A Cure for Pharmaceutical Supply Chain Complexity

| July 26, 2017

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The pharmaceutical industry lags in the sophistication and performance of its supply chains when they are compared with best-in-class companies in other industries. This is due to the complexity that has come with new drugs, more complex production technologies and evolving regulatory requirements. In this environment, integrating and aligning the supply chain makes it more flexible, bolstering operational performance and financial competitiveness. The complexity of drug product supply chains has increased in recent years thanks mainly to the development of more complex chemical molecules (with more synthesis steps), more suppliers and geographies in the chain, and reduced average production volumes. Preparing for commercial release, the time from raw material to finished drug product can be as long as two years, and those months are fraught with hazards that can cause delays and rework, leading to extra costs, stock-outs and poor capacity utilization.

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Vel Vaccines Biosciences

VEL (Variable Epitope Library) vaccine technology was developed to address the need for effective immunization strategies against antigenically variable targets. The main limitation of current technologies is their inability to elicit sustained, protective immune responses against these constantly changing targets. VEL vaccines anticipate large numbers of mutational outcomes in the target and challenge host immune defenses with thousands and tens of thousands of epitopes. Immune systems primed with VEL-vaccines produce unprecedented repertoires of T-cells capable of containing and neutralizing disease caused by antigenically variable targets.

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