalities for advanced therapies and challenges with complex drug candidates has driven the adoption of novel concepts and technologies in pharmaceutical development and manufacturing.
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on24.com
With the continued pressure to reduce costs through innovations and efficiencies all while delivering faster sample results, the use of an On-line Water Bioburden Analyzer (OWBA) is one way companies can meet these demands. OWBA technology has the flexibility to be used for purified water, water for injections or even cleaning verifications and provides real time microbial detection as an early warning for system health. The benefits for using an OWBA include the potential for energy savings through reduced loop sanitation, labor cost reduction and improved product quality and process understanding.
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