RESOURCES

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Jan 30, 2020

Dr. O’Day: I think we’re actually on the cusp of making precision medicine real. The term’s been around for quite some time and I think we might have gotten a little ahead of ourselves because we saw a technology that could have impact. And over the past 5, 10 years we’ve bee...

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Jan 30, 2020

Prices for drugs should reflect their value. If price and value become disconnected, efforts to produce new therapies won’t focus on the treatments with the highest net benefit for patients and payers. A challenge arises when the value of a drug is uncertain. Durable drug therapies such as gen...

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Jan 28, 2020

Drug Target Review explores the latest applications of stem cells in modelling disease, drug production and the most recent steps in regenerative medicine provided by research.For decades, researchers have been investigating how to steer stem cell differentiation to create models and engineer tissue...

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Jan 28, 2020

For many industries, the thought of a post-Brexit world can be a fearful one; the repercussions are mostly unknown and negative news stories, statistics and economic predictions all contribute towards a nail-biting outlook on a fast-approaching reality. However, there is one sector that may actually...

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Jan 22, 2020

Any compounds you use during drug discovery and development have started their journey long before they ended up in your lab. They have been collected, stored, processed, and then finally delivered to your bench. The process of compound management is highly complex and requires input from a number o...

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Jan 22, 2020

No matter who you are or what your station in life may be, the dream of good health and longevity for ourselves and those we love is a dream we all share. Unfortunately, for far too many of us nowadays, that dream also comes with a hefty price tag, one that fewer and fewer Americans are able to pay....

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Jan 20, 2020

Will AI be the 21st century's biggest cause of unemployment or the largest driver of sales growth? People in every industry are concerned that Artificial Intelligence will soon cause them to lose their jobs. Others say it will revolutionise the way we work. Who is right and what are the conseque...

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Jan 20, 2020

The FDA has recently approved two generic versions of apixaban and from the amount of apixaban I’m seeing used in clinical practice, this is a great thing for overall healthcare and drug costs. Here’s the FDA’s statement. Because of this switch to generic apixaban availability as w...

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Jan 16, 2020

The Pharmacy sector has become one of the most interesting sectors in retail because of the expanding ambitions of some of its leading players, and the appeal from the potential entry of retail’s largest giants. We broke down some of the sector’s classic leaders to see who’s positi...

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Jan 16, 2020

As the biopharma industry concludes its annual pilgrimage to San Francisco for the JP Morgan investor conference, much of the talk around town inevitably was about gene therapies. Rightfully so, considering the therapeutic promise of such one-time cures, and the spate of M&A activity for gene th...

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Jan 14, 2020

If you’re reading this now, chances are you’re doing so with a bit of anxiety … and your anxiety is justified by the December 1, 2019 deadline for United States Pharmacopeia (USP) Chapter <800>. You’re not alone. Other compounding facilities are in a rush to make physi...

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Jan 14, 2020

The PBM industry saw some significant changes in 2019, as some of the largest forces in the market vertically integrated and began implementing disruptive programs that redefined the way pharmacy claims are processed in the U.S. The disruptive strategies spanned from drug acquisition (the way PBMs n...

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Jan 10, 2020

Every month, our Industry Relations Director, LeAnn Lewis provides an in-depth industry update to customers. Below, you will find an agenda for the industry update for January. If you have any questions regarding any of the points, contact us here.

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Jan 09, 2020

The medical device industry has experienced a boom in recent years, this has gone hand in hand with the development of state-of-the-art devices that provide greater benefits to patients. Medical devices are instruments and implements used in the diagnosis or treatment of various pathologies; Medical...

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Jan 08, 2020

Every year, the patents on prescription drugs expire, allowing other manufacturers to produce generic versions of brand-name drugs. In past years, drugs like Claritin became loratadine, Prilosec became omeprazole, and Pravachol became pravastatin. Each time a brand-name drug becomes generic, we save...

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Jan 08, 2020

Cold and flu season is here. The common cold, often caused by rhinoviruses, is the most common human illness and comes with generally mild symptoms. The flu, caused by the influenza virus, can have more complicated symptoms. Both are contagious. So, what can you do to not get sick? That’s a qu...

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Jan 06, 2020

Last Friday (3 January 2020) the Advisory Council on the Misuse of Drugs (ACMD) published a new report on the Misuse of Fentanyl (and Fentanyl analogues). As many readers will know, Fentanyl is a licensed medicine used for anaesthesia and pain management. Like morphine, heroin, codeine and other &ls...

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Jan 06, 2020

I’m optimistic about what 2020 and the new decade holds for your pharmacy and all independents across the country. That’s because there are opportunities for you to take advantage of four new performance trends. Each gives you the chance to show payers the great care that you provide to ...

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Jan 02, 2020

Before heading toward a detailed view about third party manufacturers of medicine, we first need to know that what really third party medicine manufacturers are? And how they work? So we can simply understand or define a third party medicine manufacturer as that outsource when a company or manufactu...

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Dec 27, 2019

Pharma franchise is an agreement or authorized permission or sanction established by pharma company to suppliers, group or separate company Franchise Company offers privileges to franchisee to expand its business with the benefit of Franchise Company. In the past few years, it has been seen a tremen...

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Dec 20, 2019

Recently, there has been discussion in the industry regarding the utility of polymer-based vial containment systems for the storage and transport of gene therapy drug products, which can be performed as low as -80oC. Since it is known that all polymers are gas permeable, discussion has centered on w...

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Dec 20, 2019

Kratom is a mind-altering substance that has bounced on and off the radar for the last decade. Occasionally, we’ll hear news blurbs about this drug, a story here and there of someone who died from using it. But the substance is still legal, and there is even a strong advocacy movement to keep ...

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Dec 18, 2019

Building meaningful relationships with HCPs is key to pharmaceutical sales success, and so it’s crucial for medcomm agencies. In this blog, we’ll show you how you can start using speaker program technology to increase engagement with HCPs and pharma for better program ROI. Life Science c...

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Dec 18, 2019

What’s the best way to improve performance and optimize the care of patients using the EQuIPP™ platform? The answer is quite simple. Education and teamwork! After a recent user group meeting, it’s clear that pharmacists are striving to improve adherence and want to know better ways...

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Dec 16, 2019

One of the company's affiliates is pushing hard to market naloxone, an anti-overdose medication. “You’re in the business of selling medicine that causes addiction and overdoses, and now you’re in the business of selling medicine that treats addiction and overdoses?” asked...

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Dec 16, 2019

We often get requests like this one: "We're experiencing a massive spam URL injection issue on our site. Almost every page on our site has unauthorized pharmaceutical ads with links to seller sites. Please help!" What has hit them is the "pharma hack." Website owners too ofte...

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Dec 12, 2019

It has been a busy week for studies focusing on complex care in older adults. Two new studies provided some insight on the amount of medications older adults use, and the problems they are having with these medications. Here are links to the articles: Polypharmacy and Pharmacological Treatment of Di...

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Dec 12, 2019

As online businesses expand on a day-to-day basis, the pharmaceutical industry isn’t being left behind. The statistics speak for themselves. In 2014, the global online pharmacy market was estimated to be worth 29 billion U.S. dollars on average. And by 2023, it’s predicted that the marke...

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Dec 10, 2019

New research from CRA looks at the relationship between rarity of a disease and the price countries are willing to pay for drugs to treat them. High clinical development costs and small target patient populations have often been presented as justifications for high prices of drugs to treat rare dise...

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Dec 10, 2019

Reduction in the price of prescription drugs is a rare event. Several factors could be responsible for a decline in prices that affects the overall pharmaceutical industry. The US witnessed 1% reduction in the prices of prescription drugs in 2018, as revealed by the government. Despite the modest de...

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Dec 02, 2019

For capitalism’s critics, the opioid crisis is a powerful witness for the prosecution. They charge that inequality, stagnant wages, immobility, job loss — the four horsemen of the neoliberalism endgame — have generated a massive surge in “deaths of despair,” especially ...

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Dec 02, 2019

Artificial Intelligence and Machine Learning are powering incredible changes across a huge range of industries. But in data and research-dependent industries such as pharmaceuticals, they’re having an unparalleled impact. From improving candidate selection processes for clinical trials, to acc...

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Nov 29, 2019

Barely a week goes by without one big pharma or biotech announcing that it is using AI to develop new medicines. Richard Staines looks at the progress already made thanks to this potentially revolutionary technology, and how it could change the fortunes of a beleaguered pharma industry. Artificial I...

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Nov 28, 2019

A key component of product innovation in the pharmaceutical industry is the analysis of data. Yet, the Pharma industry can be diagnosed as suffering with one particular problem: the prevalence of data silos. Often stored across disparate tools and locations, the isolation of data severely impacts th...

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Nov 28, 2019

The modern pharmacy retail segment is welcoming an exciting new entrant in Japanese drug and cosmetics retailer Matsumotokiyoshi Co., Ltd, urging existing players to dust down their racing goggles. Matsumotokiyoshi has agreed to form a joint venture with Lotus Food Group JSC to operate a drugstore c...

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Nov 28, 2019

One downside of the antibody-drug conjugates used in oncology today is that the drug-carrying antibodies can shed much of their toxic cargo on the way to the tumour site. Now, German researchers have published their method for attaching drugs to antibodies with greater stability, potentially making ...

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Nov 27, 2019

A new program in Glasgow will give drug users pharmaceutical-grade heroin twice daily in a bid to reduce drug-related deaths. Homeless drug users in Scotland will be allowed to inject pharmaceutical-grade heroin twice a day under the supervision of medical officials as part of a new program intended...

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Nov 27, 2019

One of the great benefits of smoking marijuana is that there’s rarely any hangovers on the following day. Sadly, the plant still has the capability of rattling your memories. Cannabis, or THC more precisely, tends to affect people’s cognitive function and short term memory skills, which ...

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Nov 25, 2019

The pharmaceutical industry is adopting artificial intelligence (AI) on numerous fronts, from discovery and clinical development to risk assessment and safety monitoring, regulatory, and manufacturing. Pharmaceutical and biotechnology companies, as well as service providers now, rely on AI technolog...

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Nov 22, 2019

When it comes to shipping pharmaceuticals, we use cold chain materials to control the temperature of your drugs or medicines from the manufacturer through a delivery to the end user. It’s critical to keep these within the proper temperature range because they can be rendered useless or even ha...

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Nov 22, 2019

Innovation with the Internet of Things(IoT) has been an on-going effort. Although IoT appeared in the Gartner hype cycle for 2017, it has been around for a very long time and businesses have experimented with this technology since the time we can remember. It’s only in the recent past that cos...

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Nov 22, 2019

The ultimate value that robotics data will provide is in improving outcomes through better recording of process, approach, measurements and outcomes data. Collected through an individual robot in one OR, that data is likely interesting, but not significantly valuable. It’s also not linked to t...

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Nov 21, 2019

Artificial intelligence (AI) and machine learning (ML) are not yet perfect sciences, but they are transforming life sciences companies in practical and meaningful ways. This includes improving targeting and relationships with healthcare providers (HCPs) and patients. However, organizations need to b...

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Nov 21, 2019

Registered qualifying patients under the Compassionate Use of Medical Cannabis Pilot Program Act, are granted certain exceptions for possession volume and cultivation of cannabis. Further, the CRTA does not permit any person to smoke cannabis in any place where smoking is already prohibited under th...

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Nov 21, 2019

If you are a business owner you might know advertising can be challenging at times, especially if you are an owner of a Cannabis Dispensary or CBD Shop. You are not sure where to start. You might ask yourself do I need someone to help me with this? What are the laws, rules and regulations for advert...

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Nov 21, 2019

Vaccines have been established as the most effective method of preventing flu since the early 20th century, however, much has changed in the past century to improve effectiveness, administration and adherence in the face of flu viruses’ constant mutation. Allie Nawrat charts the development of...

