Phenotypic Screening in Drug Discovery

In the past few years, there has been a revival of phenotypic screening for hit discovery and profiling. It is generally accepted that overexpression of targets in heterologous systems has a risk of creating functional artefacts, and in principle, such an assay is single-target focused.
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Spotlight

OTHER ON-DEMAND WEBINARS

See the Impossible: Navigating Pharma Procurement in a Complicated World

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M&IW’s HMCC-certified buyers recently attended Pharma Forum and picked up the latest and greatest tips on sourcing healthcare meetings. In our next See the Impossible Webinar Series, learn how transparency, accountability and creative thinking can alleviate unnecessary back and forth and streamline the hotel procurement process.
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Pichia for Bio-Pharmaceutical Manfuacturing

There has been growing interest in Pichia for use in the production of biopharmaceuticals including: SARS CoV2 spike protein and RBD, antibodies and other proteins for medicinal purposes.
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MAT: a powerful tool to assess pyrogenic risk in pharmaceutical process

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Microbial risk in pharmaceutical process is not limited to living microorganisms and intact microbial cells. Subcellular components from microorganisms remaining from the production process can be source of pyrogens, compromising product quality and patient safety as these substances are not eliminated by classical filtration or sterilization steps.
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The digital lab of the 21st century

Life science companies face major obstacles to continue operations and profitability. Examples include patent expirations, low research and development productivity, increased competition, decreased margins, non-optimized processes and mounting compliance pressure.
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