How a Top-5 Pharma Doubled the Speed of Cell Line Development

Sexually transmitted infections (STIs) continue to affect most sexually active populations across the globe, especially the traditional high-risk groups for bacterial STIs such as young people, men who have sex with men (MSM) and individuals from black and minority ethnic populations. Bacterial STIs such as Gonorrhoea and Chlamydia remain common. In western settings, we have observed the re-emergence of high rates of syphilis and lymphogranuloma venereum, mostly in MSM. Urethral and vaginal discharge syndromes, genital ulcer disease are frequent clinical presentations. However, the development of highly sensitive molecular assays has revealed that asymptomatic infections are also common, particularly at extragenital sites, and probably drive transmission of STIs.

Compounds that are poorly soluble in water are still prevalent in the pharmaceutical industry drug development pipeline.

Vibrational Circular Dichroism (VCD) is used to determine the absolute configuration of compounds in solution. As a result, it doesn’t require crystalline substances.

Artificial intelligence (AI) holds the promise of transforming drug discovery. By harnessing large sets of chemical and biological data, AI can accurately predict the behavior and properties of small molecules.