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The study uses brain cells in a dish to understand polygenic origins of schizophrenia THE STUDY USES BRAIN CELLS IN A DISH TO UNDERSTAND POLYGENIC ORIGINS OF SCHIZOPHRENIA

blog article

Oct 18, 2018

A recent study has established a new analytical method for investigating the complex genetic origins of mental illnesses using brain cells that are grown in a dish from human embryonic stem cells. The polygenic factors associated with psychiatric diseases are little understood, but this new approach...

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Key genomic differences in breast cancers of women of different ethnicity KEY GENOMIC DIFFERENCES IN BREAST CANCERS OF WOMEN OF DIFFERENT ETHNICITY

blog article

Oct 17, 2018

A study comparing DNA and RNA data from Nigerian breast cancer patients to patients in a United States database found that certain aggressive molecular features were far more prevalent in tumors from Nigerian women than in black or white American women. The study’s authors say those difference...

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Investigating tumour microenvironments for more effective treatments INVESTIGATING TUMOUR MICROENVIRONMENTS FOR MORE EFFECTIVE TREATMENTS

blog article

Oct 17, 2018

Researchers have gained insights into the microenvironment of different types of lung tumors, describing how the cell ecosystems may affect response to treatment. The microenvironment of a cell impact how it grows behaves and communicates with other nearby cells. Researchers aim to understand the mi...

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Using Facebook to predict depression USING FACEBOOK TO PREDICT DEPRESSION

blog article

Oct 17, 2018

New research uses over half a million Facebook status updates to predict depression diagnoses in people at risk. Depression is one of the most widespread mental health problems in the United States, with over 16 million adults have experienced at least one major depressive episode in their lifetimes...

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Keto diet may protect against cognitive decline KETO DIET MAY PROTECT AGAINST COGNITIVE DECLINE

blog article

Oct 16, 2018

Ketogenic, or keto, diets are low-carb and fat-rich, and many people who follow such regimens do it to shed excess weight. However, a keto diet may bring other benefits, too. In particular, it may help keep the brain healthy and young, as new research in mice seems to suggest. A keto diet is high in...

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Diabetes: Surprising new role of fat revealed DIABETES: SURPRISING NEW ROLE OF FAT REVEALED

blog article

Oct 16, 2018

A new study, published in the journal Cell Metabolism, challenges the current understanding of what causes diabetes. The findings may lead to new therapies. More than two decades ago, researchers suggested that the action of an enzyme called protein kinase C epsilon (PKCɛ) in the liver may cause dia...

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Neutrophil NEUTROPHIL'S ROLE DURING TUMOR PROGRESSION UNRAVELED

blog article

Oct 16, 2018

Researchers at The Wistar Institute have characterized the function of neutrophils, a type of white blood cells, during early stages of tumor progression, showing that they migrate from the bone marrow to distant sites and facilitate tumor cell seeding and establishment of metastasis. Importantly, t...

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Virtual Reality Shows We Eat with Our Eyes VIRTUAL REALITY SHOWS WE EAT WITH OUR EYES

blog article

Oct 16, 2018

Humans not only relish the sweet, savory and saltiness of foods, but they are influenced by the environment in which they eat. Cornell food scientists used virtual reality to show how people’s perception of real food can be altered by their surroundings, according to research published in the ...

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Lassa fever vaccine reveals new test for immunity LASSA FEVER VACCINE REVEALS NEW TEST FOR IMMUNITY

blog article

Oct 15, 2018

Lassa fever belongs to the same class of hemorrhagic fevers like Ebola. Like Ebola, it has been a major health threat in Western Africa, infecting 100,000-300,000 people and killing 5,000 per year. A new vaccine against both rabies and Lassa has demonstrated effective protection in animal models of ...

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Cancer stem cells use normal genes in abnormal ways CANCER STEM CELLS USE NORMAL GENES IN ABNORMAL WAYS

blog article

Oct 15, 2018

CDK1 is a “normal” protein – its presence drives cells through the cycle of replication. And MHC Class I molecules are “normal” as well – they present bits of proteins on the surfaces of cells for examination by the immune system. But a University of Colorado Canc...

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A cure for Alzheimer’s? Yes, a cure for Alzheimer’s! A CURE FOR ALZHEIMER’S? YES, A CURE FOR ALZHEIMER’S!

blog article

Oct 14, 2018

This is the most important column I’ve ever written.  The message is quite complex–dozens of new health parameters to test for and to optimize, all of them interacting in ways that will require new training for MDs.  The message is also as simple as it can be: There is a cure f...

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Drug target identified in oestrogen receptors DRUG TARGET IDENTIFIED IN OESTROGEN RECEPTORS

blog article

Oct 12, 2018

A team of scientists has described a strategy to disrupt the estrogen receptor in order to access a therapeutic drug target. Researchers from Case Western Reserve University School of Medicine have uncovered a previously uncharacterized, bridge-like structure within the human estrogen receptor which...

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Novel Genetic Study Sheds New Light On Risk Of Heart Attack NOVEL GENETIC STUDY SHEDS NEW LIGHT ON RISK OF HEART ATTACK

blog article

Oct 12, 2018

Loss of a protein that regulates mitochondrial function can greatly increase the risk of myocardial infarction (heart attack), Vanderbilt scientists reported Oct. 3 in the journal eLife. The study illustrates how “integrative genomics,” a combination of basic research, a human biobank li...

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Breast cancer: Omega-3-rich diet may stop tumors from spreading BREAST CANCER: OMEGA-3-RICH DIET MAY STOP TUMORS FROM SPREADING

blog article

Oct 11, 2018

New research shows that a diet rich in marine omega-3 fatty acids slows the growth and spread of breast cancer cells in female mice. The diet enriched with omega-3 also improved the rodents' survival. A vast body of research hails the benefits of a diet rich in omega-3 fatty acids. These he...

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Lung Cancer Deaths 28 Percent Lower In California Due To Long-Term, Aggressive Tobacco Control Programs LUNG CANCER DEATHS 28 PERCENT LOWER IN CALIFORNIA DUE TO LONG-TERM, AGGRESSIVE TOBACCO CONTROL PROGRAMS

blog article

Oct 11, 2018

Early adoption of tobacco control efforts in California led to fewer people ever smoking, reduced the amount used by those who do smoke and helped smokers quit at a younger age when their risk of developing lung cancer is lowest. As a result, say the authors of a new study published online October 1...

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Wired for Life: Study links infants WIRED FOR LIFE: STUDY LINKS INFANTS' BRAIN CIRCUITRY TO FUTURE HEALTH

blog article

Oct 11, 2018

Growth rates of brain circuits in infancy may help experts predict what a child's intelligence and emotional health could be when the child turns 4, a new study has found. Along with prior research, these findings could help future physicians identify cognitive and behavioral challenges in the f...

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Lassa Fever Vaccine Shows Promise and Reveals New Test for Immunity LASSA FEVER VACCINE SHOWS PROMISE AND REVEALS NEW TEST FOR IMMUNITY

blog article

Oct 11, 2018

Lassa fever belongs to the same class of hemorrhagic fevers like Ebola. Like Ebola, it has been a major health threat in Western Africa, infecting 100,000-300,000 people and killing 5,000 per year. A new vaccine against both rabies and Lassa has demonstrated effective protection in animal models of ...

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Micropeptide molecule restores heart function MICROPEPTIDE MOLECULE RESTORES HEART FUNCTION

blog article

Oct 10, 2018

Researchers have discovered a micro peptide molecule that can restore normal heart function in mice. The micropeptide works by preventing calcium dysregulation and remodeling of the heart and could be a promising new gene therapy target to treat heart failure.

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Existing drug may treat triple-negative breast cancer EXISTING DRUG MAY TREAT TRIPLE-NEGATIVE BREAST CANCER

blog article

Oct 09, 2018

The existing drug estradiol can inhibit tumor growth in a subtype of triple-negative breast cancer. The researchers may soon test the repurposed drug in phase II clinical trial. Triple-negative breast cancer is an aggressive form of breast cancer wherein tumors lack expression of three proteins. The...

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Paralysis from Rare Disorder: Stem Cell Therapy Trial Brings Hope PARALYSIS FROM RARE DISORDER: STEM CELL THERAPY TRIAL BRINGS HOPE

blog article

Oct 09, 2018

By injecting patients with stem cells engineered to repair the central nervous system – called progenitor cells – scientists are working to establish the first treatment that can repair spinal cords inflamed by transverse myelitis. If successful, the clinical trial could lead to similar ...

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Inflammatory Marker Tied To Kidney Decline In Healthy Adults INFLAMMATORY MARKER TIED TO KIDNEY DECLINE IN HEALTHY ADULTS

blog article

Oct 08, 2018

A large, multiethnic study of healthy individuals found that high blood levels of an inflammatory marker are linked with the long-term decline of kidney function. The results may shed light on biological mechanisms that spur chronic kidney disease. The findings were published today in the Journal of...

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Researchers develop a potential tool for efficacious targeted cancer therapy RESEARCHERS DEVELOP A POTENTIAL TOOL FOR EFFICACIOUS TARGETED CANCER THERAPY

blog article

Oct 08, 2018

Researchers at the Faculty of Pharmacy have developed PeptiENV, a cancer vaccine platform, which can be used to improve the therapeutic efficacy of oncolytic enveloped viruses currently in clinical use. With the help of this new cancer vaccine platform, the activation of the human immune response ag...

