COLD CHAIN, HOT TOPIC: The Challenge and Opportunity of Distributing Temperature-Sensitive Biopharmaceuticals and Cell Therapies

RACHEL GRIFFITHS | December 20, 2016

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Pharmaceutical industry interest in biopharmaceuticals, cell therapies and, more recently, biosimilars has increased significantly1,2. In addition to targeting and treating disease more effectively than small molecule medicines, such products have the potential to generate higher revenues and are less likely to face competition when they go off patent3,4. However, unlike small molecule drugs, which can be easily transported, large molecule biopharmaceuticals are highly sensitive to temperature fluctuations and require special handling5. Large molecule drugs are also more expensive to develop and manufacture than small molecule products, which means any lost as a result of problems during transportation have a higher financial impact6. Similarly, transporting cell therapies is a challenge7. While hydrogelbased alternative technologies are being developed, the vast majority of cell therapies are still shipped as frozen stocks8.

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OTHER ARTICLES

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How Pharma Companies Can Scale Up Their Knowledge Discovery with Semantic Similarity Search

Article | March 6, 2020

Pharma has deep roots in human history with centuries of folk pharmaceutical knowledge offering a hit-and-miss range of natural remedies. But the industry as we know it today actually emerged in the second half of the 19th century when the world’s first factory for the sole production of medicines was found. By the late 19th and early 20th century, some chemical companies had already begun using research labs to explore the medical applications for their products. Fast forward to today and the pharmaceutical sector is a global trillion-dollar industry. However, to ensure the safety and efficacy of drugs, the process of drug discovery and development is under extensive scrutiny and control on both national and global levels.

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At SA Health we are committed to protecting and improving the health of all South Australians. We do this by providing leadership in health reform, public health services, health and medical research, policy development and planning, with an increased focus on wellbeing, early intervention and quality care.

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