In response to bird flu pandemics starting in 2013, officials in China introduced a new vaccine for chickens in September 2017. Recent findings suggest that the vaccine largely worked but detected two new genetic variations of the H7N9 and H7N2 subtypes in unvaccinated ducks. These findings will be published in the journal Cell Host & Microbe on September 27.
"It surprised me that the novel, highly pathogenic subtypes had been generated in and adapted so well to ducks, because th...
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A Yale University study has found ibalizumab reduced viral replication and increased the count of immune cells in HIV patients, raising hopes for a new form of treatment for the disease. Approved therapies use a cocktail of nucleoside and nucleotide reverse transcriptase inhibitors to prevent viral replication, usually taken as a triple combination in case the virus develops resistance to one of the components. But ibalizumab has a different mechanism of action, binding to CD4, the main receptor...
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In a recent paper in Science Signaling, associate professor of cell and microbiology Carla Finkielstein, of the Department of Biological Sciences, and her collaborators identified an alternative mechanism to control circadian rhythms in normal cells that are driven by oncoproteins. This discovery places molecules involved in monitoring and calibrating the response of cells to genomic damage at the center of the machinery driving circadian rhythms.
Researchers are now discovering that mole...
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As the promise of CAR-T therapies becomes closer and closer, consumers are taking notice and lining up for the revolutionary cancer treatments that will soon be available from companies like Kite Pharma (KITE) and Novartis AG (NVS). But before the treatments can make it to patients, there are some logistical concerns that must be addressed. Unlike many other medications, CAR-T treatments are not able to be mass produced and stockpiled. The treatment is a lengthy process that involves reengineeri...
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Amazon's new Alexa upgrade offers some HIPAA-compliant skills—and some potential new opportunities for drugmakers that want to jump on the voice-activated AI platform. Amazon announced six partners last week in its first HIPAA-compliant nod for the voice apps it calls "skills." The partners, which include Express Scripts and Livongo, are offering apps that allow consumers to check on prescriptions, find urgent care and schedule visits, and log and track some health data. HIPA...
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Efficacy and safety of a therapeutic method has always been the prime concern during treatment of an ailment. Any therapeutic method that fulfills the above criteria has been deemed to be a successful procedure. Nonetheless, patients and health professionals not only seek the efficacy and safety of a treatment method, but also look into it being a non- invasive procedure involving minimal to no pain....
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