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Efficacy of PET imaging in managing chronic liver diseases EFFICACY OF PET IMAGING IN MANAGING CHRONIC LIVER DISEASES

blog article

Oct 08, 2018

Despite liver biopsies being powerful and reliable, they are also invasive, painful, limited and subject to complications. These effects may soon be a thing of the past for some patients. Research showing PET imaging with the 18F-FAC radiotracer can be used as a non-invasive substitute.

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AI algorithm accurately predicts Alzheimer’s disease onset AI ALGORITHM ACCURATELY PREDICTS ALZHEIMER’S DISEASE ONSET

blog article

Oct 05, 2018

Dr. Mallar Chakravarty, a computational neuroscientist at the Douglas Mental Health University Institute, and his colleagues from the University of Toronto and the Centre for Addiction and Mental Health, designed an algorithm that learns signatures from magnetic resonance imaging (MRI), genetics, an...

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Viruses In Blood Lead To Digestive Problems VIRUSES IN BLOOD LEAD TO DIGESTIVE PROBLEMS

blog article

Oct 04, 2018

While studying viruses best known for infecting the brain, researchers at Washington University School of Medicine in St. Louis stumbled upon clues to a conundrum involving a completely different part of the anatomy: the bowel, and why some people possibly develop digestive problems seemingly out of...

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Ovarian cancer: Taking regular low-dose aspirin can lower risk OVARIAN CANCER: TAKING REGULAR LOW-DOSE ASPIRIN CAN LOWER RISK

blog article

Oct 04, 2018

An analysis of data from hundreds of thousands of women in the United States has found that regularly taking low-dose aspirin is linked to a lower risk of developing ovarian cancer. The team found a 23 percent lower risk of ovarian cancer in women who reported that they had recently been freque...

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Study Links Individual HPV Types To HIV Infection STUDY LINKS INDIVIDUAL HPV TYPES TO HIV INFECTION

blog article

Oct 04, 2018

An international research team led by a scientist at the University of California, Riverside, has for the first time identified individual types of the human papillomavirus, or HPV, that are specifically linked to HIV infection. The study, published in the journal PLOS ONE, concludes that a person w...

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Nuclear tracer helps to study the aging brain NUCLEAR TRACER HELPS TO STUDY THE AGING BRAIN

blog article

Oct 04, 2018

A PET imaging radiotracer could help researchers understand the neurodegenerative disease and the aging brain. Researchers from John Hopkins University found that the radiotracer rapidly entered the brain, and was distributed quickly. Previous studies show a reduced density of the α4β2 ni...

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PSD-95 molecule reveal potential treatment for stroke patients PSD-95 MOLECULE REVEAL POTENTIAL TREATMENT FOR STROKE PATIENTS

blog article

Oct 03, 2018

A novel hybrid approach has revealed a 3D structure of a protein fragment that could serve as a drug target in treating stroke patients. The protein called “postsynaptic density protein of 95 kDa (PSD-95)” is positioned on neurons in the brain that are receiving chemical messages –...

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Why sudden cardiac arrests no longer peak in the morning WHY SUDDEN CARDIAC ARRESTS NO LONGER PEAK IN THE MORNING

blog article

Oct 03, 2018

New research, published in the journal Heart Rhythm, discovers that due to recent cultural shifts in our work schedules and daily stressors, sudden cardiac arrests no longer tend to occur in the mornings. Until now, the consensus has been that a range of cardiovascular events, such as angina, h...

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Targets for chronic kidney disease treatment TARGETS FOR CHRONIC KIDNEY DISEASE TREATMENT

blog article

Oct 02, 2018

DAB2 could be a target for chronic kidney disease treatments after researchers investigated how genetic variations drive the expression of genes within the cells of the kidney. The kidney works harder than any other organ in the body, tasked with extracting waste, balancing body fluids, forming urin...

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What are the risks of having too much amniotic fluid? WHAT ARE THE RISKS OF HAVING TOO MUCH AMNIOTIC FLUID?

blog article

Oct 02, 2018

Women experience polyhydramnios when too much amniotic fluid surrounds the fetus in the womb. This excess fluid can slightly increase the risk of complications during pregnancy and delivery. As a result, doctors usually monitor fluid levels regularly until a woman is ready to give birth. The amount ...

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How to identify psoriasis and ringworm HOW TO IDENTIFY PSORIASIS AND RINGWORM

blog article

Oct 02, 2018

Both psoriasis and ringworm cause red, scaly patches on the skin. Knowing the symptoms of each condition can help people to identify their rash. Psoriasis and ringworm are very different conditions. Ringworm is a fungal infection that will go away with treatment. Psoriasis is a chronic autoimmune co...

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Amazonian plant provides antitumour activity AMAZONIAN PLANT PROVIDES ANTITUMOUR ACTIVITY

blog article

Oct 01, 2018

Research conducted by scientists at the UPV/EHU-University of the Basque Country shows the amazonian Vismia baccifera plant causing oxidative stress in hepatic tumor cells. The Free Radicals and Oxidative Stress Group in the Faculty of Medicine and Nursing investigated the action of the plant of hum...

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Kidney disease biomarker could help detect COPD KIDNEY DISEASE BIOMARKER COULD HELP DETECT COPD

blog article

Sep 28, 2018

A biomarker commonly used with kidney disease could also indicate lung problems, primarily chronic obstructive pulmonary disease (COPD). Researchers reported a link between COPD and levels of albuminuria, the amount of albumin in urine. The researchers conducted their study by pooling information fr...

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KCNB1 may be a root cause of Alzheimer’s disease KCNB1 MAY BE A ROOT CAUSE OF ALZHEIMER’S DISEASE

blog article

Sep 27, 2018

A new mechanism has been developed that could contribute to Alzheimer’s disease and traumatic brain injury. Researchers from Rutgers University in New Jersey aim to launch a clinical trial to test this treatment in humans. Scientists have long since held the view of the popular theory where th...

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Sugar specific molecules show promising results for new allergy vaccine SUGAR SPECIFIC MOLECULES SHOW PROMISING RESULTS FOR NEW ALLERGY VACCINE

blog article

Sep 27, 2018

Using sugar molecules researchers have developed a new vaccine for hay fever that may reduce treatment times and increase the effectiveness of treatments. The vaccine, which is still at the earliest research stage, has been tested on mice. The method can potentially also be used to develop different...

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Breast tissue simulations address enhanced MRI delays BREAST TISSUE SIMULATIONS ADDRESS ENHANCED MRI DELAYS

blog article

Sep 25, 2018

Researchers from Purdue University argue that as no two women have the same breast tissue, MRI’s detecting and monitoring breast cancer should not treat all women the same way. As methods of ensuring the safety of new MRIs, clinical MRIs have not been able to progress to the standard of today&...

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Cryo-EM shows structure of TRPM2 CRYO-EM SHOWS STRUCTURE OF TRPM2

blog article

Sep 25, 2018

The atomic-level structure of TRPM2 has been revealed for the first time. Researchers at the Van Andel Research Institute (VARI) revealed the structure as a promising drug target for Alzheimer’s and bipolar disorder. The protein, TRPM2 is found throughout the body and is involved in regulating...

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New drug Metavert blocks the growth of pancreatic cancer in mice NEW DRUG METAVERT BLOCKS THE GROWTH OF PANCREATIC CANCER IN MICE

blog article

Sep 25, 2018

The study, led by non-profit health science center Cedars-Sinai, also demonstrated in mice that the drug, called Metavert, may prevent patients from developing a resistance to currently used pancreatic cancer chemotherapies. Commenting on the potential impact of their findings, study lead author Mou...

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Battling Superbugs: New Compounds Could Make Old Antibiotics New BATTLING SUPERBUGS: NEW COMPOUNDS COULD MAKE OLD ANTIBIOTICS NEW

blog article

Sep 25, 2018

With antibiotic-resistant “superbugs” now infecting 2 million people per year and a dearth of new medications in the pipeline to treat them, CU Boulder researchers are taking a novel approach to address the looming public health crisis: They’re helping develop new drugs to make old...

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Lung Inflammation From Childhood Asthma Linked With Later Anxiety LUNG INFLAMMATION FROM CHILDHOOD ASTHMA LINKED WITH LATER ANXIETY

blog article

Sep 25, 2018

Persistent lung inflammation may be one possible explanation for why having asthma during childhood increases your risk of developing anxiety later in life, according to Penn State researchers. In a study with mice, researchers found that childhood exposure to allergens was linked to persistent lung...

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Mitochondrial diseases could be treated with gene therapy MITOCHONDRIAL DISEASES COULD BE TREATED WITH GENE THERAPY

blog article

Sep 24, 2018

Researchers have developed a genome-editing tool for the potential treatment of mitochondrial diseases: serious and often fatal conditions which affect 1 in 5,000 people. The researchers, led by the University of Cambridge, applied an experimental gene therapy treatment in mice and were able to succ...

