Pharmaceutical quality control: Connecting with your supply chain!

When it comes to the Pharma supply chain, problems can occur at any part of the process, including non-standardized bills of material, translation mistakes, typos and poor proofreading, missed annotations, unclear briefs, artwork problems, expired digital assets, third-party artwork suppliers and printing shops. Consumer and pharma companies must also deal with a very strict regulatory environment. Each time there is a problem, the manufacturer risks having to issue a (potentially major) recall.
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Pharma Trend Outlook 2022

As we approach the end of a year which saw global vaccine rollout for COVID-19, 44 novel drug approvals (to date) and the return of the CPHI Worldwide in-person event, we’re looking ahead to what 2022 has in store for the pharma industry.
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Practical Applications in Clinical and Real-World Research

The ability to link disparate datasets with de-identified or anonymized patient data has existed for decades but has been unrealistic to apply at scale.
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Nitrosamine Impurities in Rifampin – What Does it Mean for Your Drug-Drug Interaction (DDI) Study?

N-Nitrosamine impurity findings in marketed formulations of rifampin have disrupted drug development. As a strong cytochrome P450 3A4 (CYP3A4) inducer, rifampin was regularly co-administered with investigational products
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How to get speed and depth in your Host Cell Protein (HCP) analysis

Technology Networks

In the rapidly expanding arena of biotherapeutic analysis and bioprocess development, the analysis of host cell proteins (HCP) is transitioning to a new phase. HCPs are contaminants in biotherapeutic drug preparations, often at low ppm concentration levels, and must be monitored due to stability, efficacy and immunogenicity concerns. Often, these protein impurities will be considered Critical Quality Attributes (CQA) and can contribute to an overall risk assessment for the product.
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