Efficient Cleaning-In-Place Methods For Protein-Based Antibody Affinity Chromatography Resins

| October 2, 2018

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Chromatography resins used for the production of biopharmaceuticals need to be cleaned efficiently to ensure the safety and efficacy of the bioproduct. Impurities that are not removed can build up on the chromatography column and start to leach into the process material in subsequent cycles. Efficient cleaning of the column in each cycle will prevent fouling and minimize the risk of carrying over between cycles and batches. Column fouling can also result in a  capacity decrease over time with a subsequent decrease in the resin lifetime.

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Luitpold Pharmaceuticals, Inc.

Luitpold Pharmaceuticals, Inc., a Daiichi Sankyo Group Company, consists of several divisions: American Regent, Animal Health, and PharmaForce Inc. We are innovators in the development, manufacturing, and distribution of sterile injectable products, and a reliable partner in providing pharmaceuticals which address diverse medical and veterinary needs. We manufacture and/or distribute over 100 different pharmaceutical products. Additionally, we provide contract manufacturing services for a number of leading companies.

OTHER ARTICLES

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Spotlight

Luitpold Pharmaceuticals, Inc.

Luitpold Pharmaceuticals, Inc., a Daiichi Sankyo Group Company, consists of several divisions: American Regent, Animal Health, and PharmaForce Inc. We are innovators in the development, manufacturing, and distribution of sterile injectable products, and a reliable partner in providing pharmaceuticals which address diverse medical and veterinary needs. We manufacture and/or distribute over 100 different pharmaceutical products. Additionally, we provide contract manufacturing services for a number of leading companies.

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