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Psoriasis and lupus: What PSORIASIS AND LUPUS: WHAT'S THE DIFFERENCE?

blog article

Sep 24, 2018

Psoriasis and lupus are both autoimmune conditions that can affect people's skin. Although they share some symptoms, they are separate disorders. It is possible for a person to have both lupus and psoriasis, or psoriatic arthritis. The treatments and complications are different for each disorder...

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Chemical tags make differences in cell fate and gene expression CHEMICAL TAGS MAKE DIFFERENCES IN CELL FATE AND GENE EXPRESSION

blog article

Sep 21, 2018

Scientists at the Centre for Genomic Regulation in Spain have uncovered the role of chemical ‘tags’ in controlling genes involved in mammalian development. The research was led by Professor Luciano Di Croce and Professor Marc Marti-Renom, and focused on genes known as bivalent promoters;...

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Synthetic organelle shows how tiny puddle-organs in our cells work SYNTHETIC ORGANELLE SHOWS HOW TINY PUDDLE-ORGANS IN OUR CELLS WORK

blog article

Sep 20, 2018

An illustration of part of a synthetic organelle without a membrane. Here we see two layers that phase separate like oil and water, but both layers are water. There is no oil. Each layer contains a different solute that gives it its own chemical thermodynamics, keeping it separate from the other one...

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Can a heart treatment lower depression and anxiety? CAN A HEART TREATMENT LOWER DEPRESSION AND ANXIETY?

blog article

Sep 20, 2018

Many people who have atrial fibrillation experience symptoms of mood disorders, such as anxiety and depression. Do particular treatments for this condition help resolve such symptoms? A new study suggests they might. Atrial fibrillation (A-fib) is a common condition characterized by an irregula...

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Biomarkers: Embracing a Holistic View Is Key to the Future of Precision Medicine BIOMARKERS: EMBRACING A HOLISTIC VIEW IS KEY TO THE FUTURE OF PRECISION MEDICINE

blog article

Sep 19, 2018

We are entering an era where healthcare as we know it is going to be revolutionized.  We’re beginning to realize the potential that biomarkers hold for the world of medicine. By enabling medical scientists to stratify patients into clear, targeted groups categorized by their susceptibilit...

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Do low vitamin D levels increase breast cancer risk? DO LOW VITAMIN D LEVELS INCREASE BREAST CANCER RISK?

blog article

Sep 19, 2018

A new study from Brazil corroborates the evidence gathered by previous research, suggesting that women with low levels of vitamin D after menopause onset have a higher risk of developing breast cancer. The National Cancer Institute (NCI) notes that "approximately 12.4 percent of women will...

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What are the stages of Crohn WHAT ARE THE STAGES OF CROHN'S DISEASE?

blog article

Sep 19, 2018

Crohn's disease is a long-term condition that causes inflammation in the digestive tract. Doctors do not categorize Crohn's into different stages because symptoms can vary considerably over time, which can make it unpredictable. Crohn's disease is a type of inflammatory bowel disease. It...

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Scientists develop means to manipulate nuclear pore numbers SCIENTISTS DEVELOP MEANS TO MANIPULATE NUCLEAR PORE NUMBERS

blog article

Sep 19, 2018

If you consider the cell nucleus as a bank for DNA, nuclear pores are the security doors around its perimeter. However, more security doors aren’t necessarily desirable, evidenced by the fact that some cancer cells contain a dramatic excess of nuclear pores. Scientists at the Salk Institute re...

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Young Children’s Oral Bacteria May Predict Obesity YOUNG CHILDREN’S ORAL BACTERIA MAY PREDICT OBESITY

blog article

Sep 19, 2018

Weight gain trajectories in early childhood are related to the composition of oral bacteria of two-year-old children, suggesting that this understudied aspect of a child’s microbiota the collection of microorganisms, including beneficial bacteria, residing in the mouth could serve as an early ...

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Targeting This Key Bacterial Molecule Could Reduce The Need For Antibiotics TARGETING THIS KEY BACTERIAL MOLECULE COULD REDUCE THE NEED FOR ANTIBIOTICS

blog article

Sep 18, 2018

Stanford researchers have shown that bacteria involved in urinary tract infections (UTI) rely on a novel chemical form of the molecule cellulose to stick to bladder cells. The finding, published in the journal of the Proceedings of the National Academy of Sciences, could lead to new ways of treating...

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Quick And Easy Test For Viral Infections Reduces Hospital Admissions And Antibiotic Use QUICK AND EASY TEST FOR VIRAL INFECTIONS REDUCES HOSPITAL ADMISSIONS AND ANTIBIOTIC USE

blog article

Sep 17, 2018

A quick and easy test for viral infections can reduce unnecessary antibiotic use and hospital admissions, according to new research presented to the European Respiratory Society International Congress Monday. The test, which takes just 50 minutes to obtain results, could save hospitals around €...

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Paracetamol Use In Infancy Is Linked To Increased Risk Of Asthma In Some Teenagers PARACETAMOL USE IN INFANCY IS LINKED TO INCREASED RISK OF ASTHMA IN SOME TEENAGERS

blog article

Sep 17, 2018

Children who take paracetamol during their first two years of life may be at a higher risk of developing asthma by the age of 18, especially if they have a particular genetic makeup, according to new research presented at the European Respiratory Society International Congress today (Monday). Ms. Xi...

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Injuries Associated With Infant Walkers Still Sending Children To ER INJURIES ASSOCIATED WITH INFANT WALKERS STILL SENDING CHILDREN TO ER

blog article

Sep 17, 2018

Although infant walkers provide no benefit to children and pose the significant injury risk, many are still being used in US homes. A new study from researchers in the Center for Injury Research and Policy at Nationwide Children’s Hospital examined characteristics of infant walker-related inju...

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Gut Bacteria’s Shocking Secret: They Produce Electricity GUT BACTERIA’S SHOCKING SECRET: THEY PRODUCE ELECTRICITY

blog article

Sep 17, 2018

While bacteria that produce electricity have been found in exotic environments like mines and the bottoms of lakes, scientists have missed a source closer to home: the human gut. UC Berkeley scientists discovered that a common diarrhea-causing bacterium, Listeria monocytogenes, produces electricity ...

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Brain cell identified as BRAIN CELL IDENTIFIED AS 'MEDIATOR OF DISEASE'

blog article

Sep 17, 2018

Brain inflammation is a marker of multiple sclerosis, Alzheimer's, and some psychiatric disorders. A new study finds a subtype of brain cell that is key in neuroinflammation, bringing us closer to new treatments for multiple central nervous system diseases. Recent estimates suggest that 1 millio...

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Daily low-dose aspirin found to have no effect on healthy life span in older people DAILY LOW-DOSE ASPIRIN FOUND TO HAVE NO EFFECT ON HEALTHY LIFE SPAN IN OLDER PEOPLE

blog article

Sep 16, 2018

ASPREE is an international, randomized, double-blind, placebo-controlled trial that enrolled 19,114 older people (16,703 in Australia and 2,411 in the United States). The study began in 2010 and enrolled participants aged 70 and older; 65 was the minimum age of entry for African-American and Hispani...

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Chronic pain and the power of placebo CHRONIC PAIN AND THE POWER OF PLACEBO

blog article

Sep 16, 2018

A new study has asked whether certain people with chronic pain should be given sugar pills to manage their symptoms. Scientists tap into the individual differences that make some people more susceptible to a placebo. A placebo is a medical intervention be it a pill, injection, or sham surgery that h...

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Timing could be crucial when taking medication TIMING COULD BE CRUCIAL WHEN TAKING MEDICATION

blog article

Sep 14, 2018

Researchers used bioinformatics tools to analyze thousands of human tissue samples, creating a new database of daily circadian rhythms in human gene activity. The scientists, from Cincinnati Children’s Hospital Medical Centre, mention that their results could have significant implications for ...

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Developing RNA Medicines for Rare Genetic Diseases DEVELOPING RNA MEDICINES FOR RARE GENETIC DISEASES

blog article

Sep 11, 2018

There are approximately 7,000 known rare diseases, however, less than 6% of these have a treatment. It is estimated that between 25–35 million Americans live with a rare disease. The company ProQR is dedicated to developing new therapeutics for patients living with untreated rare diseases. We ...

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How does rheumatoid arthritis affect the elbow? HOW DOES RHEUMATOID ARTHRITIS AFFECT THE ELBOW?

blog article

Sep 10, 2018

Rheumatoid arthritis can affect any of the joints in the body, including the elbow joint. This long-term condition causes inflammation, stiffness, and pain around affected joints. Rheumatoid arthritis (RA) in the elbow can be very uncomfortable, and it may affect daily tasks, such as reaching for ob...

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New cancer vaccine is 100 percent successful in mouse model NEW CANCER VACCINE IS 100 PERCENT SUCCESSFUL IN MOUSE MODEL

blog article

Sep 10, 2018

Scientists have developed a new vaccine that — in conjunction with existing therapies — cannot only treat aggressive melanoma but also prevent its recurrence. Researchers from the Scripps Research Institute in San Diego, CA, recently worked with experts from other institutions to develop...

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These supplements may actually harm your health THESE SUPPLEMENTS MAY ACTUALLY HARM YOUR HEALTH

blog article

Sep 09, 2018

New research warns that a number of weight loss and workout supplements contain — without accurately listing — potentially harmful doses of a substance that has been ruled as unsafe. Recently, scientists looked into whether a range of supplements used as weight loss or workout aids may a...