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Nov 20, 2019

The global pharmaceutical market is expected to grow to almost 1.2 billion by 2021,1 thanks in part to rapid advancements in digital automation and innovation. Unfortunately, these growth-generating strategies also open pharma manufacturers up to new risks. For example, acquisitions and outsourcing ...

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Nov 20, 2019

In drug discoverers’ jargon, large collections of molecules are known as chemical spaces. Whereas chemical spaces only contained a few million molecules some years ago, they now hold tens of billions of molecules. In addition, previously “virtual” molecules can now be purchased and...

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Nov 19, 2019

The U.S. pharmaceutical supply chain is responsible for providing patients safe, secure and timely access to more than 4 billion prescription medicines every year. Sustaining this complex supply chain requires the collaboration between a diverse group of partners, including manufacturers, distributo...

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Nov 19, 2019

It happens all the time across the pharmaceutical industry: you’ve been tasked with understanding customer perceptions better, but your budget and timelines are limited. In these situations, an Advisory Board can be an incredibly valuable tool. Advisory Board meetings help manufacturers seek a...

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Nov 18, 2019

Growing up in Tanzania, I knew that fruit trees were useful. Climbing a mango tree to pick a fruit was a common thing to do when I was hungry, even though at times there were unintended consequences. My failure to resist consuming unripened fruit, for example, caused my stomach to hurt. With such in...

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Nov 18, 2019

For as long as there have been people, there have been illness and disease to hobble them. From cancer to the common cold, these nemeses of the human condition aren’t just going to disappear overnight. But medical researchers are still making major headway in how we diagnose and treat differen...

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Nov 18, 2019

Innovation in pharma is playing a key role in transforming science, healthcare and even the wider society. From the chance discovery of penicillin to the Human Genome Project – one of the world’s largest collaborative scientific endeavours – we have seen the eradication of devastat...

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Nov 15, 2019

Drug pricing regulations would not decimate the pharmaceutical industry, according to an analysis from health policy researchers at West Health and Johns Hopkins. This throws some cold water on Big Pharma's claims that new drug research and investments would evaporate if the federal government l...

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Nov 15, 2019

The way to accelerate benefit to patients changes over time as technology improves and innovation becomes more cutting edge. I’ve always looked for the more cutting-edge projects because, quite frankly, they’re just more intellectually stimulating for me. I like being on the vanguard whe...

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Nov 14, 2019

Today - with a full year of newsletter coverage - I would like to present excerpts from a new evaluation. All of the following figures relate to the period from January to October 2019. In January of this year, we once again dramatically increased the number of subscribed newsletters - from 100 to 2...

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Nov 14, 2019

Pharmaceutical communication is a foundational component of stakeholder engagement and management. In Europe, pharmaceutical communication traditionally focuses solely on interaction with prescribers, while in the US pharma communication also includes direct-to-consumer advertising. Strategic engage...

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Nov 12, 2019

With medicine adherence still a major problem for pharma and healthcare systems, a collaboration between Cognitant Group and Addenbrooke’s Hospital –supported by grants from UCB and Pfizer – is piloting a programme that aims to educate patients through the power of virtual reality ...

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Nov 12, 2019

Cannabis comes with a lot of known health benefits to users with little to no side effects, unlike pharmaceutical drugs. Advancement in technology now allows manufacturers to extract various products infused within cannabis such as extracts, concentrates, edibles, etc. The use of ethanol in extracti...

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Nov 12, 2019

The use of cannabinoids to treat PTSD is becoming a much more common treatment regime. Historically, cannabinoids were difficult to prescribe, as national legislation restricted scientists from studying their therapeutic efficacy. Without this research and with the lack of a product monograph, in th...

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Nov 11, 2019

AI, in practice, has a lot of potential and also a lot of limitations. AI is being used to model, extrapolate, and automate tasks throughout the lifecycle of a drug (as it should be). The potential benefits are substantial, both in terms of clinical efficacy and financial savings. The low-hanging fr...

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Nov 11, 2019

The term "process chemistry" describes the action of "scaling up" reactions – taking small quantities of a chemical compound and synthesizing it on a much greater scale. A process chemist is tasked with developing synthetic routes that are safe, cost-effective and efficient...

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Nov 11, 2019

Last year, the FDA approved 59 new molecular entities for the US market, the highest number ever approved in a single year. A key driver of this record level of approvals is the explosive growth of precision medicine. Since 2015, at least a fifth of all new drug approvals each year have been precisi...

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Nov 08, 2019

Drug discovery is the process of identifying new medicines for treating or curing human diseases. While drug discovery has led to many life-saving and life-enhancing clinical treatments, historically the process has also been long, expensive, and often unsuccessful, with many areas of unmet need sti...

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Nov 08, 2019

Over the last decades, the advances in medical science, the growing competition and the demands of the payers have led to permanent changes and adaptations of the pharma business model. Even the biggest companies do not do everything in-house. Instead, the industry has developed partnering as one ke...

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Nov 06, 2019

There are many aspects of drug development that must be understood before a drug can be tested in humans. Nonclinical studies are conducted to understand the safety (i.e., toxicity and safety pharmacology) of drug candidates and to provide critical pharmacokinetic (PK) information, including insight...

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Nov 06, 2019

A team comprising over a dozen chief quality officers (CQOs) representing the medical device, pharmaceutical, animal health, and consumer healthcare industries has pooled its collective passion and wisdom—with input from FDA and other drug and device regulatory agencies—to establish and ...

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Nov 06, 2019

A research group at the medical devices and health care giant Abbott has discovered a new strain of human immunodeficiency virus, or HIV—the first to be identified in 19 years. Abbott continues to look for potential new HIV strains to ensure that diagnostic tests for blood screening and detect...

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Nov 06, 2019

It’s 2019. If technology is integrated into our daily lives when it comes to work, entertainment, and even social interactions, it shouldn’t come as a surprise that tech is also playing a major role in improving health outcomes. A 2018 study showed that 90% of Americans use digital healt...

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Nov 05, 2019

A joint Harvard-Eisai project has achieved a breakthrough by fully synthesising the highly potent anti-cancer molecule halichondrin, sourced from marine sponges, at scale. It has taken 30 years of research to reach this point, so what has made halichondrin synthesis so difficult, and what are the im...

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Nov 05, 2019

The launch of a new product can be a daunting task. The main reason this happens is that no matter how many times your company has managed to enter new products on the market, chances are that not one initiative entirely resembled another. For better or for worse, there is not a single recipe for su...

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Nov 03, 2019

Healthcare is an industry that is as of now being changed utilizing the most recent technology, so it can address the difficulties it is looking in the 21st century. Technology can help healthcare associations satisfy developing need and proficiently work to convey better patient consideration. Here...

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Nov 01, 2019

Pneumococcal disease, defined as infections caused by the bacterium streptococcus pneumoniae, has long been a source of morbidity and mortality, particularly in infants and the elderly. Importantly, rates of pneumococcal disease have been significantly curtailed, largely in developed regions, due to...

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Nov 01, 2019

Metabolic disrupters, phages, and other approaches are going to be needed to treat the broadest possible range of patients infected by bacterial pathogens resistant to multiple drugs. In the summer of 1924, Calvin Jr., President Coolidge’s youngest son, developed a blister in his third right t...

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Oct 31, 2019

Health authorities worldwide have overseen the recall of many ‘sartan’ products in the past few years. These recalls began in the US as early as 2013 with a recall of product by Teva Pharmaceuticals. Authorities in the US, EMA, Canada, and Australia, just to name a few, have taken enforc...

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Oct 30, 2019

A decade ago, precision medicine was little more than an idea and a phrase. The term was coined in 2011 by the National Research Council, a non-government agency that advises the government on scientific matters. That year, the NRC issued a report calling for a new “data network” to brin...

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Oct 25, 2019

Artificial intelligence (AI) has been trumpeted by many in the pharmaceutical industry as the magic bullet to the issues they face in drug discovery and other research. However, expectations need to be tempered because although it’s easy to get excited by the potential of AI it’s importa...

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Oct 24, 2019

An engineered small molecule called opabactin that targets the receptor for the hormone abscisic acid (ABA), which plants release in stressful conditions, limited water loss in Arabidopsis, tomato, and wheat, and improved wheat’s tolerance of drought-like conditions in the lab, according to a ...

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Oct 24, 2019

At its Connect conference in London in early October, MuleSoft brought together its customers and clients across all sectors to discuss how enterprise software, and particularly APIs, can drive efficiencies and contribute to digital transformation. Mulesoft’s David Chao and AstraZeneca’s...

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Oct 24, 2019

Ninety-seven percent of potential new cancer drugs never make it to market, dropping out of clinical trials when they don’t meet measures of safety or efficacy. “Why that is, we don’t really know. But I think that this extremely high failure rate suggests that there are some fundam...

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Oct 23, 2019

Artificial intelligence has been much discussed of late, but will it really help us solve important problems like how to bring personalized medicine to as many patients as possible? Kate Hilyard, COO of Healx in Cambridge in the UK, believes it can. Getting a drug to clinical trials currently requir...

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Oct 23, 2019

A drug’s efficacy can be impacted significantly by the way in which it is delivered. By developing a variety of drug delivery systems (DDSs) it is now possible to better control the pharmacokinetics, pharmacodynamics, toxicity, immunogenicity and efficacy of drugs. By finding the best-suited d...

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Oct 22, 2019

Maintaining robust quality control standards is a key priority for any commercial industry – but for pharmaceutical manufacturers, it can literally be a matter of life and death. The medical sector is one of the most stringently regulated in the world, and drugmakers recognize the importance o...

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Oct 22, 2019

In most randomized pharmaceutical clinical trials, researchers are looking for a statistically significant performance difference between the two courses of therapy. But which is more important to the patient: Statistically significant improvement of a variable, or clinically significant improvement...

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Oct 21, 2019

Your neighbor is telling you about his new baby. He feels nervous about vaccinating, and says he's considering delaying Lucy's vaccines. Your mother's group is chatting about vaccines. One mother tells the group Jimmy isn't vaccinated, and she's using the Immune-Strengthening Die...

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Oct 21, 2019

Since the 90s, the requirements for pharmaceutical companies to register and report results from clinical trials have increased. But analysis published in the BMJ indicates that large pharmaceutical companies could be doing much more when it comes to sharing data. Over the last few decades, pharma c...

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Oct 18, 2019

Water plays a vital role in a broad range of processes within the pharmaceutical industry, from its use as a reagent and solvent in drug synthesis, to its utilization in formulation development and analytical testing, all the way through to product packaging and labeling. Each application has its ow...

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Oct 17, 2019

Presently 33 states and the District of Columbia have enacted medical marijuana laws. While some of these laws have been on the books for several years, the impact on employers and company policies are still evolving. This issue has created confusion for federal contractors who are required to compl...

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Oct 17, 2019

A new fungus discovered in the estuarine waters of Tasmania could be the unexpected answer to the world's opioid crisis, a current study suggests. Opioids — many of which are prescription painkillers, such as codeine — have created a worldwide health crisis. Many opioids are highly a...

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Oct 16, 2019

The CBD industry is flourishing, conservatively projected to hit $16 billion in the United States by 2025. Already, the plant extract is being added to cheeseburgers, toothpicks and breath sprays. More than 60 percent of CBD users have taken it for anxiety, according to a survey of 5,000 people, con...

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Oct 16, 2019

The best ways to keep your facility clean. Pharmaceutical facilities, especially those manufacturing biological products or sterile dosage forms, present considerable cleaning challenges. They must be: designed to be cleanable and maintained, tested for cleanliness, and cleaned thoroughly.

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Oct 16, 2019

New research by The Worldcom Public Relations Group has ranked pharmaceutical companies according to their usage of digital channels – with Bayer, Pfizer and Boehringer Ingelheim coming out on top. However, the report – called the Digital Health Monitor – also notes that many large...

