FDA says Clovis’ Rubraca could be prostate cancer breakthrough

Clovis Oncology’s Rubraca (rucaparib) has been designated as a Breakthrough Therapy by the FDA in prostate cancer, paving the way for a faster review if clinical trials work out. The FDA has said that phase 2 data suggest the drug could represent a new therapy option for men whose cancer has progressed despite chemotherapy, and treatment with androgen receptor therapy such as Pfizer/Astellas’ Xtandi (enzalutamide), or Johnson & Johnson’s Zytiga (abiraterone). Already approved in ovarian cancer, Boulder, Colorado-based Clovis is developing Rubraca as a potential therapy for prostate cancer.