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INTEGRATING POLYGENIC AND MONOGENIC GERMLINE TESTING RESULTS INTO PROSTATE CANCER RISK ASSESSMENT

SHARESHARESHARE
In this webinar, Dr. Xu will summarize recent data on inherited risk for prostate cancer, including germline mutations in high-penetrance genes (HPGs), risk-associated SNPs, and SNP-based genetic risk score (GRS). He will present detailed data supporting the broad-sense validity of GRS in risk assessment as well as the need for assessing the narrow-sense validity of GRS values. Finally, he will review the data supporting the importance of GRS when estimating the penetrance of HPGs.