TrialCard | August 31, 2021
TrialCard Incorporated today announced the launch of Engage HCP by TrialCard, a new expanded suite of services that serves as a complement to a biopharma brand's field teams, while delivering measurable results in brand reach, lead generation, and market share growth.
Engage HCP by TrialCard is designed to offer a flexible array of services that can serve as standalone teams or be used to bolster the efforts of existing field teams. Engage HCP offers HCP engagement services for the following disciplines:
Clinical Nurse Educators
Field Reimbursement Managers
Pharmaceutical Institutional, Sales, and Specialty Representatives
Rare Disease Professionals
Medical Science Liaisons
These augmented services strengthen TrialCard's original position in virtual detailing, which began several years ago.
"TrialCard developed this suite of services to address for our clients the increasing number of "difficult to see" and "no see" HCPs," said Tom Heck, SVP of Commercial Solutions at TrialCard. "Engage HCP by TrialCard further solidifies our commitment to helping brands grow and thrive via non-traditional methods."
Long before the COVID-19 global pandemic altered the traditional pharmaceutical selling cycle, pharma sales reps' access to HCPs had been decreasing for years. According to ZS's 2019 AffinityMonitor findings, only 47.3% of physicians engaged well with in-person pharma rep meetings, while just 9.6% of physicians engaged using digital tactics. TrialCard, a pioneer in digital HCP engagement, recognized this opportunity and began reaching out to physicians via digital channels years ago.
"Many predict that it is unlikely society will ever return to pre-COVID-19 behavior," said Mark Bouck, President and CEO of TrialCard. "As HCPs become more accustomed and comfortable with digital communications, they will likely continue to become even less reliant on face-to-face interaction."
"Our pharmaceutical sales reps enter the physician's office using technology instead of the front door," said Mike Davis, TrialCard's VP of Commercial Solutions. "While that technology is the backbone of our programs, our proven track record in supplementing a brand's field sales force is a result of the caliber of talent that we hire, the superior training and resources we provide, and the flexibility, experience, and expertise to create customized solutions for each client."
TrialCard Incorporated is a full-service life sciences commercialization partner that provides comprehensive solutions that span the entire biopharmaceutical value chain. In addition to a foundation of fully integrated, digitally enabled patient support services, its broader offerings include everything from late-stage clinical trial management to post-marketing HCP engagement services and proprietary data-as-a-service payer intelligence and insights. Founded in 2000, TrialCard provides commercialization needs for more than 160 life science customers and has connected over 35 million patients with more than $18 billion in branded drug savings to date. The company is headquartered in Morrisville, North Carolina.
Insilico Medicine | January 18, 2022
Shanghai Fosun Pharmaceutical Co., Ltd, a leading innovation-driven international healthcare group in China and Insilico Medicine, an end-to-end artificial intelligence (AI)-driven drug discovery and development company, entered into a collaboration agreement to advance the discovery and development of drugs targeting a number of different targets globally through the use of AI technology.
This strategic collaboration includes an AI-driven drug discovery research and development (R&D) collaboration on four biological targets, as well as the co-development of Insilico's QPCTL program. Insilico will receive a total upfront payment of $13 million for the R&D collaboration projects and the co-development of the QPCTL program, potential milestone-based payments, and share commercialization profits from the QPCTL program. In addition, Fosun Pharma will make an equity investment in Insilico.
"We are pleased to enter into strategic collaboration with Insilico. Fosun Pharma is committed to promoting innovative R&D, and is oriented towards fulfilling unmet clinical needs and improving products' accessibility. We look forward to working with Insilico to leverage the technological and clinical development strengths of both companies, jointly improving the efficiency of innovative drug R&D, and benefiting more patients worldwide,"
Yifang Wu, Chairman and CEO of Fosun Pharma
The collaboration aims to combine Insilico's end-to-end AI-driven drug discovery platforms and Fosun Pharma's clinical development and commercial expertise to discover and develop a portfolio of novel therapeutics. Pursuant to the collaboration agreement, Insilico will take responsibility for delivering a preclinical candidate for the QPCTL program and advancing it to IND stage, after which, Fosun Pharma will then conduct human clinical studies and co-develop the candidate globally. In parallel, Fosun Pharma's R&D team will nominate four therapeutic targets to be assessed by Insilico's AI platform and R&D team, who are responsible of advancing drug candidates to IND stage.
As part of the collaboration, Fosun Pharma will secure access to Insilico's PandaOmics and Chemistry42 platforms in order to advance Fosun Pharma's internal AI-powered discovery and development efforts.