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Oct 15, 2019

When a pharmaceutical company raised the price of an essential medicine to unacceptable levels, there was only one thing for pharmacist Marleen Kemper to do: start making it herself. When Kemper was in primary school, she had watched two of her classmates get ill. One had a brain tumour, the other c...

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Oct 15, 2019

Almost all patients with the vaping-related illness have ended up hospitalized, according to the Centers for Disease Control and Prevention. About half of people with the lung illness end up in the intensive care unit. Twenty-six people have died from the disease, and nearly 1,300 people have gotten...

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Oct 14, 2019

Despite the important role of intellectual property rights in incentivizing innovation, the patenting of pharmaceutical innovation is frequently accused of impeding access to medicine. Criticism of the prevailing patent regime has focused in particular on patents directed towards follow-on pharmaceu...

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Oct 14, 2019

Genetic testing has become an increasingly buoyant area for deal making in recent years. While the pharma industry has been experiencing price pressure and low R&D productivity, the recent market ambition for “Precision Medicine”1 has driven interest and growth in clinical genetics a...

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Oct 11, 2019

Sometimes it’s the really small things that make a huge difference to a person’s health. Skipping dosages of prescription medication, for example, has been linked to an array of negative effects. About half of us are guilty of not taking medication correctly, according to figures shared ...

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Oct 10, 2019

A receptor (drug target) can shift from a single subunit to a multi-structure in the presence of a ligand (drug compound) – a process known as "oligomerization". Having a method to determine exactly how different drug compounds target the same receptor is key to understanding why and...

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Oct 10, 2019

Pharmacist preregistration trainees are full-time employees, so they need to adjust to a new work environment, study for the registration assessment and juggle their everyday commitments. The preregistration year is stressful, but for hard-working and disciplined individuals, it pays off. And in ret...

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Oct 10, 2019

The United States is a huge economy and the economies look up to it for inspiration on how to manage the country to yield maximum output from the economy. But the medicines and drugs in the country are something that has always been on the controversial aspects of the country.

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Oct 09, 2019

Cambodia remains one of the poorest countries in the world following the devastating activities of the Khmer Rouge regime of the 1970s, and the standard of its health care is variable. In 2018, I spent two weeks scoping out potential opportunities to improve patient safety at a provincial hospital i...

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Oct 07, 2019

With traditional drug development, the FDA typically focuses the majority of its attention on clinical aspects of a drug. With advanced cell and gene therapies, the agency places far more focus on chemistry manufacturing and controls (CMC) much earlier in development. Due in part to the fact that th...

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Oct 07, 2019

According to information gleaned from a drug tracker, more than 100 drugs regularly prescribed by GPs are now out of stock, and this is forcing patients to ‘chop and change’ between medicines. The tracker showed that a total of 106 products were unavailable earlier this month, while a fu...

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Oct 04, 2019

Effective teamwork is crucial for any pharmaceutical company. Whether it's an outstanding sales manager, establishing the company’s brand, or a medical advisor, managing clinical trials by company guidelines, everyone on your team needs to be engaged and focused on the same goals to facili...

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Oct 04, 2019

Clinical Study and Technology are two such genres that are progressing at a rapid rate. The implementation of age old practices does not suffice in any of the scenarios. Clinical trials are common in pharmaceutical industries and they occupy a major part in the approval of a drug. If the process of ...

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Oct 02, 2019

When you smoke, vape, or eat cannabis, you obtain the cannabinoids THC and CBD from any of the thousands of different strains of cannabis plants. Until now, this was really the only way to get those cannabinoids, and trust me, it worked great. But a recent announcement from a man who knows more abou...

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Oct 02, 2019

How does artificial intelligence (AI) rank in the minds of pharmaceutical executives? How important is it in their eyes, and how does it compare to other trends? Although the buzz around AI has never been bigger, that’s not to say that every leader in pharma has bought into the hype yet. The D...

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Oct 01, 2019

Since the Hatch-Waxman Act of 1984 created an abbreviated regulatory approval pathway for generic pharmaceutical drugs in the U.S., generics have made tremendous strides in bringing down the cost of many medical treatments and even come to dominate some therapeutic areas.

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Oct 01, 2019

American family clinics, such as the Planned Parenthood Institute, first help women stop pregnancy . And immediately after, with half-closed doors, a very profitable journey begins. The aborted fetus is dissected in different parts, liver, kidney, thyme, skin, which are sold. A liver can cost up to ...

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Sep 30, 2019

The long-hoped for regulatory information management (RIM) transformation has yet to be achieved. As Steve Gens and John Cogan note in their recent paper — The Promise of Enterprise RIM – What’s Slowing the Innovation Potential? – the conversation all-too-often turns to issue...

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Sep 30, 2019

A global study on attitudes toward dementia has shown that two-thirds of people believe it to be a natural risk of getting older, which could be limiting the help that people seek. Every 3 seconds, someone develops dementia somewhere in the world. In the United States alone, 5.8 million people are l...

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Sep 27, 2019

Forward-thinking Pharma companies recognize that when evaluating ROI on the patient experience, they need to think beyond finances. PX impacts trust in the brand and reputation in the industry. In the context of the recent Gallup poll on consumer perceptions where the pharma industry rated below ele...

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Sep 25, 2019

The FDA grants Orphan Drug Designation to treatments for rare diseases in R&D; here are the 10 most recent for oncologic conditions. The US Food and Drug Administration’s (FDA) Orphan Drug Designation (ODD) denotes medications that are potential promising treatments for rare diseases in th...

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Sep 25, 2019

Colorectal cancer is a fatal and common disease, and treatment decisions are often based on what genes have been mutated in the development of the cancer. This means that certain patients with colorectal cancer may benefit from the chemotherapeutic ‘cetuximab’ while other patients may be...

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Sep 25, 2019

To tackle the challenge of medication adherence, particularly in the clinical trial space, UK health tech company Elucid has created a smart pill bottle and mobile app called Pill Connect. Currently in the trial stage, Pharma Tech Focus talks to Elucid’s CEO Dr James Burnstone about how the sy...

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Sep 24, 2019

Most of the drugs that are taken off the market are removed for reasons other than safety. However, sometimes drug makers choose to remove drugs from the market even if there is no problem with their safety profile. In fact, from 1994 through 2015, 215 drugs were withdrawn from sale, and only 5.1 pe...

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Sep 24, 2019

A normal dosage of cough syrup has 15 to 30 milligrams of DXM. Most doctors recommend that you do not take more than 30 milligrams over a 24-hour period. It takes between 300 and 1,000 milligrams of DXM to get high. DXM can cause euphoria that ranges from a mild buzz to hallucination or an out-of-bo...

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Sep 23, 2019

The US now has only a decade to achieve both universal health coverage and to prevent and treat substance abuse under the United Nations’ 2030 Sustainable Development Goals. Katherine Pettus argues that adopting a single-payer public health system is likely to be the only way to achieve these ...

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Sep 20, 2019

A lot of media coverage about counterfeit drug threats in the U.S. are spurred by the media relations efforts of organizations funded by pharmaceutical companies, such as the Alliance for Safe Online Pharmacies and Partnership for Safe Medicines. As I see it, their public education efforts conflate ...

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Sep 20, 2019

Biosimilar therapies are copies of large-molecule, biologic drugs. They differ from generics in that they are not exact copies of the original drug but, rather, a similar molecule that delivers an equivalent clinical outcome to the branded drug. Where small molecule drugs comprise 10s of atoms, biol...

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Sep 19, 2019

The US Food and Drug Administration (FDA) recently approved Zolgensma, Novartis’ one-dose gene therapy for the treatment of paediatric patients (less than two years of age) suffering from spinal muscular atrophy (SMA), a rare but life-threatening disease. Zolgensma was acquired by Novartis as ...

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Sep 18, 2019

The adoption of Artificial Intelligence (AI) in research-intensive organizations has essentially seen linear growth in recent years. Pharmaceutical, CRO, university and healthcare organizations are beginning to shift away from theoretical plans to genuine practical applications of machine intelligen...

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Sep 18, 2019

The difference between opioids and opiates is subtle enough that most people use the words interchangeably. After all, they both come from the poppy plant. The biggest difference is that opiates are natural drugs and opioids are synthetic drugs. They both have the same effect on the mind and can cau...

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Sep 18, 2019

CBD and products like it seem to be making an immediate splash in healthcare as of late. But, how has this controversial product gained such rapid success? Across the country more and more companies are popping up selling CBD products ranging from oils to dog treats.

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Sep 17, 2019

The Finnish pharmaceutical company Orion Pharma, with help from Reaktor AI, has been on a journey to introduce AI into company operations across the board, to fully utilize all available data, and to build the capability to quickly adapt in an ever- changing world. In other words, their goal is to b...

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Sep 16, 2019

Key Opinion Leaders (KOLs) are experts in their field and a respected voice in medical circles. They have an influential quality coveted by companies within the pharmaceutical industry. In this blog, we look at the role of KOLs and the 5 steps to creating an effective partnership. A KOL is typically...

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Sep 13, 2019

Medical and pharmaceutical manufacturers must adhere to strict sanitation standards and prioritize the safety of the products they create, regardless of production volume or costs. The U.S. Food and Drug Administration (FDA) strictly regulates the design, construction, and operation of medical and p...

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Sep 12, 2019

This blog will give a brief insight into the discipline of medical writing, including the various types of writing and the skills deemed necessary by top medical writing companies. If you require high-quality scientific and medical writing services get in touch with Phil or Anna today - we are more ...

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Sep 09, 2019

Four years ago, when ViiV Healthcare commissioned an ethnographic research study to understand the impact of HIV on black men in Baltimore and Jackson, Mississippi, the pharmaceutical company came away with a set of complex findings. Cultural identity, contextual environment, social structures and l...

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Sep 03, 2019

The term “cosmeceutical” has become popular in recent years to describe a cosmetic product that claims medicinal benefits. While those in the cosmetic industry use the term to advertise the ingredients and benefits of their products, the FDA does not legally recognize the term. According...

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Aug 28, 2019

Patients who are receiving long-term anticoagulation and are due for surgery, or other invasive procedures, may need to have their anticoagulants stopped temporarily to allow the procedure to be performed safely. In some circumstances, interrupting anticoagulation for a defined period carries minima...

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Aug 26, 2019

When constructing a cleanroom, the first decision you’re faced with is whether to opt for traditional (civil) construction over modular panels. There are several important considerations you must factor before making this expensive investment.

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Aug 08, 2019

Pharmaceutical companies have traditionally kept their data close to the vest because collaborations side effects may include compromising intellectual property and losing the edge over competitors. But sharing data has major perks. The more data a pharma company has at its disposal, the better equi...

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Jul 22, 2019

On July 18, 2019, the Second Circuit issued a summary order in United States v. Shkreli (Jacobs, Livingston, Bianco) affirming the conviction and sentence of Martin Shkreli after his highly publicized 2017 trial in which he was convicted on two counts of securities fraud and one count of conspiracy ...

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Jul 21, 2019

Bayer AG is a German chemical and pharmaceutical company that was founded in 1863 by Friedrich Bayerand Johann Wescott in Barmen, Germany. The company is one of the largest producers of aspirin and enjoys selling variety of medications for diabetes, birth control and multivitamins. Although recently...

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Jul 09, 2019

In a recent panel discussion at the World Economic Forum’s Annual Meeting of the New Champions, held in Dalian, China, ethicists and biotech executives met to discuss a plan for the future of biotech. One of the issues discussed was whether the new big breakthrough in the industry, and the dom...

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Jul 09, 2019

The 2019 Uhlman’s Pharmazing Days were held in June at Uhlmann’s headquarters in Laupheim, Germany. Over 500 attendees visited, and over 20 exhibition partners showcased pharmaceutical packaging solutions that are integrated with Uhlmann’s systems. Uhlmann Pac-Systeme showed its pa...

