EU approves LEO Pharma’s psoriasis biologic

A new treatment option has been approved in the European Union for patients with psoriasis, paving the way for access to a novel approach for those with moderate-to-severe forms of the disease who are candidates for systemic therapy. LEO Pharma’s Kyntheum (brodalumab) is a novel biologic and the first and only psoriasis treatment to target the L-17 receptor. By binding to this specific receptor on the cells of the skin, brodalumab blocks the biological activity of several pro-inflammatory IL-17 cytokines involved in plaque formation, offering a different mechanism of action to all other psoriasis biologics currently available, which target free inflammatory mediators.