"In partnering with Fosun Pharma, a leading pharmaceutical company, we begin a new era of AI-powered end-to-end drug discovery and development as human-machine collaboration becoming the new normal in precision drug discovery and development. We previously demonstrated that AI can be used to discover novel targets and generate novel molecules that can be tested in humans in record time. Now, we are partnering with one of the leading scientific teams in the pharmaceutical industry to take this technology to the next level for the benefit of patients worldwide", said Alex Zhavoronkov, PhD, Founder and CEO of Insilico Medicine.
About Fosun Pharma
Founded in 1994, Shanghai Fosun Pharmaceutical Co., Ltd. is a leading innovation-driven international healthcare group in China. Fosun Pharma strategically operates businesses in the pharmaceutical and health industry, including pharmaceutical manufacturing, medical devices and medical diagnosis, and healthcare services. Through equity participation in Sinopharm Co., Ltd., Fosun Pharma's business extends to pharmaceutical distribution and retail.
About Insilico Medicine
Insilico Medicine, an end-to-end AI-driven drug discovery and development company, is connecting biology, chemistry, and clinical trials analysis using next-generation AI systems. Insilico Medicine has developed AI platforms that utilize deep generative models, reinforcement learning, transformers, and other modern machine learning techniques to discover novel targets and to design novel molecular structures with desired properties. Insilico Medicine is delivering breakthrough solutions to discover and develop innovative drugs for cancer, fibrosis, immunity, central nervous system diseases and aging-related diseases.
Royalty Pharma | December 08, 2020
Royalty Pharma, BioCryst Pharmaceuticals, Inc. what's more, Athyrium Capital Management, LP today declared exchanges adding up to $325 million in financing for BioCryst, with $250 million accessible at shutting, to help the dispatch of ORLADEYO™ (berotralstat) in genetic angioedema (HAE) and the advancement of its oral Factor D inhibitor, BCX9930.
Royalty Pharma will furnish BioCryst with a forthright money installment of $125 million and will get eminences of 8.75% on direct yearly net deals of ORLADEYO up to $350 million, 2.75% on deals between $350 million and $550 million, no royalty on deals over $550 million, and a layered level of sublicense income for ORLADEYO in specific domains. Likewise, Royalty Pharma will get a 1.0% royalty on worldwide net deals of BCX9930, whenever affirmed.
An asset oversaw by Athyrium Capital Management will give BioCryst a $200 million credit office, of which BioCryst will draw $125 million at shutting. The extra capital will be accessible in two tranches at BioCryst's alternative, after arriving at characterized income achievements. The credit office bears revenue at LIBOR +8.25% (with a LIBOR floor of 1.75%) and is revenue just for the whole five-year term, with all extraordinary head due at development. Also, BioCryst has the choice to pay revenue in-kind for the initial eight fourth of the term, permitting the organization to concede money premium installments until after this period. The organization will be dependent upon a base liquidity contract of $15 million. There are no other monetary agreements except if the third tranche is drawn by BioCryst.
BioCryst plans to contribute the joined continues to help the dispatch of ORLADEYO in the U.S. what's more, Europe and to propel the advancement of BCX9930 into clinical preliminaries in various supplement intervened sicknesses. Also, BioCryst will reimburse its current office with MidCap Financial.
"We trust ORLADEYO will be a groundbreaking medication and we are eager to cooperate with BioCryst to bring this oral, once-every day medication to HAE patients. In view of the empowering verification of idea information in paroxysmal nighttime hemoglobinuria with BCX9930, we likewise accept this oral Factor D inhibitor offers considerable open doors over different supplement interceded sicknesses," said Pablo Legorreta, Chief Executive Officer of Royalty Pharma.
"With a productive R&D ability, long IP on their items and huge close term business openings, BioCryst speaks to the ideal profile Athyrium looks for our speculations and we are eager to add to the organization's future achievement," said Hondo Sen, accomplice at Athyrium Capital Management.
"The generous monetary responsibility of extraordinary long haul accomplices like Royalty Pharma and Athyrium Capital Management empowers BioCryst to completely put resources into the dispatch of ORLADEYO and to quicken the advancement of BCX9930 to address a neglected requirement for patients and convey an incentive to investors. We accept the present financing mirrors the subsequent stage in the change of BioCryst," said Jon Stonehouse, Chief Executive Officer of BioCryst.
Cowen went about as monetary guide to BioCryst on the exchange. Gibson Dunn went about as lawful consultant to BioCryst. Goodwin Procter, Wolf Greenfield and Maiwald went about as legitimate counsels to Royalty Pharma. Hogan Lovells went about as lawful counselor to Athyrium Capital Management.