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Single-Dose Drug Shortens Flu Symptoms by ~1 Day SINGLE-DOSE DRUG SHORTENS FLU SYMPTOMS BY ~1 DAY

blog article

Sep 07, 2018

A single dose of a new influenza drug can significantly shorten the duration of the illness in teens and adults, according to a study published in the prestigious New England Journal of Medicine. The article reports the results of two multicenter, double-blind, randomized clinical trials. Both found...

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Building a Better Brain-in-a-Dish, Faster and Cheaper BUILDING A BETTER BRAIN-IN-A-DISH, FASTER AND CHEAPER

blog article

Sep 07, 2018

The development of a rapid, cost-effective method to create human cortical organoids directly from primary cells has been described by researchers at the University of California San Diego School of Medicine, in a paper published in Stem Cells and Development. Experimental studies of developing huma...

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Novel Cancer Vaccine Against Melanoma Tested NOVEL CANCER VACCINE AGAINST MELANOMA TESTED

blog article

Sep 07, 2018

An experimental cancer vaccine that boosts the immune system’s ability to fight cancers could work in tandem with other cancer therapies to fight aggressive tumors, scientists reported recently in the Proceedings of the National Academy of Sciences. The researchers demonstrated that adding a m...

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How uncontrolled inflammation leads to brain cell loss HOW UNCONTROLLED INFLAMMATION LEADS TO BRAIN CELL LOSS

blog article

Sep 06, 2018

In a study of inflammation mechanisms in the brain, researchers from the University of Bonn in Germany have identified how, as we get older, a vicious cycle of poorly regulated inflammatory responses leads to the loss of brain cells. Recently, those researchers conducted a study that investigat...

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The alchemy of healing: Researchers turn open wounds into the skin THE ALCHEMY OF HEALING: RESEARCHERS TURN OPEN WOUNDS INTO THE SKIN

blog article

Sep 05, 2018

Plastic surgery to treat large cutaneous ulcers, including those seen in people with severe burns, bedsores or chronic diseases such as diabetes, may someday be a thing of the past. Scientists at the Salk Institute have developed a technique to directly convert the cells in an open wound into new sk...

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DNA of early medieval Alemannic warriors and their entourage decoded DNA OF EARLY MEDIEVAL ALEMANNIC WARRIORS AND THEIR ENTOURAGE DECODED

blog article

Sep 05, 2018

In 1962, an Alemannic burial site containing human skeletal remains was discovered in Niederstotzingen (Baden-Württemberg, Germany). Researchers at the Eurac Research Centre in Bozen-Bolzano, Italy, and at the Max Planck Institute for the Science of Human History in Jena, Germany, have now exam...

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Applications of high content screening in autophagy APPLICATIONS OF HIGH CONTENT SCREENING IN AUTOPHAGY

blog article

Sep 04, 2018

Autophagy is an important process to maintain cellular homeostasis and function. Basal levels of autophagy are essential for most cells to remove unwanted protein aggregates and damaged organelles in order to prevent diseases. However, sometimes cells are unable to maintain physiological stability a...

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Complex biology for the precision medicine era: re-thinking the drug discovery process COMPLEX BIOLOGY FOR THE PRECISION MEDICINE ERA: RE-THINKING THE DRUG DISCOVERY PROCESS

blog article

Sep 04, 2018

Complex biology is a discipline acknowledging that performing biological experiments in vitro should take account of the complexity of the biological context. While this may be a noble aim, it has proven difficult to incorporate these elements into the drug discovery process, especially at the high-...

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New clues found to understanding relapse in breast cancer NEW CLUES FOUND TO UNDERSTANDING RELAPSE IN BREAST CANCER

blog article

Sep 04, 2018

A large genomic analysis has linked certain DNA mutations to a high risk of relapse in estrogen receptor-positive breast cancer, while other mutations were associated with better outcomes, according to researchers from Washington University School of Medicine in St. Louis, the Baylor College of Medi...

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Computational analysis identifies a new clinical phenotype of severe malaria COMPUTATIONAL ANALYSIS IDENTIFIES A NEW CLINICAL PHENOTYPE OF SEVERE MALARIA

blog article

Sep 04, 2018

There are more clinical phenotypes of severe malaria than those defined by the World Health Organization (WHO), according to a study led by ISGlobal, an institution supported by “la Caixa” Foundation. The results indicate that heart failure can be a pathogenic mechanism of disease, which...

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A step closer to preventing autoimmune response to gene therapy A STEP CLOSER TO PREVENTING AUTOIMMUNE RESPONSE TO GENE THERAPY

blog article

Sep 04, 2018

Stanford University School of Medicine researchers used a mouse model in an effort to counter the body’s autoimmune reaction to the normal protein that it’s encountering for the first time. The model they used accurately recapitulates Duchenne muscular dystrophy; a disease encountered in...

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10-Year Risk Estimates For Dementia May Help Early Targeted Prevention 10-YEAR RISK ESTIMATES FOR DEMENTIA MAY HELP EARLY TARGETED PREVENTION

blog article

Sep 04, 2018

A Danish study provides 10-year absolute risk estimates for dementia specific to age, sex and common variation in the APOE gene, which may help identify high-risk individuals who potentially could benefit from early targeted prevention. The study is published in CMAJ (Canadian Medical Association Jo...

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Is it time to dismiss the myths and fears about psoriasis? IS IT TIME TO DISMISS THE MYTHS AND FEARS ABOUT PSORIASIS?

blog article

Sep 03, 2018

Psoriasis is a long-lasting noncontagious skin condition that can cause much discomfort. Because of its unpleasing appearance, psoriasis is often accompanied by stigma. A new study reveals that myths surrounding the skin condition still persist in this era of readily. Characterized by reddish, scaly...

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Deadly venoms may drive medical advances DEADLY VENOMS MAY DRIVE MEDICAL ADVANCES

blog article

Sep 02, 2018

Despite the fast pace of research, there are still many diseases that defy treatment. A paper, recently published in the journal Science, asks whether venom might help design innovative treatments. Venomous plants and animals are incredibly common 15 percent of Earth's biodiversity, according to...

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Cardiovascular disease: Study finds the best drugs for prevention CARDIOVASCULAR DISEASE: STUDY FINDS THE BEST DRUGS FOR PREVENTION

blog article

Sep 01, 2018

A large cohort study has identified which treatment combinations work best for people with high blood pressure who are at risk for heart disease. Taking both blood pressure drugs and statins might be the best choice, the researchers find. Researchers from the William Harvey Research Institute at Que...

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Matcha green tea kills cancer stem cells MATCHA GREEN TEA KILLS CANCER STEM CELLS

blog article

Aug 31, 2018

Scientists from the University of Salford used breast cancer stem cells to test Matcha green tea. Matcha is a stone-ground powder made from green tea leaves and has often been hailed as a ‘miracle food’ containing properties to treat and prevent disease. The researchers tested Matcha gre...

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Scientists decode opium poppy genome SCIENTISTS DECODE OPIUM POPPY GENOME

blog article

Aug 30, 2018

Scientists have determined the DNA code of the opium poppy genome, uncovering key steps in how the plant evolved to produce the pharmaceutical compounds used to make vital medicines. The discovery may pave the way for scientists to improve yields and the disease resistance of the medicinal plant, se...

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Potential drug to cure ciliopathies POTENTIAL DRUG TO CURE CILIOPATHIES

blog article

Aug 30, 2018

Ciliopathies are rare disorders involving functional and structural abnormalities of cilia. Although they are rare, they may reach 1 in 1,000 births. Unfortunately, there are no small-molecule drugs for treating ciliary defects. A KAIST research team conducted successful research that introduces a p...

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Scientists discover compound for a non-addictive painkiller SCIENTISTS DISCOVER COMPOUND FOR A NON-ADDICTIVE PAINKILLER

blog article

Aug 30, 2018

Scientists have developed a chemical compound which could potentially lead to becoming an effective non-addictive painkiller. Researchers from the Wake Forest School of Medicine, along with support from the National Institute on Drug Abuse developed At-121, a compound which suppresses the addictive ...

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Electronic Device Planted in Brain Could Stop Seizures ELECTRONIC DEVICE PLANTED IN BRAIN COULD STOP SEIZURES

blog article

Aug 30, 2018

Researchers have successfully demonstrated how an electronic device implanted directly into the brain can detect, stop and even prevent epileptic seizures. The researchers, from the University of Cambridge, the École Nationale Supérieure des Mines and INSERM in France, implanted the de...

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Novel imaging biomarker to help predict coronary inflammation NOVEL IMAGING BIOMARKER TO HELP PREDICT CORONARY INFLAMMATION

blog article

Aug 29, 2018

Researchers have identified a novel imaging biomarker, which has been found to be able to predict all-cause and cardiac mortality by measuring inflammation of fatty tissue surrounding the coronary arteries. Coronary artery inflammation inhibits fatty tissue formation surrounding the blood vessels, k...