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Jul 04, 2019

Hot melt extrusion is a manufacturing technique that was originally established in the early 1930s for use in the plastics and food industries but is now gaining popularity in the pharmaceutical industry as well. Around half of all plastics products are made using hot melt extrusion, which is the pr...

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Jul 02, 2019

The check was from Eagle Pharmaceutical Executive Vice President and Chief Compliance Officer Michael Cordera. The Booker campaign said Cordera listed his occupation as “attorney” for the donation. "[Booker’s] presidential campaign rejects these contributions too, and we caref...

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Jul 02, 2019

While cures may not currently be possible for many forms of cognitive illnesses, are there ways to treat people without the use of drugs? Some believe it is possible to help manage some of the challenging behaviors and symptoms with a number of drug-free treatment options, including holistic therapi...

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Jul 02, 2019

Premier subsidiary ProvideGx is now supplying cysteine hydrochloride injections to its member providers, the generic-drug division of the group purchasing and consulting organization announced Tuesday. ProvideGx teamed up with the manufacturer Exela Pharma Sciences to deliver the only Food and Drug ...

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Jun 17, 2019

Pharmaceutical research is data-intensive. It takes tremendous computational power to parse and analyze the requisite giant chunks of data. The cloud delivers that power and helps accelerate research processes and, ultimately, research findings. That’s why one pharmaceutical company was using ...

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Jun 17, 2019

VenatoRx Pharmaceuticals will present ten posters featuring its two development-stage products, cefepime/VNRX-5133 and ceftibuten/VNRX-7145, at ASM Microbe 2019 to be held June 20-24 in San Francisco, CA. VenatoRx will also present an overview if its antibacterial agents portfolio during the Pharma ...

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Jun 17, 2019

The established Pharmacia demonstrates a complete makeover in its new issue after signing with scientific publisher and technology provider Pensoft and its signature open-access platform. Launched by the Bulgarian Pharmaceutical Scientific Society in 1954, the open-access, peer-reviewed Pharmacia ha...

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May 15, 2019

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) and Kymera Therapeutics today announced that the two companies have entered into a four-year strategic research and development collaboration to advance small molecule protein degraders against multiple targets. The collaboration will leverage Kymera...

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May 07, 2019

It could be about an error you missed, a question you should have asked or an unexpectedly positive outcome to a interaction you will never forget — some patients teach a valuable lesson that endures for an entire professional career. The Pharmaceutical Journal is now accepting entries for its...

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May 06, 2019

Open indictment of genocide and other crimes committed by white collor scientists in collaboration with governmental, medical, military and pharmaceutical establishments against Africans On the 4th of July, what a remarkable date, 2011, it becomes known that more and more African leaders and militar...

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Apr 25, 2019

“This is the biggest change in pharmacy education and training since the profession moved in the mid-20th century from the apprenticeship route to become a degree-only profession,” says Marc Donovan, chief pharmacist at Boots. But the proposals from the General Pharmaceutical Council (GP...

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Apr 23, 2019

A smoking cessation expert and a pharmacist share their views on whether pharmacies should stock and recommend e-cigarettes to people who want to kick their tobacco habit. It’s been more than ten years since the UK’s public smoking ban pushed cigarette smokers out into the cold in 2007, ...

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Apr 22, 2019

To help power its artificial intelligence-based pathology services, PathAI has raised $60 million in venture capital funding, with plans to accelerate its R&D into new digital tools and medical devices for the diagnosis and classification of diseases like cancer. In addition, the Boston-based co...

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Apr 19, 2019

According to the FDA, in 2017, 80% of the active pharmaceutical ingredients used to make our medicines are imported. I can’t remember how many times I’ve read (and written) that over the past decade or so. Almost every time I read that particular statistic in the news, it’s often a...

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Apr 15, 2019

Technology is a transformative force, and there is currently no technology more transformative than AI. Because AI encompasses so many different fields -- from robotics to deep learning to self-driving cars -- it can be hard to quantify the exact impact it has had on the economy and on individual in...

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Apr 15, 2019

The Government wants the UK to become a leader in the development of products which tackle the global challenge of antimicrobial resistance (AMR). Despite the renewal of the 5-year AMR Strategy, there is no time to wait before driving new antimicrobial innovations into the mainstream. There must be ...

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Apr 15, 2019

Specialist process machinery manufacturer, L.B. Bohle, has developed a cleaning system for the pharmaceutical industry using Bürkert's innovative FloWave flowmeter for a compact, hygienic and very accurate process. Incorporating the latest in flow measurement technology has minimised equipm...

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Apr 12, 2019

Hop on a Metro-North out of New York City on the New Haven Line. Soon, you’ll hit the pristine picket fences and well-manicured mansions of Fairfield County — the wealthiest metropolitan area in the nation, where finance and industry titans rake in million-dollar incomes and send their c...

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Apr 12, 2019

TALLAHASSEE, Fla. (AP) — Floridians could eventually gain access to cheaper Canadian prescription drugs under legislation passed Thursday by the state House, a top priority of Republican Gov. Ron DeSantis. The GOP-led House voted 93-22 on Thursday for the measure, which if finalized creates a ...

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Apr 04, 2019

The pharmaceutical industry spends billions on R&D each year. Clinical trials require tremendous amounts of effort, from identifying sites and enrolling patients to overseeing research functions and coordinating trial logistics. Trials often run over budget or are delayed because of a number of ...

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Apr 01, 2019

Researchers from the University of Michigan have developed and are now testing a device they call "the epitome of precision medicine" that detects cancer in circulating blood. "Nobody wants to have a biopsy," says Dr. Daniel Hayes, the Stuart B. Padnos, Professor of Breast Cancer...

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Mar 29, 2019

Dementia — an umbrella term for various neurodegenerative conditions involving memory loss and other forms of cognitive impairment — is hard to treat because its causes remain unknown. Researchers, however, are making painstaking progress. Dr. Kenneth Kosik, the Harriman Professor of Neu...

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Mar 28, 2019

Using artificial intelligence in drug design would give pharmaceutical research a boost, says Gisbert Schneider. In the medium term, computers could even carry out experiments autonomously. Designing drugs is a complex and challenging task. How do you create effective new medicines without adverse s...

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Mar 28, 2019

Accenture reports that in 2017, the 16 top biopharmaceutical companies in the world had an aggregate global revenue of $428 billion, which was nearly half the global pharmaceutical market by net sales. The report also revealed a shift to specialty drugs for hard-to-treat diseases. AI has numerous ap...

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Mar 28, 2019

The blood-brain barrier is a protective layer that surrounds the brain. Its main function is to prevent potentially harmful agents from leaking into this organ. However, it can also stop certain therapeutic drugs from reaching their target.The blood-brain barrier prevents antitumor drugs and those t...

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Mar 27, 2019

Research has revealed a biological explanation for why some people with depression do not respond to a class of antidepressants that doctors commonly prescribe. It has to do with fundamental differences in the nerve cells that produce and use serotonin.

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Mar 27, 2019

A randomized controlled study finds that a diet low in carbs can relieve pain for people who have knee osteoarthritis. Osteoarthritis is the most widespread form of arthritis among older adults in the United States. Knee osteoarthritis, in particular, affects about 10 percent of men and 13 percent o...

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Mar 26, 2019

Billions worldwide are infected with tropical worms. Unsurprisingly, most of these people live in poor countries, kept poor by the effects of worm-related malnourishment. What may surprise many is that worms also cause the majority of cases of some cancers in these countries. Published in Frontiers ...

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Mar 26, 2019

Five seconds is enough to assess the status of a hockey player’s groin. For the first time, a simple field test called the five-second squeeze test, has been used on ice-hockey players to see if it can indicate current hip/groin function and hip muscle strength. According to the new study from...

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Mar 26, 2019

In recent years, the ketogenic diet has become increasingly popular with people who want to lose weight quickly. A new study asks whether this dietary pattern works as well in females as it does in males. Experts originally designed the ketogenic diet, which people often refer to as the keto diet, a...

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Mar 26, 2019

Researchers have found that the dust in our households may harbor numerous chemicals that may accelerate the development of fat cells, potentially contributing to obesity.In recent years, researchers and international policymakers have expressed concerns about the effects of endocrine-disrupting che...

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Mar 26, 2019

Smoking is bad for the health of the smoker as well as those surrounding him. The cigarette is said to have over 600 ingredients in them which includes harmful substances such as carbon monoxide, formaldehyde, lead, acetone, and tar, etc. Since smoking is known to cause serious health ailments like ...

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Mar 26, 2019

India is historically a malaria endemic country. It holds the distinction of being the site of the discovery by Noble Prize winner Sir Ronal Ross that established the malaria parasite cycle through Anopheles mosquitoes as the definitive host, and the spectacular success of malaria control during the...

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Mar 25, 2019

In an Internet of Things (IoT) world, objects – from doorknobs to pill capsules – have computerized eyes and brains which can talk to each other and to us. That might sound like the beginning of a sci-fi horror story, but what it actually means is that there are more sources of useful in...

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Mar 25, 2019

It's not often that veterinary research is so controversial that it falls into the jaws of censorship zealots. That is exactly what happened recently, however, when editors at a science journal suddenly turned on a small Spanish sheep study which they had already peer-reviewed and published and ...

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Mar 25, 2019

The researchers – from Oxford's Nuffield Department of Clinical Neurosciences - conducted a clinical trial with 156 elderly patients who had mild cognitive impairment and a high risk of dementia and Alzheimer's disease. The researchers randomized the patients and for two years, gave on...

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Mar 25, 2019

A new study on the effects of vitamin D found that too much may lead to slower reaction times and increase the risk of falling among older people. Vitamin D is an essential vitamin that helps build and maintain healthy bones and teeth. Without this, our bodies cannot absorb calcium, which is the mai...

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Mar 25, 2019

Sadly, preterm death is one of the leading causes of death among children under five years of age. To develop a solution, it is imperative that scientists can measure the extent of the issue at a population level across the globe. In underdeveloped countries where pregnant women do not have routine ...

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Mar 25, 2019

The ketogenic diet recently has been touted for weight loss and improving blood sugar control, but a new study finds that females fail to show these metabolic benefits on this high-fat, very low-carbohydrate diet. Results of the animal study will be presented Sunday, March 24 at the Endocrine Societ...

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Mar 24, 2019

Are memory loss and decreased brain power inevitable as we age? Many people in their 40s, 50s and beyond are told that it is and there is nothing that can be done about it. Is that true? Of course, not Steps can be taken to not only stop memory loss but also reverse it. Here is a simple step. New re...

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Mar 24, 2019

Researchers say a drug that is already available on the market can help those affected by cystic fibrosis.Amphotericin, which is an antifungal medication, might help people with cystic fibrosis fight the chronic bacterial lung infections that tend to occur with this disease, according to a recent st...

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Mar 23, 2019

The authors of a new study conclude that healthful food prescriptions in Medicare and Medicaid would be more cost-effective after 5 years than preventive drug treatments. Medicare and Medicaid are the two largest healthcare programs in the United States. Approximately 57 million people received cove...

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Mar 22, 2019

Cutaneous leishmaniasis (CL) remains one of the most neglected of the neglected tropical diseases or NTDs. CL is caused by infection with the protozoan parasite Leishmania which is spread by the bite of an infected sand fly and resides inside human macrophages.

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Mar 22, 2019

The growing market for biopharmaceuticals1 brings new challenges for drug developers and manufacturers in assuring product quality and safety, and much of this can be attributed to product variability caused by post-translational modifications (PTMs).

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Mar 21, 2019

Despite the nature of this event, there is still a great deal of uncertainty around how it will happen, when and if indeed it will happen at all. Add to this that there is still no real clarity on the consequences of Brexit if and when it happens not for the public, not for businesses, and certainly...

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Mar 21, 2019

If you’ve spoken with your doctor about protecting your heart health, you likely received advice about eating well and starting an exercise routine. But a recent study suggests there’s another way to help: get a good night’s sleep. Previous research has suggested a link between poo...

