Epigenetic Drugs in Oncology: Current Clinical Landscape and Emerging Trends

| June 27, 2017

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Epigenetics is the study of heritable, reversible forms of gene regulation that are not dependent on the DNA sequence. This regulation includes DNA methylation and histone methylation, acetylation, ubiquitination, and phosphorylation. 1 While epigenetic modifications are crucial for normal functioning in all stages in life, from embryonic development through adulthood, these events are also associated with many cardiovascular, metabolic and neurological diseases as well as cancer.

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Hospital Samaritano

With 119 years of activity, the Samaritan is one of the country's leading centers of excellence in health. It has a Nucleus of Specialties with a focus on Cardiology, Gastroenterology, Neurology, Orthopedics, Oncology, Urology / Nephrology and Fetal / Perinatal Medicine. In addition, it has a complete and modern Service of Diagnostic and Therapeutic Medicine and Emergency area.

OTHER ARTICLES

Global Antiviral Drugs Market Growth: Is Antiviral Drug the Best Coronavirus Treatment?

Article | April 9, 2020

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How Pharma Companies Can Scale Up Their Knowledge Discovery with Semantic Similarity Search

Article | March 6, 2020

Pharma has deep roots in human history with centuries of folk pharmaceutical knowledge offering a hit-and-miss range of natural remedies. But the industry as we know it today actually emerged in the second half of the 19th century when the world’s first factory for the sole production of medicines was found. By the late 19th and early 20th century, some chemical companies had already begun using research labs to explore the medical applications for their products. Fast forward to today and the pharmaceutical sector is a global trillion-dollar industry. However, to ensure the safety and efficacy of drugs, the process of drug discovery and development is under extensive scrutiny and control on both national and global levels.

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Do Clinical Trial Delays Mean Trouble for Pharmaceutical Stocks?

Article | April 1, 2020

Pharmaceutical stocks have been somewhat of a safe haven for investors as the coronavirus outbreak spread from China to the rest of the world. But as the pandemic deepened, now resulting in more than 782,000 cases worldwide, even these "safer" companies are beginning to feel the effects. The U.S. is now the coronavirus epicenter, with the most cases -- more than 161,000 as of today. Initial concerns for drugmakers had to do with the supply of active pharmaceutical ingredients, which often come from China. The worry was that pharmaceutical companies wouldn't be able to produce enough of their drugs for patients.

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Clinical Supply Availability & Speed to Study Start-Up

Article | March 26, 2020

If you’re part of a clinical study team racing a new product to commercialization, you likely live by these two simple rules: time is money, and the first one to market wins. But just because it’s simple doesn’t mean it’s easy. That ticking clock is background noise to the responsibilities of regulations, study protocols, supply chains, and patient recruitment — all the details that must be worked out before a study can even begin. The pressure is always there. The longer it takes for a study to start, the longer it takes to complete.

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Spotlight

Hospital Samaritano

With 119 years of activity, the Samaritan is one of the country's leading centers of excellence in health. It has a Nucleus of Specialties with a focus on Cardiology, Gastroenterology, Neurology, Orthopedics, Oncology, Urology / Nephrology and Fetal / Perinatal Medicine. In addition, it has a complete and modern Service of Diagnostic and Therapeutic Medicine and Emergency area.

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