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Scientists develop TSA-Seq technique for precise 3D mapping of the human genome SCIENTISTS DEVELOP TSA-SEQ TECHNIQUE FOR PRECISE 3D MAPPING OF THE HUMAN GENOME

blog article

Aug 29, 2018

Researchers from the University of Illinois at Urbana-Champaign have reported a new technique that can measure the position of every single gene in the nucleus to build a 3D picture of the genome’s layout, called tyramide signal amplification sequencing (TSA-Seq). The location of genes be they...

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Brain-heart link points at potential biomarker for trauma-induced epilepsy BRAIN-HEART LINK POINTS AT POTENTIAL BIOMARKER FOR TRAUMA-INDUCED EPILEPSY

blog article

Aug 28, 2018

Concentrating on subjects who suffered physical or infectious brain insults, Penn State researchers studied mouse models of cerebral malaria, which often causes epilepsy in those who survive. Results of their study indicate a possible biomarker that signals which patients will proceed to develop epi...

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Scientists show combined immunotherapy treatment effective against advanced melanoma SCIENTISTS SHOW COMBINED IMMUNOTHERAPY TREATMENT EFFECTIVE AGAINST ADVANCED MELANOMA

blog article

Aug 28, 2018

The UCLA-led research showed that using the immunotherapy drug pembrolizumab and the experimental agent SD-101 a sequence of nucleic acids that mimics a bacterial infection altered the microenvironment surrounding the tumor in a way that enabled the immune system to more effectively attack cancer. T...

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Researchers Reveal Cause Of Aggressive Skin Cancer In Patients With Butterfly Syndrome RESEARCHERS REVEAL CAUSE OF AGGRESSIVE SKIN CANCER IN PATIENTS WITH BUTTERFLY SYNDROME

blog article

Aug 28, 2018

Patients with a rare skin disease, commonly called Butterfly Syndrome, that causes chronic blistering and extensive scarring also develop an aggressive and fatal form of cancer early in life. Now an international team of scientists led by researchers at the Sidney Kimmel Cancer Center – Jeffer...

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Scientists identify a new kind of human brain cell SCIENTISTS IDENTIFY A NEW KIND OF HUMAN BRAIN CELL

blog article

Aug 27, 2018

One of the most intriguing questions about the human brain is also one of the most difficult for neuroscientists to answer: What sets our brains apart from those of other animals? "We really don't understand what makes the human brain special," said Ed Lein, Ph.D., Investigator at the ...

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Jury Still Out On Aspirin A Day To Prevent Heart Attack And Stroke JURY STILL OUT ON ASPIRIN A DAY TO PREVENT HEART ATTACK AND STROKE

blog article

Aug 26, 2018

The jury is still out on whether people at moderate risk of a first heart attack or stroke should take the daily aspirin to lower their risk, according to late-breaking results from the ARRIVE study1 presented today in a Hot Line Session at ESC Congress 20182 and with simultaneous publication in the...

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Why Polluted Air May Be A Threat To Your Kidneys WHY POLLUTED AIR MAY BE A THREAT TO YOUR KIDNEYS

blog article

Aug 26, 2018

There is good evidence that polluted air increases the risk of respiratory problems such as asthma as well as organ inflammation, worsening of diabetes and other life-threatening conditions. But new research suggests air pollution can also fuel something else: chronic kidney disease, or CKD, which o...

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Scientists Have Developed An Effective Marker For Cancer Diagnosis And Therapy SCIENTISTS HAVE DEVELOPED AN EFFECTIVE MARKER FOR CANCER DIAGNOSIS AND THERAPY

blog article

Aug 26, 2018

A research group consisting of scientists from NUST MISIS, the Technical University of Munich, Helmholtz Zentrum München, the University of Duisburg-Essen, and the University of Oldenburg has developed a system that allows doctors to both improve the accuracy of diagnosing malignant cells and t...

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NanoMIPs efficiently target and eliminate cancer cells NANOMIPS EFFICIENTLY TARGET AND ELIMINATE CANCER CELLS

blog article

Aug 24, 2018

A joint research team from Russia and the UK has demonstrated the possibility of developing a new type of anti-neoplastic drugs based on nanoMIPs, or “plastic antibodies.” NanoMIPs are synthetic polymers that can function as antibodies, selectively binding to target proteins on the surfa...

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Alzheimer’s One Day May Be Predicted During Eye Exam ALZHEIMER’S ONE DAY MAY BE PREDICTED DURING EYE EXAM

blog article

Aug 24, 2018

It may be possible in the future to screen patients for Alzheimer’s disease using an eye exam. Using technology similar to what is found in many eye doctors’ offices, researchers at Washington University School of Medicine in St. Louis have detected evidence suggesting Alzheimer’s ...

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Handheld probe images photoreceptors in children HANDHELD PROBE IMAGES PHOTORECEPTORS IN CHILDREN

blog article

Aug 23, 2018

The technology, based on adaptive optics, will make it easier for physicians and scientists to observe these cells to diagnose eye diseases and make early detection of brain-related diseases and trauma. Photoreceptors are specialized neurons that comprise the light-sensing cells of the retina, an ex...

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AI system detects cancer tumours missed by conventional diagnostics AI SYSTEM DETECTS CANCER TUMOURS MISSED BY CONVENTIONAL DIAGNOSTICS

blog article

Aug 23, 2018

Computer engineers have ‘taught’ a computer to identify tiny specs of lung cancer in CT scan images, often missed by radiologists. Engineers have used machine learning to ‘teach’ a computer how to detect tiny specs of lung cancer in CT scans. Researchers from the University o...

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What are gastric and duodenal ulcers? WHAT ARE GASTRIC AND DUODENAL ULCERS?

blog article

Aug 23, 2018

Gastric and duodenal ulcers are types of peptic ulcer. The main distinction is that they affect different parts of the digestive tract. A person could have both at the same time. Some causes of peptic ulcers include an excess of stomach acid, bacterial infection, and certain medications. In this art...

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Modified-RNA vaccine elicits protective response against influenza MODIFIED-RNA VACCINE ELICITS PROTECTIVE RESPONSE AGAINST INFLUENZA

blog article

Aug 22, 2018

A universal flu vaccine that protects people against most influenza strains is one step closer to reality, with a study from the Perelman School of Medicine at the University of Pennsylvania. The candidate vaccine elicited a strong antibody response to a structure on the surface of flu viruses, call...

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Blood test may identify cancer patients who won’t respond to immunotherapy BLOOD TEST MAY IDENTIFY CANCER PATIENTS WHO WON’T RESPOND TO IMMUNOTHERAPY

blog article

Aug 22, 2018

Patients who are unlikely to benefit from a commonly used immunotherapy for bladder cancer could be identified by a simple blood test, according to researchers at Brighton and Sussex Medical School (BSMS). This could potentially save months of unnecessary and ineffective treatment. Currently, 30-40%...

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Research team develops predictor for immunotherapy response in melanoma RESEARCH TEAM DEVELOPS PREDICTOR FOR IMMUNOTHERAPY RESPONSE IN MELANOMA

blog article

Aug 21, 2018

In a new study, researchers developed a gene expression predictor that can indicate whether melanoma in a specific patient is likely to respond to treatment with immune checkpoint inhibitors, a novel type of immunotherapy. The predictor was developed by Dr Noam Auslander, with other researchers in t...

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The Agricultural Perspective on Water Contamination by Pharmaceuticals THE AGRICULTURAL PERSPECTIVE ON WATER CONTAMINATION BY PHARMACEUTICALS

blog article

Aug 21, 2018

The United States Environmental Protection Agency has recognized pharmaceuticals and personal care products (PPCPs) [1] to be part of a class of materials known as “emerging contaminants”. Emerging contaminants [2] can be either manmade or naturally occurring compounds that have recently...

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Can gut bacteria help us achieve a CAN GUT BACTERIA HELP US ACHIEVE A 'UNIVERSAL' BLOOD TYPE?

blog article

Aug 21, 2018

In light of the global relief efforts required after natural disasters, which have often called for blood transfusions, researchers are looking for effective ways of turning other blood types into the "universal. Researchers press on with their quest for a safe and effective method to convert o...

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Vitamin B-3 may treat and prevent acute kidney injury VITAMIN B-3 MAY TREAT AND PREVENT ACUTE KIDNEY INJURY

blog article

Aug 21, 2018

New research suggests that taking vitamin B-3 orally might soon become an effective way to treat or even prevent acute kidney injury. In acute kidney injury, the kidneys suddenly stop functioning usually as a result of complications during hospitalization. Approximately 10 percent of adults who are ...

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How much protein is too much? HOW MUCH PROTEIN IS TOO MUCH?

blog article

Aug 20, 2018

Proteins are the most versatile molecules for the human body and are key to almost all biological processes. The average recommended dietary allowance for protein is calculated using the ratio of 1 gram of protein for every 1 kilogram of a person's body weight.

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Maple Leaf Extract Could Nip Skin Wrinkles In The Bud MAPLE LEAF EXTRACT COULD NIP SKIN WRINKLES IN THE BUD

blog article

Aug 20, 2018

Maple trees are best known for their maple syrup and lovely fall foliage. But it turns out that the beauty of those leaves could be skin-deep and that’s a good thing. Today, scientists report that an extract from the leaves may prevent wrinkles. The scientists had previously studied the chemis...

