Control-Alter-Delete: Epigenetic Regulation by Non-Coding RNAs in Neuronal Systems Webinar

Drug formulators should consider the physical properties of their products during pharmaceutical drug development. The physical properties of a solid drug substance are highly dependent on the solid form. It is critical to understand the solid form landscape and select the optimum solid form for drug performance, stability and manufacturability as early in the development process as possible. Join this free webinar to learn about different solid forms (polymorph and salt) and different technologies to achieve these forms

Biopharmaceutical companies are increasingly challenged to create a drug pricing strategy that both rewards value and innovation, and promotes affordability and access. During this webinar, PwC’s Health Research Institute will review findings from a new global survey of industry executives, and provide analysis and commentary on key drug pricing issues, including:

Serialization is a great achievement for our industry. However, most executives now realize that it is only part of the solution, and serialization alone cannot solve the escalating problems of counterfeiting and diversion within the pharmaceutical industry. The global value of pharmaceutical counterfeiting is $200B annually. More staggering is that the gray market is forecasted to reach almost $3 trillion by 2022.

Recently investigators have begun to harness new technology such as microfluidic modulation spectroscopy (MMS) to reveal protein structural changes, as a solid understanding of structure and function is extremely important to the effectiveness of biotherapeutic drugs and scientist today are challenged in gathering a complete understanding with current tools. During the biomanufacturing process, proteins such as antibodies, often undergo conformational changes that can alter their secondary structure, leading to critical variations in their overall function. These changes have been historically difficult to detect, as traditional analytical techniques are not great at detecting small differences in protein structure.