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Mar 21, 2019

University of Otago scientists have discovered a way to view the immune cell ‘landscape’ of bowel cancer tumors, paving the way towards more individualized medicine and treatment for many other diseases in the future. The scientists have shown the incredible diversity of immune cells tha...

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Mar 20, 2019

Data drives drug discovery, yet it continues to be among the biggest challenges faced by the industry. Experiments are often not repeatable and data interpretation is subject to the biases and limitations of human beings.There are many reasons that molecules fail to become marketed drugs. In order t...

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Mar 20, 2019

A skin swab test for Parkinson's has become a real possibility after mass spectrometry was used to detect altered levels of specific compounds on the skin of people with the condition. The research is a result of the incredible ability of one woman to detect a unique odor on the skin of people w...

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Mar 20, 2019

Using strong and targeted but noninvasive magnets at specific sites in the brains of people with and without mild learning and memory problems, Johns Hopkins researchers report they were able to detect differences in the concentrations of brain chemicals that transmit messages between neurons. The s...

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Mar 20, 2019

New research suggests that adults over the age of 40 who engage in leisurely physical activity such as dancing, gardening, or going for a walk for even a short amount of time each week may have a lower risk of death from multiple causes.Previous research has shown that engaging even in low-level phy...

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Mar 20, 2019

After transforming the face of Marketing, Sales, and Service, Big Data is extending its reach and impact into other industries. While industries such as Automation, Oil and Gas, Metallurgy, Military, Education, and Hospitality have been faster than the rest in adopting and promoting Big Data applica...

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Mar 19, 2019

Artificial intelligence (AI) has turned into a great tool for the pharma industry. It’s helping with drug discovery, rare disease detection, high-quality analytics, clinical trial patient enrollment, personalized patient care and more. According to Statista, artificial intelligence revenue fro...

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Mar 19, 2019

Rare diseases do not always lead to restricted and shorter life spans. Sometimes they can actually help improve survival. Not everyone suffering from a rare disease faces a debilitated or shorter life. Consider Gilbert syndrome (GS), a hereditary condition that is usually mild and, ironically, a pro...

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Mar 19, 2019

Using nanotechnology, UCF researchers have developed the first rapid detector for dopamine, a chemical that is believed to play a role in various diseases such as Parkinson's, depression and some cancers. Studies show too much dopamine could be associated with some cancers, while low dopamine co...

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Mar 19, 2019

As continuous flow technology takes center stage, we are seeing a transformation in chemical production. To learn more about the transition away from batch-wise approaches to chemical reactions, the advantages, and challenges of using flow technology, and how its adoption has impacted the industry w...

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Mar 19, 2019

A red spot on the eye may look worrying, but it is rarely a medical emergency. Usually, a red spot on the eye occurs when blood collects under the conjunctiva due to a subconjunctival hemorrhage. The conjunctiva is the transparent membrane that covers the surface of the eye. The conjunctiva contains...

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Mar 19, 2019

New research in mice reveals that an innovative light and sound stimulation therapy can clear toxic plaque buildup in the brain and reduce some of the symptoms of Alzheimer's disease and impaired cognitive functioning.The hallmarks of Alzheimer's disease in the brain include the formation of...

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Mar 19, 2019

Researchers already recognized the link between depression and heart disease. However, until recently, the mechanisms explaining it remained a mystery. A new study reveals that stress-induced inflammation may explain why mental and cardiovascular health is so intimately related.

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Mar 19, 2019

Scientists have cracked a cell mechanism that drives tumor formation in most types of cancer. This finding could lead to much-needed new therapies for cancer, including the hard-to-treat triple-negative breast cancer.The discovery concerns the molecular activity of the tumor suppressor protein p53. ...

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Mar 19, 2019

New cardiovascular disease prevention guidelines submitted jointly by the American College of Cardiology and the American Heart Associated and published in the Journal of the American College of Cardiology contradict decades of routine medical advice by explicitly advising against the daily use of l...

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Mar 19, 2019

Cell line development is a major step for examining the efficiency of drug discovery, toxicity, and in-vitro testing. It reduces time, effort and cost, which minimizes the chance of research drugs failing at the clinical trial stage. This stage involves the production of recombinant proteins such as...

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Mar 19, 2019

In a new study from the Intermountain Healthcare Heart Institute in Salt Lake City, researchers have identified eight new gene mutations that may cause or contribute to idiopathic dilated cardiomyopathy, a form of heart disease not caused by known external influences, such as high blood pressure, ob...

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Mar 19, 2019

African refugee women experience healthier pregnancies than women born in the United States, despite receiving less prenatal care, found a recent University at Buffalo study. Compared to U.S.-born black and white women, African refugee women had fewer pre-pregnancy health risks, fewer preterm births...

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Mar 19, 2019

Common medications prescribed to treat heartburn, acid reflux and ulcers are linked to increased risks for kidney failure and chronic kidney disease, found a recent University at Buffalo study. Use of proton pump inhibitors (PPI), a group of drugs that reduce the production of stomach acid, increase...

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Mar 19, 2019

New research, published in the journal Applied Ergonomics, reviews the health benefits of sit-stand desks. Heart disease, cancer, type 2 diabetes, obesity, and premature death are only some of the adverse effects associated with a sedentary lifestyle. A recent study found that excessive sitting may ...

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Mar 19, 2019

Tuberculosis is one of the world’s deadliest infectious diseases: One-third of the world’s population is infected with TB, and more than 1 million people die from the disease every year. One reason TB is so pervasive is that treatment requires a six-month course of daily antibiotics, whi...

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Mar 18, 2019

Over the last few years, Artificial Intelligence and Machine learning have become widely discussed topics in the area of pharmaceuticals, healthcare and life sciences. A lot of pharmaceuticals companies and healthcare organizations express significant interests in possible new opportunities associat...

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Mar 18, 2019

As a procurement planner in the competitive life sciences sector, how do you ensure your organization adapts swiftly to the rapidly changing demands of customers and stakeholders? Whether supporting a CRO, pharmaceutical company, clinical lab, biotech business or academic department, procurement tea...

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Mar 18, 2019

Artificial intelligence (AI) is a hot topic in the research world, and for good reason. The promises made by AI optimists are exciting, from AI drug discovery to robot doctors as good as any human physician. AI pessimists are quick to point out that we have a long, maybe impossibly long, way to go b...

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Mar 18, 2019

Regulation of emerging technology such as genome editing has mainly focused on responding to the consequences of innovation. The classical regulatory model of “identification-quantification-assessment-safety management” takes a risk-oriented approach to regulation of emerging technology ...

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Mar 18, 2019

Following a series of experiments, researchers conclude that two compounds found in coffee might help slow the growth of prostate cancer cells. Although the findings are preliminary, they are encouraging. Coffee is one of the most popular drinks on the planet and is a complex cocktail. In fact, coff...

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Mar 18, 2019

A recent study has linked higher consumption of eggs or dietary cholesterol to a higher risk of cardiovascular disease and premature death. The finding is likely to rekindle the debate on eggs and heart health.For example, the new study seems to contradict the decision in the United States to omit s...

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Mar 18, 2019

In the future, a doctor might be able to tell whether someone is heading toward Alzheimer's disease not by carrying out expensive brain scans, but during an eye exam. A new study paper in the journal Ophthalmology Retina outlines research that took place at Duke Eye Center in Durham, NC. The res...

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Mar 18, 2019

A preliminary study concludes that a drug that doctors commonly prescribe to treat angina and blood pressure might increase the risk of sudden cardiac arrest.Cardiac arrest occurs when the heart stops pumping blood around the body. If a person does not receive treatment, cardiac arrest can be lethal...

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Mar 18, 2019

New research finds an accurate way of diagnosing fibromyalgia and differentiating it from other related conditions. Using blood samples and innovative techniques, scientists have detected a "molecular fingerprint" that is unique to the condition.Fibromyalgia is a chronic condition that aff...

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Mar 18, 2019

For many years, members of the Dutch Consortium for Healthcare Evaluation and Research in Obstetrics and Gynecology (NVOG Consortium) have been working on the improvement of care for patients with threatened preterm birth. One of the research topics, the safety, and effectiveness of labor-suppressin...

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Mar 18, 2019

Carbon black nanoparticles are manufactured for use in rubber products, as a color pigment in plastics, paint, and ink and used to model exposure to air pollution particles. These particles have been shown to have toxic effects and previous mice studies have shown that maternal exposure can affect t...

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Mar 17, 2019

According to a small pilot study, moisturizing our skin might reduce the risk of developing a range of chronic conditions, including heart disease, diabetes, and even Alzheimer's disease. The skin is our largest organ. One of its primary functions, of course, is to protect our insides from the d...

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Mar 17, 2019

The American Society of Plastic Surgeons has published new statistics that reveal recent trends in body-shaping procedures.According to the American Society of Plastic Surgeons (ASPS), almost 18 million people underwent surgical and minimally invasive cosmetic procedures in the United States in 2018...

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Mar 16, 2019

The "first" genomics era began with the landmark Human Genome Project, which launched in 1990 and was completed in 2003, leading to the sequencing of the 20,000-25,000 human genes. It gave birth to an omics revolution and, by necessity, a series of increasingly sophisticated technologies a...

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Mar 15, 2019

By exposing mice to a unique combination of light and sound, MIT neuroscientists have shown that they can improve cognitive and memory impairments similar to those seen in Alzheimer’s patients. This noninvasive treatment, which works by inducing brain waves known as gamma oscillations, also gr...

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Mar 15, 2019

Green tea cut obesity and a number of inflammatory biomarkers linked with poor health in a new study. Mice fed a diet of 2 percent green tea extract fared far better than those that ate a diet without it, a finding that has prompted an upcoming study of green tea’s potential benefits in people...

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Mar 15, 2019

Did you wake up bright and bushy-tailed this World Sleep Day? Or did you throw your slippers at your 6.30AM alarm and then fall back asleep whilst having a shower? If the latter option seems more familiar, you might consider yourself a night owl. New research from the University of Birmingham explai...

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Mar 15, 2019

New research, published in the journal Science Signaling, details the mechanism through which exposure to manganese can trigger protein misfolding in the brain which may, in turn, lead to Parkinson's-like symptoms. The findings may enable an earlier diagnosis of the neurological condition.

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Mar 14, 2019

Undernutrition contributes to almost half of all deaths in children under the age of five. (WHO) Agilent is helping to counteract this in a highly innovative way. The World Health Organization recommends to exclusively breastfeed babies from birth to six months of age. (WHO). This would provide youn...

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Mar 14, 2019

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the US, with approximately 16 million Americans currently affected. Researchers at the University of Michigan have reported on the ability of Parametric Response Mapping (PRM), a relatively new technique, to identif...

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Mar 14, 2019

New research in mice identifies a compound that prevents ovarian cancer recurrence by eradicating the cancer stem-like cells that conventional chemotherapy leaves behind.According to the National Cancer Institute, there were over 22,000 new cases of ovarian cancer in the United States in 2018. More ...

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Mar 14, 2019

Breakthrough research has yielded a cluster of genetic markers that could form the basis of a blood test for PTSD. Scientists at the Indiana University School of Medicine in Indianapolis suggest that their findings could lead to more accurate diagnoses of post-traumatic stress disorder (PTSD). "...

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Mar 13, 2019

How the cloud in particular stands to shift the pharmaceutical industry and why these changes are so important for its future. The speed of cloud adoption has varied across industries, and whilst financial services and manufacturing are still lagging, healthcare and pharmaceuticals, after years of r...

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Mar 13, 2019

We’ve spoken to many leaders in healthcare and pharma over the last half a decade, and when it comes to AI, the most pressing challenge that healthcare and pharma leaders report is that they’re unsure of how to streamline and structure their data in a way that lets them build machine lea...