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Largest Oral HPV Study In England Shows Infection Rates Lower Than Expected LARGEST ORAL HPV STUDY IN ENGLAND SHOWS INFECTION RATES LOWER THAN EXPECTED

blog article

Aug 20, 2018

Infection rates of high-risk human papillomavirus (HR-HPV) oral infection in England are lower than expected, compared to previous US studies. The research, conducted by the University of Sheffield, also strengthens the evidence that smoking and sexual behavior were shown to be risk factors for oral...

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To Find And Disarm: Scientists Develop Platform To Kill Cancer Cells TO FIND AND DISARM: SCIENTISTS DEVELOP PLATFORM TO KILL CANCER CELLS

blog article

Aug 17, 2018

The new treatment will serve as both the diagnosis and treatment of malignant tumors. This breakthrough in the technologies of cancer diagnosis and treatment was made by an interdisciplinary Russian-German collaboration of chemists, physicists, and biologists from NUST MISIS, Lomonosov Moscow State ...

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Developing Neuroprotective Therapies: Defending the Nervous System from Damage DEVELOPING NEUROPROTECTIVE THERAPIES: DEFENDING THE NERVOUS SYSTEM FROM DAMAGE

blog article

Aug 17, 2018

The University of Texas MD Anderson Cancer Center and Accelerator Life Science Partners recently announced the launch of Magnolia Neurosciences Corporation – a biopharmaceutical company advancing a new class of neuroprotective medicines. To learn more about Magnolia Neurosciences, we spoke to ...

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Is it safe to mix aspirin and ibuprofen? IS IT SAFE TO MIX ASPIRIN AND IBUPROFEN?

blog article

Aug 16, 2018

Taking aspirin and ibuprofen at the same time can cause side effects. The safety of mixing these drugs depends on the reasons why people are taking them. Aspirin and ibuprofen are both pain relievers from the same family of medicines known as non-steroidal anti-inflammatory drugs or NSAIDs. Because ...

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What are the natural ways to prevent prostate cancer? WHAT ARE THE NATURAL WAYS TO PREVENT PROSTATE CANCER?

blog article

Aug 16, 2018

There is no single best way to prevent prostate cancer, but several natural methods can help. These include maintaining a healthful weight, exercising, and eating plenty of fruits and vegetables. After skin cancer, prostate cancer is the type most common among American men, according to the Centers ...

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New chemical causes deadly brain cancer to self-destruct NEW CHEMICAL CAUSES DEADLY BRAIN CANCER TO SELF-DESTRUCT

blog article

Aug 16, 2018

Scientists have discovered a chemical compound that cuts off the "energy supply" to glioblastoma cells, making them self-destruct.  A newly discovered chemical may improve brain cancer survival. A glioblastoma is a deadly form of brain cancer. Glioblastoma tumors emerge from the ...

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Why cannabis relieves IBD symptoms WHY CANNABIS RELIEVES IBD SYMPTOMS

blog article

Aug 14, 2018

New research, published in the Journal of Clinical Investigation, reveals the molecular mechanism that explains why cannabis could help treat inflammatory bowel disease. Inflammatory bowel disease (IBD) is an umbrella term that describes inflammatory conditions affecting the gastrointestinal tract, ...

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New technique treats prostate cancer in just five radiotherapy sessions NEW TECHNIQUE TREATS PROSTATE CANCER IN JUST FIVE RADIOTHERAPY SESSIONS

blog article

Aug 14, 2018

A new clinical trial shows the benefits of an innovative form of radiation therapy, which delivers the radiation in only five sessions instead of the usual 37. The National Cancer Institute (NCI) estimates that prostate cancer affects over 160,000 people in the United States. In 2018, almost 30,000 ...

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Highly Effective and Selective Molecule Developed to Fight Malaria HIGHLY EFFECTIVE AND SELECTIVE MOLECULE DEVELOPED TO FIGHT MALARIA

blog article

Aug 13, 2018

A novel laboratory-synthesized molecule is a strong candidate for the development of a new antimalarial drug. The possibility of a new drug offers hope for thousands of patients infected by Plasmodium falciparum, one of the parasites that cause malaria, above all because tests have proved that the m...

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3D Electron Microscopy of Synapse Building 3D ELECTRON MICROSCOPY OF SYNAPSE BUILDING

blog article

Aug 13, 2018

New research from a team led by Marshall University scientist W. Christopher Risher, Ph.D., reveals novel molecular insights into how multiple cell types drive the formation and maturation of brain circuits. The brain is a highly complex organ that enables us to think, remember, move and perform sim...

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Glaucoma May Be An Autoimmune Disease GLAUCOMA MAY BE AN AUTOIMMUNE DISEASE

blog article

Aug 10, 2018

Glaucoma, a disease that afflicts nearly 70 million people worldwide, is something of a mystery despite its prevalence. Little is known about the origins of the disease, which damages the retina and optic nerve and can lead to blindness. A new study from MIT and Massachusetts Eye and Ear has found t...

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What Might Explain the Unhappiness Epidemic? WHAT MIGHT EXPLAIN THE UNHAPPINESS EPIDEMIC?

blog article

Aug 08, 2018

Although measures of teen and adult happiness dropped during the high unemployment rates of the Great Recession, it didn’t rebound when the economy started to improve. We’d all like to be a little happier. The problem is that much of what determines happiness is outside of our control. S...

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AI Is a New Must for Medical Software AI IS A NEW MUST FOR MEDICAL SOFTWARE

blog article

Aug 08, 2018

It appears that artificial intelligence is an apple of discord in disruptive technologies. On the one hand, even those who create new products based on AI or implement it across their internal processes, are worried. “Artificial intelligence and robots will kill many jobs,” predicts Jack...

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Cancer Cells vs Normal Cells CANCER CELLS VS NORMAL CELLS

blog article

Aug 08, 2018

Cancer is a complex genetic disease that is caused by specific changes to the genes in one cell or group of cells. These changes disrupt normal cell function – specifically affecting how a cell grows and divides. Cancer cells have more genetic changes compared to normal cells, however not all ...

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Link between appendicitis and allergies discovered LINK BETWEEN APPENDICITIS AND ALLERGIES DISCOVERED

blog article

Aug 07, 2018

Children with allergies have a lower risk of developing complicated appendicitis, according to a new study from Lund University and Skåne University Hospital in Sweden. The findings, now published in JAMA Pediatrics, could pave the way for new diagnostic tools in the future. "In a study o...

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Novel Approach Could Lead to Creation of New Thiophosphate-Based Nucleotide Drugs NOVEL APPROACH COULD LEAD TO CREATION OF NEW THIOPHOSPHATE-BASED NUCLEOTIDE DRUGS

blog article

Aug 07, 2018

Scientists at Scripps Research and Bristol-Myers Squibb have created a novel tool for precisely controlling the stereochemistry of thiophosphates, found in some promising new drugs that target genetic molecules and other disease targets. Called phosphorus-sulfur incorporation (PSI), the technology a...

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ADHD medications: Of all available drugs, methylphenidate should be first option for short-term treatment in children ADHD MEDICATIONS: OF ALL AVAILABLE DRUGS, METHYLPHENIDATE SHOULD BE FIRST OPTION FOR SHORT-TERM TREATMENT IN CHILDREN

blog article

Aug 07, 2018

Of the drugs available for attention-deficit hyperactivity disorder (ADHD), the most effective and safe for short-term treatment is methylphenidate for children, and amphetamines for adults, according to the most comprehensive evidence yet from a network meta-analysis and systematic review comparing...

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Learning More About Addiction Relapse LEARNING MORE ABOUT ADDICTION RELAPSE

blog article

Aug 06, 2018

Researchers studying cocaine addiction have managed to significantly reduce relapse rates in a preclinical model. To do so, a molecule called BDNF was delivered directly to a part of the brain that has a critical role in reward-seeking behavior, the nucleus accumbens, just before a rat model sought ...

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pH imbalance in astrocytes may lead to Alzheimer’s disease PH IMBALANCE IN ASTROCYTES MAY LEAD TO ALZHEIMER’S DISEASE

blog article

Aug 06, 2018

Researchers have identified that a simple pH imbalance in astrocytes could be the root of Alzheimer’s disease (AD). Scientists at Johns Hopkins Medicine said they have found new evidence in lab-grown mice brain cells that an imbalance in acid-alkaline chemistry in the endosomes may be a cause ...

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New drug may improve liver cancer therapy NEW DRUG MAY IMPROVE LIVER CANCER THERAPY

blog article

Aug 06, 2018

Researchers from many international institutions have teamed up to design a more effective drug for liver cancer therapy. Their compound may help improve survival rates and reduce adverse effects. The researcher working in the lab. If it is not caught early, this means that people who have been diag...

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Belly fat linked to cognitive decline BELLY FAT LINKED TO COGNITIVE DECLINE

blog article

Aug 06, 2018

In the largest study of its type, researchers conclude that having higher levels of belly fat in old age is correlated with a reduction in cognitive function. Dementias, including Alzheimer's, are a growing concern. As the average age of the population steadily rises, their prevalence increases....

