home.aspx

 
.

HME LIPIDIC PELLETS FOR PAEDIATRIC APPLICATION. AN INVESTIGATION OF THE EFFECT AND STABILITY ON DRUG DISSOLUTIONS

SHARESHARESHARE
Hot Melt Extrusion (HME) is an established processing technology that can be used for the development of paediatric formulations. The processing of lipids via HME has been proved ideal for high drug loaded dosage forms with sustained release of drugs. The study investigates the effect of the lipid type and the food grade on the dissolution rates of extruded pellets or extemporaneous formulations.