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Roche trumpets data for Soliris rival in NMOSD after US, EU filings

December 02, 2019 / Phil Taylor
SHARESHARESHARE

Roche has continued to build the case for satralizumab, its experimental therapy for rare disease neuromyelitis optica spectrum disorder (NMOSD), which is heading for approval decision in the US and Europe next year. The results of the pivotal SAkuraSky trial have now been published in the New England Journal of Medicine (NEJM) website, showing that the anti-interleukin-6 antibody cut the relapse rate in NMOSD compared to conventional immune-suppressing drugs over nearly three years of follow-up. NMOSD is an autoimmune disease of the central nervous system that primarily affects the optic nerves and spinal cord, causing blindness, muscle weakness and paralysis. Progression of the disease is characterised by unpredictable and severe relapses that lead to nerve damage, and it can often be misdiagnosed as multiple sclerosis. Roche is building the case for satralizumab as it approaches potential approvals of the drug and a market showdown with Alexion’s rare disease blockbuster Solir...