Managing Risk and Opportunity for Immediate- and Modified-Release Drug Formulations

Formulators modify the release profiles of drugs for multiple reasons: to target delivery of the API, enhance bioavailability, provide dosage convenience, improve patient adherence, and extend the patentable life cycle of an existing drug.Whether the desired profile is for immediate or modified release, formulators must overcome the development hurdles of poorly soluble APIs. Modified-release drugs may require more excipients and more complex formulations and manufacturing steps, resulting in longer, and more expensive, development processes. Proven formulation methods and careful excipient selection, however, can be employed to develop formulations for modified release drugs that offer value to the patient.
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OTHER ON-DEMAND WEBINARS

NEW TOOLS TO ASSESS THE RISK OF MICROBIAL IMPURITIES IN THE PHARMACEUTICAL MANUFACTURING PROCESS

Biopharma-asia

Large-scale Production of Biologics is susceptible to microbial contamination because many manufacturing steps occur under non-sterile conditions in aqueous systems at ambient temperature or 2-8 °C under substantially neutral pH conditions. Regardless of where in the Drug Substance (DS) manufacture (manufacture of the Active Pharmaceutical Ingredient), or Drug Product (DP) manufacture (manufacture of the Final Drug, e.g. formulated mAbs filled in vials or syringes) they occur, microbial contaminations can have a significant impact on product quality and patient safety.
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Improve ultrapure water system performance and uptime with ozone

europeanpharmaceuticalreview

This webinar is designed to help companies understand the application and benefit of ozone technology in ultrapure water systems and how ozone solutions can improve water system performance, uptime and product quality in pharmaceutical manufacturing applications.
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Improving Sterilising Filtration in the Biopharmaceutical Industry

business-review-webinars

Sterile filtration has been a cornerstone of bioprocessing for over 60 years and as the industry continues its change from stainless steel to single-use, filtration has also evolved, moving from cartridge to capsule format with several membrane types to choose from. This webinar aims to provide an overview of filtration in bioprocessing addressing key considerations when developing a biopharmaceutical manufacturing process.
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The Future of Real-World Evidence: Pharma’s Next Moves

Throughout the pharma industry, real-world evidence (RWE) is leveraged across organizations for key decision-making within a therapy’s life cycle — from R&D to new US Food and Drug Administration (FDA) drug submissions to commercial strategy operations.
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