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INHALATION DRUG DELIVERY: CONSIDERATIONS FOR TOXICOLOGY AND PHARMACOLOGY RESEARCH

SHARESHARESHARE
Drug delivery to the lungs in both the clinical and non-clinical setting is a unique combination of formulation, the delivery device and the system/model that the drug is being delivered to. Throughout different stages of drug development, the requirements for inhalation drug delivery change and the delivery system must change/evolve to meet the needs at each stage. Early proof-of-concept studies may make use of rodent species, simple formulations that minimize excipients, ‘off-the-shelf’ delivery devices and may utilize direct to the lungs as an option.