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Mar 13, 2019

Automated lab analytics solutions are increasingly taking to the cloud to give labs real-time visibility of instrument and consumables usage. This is valuable information – for example to understand what throughput is available to scale up and complete programs in weeks and hours rather than m...

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Mar 13, 2019

Autism doesn’t just affect boys and men, but research on the condition still predominantly focuses on them. Some scientists are finally beginning to include women and nonbinary people in their studies.

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Mar 13, 2019

What do people fear the most about getting old? The answer is Alzheimer’s disease. Indeed, a 2014 poll conducted in the United Kingdom found that two-thirds of people over the age of 50 were worried about developing dementia, which primarily manifests in the form of Alzheimer’s disease, ...

article

Mar 13, 2019

A midday nap may be just what you need, not just to boost your energy levels but also to lower high blood pressure. This, at least, is what new research from Greece suggests.When the afternoon slump hits in the middle of a busy workday, many of us may feel tempted to catch some shut-eye in a quiet c...

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Mar 12, 2019

Next-generation sequencing (NGS) is helping to advance genomics research at an unprecedented rate. However, the process can be technically challenging, and any errors can significantly impact the reliability and accuracy of your results. NGS library preparation and QC can have a major impact on your...

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Mar 12, 2019

Basil seeds aren’t just for growing basil plants you can also eat them. They look similar to sesame seeds but are black. The type that you eat typically comes from sweet basil, Ocimum basilicum, which is the plant commonly used to season foods. For this reason, the seeds are typically referred...

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Mar 12, 2019

An antibody that blocks the action of a hidden viral protein encoded by our genome shows encouraging signs of slowing down the progression of multiple sclerosis, according to the Swiss biotech GeNeuro which carried out the research. GeNeuro’s monoclonal antibody drug targets the hidden viral p...

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Mar 12, 2019

Scientists from the Netherlands have received a €600,000 grant to test a treatment for osteoarthritis in humans that combines hydrogels and stem cells to help the knee joint heal. In osteoarthritis, the cartilage in joints such as the knees breaks down, causing stiffness and pain. There is no c...

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Mar 12, 2019

New research, published in the Journal of the American College of Nutrition, finds that adhering to the Mediterranean diet for just 4 days is enough to boost exercise performance.The Mediterranean diet offers a range of benefits, from cardioprotective effects to staving off chronic disease. As a res...

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Mar 12, 2019

When we sleep poorly, we may feel less inclined to participate in social activities. Now, researchers have found evidence that being sleep-deprived can not only make us less sociable, but it can also prevent our peers from seeking us out.Sleep deprivation can contribute to a host of mental and physi...

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Mar 11, 2019

For decades, Piri Welcsh has had professional and personal stakes in understanding the genetics of breast cancer. In the 1990s, the molecular geneticist participated in an international race to clone BRCA1, the first gene linked to breast cancer risk, and she works to this day in the lab of pioneeri...

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Mar 11, 2019

New research uncovers a host of vascular risk factors that may affect the health of our brains as we get older.It is no secret that the global population is aging at an increasingly fast pace. According to the World Health Organization (WHO), there were approximately 900 million people across the gl...

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Mar 11, 2019

Many pregnant women take vitamin B-6 and Unisom to treat morning sickness. In the past, some people had concerns that this combination may harm the fetus. Morning sickness is very common during early pregnancy. Although people often refer to nausea and vomiting during pregnancy as "morning sick...

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Mar 11, 2019

Many people worldwide have type 2 diabetes, a metabolic condition in which the body cannot properly regulate blood sugar levels. Experts already know that lack of physical activity can contribute to the risk of diabetes, but what type of exercise might lower it?Recently, researchers have been lookin...

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Mar 11, 2019

The lemon detox diet involves consuming just a lemon juice-based mixture for 1 or 2 weeks, with no solid foods. The diet aims to remove toxins and cleanse the body. However, scientists have found no evidence to support these claims, and the diet may be harmful in some cases.

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Mar 11, 2019

An experimental drug has shown great promise in limiting the damage that a heart attack can inflict on the heart. It targets a protein that plays a central role in the death of heart muscle cells.Tests on mice have revealed that the drug could markedly reduce heart injury from a heart attack.

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Mar 11, 2019

New advances in diabetes research are making it possible to develop a fully automated insulin delivery system that can control blood sugar without any input from the patient. This so-called artificial pancreas could be here within the next decade, but there are still three main challenges that scien...

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Mar 11, 2019

When we listen to loud sounds, like at a music concert, our hearing may become impaired for a short time. Researchers at Linköping University have discovered a mechanism that helps to explain how this happens. “Most people have experienced that their hearing is impaired and the ear feels ...

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Mar 11, 2019

Each year there are nearly 11 million cases of typhoid, a disease that is spread through contaminated food, drink, and water. Researchers at the University of Maryland School of Medicine are leading an international consortium that is studying the impact of a typhoid conjugate vaccine (TCV) in an ef...

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Mar 11, 2019

New research indicates that colorectal cancer diagnosed at an early age has clinical and genetic features that are different from those seen in traditional colorectal cancer diagnosed later in life. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study a...

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Mar 11, 2019

Standard tests used to identify dehydration are not working for older people living in care homes – according to new research from the University of East Anglia. Carers often use simple tests to see if an older person is dehydrated. These include looking at their eyes, skin, or asking if someo...

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Mar 11, 2019

Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients benefit from immunotherapy, a new study reveals. Scientists found that PARP inhibitors sparked a powerful immune response when used against cancer cells with ...

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Mar 08, 2019

The health effects of fat and carbs are controversial. However, almost everyone agrees that protein is important. Most people eat enough protein to prevent deficiency, but some individuals would do better with much higher protein intake. Numerous studies suggest that a high-protein diet has major be...

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Mar 08, 2019

There are two main culprits that accelerate the aging process of our skin: sun exposure and advanced glycation end products (AGEs). AGEs form when protein or fat combine with sugar. While these aging culprits aren’t 100 percent in our control, using sunscreen and taking mind of your overall di...

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Mar 08, 2019

The challenges of parenthood for working parents are well known and, in STEM (Science, Technology, Math and Engineering) fields, have been strongly linked to the “leaky pipeline” the loss of women from scientific careers at much higher rates than men. In contrast, the challenges that man...

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Mar 08, 2019

Living a healthy and happy life needs work on your part. You can’t spend all your day playing video games or lying down in the bed and then expecting good health for life. That is unrealistic! What is realistic though is to get up early, do your yoga and make habits that contribute to a health...

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Mar 08, 2019

PCOS or Polycystic ovary syndrome happens due to hormonal imbalance in women. PCOS can start as early as the teens. It is marked by excessive levels of androgens or male hormones in the body. The exact cause of PCOS still remains uncertain. Its symptoms begin to show slowly.

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Mar 08, 2019

March is Colorectal Cancer Awareness Month. Colorectal cancer (CRC), also known as bowel cancer, is the second highest cause of death in Europe. Although we are now better at diagnosing the disease at an earlier stage through the bowel screening program and have made improvements in surgical methods...

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Mar 08, 2019

The Food and Drug Administration wants the pharmaceutical industry to get away from making drugs using the traditional batch method and switch to a more modern process known as continuous manufacturing. The FDA put out a statement on Feb. 26 saying the continuous process allows manufacturers to more...

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Mar 08, 2019

New research that now appears in the British Journal of Cancer suggests that a person's history of mental health issues may raise their risk of dying from cancer following diagnosis.Though the cancer mortality rates in the United States have "declined steadily" during the past 20 years...

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Mar 08, 2019

Today, millions of people in the United States are unaware that they have diabetes. A recent study finds that data from a readily available smartphone app could help detect diabetes in people without requiring a trip to the clinic.

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Mar 08, 2019

Happy International Women's Day! This date has its origins back in the early 1900s when women were marching for voting rights and better working rights. In 1909, the first National Women's Day was observed in the U.S. From that point on, more countries began to observe the day and it was off...

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Mar 07, 2019

If you’ve decided you need to incorporate phenotypic screening into your discovery program and you know that one of the new generations of automation platforms is the way forward, what factors should influence your choice?

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Mar 07, 2019

Pathology studies the causes and effects of cancer and other diseases. Pathologists work by examining tissue samples in a laboratory. But with the advent of personalized medicine, the pathologist’s role is profoundly changing.Traditionally, pathologists were viewed as “diagnosticians wor...

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Mar 07, 2019

Enterovirus-A71 (EV-A71), a member of the genus Enterovirus in the Picornaviridae family1, is one of the most common causes of hand, foot, and mouth disease (HFMD) in younger children and occasionally causes large-scale epidemics worldwide, especially within the Asia-Pacific region. In addition, EV-...

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Mar 07, 2019

With more than 100 confirmed cases of measles in the United States already this year, vaccines are once again squarely at the center of passionate national debate. At the heart of the issue are the concerns of parents about the safety of vaccines for their children. These concerns are pitted against...

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Mar 07, 2019

A new large-scale Danish study searches for connections between autism and the MMR vaccine. In particular, they investigate at-risk individuals. Once again, no links are found.The furor surrounding vaccines and their relationship with autism have been rumbling along for decades.

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Mar 07, 2019

Sleep is an important part of the daily life cycle of most animals including humans. But when an animal sleeps, it leaves itself defenseless in the face of danger. So, what makes sleeping so important that we all take this risk?Research, both old and new, acknowledges that sleep plays an important r...

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Mar 07, 2019

Genes may have a discernible impact on the quality of a marriage, according to a recent study of couples in their middle and later years.Researchers at the Yale School of Public Health, New Haven, CT, investigated how a gene variant that influences the so-called love hormone oxytocin might contribut...

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Mar 07, 2019

Small molecule drug discovery has long been the domain of pharmaceutical companies, and that’s not likely to change anytime soon. But there’s a cadre of universities and nonprofit research institutes that have embraced drug development at its earliest stages, in some cases identifying an...

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Mar 07, 2019

Colon cleansing is also termed as colonics or colonic irrigation. It is the procedure done to remove toxins and other waste products from your colon by administering a large amount of water or any other fluids or laxatives or by administration of purgatives orally or dietary fibers. There are variou...

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Mar 06, 2019

Natural language processing (NLP) seems to see less use in pharma than AI approaches such as machine vision and predictive analytics, but nevertheless there are a few applications for NLP in pharma. The industry deals mostly with structured data, but in some business areas, unstructured data is the ...

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Mar 06, 2019

A large-scale study of half a million people over 10 years confirms yet again that there is no connection between the measles, mumps, rubella (MMR) vaccine, and autism. No link has been found between the measles, mumps, rubella (MMR) vaccine, and autism in largest, single study to date. Researchers ...

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Mar 06, 2019

New research reveals that being overweight, obese, or severely obese may improve a person's chances of surviving after a stroke. Obesity is a "serious medical condition" that can lead to various complications. These might include atherosclerosis and heart disease, diabetes, cancer, and...

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Mar 06, 2019

Research has linked a particular sleep disorder called rapid eye movement (REM) sleep behavior disorder with a diagnosis of Parkinson's disease. What characterizes this sleep problem, and can its presence be a good way to predict Parkinson's risk?Data from the National Institutes of Health (...

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Mar 05, 2019

Are you guilty of making decisions without the data to back them up? In today’s busy labs, mission-critical decisions about laboratory equipment purchases, service contract renewals, consumables spending, and staffing are often made on the basis of incomplete information. Having a clear pictur...

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Mar 05, 2019

A few decades ago, an important finding caused a paradigm shift in cancer genetics. Studies reported that key events in cancer initiation and progression can occur regardless of the underlying DNA. A field then emerged to curb cancer via epigenetics, the study of heritable changes in gene expression...

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Mar 05, 2019

Daylight saving time can bring a welcome end to the short, dark days of winter, but it can also disrupt our natural sleep cycles. If parents fail to plan ahead, the consequence is short-term sleep deprivation for their children and teens. This can cause temporary irritability and behavioral issues i...

