Improving Sterilising Filtration in the Biopharmaceutical Industry

Explore the area of neuromodulation, which is seeing significant growth at a time when other medical device markets are facing declining growth. The team focus on three targeted neuromodulation areas, including: spinal cord stimulation (SCS), deep brain stimulation (DBS) and vagus nerve stimulation (VNS).

Enabling formulations becomes more and more necessary to obtain adequate exposure of APIs during (pre)-clinical research. Currently, most registered formulations to improve bioavailability are based on lipidic systems, which make use of intrinsic digestion processes within the GI tract, facilitating the absorption of APIs. Aside from a general absorption mechanism, lipidic systems can also promote lymphatic transport of poorly soluble drugs, such as hormones. In addition, many different indications, such as HIV therapy, oncology, immunosuppressant and even arising therapies related to medicinal cannabis (e.g. CBD) can benefit from lipid formulations. These formulations create multiple possibilities for oral administration because they can be manufactured as solutions, suspensions, emulsions, and self-(micro)emulsifying systems.

The COVID crisis has revealed the importance of rapid and optimized equipment design and scale up for drug and vaccine manufacturing processing as well as the necessity to maintain an optimal productivity level throughout the equipment lifecycle.

This webinar will review clinical and genetic risk factors for contralateral breast cancer in patients who have been newly diagnosed with breast cancer. A specific focus on the role of family history and genetic mutations on contralateral breast cancer risk will be outlined. The role of risk models and how to apply these and other prediction tools in the clinical setting will be reviewed.