Artificial Intelligence in Drug Discovery

With Microsoft Azure DevOps, healthcare IT teams get a combination of processes, industry best practices and proven tools to make the most of their DevOps initiatives. The webinar discusses how organizations can leverage it to accelerate DevOps implementation.

Various ways to implement continuous manufacturing in pharmaceutical development and production

Scientists are always on the hunt for new analytical approaches that will streamline the biotherapeutic characterization process and answer questions found intractable using traditional methodologies. One such technique, hydrogen deuterium exchange mass spectrometry (HDX-MS)—a biophysical tool for characterizing protein conformation and dynamics—has become an indispensable method to answer important questions concerning therapeutic protein structure, stability, and interactions. Additionally, the correlation of HDX-MS profiles for a target protein interacting with a panel of ligands has facilitated the determination of structure-function relationships, and differentiated new ligand classes based on selective binding.

The clinical development marketplace continues to become more complex and competitive, with stricter regulatory standards and trial oversight—all the while demanding patient-centric drug development. These, and other factors, contribute to unsustainable costs and longer timelines before much-needed therapies reach the market.