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New cannabis-based drug shows promise for pancreatic cancer

August 22, 2019 / Dr. Liji Thomas

Cancer of the pancreas is a particularly deadly cancer, claiming over 90 Precent of its victims within 5 years from diagnosis. It resists most standard therapies, including surgery, chemotherapy, radiation therapy, immunotherapy and targeted therapy, and metastasizes early, often before being diagnosed. A cure is possible only with very localized tumors. Now, however, a new cannabis-derivative called FBL-03G, loaded into tumor-targeted smart radiotherapy biomaterials systems (SRBs systems), shows great promise in killing cancer cells within a treated tumor as well as in other distant parts of the body, with a survival advantage. FBL-03G is a cannabis flavonoid, a synthetic derivative of Cannflavin B. It is not a cannabinoid, and lacks psychoactive properties. This new study uses SRB-loaded FBL-03G introduced into the tumor to test its ability to improve the tumor response to radiation therapy. This is called radiosensitization. It also seeks to explore the immunomodulatory properties o...