Indian-origin head of US pharmaceutical major found guilty of bribing doctors to prescribe opioids

thehansindia | May 03, 2019

A 76-year-old Indian-origin head of a US pharmaceutical major has become the first top executive of a drugmaker to be convicted of bribing doctors in America to prescribe addictive painkillers, fuelling a national opioid crisis which has claimed the lives of tens of thousands of people over two decades. John Nath Kapoor, the founder of Insys Therapeutics pharmaceutical company based in Arizona state's Chandler city, was found guilty of criminal conspiracy by a jury in Boston, Washington-based National Public Radio reported. Kapoor, a one-time billionaire, was convicted on Wednesday along with four other former executives of the company. They face up to 20 years in prison. Kapoor and his co-defendants were accused by the federal government of running a nationwide bribery scheme. India-born Kapoor founded Insys Therapeutics in 1990. Between 2012 and 2015, Insys allegedly paid doctors to prescribe its potent opioid medication and then lied to insurance companies to ensure that the expensive fentanyl-based painkiller would be covered, the report said.

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Working in strictly regulated environments, pharma and cosmetics companies need to ensure the quality and safety of their products.

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Working in strictly regulated environments, pharma and cosmetics companies need to ensure the quality and safety of their products.

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BUSINESS INSIGHTS, PHARMA TECH

EU Approves Zynlonta for Relapsed or Refractory Diffuse Large B-cell Lymphoma

ADC Therapeutics | January 03, 2023

Sobi® and ADC Therapeutics SA informed that Zynlonta® (loncastuximab tesirine) has recently received conditional marketing authorization from the European Commission (EC) for the treatment of diffuse large B-cell lymphoma ((DLBCL) that has relapsed or become resistant. The approval comes after the European Medicines Agency's Committee for Medicinal Products for Human Use issued a favorable opinion in September. Sobi has said that it wants to give Zynlonta, a new treatment for diffuse large B-cell lymphoma, to people in the European Union who have this debilitating blood cancer. The approval was granted based on the findings from LOTIS-2, which was a large (n=145), phase 2 multinational, single-arm clinical study of Zynlonta for treating adult patients who had relapsed or refractory DLBCL following two or more prior lines of systemic therapy. Zynlonta was granted accelerated approval by the United States Food and Drug Administration in April 2021. This approval made it the first CD19-targeted antibody-drug conjugate to be used as a single-agent treatment for adult patients who had relapsed or been resistant to two or more lines of systemic therapy for their DLBCL. Sobi announced an exclusive license agreement with ADC Therapeutics to develop and commercialize Zynlonta in Europe and other international markets. The license aims to boost Sobi's presence in hematology, one of its two main disease areas. Besides, Zynlonta will be sold with other Sobi hematology drugs. ADC Therapeutics added that this approval expands Zynlonta's global reach. Zynlonta will fill a critical unmet need for DLBCL patients in Europe. The EU decision applies to Iceland, Norway, and Liechtenstein. According to the terms of the license agreement and as previously communicated, Sobi will pay ADC Therapeutics USD 50 million as a result of the EU's approval of DLBCL. Sobi's clinical development and product supply are handled by ADC Therapeutics. About ADC Therapeutics ADC Therapeutics next-generation, targeted antibody-drug conjugates help cancer patients. With a deep understanding of oncology and an ADC platform that the FDA's approval of Zynlonta has proven, the company is working to meet unmet medical needs and improve outcomes for people with hard-to-treat hematological cancers and solid tumors. ADC Therapeutics' highly skilled global team is committed to fighting cancer with science, bringing targeted therapies and hope to patients and their families.

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BUSINESS INSIGHTS, PHARMA TECH

Arrowhead Pharmaceuticals Announces $25 Million Milestone Payment from Amgen

Arrowhead and Amgen | December 21, 2022

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BUSINESS INSIGHTS, PHARMA TECH

USP Introduces Analytical R&D to Optimize Continuous Manufacturing Technologies

US Pharmacopeia | January 04, 2023

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