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Mar 05, 2019

A new intervention helps people lose weight and improve their depression symptoms at the same time. Millions of Americans have been diagnosed with depression. Even more, have obesity. For many people, these conditions go hand in hand, increasing their risk for other health conditions and decreasing ...

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Mar 05, 2019

Medication management is the process of overseeing the medications prescribed for a patient to ensure they are taken properly and achieving their planned, therapeutic outcome. The process includes initial and ongoing medication review to address safety and adherence concerns, reduce adverse drug eve...

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Mar 05, 2019

Acute renal failure is when a person's kidneys are not working as well as they once did. This usually happens very suddenly over several hours or up to 2 days. Many people do not experience symptoms until their condition has advanced. As a result of acute renal failure (ARF), the kidneys do not ...

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Mar 05, 2019

Experts have already concluded that exercise can help people with Parkinson's disease improve their motor symptoms, but what is its effect on the cognitive symptoms of this condition?Parkinson's disease is a neurological condition that usually stands out for the motor symptoms that it causes...

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Mar 05, 2019

Crohn's disease is a lifelong condition that causes inflammation and irritation along the digestive tract. Knowing the facts about Crohn's can help a person better understand and manage their condition. In this article, we explore Crohn's disease and its causes, risk factors, and prevale...

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Mar 05, 2019

It may be feasible to treat pancreatic cancer by using one drug to get the cancer cells to depend on a single source of energy, and another drug to take it away from them. The approach looks promising after a recent study successfully tested it on pancreatic cancer cells and mice in the laboratory. ...

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Mar 05, 2019

New research, published in the journal Frontiers in Cellular and Infection Microbiology, shows that an antiseptic compound found in mouthwash destroys "friendly" oral bacteria that help maintain normal blood pressure levels.Scientists know that the bacteria in our guts influence overall he...

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Mar 05, 2019

Drug repurposing can often reduce the time and cost it takes to discover and develop a new drug, especially for novel antimicrobial therapies. Helicobacter pylori is a Gram-negative, helically shaped, stomach pathogen associated with human gastric mucosa. After entering the body, they can cause chro...

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Mar 05, 2019

Every day our kidneys tackle the daunting task of continuously cleaning our blood to prevent waste, salt, and excess fluid from building up inside our bodies. To achieve this, the kidneys’ approximately one million filtration units (glomeruli) first remove both waste products and precious nutr...

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Mar 05, 2019

Assessing the patterns of energy use and neuronal activity simultaneously in the human brain improves our understanding of how alcohol affects the brain, according to new research by scientists at the National Institutes of Health. The new approach for characterizing brain energetic patterns could a...

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Mar 05, 2019

Not every embryo contains 46 perfect chromosomes. Some have more, others have fewer. The result is a common abnormality known as aneuploidy, which occurs in as many as 80 percents of human embryos. Because aneuploidy has been linked to a risk of in vitro fertilization failure, miscarriage, and certa...

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Mar 05, 2019

Scientists have shown for the first time that the brain is involved in the development of a heart condition called Takotsubo syndrome (TTS). They found that regions of the brain responsible for processing emotions and controlling the unconscious workings of the body, such as heartbeat, breathing, an...

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Mar 05, 2019

In autoimmune diseases, such as type 1 diabetes and multiple sclerosis, the body's immune system mistakenly attacks healthy cells, believing them to be harmful agents. Recently, scientists have been conducting new research with the aim of devising an innovative strategy to treat these conditions...

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Mar 05, 2019

People who suffer from stress-related Irritable Bowel Syndrome have a distinctive microbial signature in their gut. However, holistic, psychosomatic therapy using hypnosis is significantly more effective at treating their condition than symptomatic or probiotic treatment alone. This is the finding o...

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Mar 05, 2019

New research, which features in the Journal of Neurology, Neurosurgery & Psychiatry, finds that having a cocoa drink every day for 6 weeks helps combat fatigue in people living with multiple sclerosis.Multiple sclerosis (MS) is an autoimmune disorder that affects about 400,000 people in the Unit...

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Mar 05, 2019

Even among cancers, pancreatic cancer is an especially sinister form of the disease. The one-year survival rate is extremely low, and treatment progress has lagged behind that of many other malignancies. A study published today in the journal Nature Medicine led by researchers at Huntsman Cancer Ins...

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Mar 04, 2019

In response to the rapidly growing influence of managed care, the pharma industry has undergone significant transformation. In the past, to drive prescriptions, the main focus of pharma companies was selling to the individual doctors. Under the traditional fee-for-service model, physicians based the...

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Mar 04, 2019

Artificial intelligence in Pharma refers to the use of automated algorithms to perform tasks which traditionally rely on human intelligence. Over the last five years, the use of artificial intelligence in the pharma and biotech industry has redefined how scientists develop new drugs, tackle disease,...

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Mar 04, 2019

Just about all of us have experienced a bloated belly. But for some people, bloating causes near daily distress. I hear from people all the time who suffer from bloating and want to know what they should be eating or not eating to avoid it. And of course, you’ll see magazine and internet artic...

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Mar 04, 2019

For years, BIO has been urging both state and federal policymakers to adopt responsible solutions that would make prescription drugs more affordable for America’s patients. At times, our advocacy work includes the need to raise concerns with some of the policy proposals being discussed. That&r...

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Mar 04, 2019

Going bald may seem to be a fact of life for many men and women as they age, but there are new treatments that could make a difference. While there have been some longtime recommended treatments for hereditary hair loss like Rogaine and Propecia, there haven’t been any major breakthroughs in r...

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Mar 04, 2019

Whenever we sleep poorly throughout the week, we comfort ourselves with the thought that we will make up for lost slumber at the weekend. However, a new study brings us the bad news: sleeping in at the weekend does not reverse the damage of chronic sleep loss.

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Mar 04, 2019

Viruses are responsible for colds and flu, so antibiotics are not able to cure or prevent these illnesses. Plenty of rest, fluids, and home remedies can help relieve symptoms.Colds and the flu are common illnesses that can cause many uncomfortable symptoms, such as.

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Mar 04, 2019

How cells in developing embryos communicate depend a great deal on context, according to scientists at Rice University. They found that a protein signaling pathway is known as WNT and its interactions are far more dynamic than once thought as the response of different cell types to the same signals ...

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Mar 04, 2019

Genetic manipulation that more than doubles lifespan also leads to better offspring - according to new collaborative research from the University of East Anglia and Uppsala University. Researchers studied a gene, known as DAF-2, which is associated with aging in roundworms (Caenorhabditis elegans). ...

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Mar 04, 2019

Scientists at the cutting edge of nanotechnology are on the path to the seemingly impossible: creating an injection that allows us to see in the dark. This research opens the door to brand new therapeutic interventions. The mammalian eye can only respond to a small band of wavelengths. Generally, th...

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Mar 04, 2019

Many people consider logging everything that they eat to be a tedious task. However, this effective weight-loss technique takes much less time than most people think, according to a recent study. Obesity is now a common health issue. According to the Centers for Disease Control and Prevention (CDC),...

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Mar 04, 2019

New research by scientists at the University of Nottingham suggests that environmental contaminants found in the home and diet have the same adverse effects on male fertility in both humans and in domestic dogs. There has been increasing concern over declining human male fertility in recent decades ...

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Mar 04, 2019

Women who clock 55 working hours or more every week might have a higher risk of depression. Also, working weekends can increase depression risk for both men and women.A new study that now appears in the Journal of Epidemiology & Community Health found that working excessively long days could be ...

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Mar 03, 2019

Good health, unfortunately, is not experienced by every human being on earth. Be it a man or a woman and people of all ages do face some kind of health-related issue or contract disease at some point in time in their lives. The age of reasoning and modern science gave birth to conventional forms of ...

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Mar 02, 2019

Myasthenia gravis is an autoimmune disease with an estimated prevalence of 14-20/100,000 population in the U.S. and 1-9 /100,000 population in Europe. Many affected individuals go undiagnosed. Myasthenia gravis can cause severe muscle weakness and greatly impact the quality of life. Diagnosis can be...

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Mar 02, 2019

A lack of essential nutrients is known to contribute to the onset of poor mental health in people suffering from anxiety and depression, bipolar disorder, schizophrenia, and ADHD. Nutritional psychiatry is a growing discipline that focuses on the use of food and supplements to provide these essentia...

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Mar 02, 2019

Broken capillaries appear when the vein wall is too weak to withstand the pressure of the blood being pumped around the body. Reduced resistance of the vein walls is common in women during menopause, when broken capillaries in the arms and legs can mean reduced oestrogen levels (hormonal imbalance)....

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Mar 02, 2019

New research, appearing in the BMJ Journal of Neurology, suggests that various pollutants may not only raise the risk of people developing ALS but also make the disease advance faster.Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a neurodegenerative condition that a...

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Mar 02, 2019

Filled with empty calories and ultra-processed, fast food may increase the risk of obesity and cancer. While fast-food chains have ostensibly been trying to offer more healthful options, a new study finds that the health impact of their menus has not improved to the contrary, in fact.Data from the C...

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Mar 01, 2019

Yes! You can’t deny that infertility can be depressing and highly frustrating not only to the couple but also their families. If you have been lucky enough not to go through it, perhaps your family member or friend was. Believe me, after reading this, you will have a handful of helpful suggest...

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Mar 01, 2019

Today, the Opioid Detection Challenge, a $1.55 million USD global prize competition, was launched by the U.S. Department of Homeland Security (DHS) Science and Technology Directorate (S&T), in collaboration with U.S. Customs and Border Protection (CBP), the Office of National Drug Control Policy...

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Mar 01, 2019

The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant prostate cancer subtype called neuroendocrine prostate cancer (NEPC). No effective t...

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Mar 01, 2019

New research, appearing in the Journal of Physiology, suggests that short bursts of intense, physical activity may reduce the growth of colorectal tumor cells. According to the American Cancer Society, doctors will diagnose more than 100,000 new cases of colon cancer and in excess of 44,000 cases of...

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Mar 01, 2019

Brain tumors vary widely in how they respond to treatment. However, early assessment of therapy response is essential in order to choose the best possible treatment for the patient. Scientists from the German Cancer Research Center (DKFZ) have now been able to show in a study using non-invasive high...

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Mar 01, 2019

Older people who want to preserve their faculties may wish to consider rationing their TV time. A large new study of older adults found that those who spent at least 3.5 hours per day watching TV experienced a greater decline in verbal memory.Researchers at University College London in the United Ki...

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Mar 01, 2019

A recent study dives into the details of exactly how cells fix DNA mutations. The researchers provide fresh insight into so-called flawless DNA repair. Cancer research often involves a multi-pronged approach. Of course, testing new treatments and finding novel ways to attack tumors is paramount. At ...

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Mar 01, 2019

New research, appearing in the journal Cell, reveals a drug compound that could halt the growth of an aggressive form of melanoma.Melanoma is a type of skin cancer that accounts for 1 percent of all skin cancer cases. Despite this small percentage, melanoma is responsible for a large number of skin ...

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Feb 28, 2019

Here’s a statistic that might surprise you: approximately 7,000 rare disorders are known to exist, and new ones are discovered each year. It’s not something we think about often, in fact, the media almost never cover it. However, in recognition of Rare Disease Day, it’s important t...

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Feb 28, 2019

Recent research questions the popular notion that listening to music increases creativity. Instead, it proposes that quietness, or even background library noise, is more beneficial.After conducting a series of experiments with human volunteers, researchers from the University of Gävle in Sweden...

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Feb 28, 2019

The mania phase of bipolar disorder involves an unusually high level of energy and activity. It is common for people in this phase to experience racing thoughts, a lower need for sleep, and difficulty concentrating. Bipolar disorder is a condition that causes extreme changes in mood. There are diffe...

