Drug Development process

April 12, 2019

Drug discovery is an iterative process. It goes back and forth between theoretical biology; the necessary, appropriate, and humane use of animal assays to determine a compound’s biological activity in the body; and medicinal chemistry to optimize the compound. Then in human studies, clinical observations test hypotheses about how a candidate drug may target cancer cells; determine its safety and effective doses; and compare its ability to shrink tumors or stop cancer progression relative to standard therapy. The NIH generally helps fund all stages of research up through phase II clinical trials, as indicated by the red borders of some panels of the flowchart.

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Agios Pharmaceuticals

Agios is a biopharmaceutical company passionately committed to applying our scientific leadership in the field of cellular metabolism to transform the lives of patients with cancer and rare genetic disorders of metabolism, which are a subset of orphan genetic metabolic diseases.

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Spotlight

Agios Pharmaceuticals

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