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Agitation in dementia: Are drugs the best treatment? AGITATION IN DEMENTIA: ARE DRUGS THE BEST TREATMENT?

blog article

Aug 05, 2018

A common symptom among people with dementia is agitation, which can affect their and their carers' well-being. Dementia experts conducted a new study and found the most effective means of addressing agitation. In a paper that is now published in the journal International Psychogeriatrics, expert...

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Alzheimer’s Drug May Stop Disease If Used Symptoms Develop ALZHEIMER’S DRUG MAY STOP DISEASE IF USED SYMPTOMS DEVELOP

blog article

Aug 01, 2018

About 50 percent of people who reach the age of 85 will develop Alzheimer’s disease. Most will die within about five years of exhibiting the hallmark symptoms of the disease severe memory loss and a precipitous decline in cognitive function. But the molecular processes that lead to the disease...

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Artificial Intelligence System Designs Drugs From Scratch ARTIFICIAL INTELLIGENCE SYSTEM DESIGNS DRUGS FROM SCRATCH

blog article

Aug 01, 2018

An artificial-intelligence approach created at the University of North Carolina at Chapel Hill Eshelman School of Pharmacy can teach itself to design new drug molecules from scratch and has the potential to dramatically accelerate the design of new drug candidates. The system is called Reinforcement...

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New blood test may someday help guide the best treatment for aggressive prostate cancer NEW BLOOD TEST MAY SOMEDAY HELP GUIDE THE BEST TREATMENT FOR AGGRESSIVE PROSTATE CANCER

blog article

Aug 01, 2018

Tumors that spread, or metastasize, in the body shed cells into the blood that doctors can scrutinize for insights into what a patient’s cancer might do. Analyzing these so-called circulating tumor cell  (CTC) isn’t part of routine care yet, in part because they’re so har...

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The top 5 vaccine companies by 2017 revenue THE TOP 5 VACCINE COMPANIES BY 2017 REVENUE

blog article

Aug 01, 2018

Even in an industry dominated by a few huge companies, disruption happens sometimes and 2017 was one of those times. GlaxoSmithKline surpassed Merck to top the vaccine industry by sales, generating $7 billion compared to Merck's $6.5 billion. It stands to be a long-term switch, too; analysts pre...

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Effective Drug For Disorders of Copper Metabolism EFFECTIVE DRUG FOR DISORDERS OF COPPER METABOLISM

blog article

Aug 01, 2018

According to a paper in the Proceedings of the National Academy of Sciences, a research team led by Dr. Vishal Gohil of Texas A&M AgriLife Research in College Station has now offered more targeted treatment options for individuals with defects in copper metabolism. The paper reports on an invest...

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Can cell phone use cause ADHD? CAN CELL PHONE USE CAUSE ADHD?

blog article

Jul 31, 2018

Anyone who has spent any time around teens, and seen the way they often seem surgically attached to their phones, has likely wondered: is all that time on the phone affecting their brains? Researchers from California studied the digital media use of more than 2,500 high school students who did not h...

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Pill Approved For Endometriosis Treatment PILL APPROVED FOR ENDOMETRIOSIS TREATMENT

blog article

Jul 31, 2018

A first drug, by the name of Elagolix, to treat for endometriosis-related pain, has recently become approved by the US Food and Drug Administration. Endometriosis is caused by uterine tissue moving to another part of the body, usually around the pelvis. The pain, which affects one in ten young women...

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DNA For Drug Development? DNA FOR DRUG DEVELOPMENT?

blog article

Jul 31, 2018

Genetic data of individuals who were customers of DNA testing service for the purpose of understanding their ancestry and genetic history, such as the company 23andME, could now be utilized for the development of new drugs. 23andMe, the home DNA testing service, announced a 4-year deal with pharmace...

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Molecule deficiency may help diagnose severe depression MOLECULE DEFICIENCY MAY HELP DIAGNOSE SEVERE DEPRESSION

blog article

Jul 31, 2018

A new study, published in the journal PNAS, suggests that a diagnostic blood test for depression may soon be on the horizon. The new research shows that treatment-resistant depression is characterized by reduced blood levels of a specific molecule. According to the most recent estimates from the Nat...

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Pancreatic cancer: Cannabis compound may boost survival PANCREATIC CANCER: CANNABIS COMPOUND MAY BOOST SURVIVAL

blog article

Jul 31, 2018

Pancreatic cancer is a type of cancer that unfortunately has some of the lowest survival rates. A new study in mice suggests that one substance could help address this problem: cannabidiol, a naturally occurring cannabis compound. According to data from the National Cancer Institute (NCI), in the Un...

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What are the symptoms of late stage bladder cancer? WHAT ARE THE SYMPTOMS OF LATE STAGE BLADDER CANCER?

blog article

Jul 30, 2018

It is difficult to remove stage 4 cancer from the body entirely. The main aim of treatment, therefore, is to give people the best possible quality of life. Doctors use staging to help diagnose cancer, plan treatment, and explain a person's outlook clearly. There are four stages, which people oft...

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Mini-brains offer hope in search for new drugs for brain disorders MINI-BRAINS OFFER HOPE IN SEARCH FOR NEW DRUGS FOR BRAIN DISORDERS

blog article

Jul 30, 2018

Miniature brains grown in laboratory dishes could overcome some of the problems testing drugs on animals and help researchers identify new ways to treat very human, and incurable, conditions like Alzheimer’s disease and epilepsy. Most new drugs are developed and tested using mice as models. Ho...

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Gender Disparity in Post Heart Attack Treatment GENDER DISPARITY IN POST HEART ATTACK TREATMENT

blog article

Jul 29, 2018

Every 40 seconds, someone in the United States has a heart attack, with 790,000 Americans having a heart attack every year. After a heart attack, heart damage can affect heart rhythm, pumping action, and blood circulation. Damage can increase the risk of another heart attack or other conditions such...

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Parkinson PARKINSON'S GENE AFFECTS MORE PEOPLE THAN PREVIOUSLY THOUGHT

blog article

Jul 28, 2018

New research finds that a gene previously thought to affect only a small percentage of Parkinson's disease cases actually affects many more. The findings mean that treatments that are being developed for a small number of people may, in fact, benefit many more. Almost 1 million people in the Uni...

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Psoriasis: Mediterranean diet may slow disease progression PSORIASIS: MEDITERRANEAN DIET MAY SLOW DISEASE PROGRESSION

blog article

Jul 27, 2018

A new study suggests that adhering to a Mediterranean diet may relieve the severity of psoriasis and slow its progression. Mediterranean salad on blue background Psoriasis is a chronic inflammatory disease that affects about 6.7 million adults in the United States, according to recent estimates. Som...

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Side effects of painkillers are worse in Alzheimer SIDE EFFECTS OF PAINKILLERS ARE WORSE IN ALZHEIMER'S

blog article

Jul 27, 2018

A recent study demonstrates that pain relief drugs produce more pronounced side effects when taken by people with dementia. A second study uncovers why this might be the case. Older adult Alzheimer's care home. Dementia is a large and growing concern. Because it cannot be reversed, understanding...

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Cannabinoids for Dementia CANNABINOIDS FOR DEMENTIA

blog article

Jul 26, 2018

One area of interest in the last year, as medical cannabis moves into the mainstream, is the use of cannabinoids for the treatment of dementia.  To be clear, many of the scientists or providers looking to cannabis or cannabinoid products are really looking at treating the symptoms associated wi...

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New enzyme discovery may help improve drugs against cancer, diabetes and obesity NEW ENZYME DISCOVERY MAY HELP IMPROVE DRUGS AGAINST CANCER, DIABETES AND OBESITY

blog article

Jul 26, 2018

A new study reveals that several drugs for treating hematological cancers are less effective than expected in inhibiting a special enzyme. Researchers have also identified new lead compounds that could potentially improve existing treatments and pave the way for new drugs against diabetes and obesit...

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Adapting drug discovery to Artificial Intelligence ADAPTING DRUG DISCOVERY TO ARTIFICIAL INTELLIGENCE

blog article

Jul 25, 2018

There is a need and opportunity to explore new drug discovery approaches that harness immense datasets (public and private), which have been built upon the successes and failures of the past to guide in-silico approaches to new therapies. Advances in genetics and molecular biology have revealed pote...

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Fitness Trackers Helpful For Cancer Assessments FITNESS TRACKERS HELPFUL FOR CANCER ASSESSMENTS

blog article

Jul 25, 2018

A new study published in the journal Digital Medicine found that fitness trackers can be used as a valuable tool to only assess the quality of life but the daily functioning of cancer patients during the course of their treatment. The trackers, also called wearable activity monitors, include commerc...

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Super-resolution Microscope Provides Insight Into Alzheimer SUPER-RESOLUTION MICROSCOPE PROVIDES INSIGHT INTO ALZHEIMER'S PLAQUES

blog article

Jul 25, 2018

Alzheimer’s disease impacts around 200,000 Americans; it is the country’s sixth leading cause of death. The disease is thought to begin affecting the brain ten to twenty years before it can be diagnosed, which is a serious treatment challenge. New work by scientists at Purdue University ...

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Gottlieb Reshapes FDA to Elevate Centers, Streamline Policymaking GOTTLIEB RESHAPES FDA TO ELEVATE CENTERS, STREAMLINE POLICYMAKING

blog article

Jul 25, 2018

Most FDA commissioners look to leave their imprint on the agency by making structural changes that update the roles and functions of lead operations. After more than a year at the agency’s helm, Scott Gottlieb now proposes to flatten out FDA’s structure by having the Center directors rep...

