CD47: Regulation of cellular phagocytosis in cancer, inflammation & neurobiology

| October 11, 2017

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CD47 is a cell surface ‘don’t eat me’ signal that has been shown to be important in detection and evasion of cancer cells, inflammation, neuronal pruning and other path ophysiological processes. Blocking CD47 allows tumor cells to be recognized by phagocytes and this cell-cell interaction initiates a cascade of events resulting in tumor cell destruction. As such CD47 is an attractive target for the development of novel therapeutics.

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Rush University Medical Center

Rush University Medical Center is an academic medical center that includes a 671-bed hospital serving adults and children, the 61-bed Johnston R. Bowman Health Center and Rush University. Rush University is home to one of the first medical colleges in the Midwest and one of the nation's top-ranked nursing colleges, as well as graduate programs in allied health, health systems management and biomedical research. The Medical Center also offers more than 70 highly selective residency and fellowship programs in medical and surgical specialties and subspecialties.

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Spotlight

Rush University Medical Center

Rush University Medical Center is an academic medical center that includes a 671-bed hospital serving adults and children, the 61-bed Johnston R. Bowman Health Center and Rush University. Rush University is home to one of the first medical colleges in the Midwest and one of the nation's top-ranked nursing colleges, as well as graduate programs in allied health, health systems management and biomedical research. The Medical Center also offers more than 70 highly selective residency and fellowship programs in medical and surgical specialties and subspecialties.

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