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How does a drug for colorectal cancer work?

September 25, 2019 / NOURAN AMIN

Colorectal cancer is a fatal and common disease, and treatment decisions are often based on what genes have been mutated in the development of the cancer. This means that certain patients with colorectal cancer may benefit from the chemotherapeutic ‘cetuximab’ while other patients may be unresponsive. However, the mechanism of how cetuximab works in those patients that do respond to treatment remains largely unknown--that is until a recent study published in the journal Science Signaling.