Abuse-Deterrent Studies for Controlled Drugs - A Changing Landscape

|

article image
Prescription drug abuse is the Nation's fastest-growing drug problem and has been classified as an epidemic by the Centers for Disease Control and Prevention.1 Abuse in this case can be defined as intentional misuse of prescription pharmaceuticals to obtain a desirable physiological or physical effect. Prescription drug abuse is the second most abused category of drugs after marijuana,2 and the abuse of opioid painkillers, primarily oxycodone, hydrocodone and oxymorphone, has become the largest component of prescription drug abuse in the United States. These drugs have typically been abused by chewing, crushing a tablet into a fine powder before snorting it, or dissolving a crushed powder in water before IV injection.

Spotlight

HealthMyne, Inc.

HealthMyne, Inc. (Madison, WI) leverages Point-of-Read quantitative imaging data to drive Point-of-Care clinical decision support workflow modules to enable better patient management decisions, impacting the cost and quality of care by reducing clinical variability.

OTHER ARTICLES

Global Antiviral Drugs Market Growth: Is Antiviral Drug the Best Coronavirus Treatment?

Article | April 9, 2020

The global antiviral drugs market has witnessed a rapid surge in demand due to the ongoing Covid-19 pandemic worldwide. So is antiviral drug the best coronavirus treatment? It is still too early to have that conclusion as many medical research and clinical trials are still trying to find the effectiveness and potential side effects of using antiviral drugs to treat coronavirus. But experts believe that antiviral drug might be the best hope for reduce the coronavirus transmission around the world at this stage. However, due to the current difficult situation of the supply chain in many lockdown countries and regions, there is a global shortage on the antiviral drugs supply. With researchers and manufacturers working hard to find and provide effective coronavirus treatment, it is expected that the global antiviral drugs market will have a significant growth over the near future. Antiviral drugs are a type of medication used specifically for treating viral infections, such as human immunodeficiency virus (HIV), hepatitis, and influenza.

Read More

Decentralized Clinical Trials: Imperative for Pharma Sector to fight COVID19

Article | April 9, 2020

These are unprecedented times. The world is mobbed by a contagion virus, putting people’s health at risk, threatening to destabilize economies. It has already put global healthcare systems under tremendous pressures, and managed to resist efforts to contain it. Even though coronaviruses are not new, this COVID-19 strain has created panic and forced us to be locked down in our homes sans any movement for weeks, if not months. Organizations are fighting an intense battle to keep their workforce safe, minimize risk, and ensure business continuity. For the Life Sciences industry, however, the challenge is even more significant. The whole world is looking at them to come up with a vaccine and a cure. But that is easier said than done. Bringing a new drug to market is an uphill battle and requires rigorous clinical trials. This process already has regulatory challenges. With the current lockdown situation, the Pharma community is grappled with the challenge of continuing some of the critical and time-sensitive in-flight trials so that their regulatory submission, registration, and market entry are not impacted. But all may not be lost. With the right technology solution, it is possible to turn the situation around rapidly.

Read More

What to Watch in 2020: Non-Specialty Drugs

Article | April 9, 2020

Pharmaceutical manufacturers are constantly working to develop new and improved medications. Join us as we explore the non-specialty drugs you should be watching in 2020. If you missed last week’s article about the most important upcoming specialty drugs, be sure to check it out here. Approximately 40 new medications are approved by the Food and Drug Administration (FDA) every year.1 (Please note: If you’re curious about what it takes to develop a drug and bring it to market, check out our previous article). Why should you care about these new medications? Because they can affect both your organization’s pharmacy spend and your members’ cost share. For non-specialty drugs, we will focus on medications that may come to market this year, including ones that are currently being reviewed by the FDA, or that are in the last clinical trial (Phase III) stage.

Read More

Comparing HydroxyChloroquine Trials

Article | April 9, 2020

One minor side effect of the pandemic is that perhaps more people will learn about what drug research and clinical trials can really be like. Today’s example: we have a clinical trial of hydroxychloroquine from Wuhan that has just published on a preprint server. What’s good is that this one is blinded, randomized, and controlled (like the earlier hydroxychloroquine which one I blogged about here from Zhejiang University, so we can actually talk about it rather than just spend all our time wondering what the heck is going on.

Read More

Spotlight

HealthMyne, Inc.

HealthMyne, Inc. (Madison, WI) leverages Point-of-Read quantitative imaging data to drive Point-of-Care clinical decision support workflow modules to enable better patient management decisions, impacting the cost and quality of care by reducing clinical variability.

Events