Bacterial evolution of antibiotic arsenals provides new drug blueprints

| February 7, 2020

article image
Scientists from Trinity College Dublin have discovered that two very different species of bacteria have evolved distinct, powerful antibiotic arsenals for use in the war against their bacterial neighbours. By blueprinting precisely how the antibiotics function against methicillin-resistant Staphylococcus aureus (MRSA), the scientists have provided new options for drug designers seeking to hold back the global threat that antimicrobial resistance poses humanity. Failure to develop effective antibiotics that counter resistance to current drugs will have disastrous consequences. It is estimated that by mid-century, just 30 years from now, antimicrobial resistance will result in a global death rate of up to 10 million per year. By 2030, the World Bank puts the cost of resistance at US$3.4 trillion in global gross domestic product. The need for new and effective therapeutics is immediate and immense. The hope is that the basic research into the workings of an enzyme involved in bacterial coat synthesis reported in this article will contribute to the development of these urgently needed medicines.

Spotlight

PharmiWeb Solutions

We help pharma companies engage with patients, physicians and consumers through a range of digital channels. Combining digital and technology know-how with creative flair, we focus on what people want, need and find easy to engage with. We’re great to work with because whether you’re a brand manager, a digital expert, a scientist or a commercial manager, we talk your language.

OTHER ARTICLES

Pfizer Won’t Win the Coronavirus Pharma War

Article | March 6, 2020

Shares of Pfizer jumped more than 6% on Wednesday, after the company announced a plan to test some of its antiviral products as a potential treatment for the coronavirus from China. More than 35 million shares traded on the news — about 48% more than normal — as investors looked for any positive news from the pharma community after the recent selloff. So, does this mean that Pfizer stock is turning the corner?

Read More

3 Big Pharma Stocks Plunging the Most During the Coronavirus Stock Market Crash: Are They Buys?

Article | March 26, 2020

Big pharma stocks have been clobbered during the coronavirus-caused stock market crash. You can count the number of drugmakers with market caps of $25 billion or more whose shares haven't dropped by double-digit percentages on one hand -- and have several fingers left over. Three big pharma stocks have plunged the most: AbbVie (NYSE:ABBV), Bristol Myers Squibb (NYSE:BMY), and Pfizer (NYSE:PFE). But are these stocks smart picks to buy right now?

Read More

Do Clinical Trial Delays Mean Trouble for Pharmaceutical Stocks?

Article | April 1, 2020

Pharmaceutical stocks have been somewhat of a safe haven for investors as the coronavirus outbreak spread from China to the rest of the world. But as the pandemic deepened, now resulting in more than 782,000 cases worldwide, even these "safer" companies are beginning to feel the effects. The U.S. is now the coronavirus epicenter, with the most cases -- more than 161,000 as of today. Initial concerns for drugmakers had to do with the supply of active pharmaceutical ingredients, which often come from China. The worry was that pharmaceutical companies wouldn't be able to produce enough of their drugs for patients.

Read More

Pharmacist eCare Plan - the newest disrupter in health data exchange?

Article | February 25, 2020

Every member of the health care team shares a common goal of optimizing patient outcomes. Yet each specialty and position of the healthcare team has a unique workflow facilitated by various tools, from an operative report to a progress note. In this regard the pharmacist plays a pivotal function in medication management and requires documentation specific to that role. The Pharmacist eCare Plan (PeCP) allows for an interoperable note to be used in the pharmacy to assist in the exchange of patient information, including active medication list, laboratory results, and payer information. To allow for this, a new type of clinical document architecture for the PeCP was created and standardized for use across pharmacies.

Read More

Spotlight

PharmiWeb Solutions

We help pharma companies engage with patients, physicians and consumers through a range of digital channels. Combining digital and technology know-how with creative flair, we focus on what people want, need and find easy to engage with. We’re great to work with because whether you’re a brand manager, a digital expert, a scientist or a commercial manager, we talk your language.

Events