Poorly soluble drugs for oral administration present unique formulation challenges, particularly during early development. Formulation in a lipid-based carrier can be a feasible approach, but usually requires extensive testing to find suitable excipient combination.
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Pharmtech
Delivery of therapeutics to the human eye is one of the most interesting—but challenging—endeavors a formulator can take on. The anatomy and chemical composition of the eye make it highly resistant to pharmaceutical penetration. Successfully circumventing these protective barriers requires intimate knowledge of ocular delivery as well as specialized development and manufacturing expertise.
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The COVID crisis has revealed the importance of rapid and optimized equipment design and scale up for drug and vaccine manufacturing processing as well as the necessity to maintain an optimal productivity level throughout the equipment lifecycle.
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Despite the efforts towards malaria eradication, the latest estimates show that the number of cases is rising and malaria continues to have a devastating impact on the most vulnerable populations.
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