home.aspx
 
. https://www.genengnews.com/gen-news-highlights/novel-approach-could-lead-to-creation-of-new-thiophosphate-based-nucleotide-drugs/81256106
blog article
SHARESHARESHARE
NOVEL APPROACH COULD LEAD TO CREATION OF NEW THIOPHOSPHATE-BASED NUCLEOTIDE DRUGS
Scientists at Scripps Research and Bristol-Myers Squibb have created a novel tool for precisely controlling the stereochemistry of thiophosphates, found in some promising new drugs that target genetic molecules and other disease targets. Called phosphorus-sulfur incorporation (PSI), the technology acts like an atomic glue gun, binding nucleosides into oligomers with specific, preprogrammed spatial configurations at the thiophosphate linkage, according to the team.  SCRIPPS RESEARCH READ MORE