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Sanofi and Regeneron's Dupixent scores 3rd FDA approval in sinusitis with nasal polyps

June 26, 2019 / Eric Sagonowsky

Sanofi and Regeneron’s Dupixent has been charging ahead since its initial approval in moderate-to-severe atopic dermatitis, later picking up a follow-up nod in moderate-to-severe asthma. Wednesday, the drug scored FDA approval for its third use: to treat adults with chronic rhinosinusitis with nasal polyps. Dupixent is the first biologic medicine approved for the condition, which obstructs sinuses and nasal passages. The disease leads to difficulty breathing, reduction in sense of smell and taste and facial pressure. It’s also associated with diseases such as asthma.  In clinical testing, patients who took Dupixent experienced reductions in nasal polyp size and congestion and experienced improvements in their ability to smell. Patients on the med also required less surgery and steroids. Fifty-nine percent of study patients also had asthma, and those patients experienced better lung function, investigators found. About three-fourths of patients in testing “no long...