Efficient Removal of Aggregates from Monoclonal Antibodies

| December 26, 2018

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Monoclonal antibody (mAb) therapeutics have been widely used to treat various diseases, including cancer. Oftentimes, dimers and other high molecular weight aggregates are present in the mAb therapeutics, leading to reduced biological activity. Traditionally-used methods for aggregate removal rely heavily on anion exchange chromatography (AEX) in flow-through mode followed by a generic bind/elute polishing step.

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Masters Pharmaceutical, INC, ranked number 54 in Deloitte's top 100 largest privately owned companies in Greater Cincinnati and Northern Kentucky, is located in Cincinnati, OH.

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Masters Pharmaceutical Inc

Masters Pharmaceutical, INC, ranked number 54 in Deloitte's top 100 largest privately owned companies in Greater Cincinnati and Northern Kentucky, is located in Cincinnati, OH.

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