New FDA report claims low prices contribute to drug shortages

Medical Economics | October 31, 2019

A report from the FDA’s Drug Shortages Task Force claims one of the root causes of drug shortages is the low price of older generic medications. The task force, which is made up of members several federal agencies, released the report October 29. It examined 163 different drugs which experienced shortages. The overall conclusion of the report is that, due to medications not following generally accepted rules of supply and demand, any time there is a quality issue with a drug the manufacturers have trouble replacing the flawed stock due to economic factors. The price of these older generic drugs was listed in the report as the first root cause of drug shortages which have led to 56 percent of hospitals reporting they had changed a patient’s treatment as a result of a shortage. Low prices, the report claims, limit a manufacturer’s profitability and makes them less motivated to stay in or enter the market for these older generic drugs and invest in manufacturing quality and redundancy. The report also identifies the lack of available information on which facilities produce drugs thus inhibiting the market from rewarding quality producers as another root cause. This leads manufacturers to limit their investment in manufacturing quality. The last root cause the report identifies is that after a supply disruption, sometimes caused by lax quality management, logistical and regulatory challenges make it difficult for the market to recover.

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ETC met with Keeley Rothwell the Retail Manager at Blooms the Chemist Elanora to get the inside scoop to help job seekers who are interested in a career in the Pharmacy industry.

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ETC met with Keeley Rothwell the Retail Manager at Blooms the Chemist Elanora to get the inside scoop to help job seekers who are interested in a career in the Pharmacy industry.

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NovaBay Pharmaceuticals Collaborates with Harrow Health’s ImprimisRx to Promote Prescription Avenova

NovaBay Pharmaceuticals | July 20, 2021

NovaBay Pharmaceuticals, Inc., a pharmaceutical firm focused on commercializing Avenova for the eye care market, has announced a collaboration with ImprimisRx, one of the nation's top ophthalmology-focused pharmaceutical companies, to promote prescription Avenova. ImprimisRx, a wholly-owned subsidiary of Harrow Health, Inc., will offer national sales, marketing, and distribution support for NovaBay's FDA-cleared 0.01% hypochlorous acid Avenova in 40 ml bottles. Avenova is a clinically approved antimicrobial lid and lash solution used to treat various chronic eye conditions. Avenova serves a large and rapidly growing dry eye market, with 30 million Americans suffering from chronic eye diseases such as blepharitis and meibomian gland dysfunction. It is the only lid and lash spray made with NovaBay's patented pure hypochlorous acid and is suitable for daily usage. In addition, Avenova is usually prescribed by ophthalmologists and optometrists before and after cataract and Lasik procedures, making it a complementary therapy for many ImprimisRx's existing products. About ImprimisRx ImprimisRx is one of the nation's top ophthalmology-focused pharmaceutical companies, with 40 proprietary ophthalmic formulations serving thousands of ophthalmologists and optometrists throughout all 50 states. About Harrow Health Harrow Health, Inc. is a healthcare company specializing in ophthalmology. ImprimisRx, the leading ophthalmology-focused pharmaceutical company, and Visionology, a direct-to-consumer eye care subsidiary focusing on chronic eye disease, are owned and operated by the company. Harrow Health also owns stakes in Eton Pharmaceuticals, Surface Ophthalmics, and Melt Pharmaceuticals, all of which began as Harrow Health subsidiaries. Harrow Health also has royalty rights to four clinical-stage drug candidates developed by Surface Ophthalmics and Melt Pharmaceuticals. About NovaBay Pharmaceuticals, Inc. NovaBay Pharmaceuticals, Inc. is a biopharmaceutical company focused on high-quality, differentiated anti-infective consumer products such as Avenova, the top antimicrobial lid and lash spray, CelleRx Clinical Reset, a game-changing product in the beauty category, and NeutroPhase Skin and Wound Cleanser for wound healing. NovaBay products include its patented, pure, stable, pharmaceutical-grade hypochlorous acid, replicating the antimicrobial chemicals used by white blood cells to combat infection. NovaBay's hypochlorous acid products cause no stinging or irritation, are nontoxic, and are non-sensitizing, making them entirely safe for daily usage. In addition, Avenova is the first commercial hypochlorous acid lid and lash spray product that has clinically proven to reduce bacterial load on ocular skin surfaces, effectively addressing the underlying cause of bacterial dry eye.

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Seagen and Sanofi Announced Partnership for the Development and Commercialization of Multiple Novel Antibody-Drug Conjugates

Seagen Inc. | March 17, 2022

Sanofi and Seagen signed an exclusive partnership agreement to discover, develop, and market antibody-drug conjugates targeting three cancer targets. Sanofi's patented monoclonal antibody technology and Seagen's proprietary ADC technology will be used. Sanofi presently has one ADC under development, an antibody designed to deliver strong anti-cancer medications to tumor cells expressing a particular protein. “We are excited to be working with Sanofi, a global biopharmaceutical leader, to identify new ways to address unmet medical needs of cancer patients potentially. Jointly developing novel ADCs by combining antibodies from Sanofi with Seagen’s proprietary ADC technology aligns with our strategic priorities to expand the global potential of our pipeline with new first- or best-in-class programs.” Clay Siegall, Ph.D., President, and Chief Executive Officer, Seagen According to John Reed, M.D., Ph.D., Global Head of Research and Development, Sanofi, “This collaboration will enable the synergistic combination of molecules and platforms to produce candidate medicines to bring renewed hope to cancer patients and their families. We look forward to joining forces with Seagen to collaboratively design and develop promising medicines by advancing antibody-drug conjugate science.” Seagen and Sanofi will co-fund worldwide development operations and split any future earnings equally under the terms of the agreement. In addition, once each of the three targets is chosen, Sanofi will provide an undisclosed payment to Seagen. The collaboration's first goal has already been established.

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Ginkgo Bioworks and Novo Nordisk to Collaborate on Expression Systems for Pharmaceutical Products

Ginkgo Bioworks and Novo Nordisk, | June 08, 2022

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