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Feb 28, 2019

New research from Aarhus University in Denmark suggests that people who have grown up in close contact with nature are much less likely to develop mental health problems in adulthood than peers who had less access to green space as children.According to recent studies, mental health problems have be...

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Feb 28, 2019

A recent study examines the health impact of consuming alcohol at different ages. The authors conclude that, for people over the age of 50, health risks may be less severe. Heavy drinking is linked to a range of serious health consequences. These include certain cancers, liver and heart disease, and...

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Feb 27, 2019

British neurologist Edward Wild is fluent in the complicated, tongue-twisting language of Huntington’s disease. But how do you explain to people living with Huntington’s what a triplet repeat on the huntingtin gene is? And how do you interpret the findings of a huntingtin-lowering drug?

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Feb 27, 2019

By the late 1960s, the lead had been recognized as a toxic substance for over a thousand years. The heavy metal made the mind “give way,” wrote the Greek physician Dioscorides in the 1st Century AD; Vitruvius, Julius Caesar’s engineer, wrote hundreds of years later that lead aquedu...

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Feb 27, 2019

The long process of drug discovery can take over a decade, from the identification of a target molecule, to release of a clinically approved drug that can be incorporated into therapeutic regimes. However, even after this long, convoluted, and the financially risky process is complete, treatment str...

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Feb 27, 2019

In her book, The Human Advantage, neuroscientist Suzana Herculano-Houzel points to the invention of cooking as the singular advancement that led to humans developing the largest primate brain. “Cooking is essentially the act of using fire to pre-digest food, and thus to get more energy out of ...

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Feb 27, 2019

As it does every year, Orphanet Journal of Rare Diseases is proud to partner with Findacure in its Student Voice essay contest. The overall winner will be published in the journal on Rare Disease Day, and we are proud to present the other finalists here. For this entry, undergraduate and masters stu...

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Feb 27, 2019

Over-the-counter medicines such as ibuprofen and acetaminophen are effective pain relievers, but long-term use can cause side effects. Prescription medications may be addictive and have even more adverse effects. What are the best natural ways to relieve pain? People have used essential oils, herbs,...

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Feb 27, 2019

A series of clinical trials have tested an experimental treatment for Parkinson's disease that uses a novel approach: administering the drug straight into the brain via implanted ports. The leading researchers believe this may be a "breakthrough" therapeutic strategy for neurological c...

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Feb 27, 2019

The 11th March marks the beginning of Brian Awareness Week. As part of this campaign, the ISRCTN team have compiled a collection of recent and ongoing clinical trials into Alzheimer’s disease.Alzheimer’s disease (AD) is the most common form of dementia, a syndrome characterized by brain ...

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Feb 27, 2019

In 2018, there were approximately 3,400 active agents in the immuno-oncology pipeline, a 67% increase from 2017. Clinical research in the field of immunotherapies is steadily increasing, especially in the area of oncology. The growing interest in immuno-oncology therapies is also reflected in its bo...

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Feb 27, 2019

For many solid tumors, treatments undergo a cycle: the drugs initially work well, the tumor shrinks, but then becomes resistant again. Stefanie Flückiger-Mangual, CEO of the Swiss biotech Tolremo, believes that this cycle can be stopped. Solid tumors often act like a recurring villain in a TV s...

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Feb 26, 2019

New research finds that triclosan, a popular antibacterial chemical, could have the opposite effect and make bacteria more rather than less resilient to antibiotic treatment. Triclosan is an antibacterial compound present in everyday household and personal-care products, such as toothpaste, soap, di...

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Feb 26, 2019

Developing personalized and precision medicine is the next breakthrough for drug developers particularly for cancer treatments. A recent review paper, from researchers at Rutgers University Department of Biomedicine Engineering, highlights its potentially transformative impact on cancer treatments.

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Feb 26, 2019

While many sectors have undergone this process by putting a data-driven approach in place, this has yet to be fully realized in pharmaceuticals. Sam Shah, director of digital development at NHS England has recently said the same is also true in the healthcare sector.

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Feb 26, 2019

I have always made sure my children received their vaccinations on time, and wow, my daughter is off to college soon! That’s a lot of shots over the course of 18 years. Before she goes, I will occasionally spoil her with her favorite, albeit pricey, Starbucks drink: a Venti Very Berry Hibiscus...

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Feb 26, 2019

The rise of big data, self-service, and more powerful and flexible end-user information visualization and preparation tools, consumer/ member/patient experience is impacting governance in a significant manner with regard to structure, decision rights, and accountabilities. End-users are gaining more...

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Feb 26, 2019

Some types of cancer, such as ovarian cancer, tend to remain undetected until they are too advanced for treatment to be effective. Now, an innovative tool may be able to detect cancer easily, quickly, and in minuscule amounts of blood.In a bid to find a simple, effective way of identifying hard-to-d...

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Feb 26, 2019

Researchers from Philadelphia University and Thomas Jefferson University have highlighted how building a strong immune memory response to rabies virus in the brain and spinal cord is key to protecting the CNS against infection.The rabies virus belongs to the Lyssavirus genus and transmission of the ...

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Feb 26, 2019

A recent study has linked a common prescription drug that people with arthritis use to relieve pain and inflammation to a heart valve problem.The drug, which has the generic name celecoxib and the brand name Celebrex, belongs to a category of nonsteroidal anti-inflammatory drugs (NSAIDs) known as CO...

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Feb 26, 2019

Babies often go a long time between bowel movements. Most of the time, it is normal for a baby to go days or even more than a week without a bowel movement. However, a baby may sometimes be constipated and need a little help. If a baby is constipated, a pediatrician may recommend using home remedies...

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Feb 26, 2019

The researchers found that women who worked for longer than 55 hours per week were more likely to exhibit symptoms of depression than women who worked the standard 35 to 40-hour week. Men who worked longer hours were not at an increased risk of depression, although they were more susceptible to prob...

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Feb 26, 2019

If back pain occurs when a person breathes, it can signal an underlying medical condition. In some cases the pain is sharp, and possible causes range from inflammation or infection of the chest to spinal curvature and lung cancer. Back pain while breathing can also indicate a medical emergency, such...

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Feb 26, 2019

Precision medicine is a focus of ongoing debate. In an environment of limited research funds, there are those who believe that precision medicine should be funded because it will improve population health and those who feel that it shouldn’t because it won’t. In a viewpoint published Jan...

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Feb 26, 2019

A DEXA scan usually assesses or measures bone density. It may also have used in determining body composition, such as the percentage of lean muscle and fat. The dual-energy X-ray absorptiometry (DEXA) scan uses two low-energy X-ray beams, which doctors direct toward the bones. Using dual energy leve...

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Feb 26, 2019

Although anecdotal sources and academic studies show that yoga can boost a person's well-being, some may need to use caution. A new study suggests that certain yoga poses can lead to bone injuries in people with osteoporosis or osteopenia.In the United States, about 24.5 percent of women ages 65...

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Feb 25, 2019

Data is ubiquitous in the pharma industry – a commodity that weaves an intricate web of information, flowing through all aspects of your business. It’s an amazing and unforgiving stream that immediately and permanently captures everything happening within your business operations, both i...

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Feb 25, 2019

Insomnia, often blamed on stress or bad sleep habits, may instead be closely linked to depression, heart disease, and other physiological disorders, a pair of deep dives into the human genome now reveals. “Both studies are very well done,” says psychologist Philip Gehrman of the Universi...

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Feb 25, 2019

Late-onset Alzheimer’s disease is extremely difficult to model in the laboratory, one reason why no successful therapy for it exists. But scientists are using new capabilities to create more accurate, more useful research tools, bringing new hope for progress and better outcomes for patients. ...

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Feb 25, 2019

Along with nausea, fatigue, and swollen feet, most women experience back pain at some points during pregnancy. Pregnancy-related back pain typically affects the lower back. According to one review that looked into the complaint, low-back pain affects more than two-thirds of women during pregnancy. B...

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Feb 25, 2019

Diabetes and high blood sugar go hand in hand. The type you have type 2, type 1, or prediabetes dictates how your body reacts to sugar in the blood. Since the reaction is often dependent on what you eat, diet is one of the best ways to help regulate fluctuating blood sugar levels. The American Diabe...

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Feb 25, 2019

New research could help to explain why some people report that they experience sensation in a missing limb, following amputation. Phantom limb is the sensation that the missing part remains attached. The vast majority of people with amputation report phantom sensations, often with pain. Now, an imag...

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Feb 25, 2019

Advancements in technology aren’t always about doing something new. Sometimes it’s about doing something old, but better, faster, and easier. From instant, reversible nose jobs to virtual dermatology, the science of skin care is bringing new innovations to skin treatments and technology....

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Feb 25, 2019

As it does every year, Orphanet Journal of Rare Diseases partnered with Findacure in its Student Voice essay contest. The overall winner will be published in the journal on Rare Disease Day, and we are proud to present the other finalists here. For this entry, undergraduate and masters students from...

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Feb 25, 2019

The terms pulled the muscle and muscle strain refers to an injury that involves an overstretched or torn muscle. A person with a muscle strain in the chest may experience sudden, sharp pain in this area. Although uncomfortable, a strained chest muscle is usually a minor injury that tends to heal wit...

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Feb 23, 2019

Whether you have an upcoming test on the circulatory system, are looking for a deeper understanding, or just need a refresher the following video is for you. You may be confused about the difference between arteries and veins, or you may believe some common circulatory system myths.

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Feb 23, 2019

A recent study categorizing people with obstructive sleep apnea based on their differing symptoms found a strong link between excessive daytime sleepiness and cardiovascular disease. Obstructive sleep apnea (OSA) causes sporadic airflow blockages during sleep. All of the different types of sleep apn...

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Feb 22, 2019

The DIA brings together researchers, pharma companies and innovative tech companies to addresses the challenges facing the pharma sector today. With the prevalence of AI across the business sector, it was no surprise that AI was a hot topic at two recent conferences: DIA Europe held in Vienna, and D...

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Feb 22, 2019

When a person has acute respiratory failure, the usual exchange between oxygen and carbon dioxide in the lungs does not occur. As a result, enough oxygen cannot reach the heart, brain, or the rest of the body. This can cause symptoms such as shortness of breath, a bluish tint in the face and lips, a...

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Feb 22, 2019

A panic attack is a sudden, intense onset of distress or fear. These feelings heighten for around 10 minutes until starting to fade. Panic attacks can occur at any time of the day or night. People may experience a panic attack without warning. Others may have frequent, unexpected attacks. Those who ...

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Feb 22, 2019

Language and communication are as vital as food and water. We communicate to exchange information, build relationships, and create art. In this Spotlight feature, we look at how language manifests in the brain, and how it shapes our daily lives.We are all born within a language, so to speak, and tha...

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Feb 22, 2019

Yerba santa, a plant with a long history of medicinal use in its native California, contains an active compound that could treat people with Alzheimer's disease one day. This was the conclusion that scientists at the Salk Institute for Biological Studies in La Jolla, CA came to after testing 400...

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Feb 22, 2019

Whooping cough, or pertussis, is a highly contagious condition. This infection is most common in infants, but people of all ages can contract it. Whooping cough symptoms tend to be less severe in adults than in children. Unvaccinated infants have the highest risk of developing severe symptoms and co...

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Feb 22, 2019

New research in The Journal of Physiology suggests that exercising at certain times of the day can alter the circadian rhythms, potentially offering a new therapy for jet lag and shift work. Circadian rhythms, which are "physical, mental, and behavioral changes that follow a daily cycle," ...

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Feb 21, 2019

David Clark, Ph.D., a Research Leader in Computer-aided Drug Design (CADD) at Charles River’s Harlow (UK) site, recently co-authored a review with Prof. Gisbert Schneider from the Swiss Federal Institute of Technology for the prestigious German chemistry journal Angewandte Chemie. The article ...

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