Drug compound could be next-generation treatment for aggressive form of AML

| January 29, 2019

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Purdue University researchers are developing a series of drug compounds that have shown promise in treating the recurrence of acute myeloid leukemia (AML). About 30 percent of acute myeloid leukemia (AML) patients have a mutation caused by a kinase called FLT3, which makes leukemia more aggressive. Inhibitors of FLT3, such as Radapt, approved last year by the US Food and Drug Administration, have shown a good initial response to treating leukemia. Gilteritinib, another FLT3 inhibitor, was recently approved toward the end of 2018. But AML patients on FLT3 inhibitor therapy often relapse because of secondary mutations in the FLT3 and existing treatments have not been fully successful in treating those cases.

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Since 1963 Cook Medical has worked closely with physicians to develop technologies that eliminate the need for open surgery. Today we are combining medical devices, biologic materials and cellular therapies to help the world’s healthcare systems deliver better outcomes more efficiently. We have always remained family owned so that we have the freedom to focus on what we care about: patients, our employees and our communities.

OTHER ARTICLES

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Spotlight

Cook Medical

Since 1963 Cook Medical has worked closely with physicians to develop technologies that eliminate the need for open surgery. Today we are combining medical devices, biologic materials and cellular therapies to help the world’s healthcare systems deliver better outcomes more efficiently. We have always remained family owned so that we have the freedom to focus on what we care about: patients, our employees and our communities.

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