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Liver Disease Deaths Are Up in Young Adults LIVER DISEASE DEATHS ARE UP IN YOUNG ADULTS

blog article

Jul 25, 2018

It’s a fact that overuse of alcohol can cause liver problems. Cirrhosis of the liver is often the result of long-term alcoholism, but a new study of the data shows that liver disease is increasing in young adults, a group not generally seen as at risk. During the years 1999-2016 deaths from ci...

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Can You Be Obese and Metabolically Healthy? CAN YOU BE OBESE AND METABOLICALLY HEALTHY?

blog article

Jul 24, 2018

Experts in the medical field, nutrition and fitness professionals and health educators all advise against the dangers of becoming overweight. They cite an "obesity epidemic," and it's true that health problems that can go along with obesity, such as hypertension, diabetes and cardiovas...

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Measles are on the Move MEASLES ARE ON THE MOVE

blog article

Jul 24, 2018

Measles is a highly contagious disease that used to be common in young children. Due to the development of vaccines, however, it’s been almost eradicated. Almost, because there are several communities in the United States that still experience a high rate of measles infections. Mostly the outb...

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Finding drugs that are safe to take while pregnant FINDING DRUGS THAT ARE SAFE TO TAKE WHILE PREGNANT

blog article

Jul 23, 2018

Expectant mothers often face a dilemma about whether to take medication when they fall ill due to fears it might harm their unborn baby, but new research is unraveling which drugs are safe to take during pregnancy. Pregnant women are excluded from trials of new medications for ethical reasons, which...

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Gestational Diabetes Increases Heart Disease Risk in Babies GESTATIONAL DIABETES INCREASES HEART DISEASE RISK IN BABIES

blog article

Jul 22, 2018

Gestational diabetes occurs in pregnant women who have high blood glucose (sugar) levels and have not previously had diabetes, usually around the 24th week. A 2014 study from the Center for Disease Control stated that gestational diabetes prevalence is as high as 9.2%. Gestational diabetes can affec...

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X-ray Images to Get Colors X-RAY IMAGES TO GET COLORS

blog article

Jul 20, 2018

In the near future, the X-ray images from your doctor's office will no longer be just black and white, at least that's what MARS Bioimaging Ltd, an imaging company based in New Zealand, hopes. Why are they so confident? A CERN (yes the organization that built the Large Hadron Collider)-devel...

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FDA Opens Door to Importing Scarce and Costly Drugs FDA OPENS DOOR TO IMPORTING SCARCE AND COSTLY DRUGS

blog article

Jul 20, 2018

For years, consumer advocates and state officials have pushed for access to less expensive prescription medicines available overseas, only to meet stiff resistance from FDA and government health authorities claiming that such action could bring unsafe and harmful products into the U.S. This oppositi...

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Treating Dementia With The Healing Waves Of Sound TREATING DEMENTIA WITH THE HEALING WAVES OF SOUND

blog article

Jul 20, 2018

Ultrasound waves applied to the whole brain improve cognitive dysfunction in mice with conditions simulating vascular dementia and Alzheimer’s disease. The research, conducted by scientists at Tohoku University in Japan, suggests that this type of therapy may also benefit humans.

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Stopping Structural Changes in Collagen may Prevent Lung Fibrosis STOPPING STRUCTURAL CHANGES IN COLLAGEN MAY PREVENT LUNG FIBROSIS

blog article

Jul 19, 2018

Lung fibrosis is a serious condition that thickens tissues in the lungs and makes it hard to breathe. It can be caused by a variety of environmental factors, including exposure to coal or grain dust. New work has shown that it may be possible to prevent the disease with a drug that can block structu...

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Immunotherapy Increases Survival of Melanoma Brain Metastases Patients IMMUNOTHERAPY INCREASES SURVIVAL OF MELANOMA BRAIN METASTASES PATIENTS

blog article

Jul 18, 2018

Melanoma, a form of skin cancer, accounts for about 1% of all skin cancer cases and a vast majority of skin cancer deaths. In Stage IV melanoma more than 60% of patients will develop brain metastases, which is difficult to treat and carries an overall survival of about 4-5 months. A recent study out...

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Fighting A Common Viral Infection In Kidney Transplant Patients FIGHTING A COMMON VIRAL INFECTION IN KIDNEY TRANSPLANT PATIENTS

blog article

Jul 18, 2018

Organ transplants save lives, but the immune-suppressing drugs needed to protect a transplant leave the recipient susceptible to potentially deadly infections like cytomegalovirus, or CMV. Now, a team of researchers is trying to predict which kidney transplant patients might be at risk. With the hel...

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CT Scans May Increase The Risk Of Brain Cancer CT SCANS MAY INCREASE THE RISK OF BRAIN CANCER

blog article

Jul 18, 2018

A new study in the Journal of the National Cancer Institute suggests that CT scans, commonly used in medical imaging, may increase the risk of brain tumors. The use of computed tomography (CT) scans has increased dramatically over the last two decades. CT scans greatly improve diagnostic capabilitie...

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Artificial Intelligence for Diagnosing and Typing Tumors ARTIFICIAL INTELLIGENCE FOR DIAGNOSING AND TYPING TUMORS

blog article

Jul 18, 2018

While most think of artificial intelligence (AI) as the stuff of sci-fi movies and futuristic novels, it actually has many medical applications. From brain-computer interfaces for patients who have been paralyzed by injury or disease to machine learning for prosthetic limbs, AI is a game changer in ...

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Powering up the Elderly POWERING UP THE ELDERLY'S IMMUNE SYSTEM

blog article

Jul 17, 2018

As we age our immune system weakens, leading to diseases such as influenza and pneumonia taking a toll on the elderly across the world. For people over 65 years of age infections are a leading cause of death, with an estimated 85% of all deaths from pneumonia in 2013 in the United States occurring i...

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Heart Failure Death Rates Higher in Females than Males HEART FAILURE DEATH RATES HIGHER IN FEMALES THAN MALES

blog article

Jul 17, 2018

Heart failure is a common cause of morbidity and mortality, despite progress made over the past 10 years, more than 6 million Americans live with heart failure, and over 900,000 new cases are diagnosed each year. There are known sex-based differences in risk factors, presentation, and management of ...

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Can the Keto Diet Make Cancer Treatment More Effective? CAN THE KETO DIET MAKE CANCER TREATMENT MORE EFFECTIVE?

blog article

Jul 17, 2018

It’s been said that “you are what you eat” but with so many diet plans and trends, it can be hard to choose. Paleo, keto, Mediterranean, and Nordic are all ways of eating that emphasize “clean eating” in different ways. Are they just trends or can they produce real...

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Solving pharma’s patient services paradox SOLVING PHARMA’S PATIENT SERVICES PARADOX

blog article

Jul 16, 2018

Pharma companies are expending considerable time, energy and money on developing services that are designed to support patients before, during and after treatment across therapeutic areas. But there’s a paradox at the heart of these patient services. Although patients want them and pharma comp...

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Omega-3-derived cannabinoid may stop cancer OMEGA-3-DERIVED CANNABINOID MAY STOP CANCER

blog article

Jul 16, 2018

Our bodies have an "endogenous," or "built-in," pain-killing system named after the cannabis plant: the endogenous cannabinoid system, otherwise known as the endocannabinoid system. Endocannabinoids are molecules that, together with their receptors, can be found throughout the bo...

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New Drug Target For Remyelination In Multiple Sclerosis NEW DRUG TARGET FOR REMYELINATION IN MULTIPLE SCLEROSIS

blog article

Jul 16, 2018

Remyelination, the spontaneous regeneration of the fatty insulator in the brain that keeps neurons communicating, has long been seen as crucial to the next big advance in treating multiple sclerosis (MS). However, a lack of understanding of how remyelination is stymied in the disease has hampered th...

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6 REASONS FOR DELAYED TREATMENT OF LYME DISEASE 6 REASONS FOR DELAYED TREATMENT OF LYME DISEASE

blog article

Jul 16, 2018

The key to killing Lyme disease bacteria successfully depends, in part, upon identifying the disease early on. Unfortunately, in all too many cases, individuals harboring the infection are not diagnosed early, which can lead to a delay in treatment and an increased risk of long-term complications.&n...

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Brain Disease and High Blood Pressure BRAIN DISEASE AND HIGH BLOOD PRESSURE

blog article

Jul 15, 2018

Research recently published in the medical journal, Neurology, found a link between high blood pressure and brain disease. As many as half of American adults have high blood pressure and do not even know it. High blood pressure, or hypertension, occurs when the force of blood flow through your blood...

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Nature Is Proving To Be Awesome Medicine For PTSD NATURE IS PROVING TO BE AWESOME MEDICINE FOR PTSD

blog article

Jul 13, 2018

The awe we feel in nature can dramatically reduce symptoms of post-traumatic stress disorder, according to UC Berkeley research that tracked psychological and physiological changes in war veterans and at-risk inner-city youth during white-water rafting trips. Psychologists tested nature’s heal...

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Scientists from UofA are changing the face of viral pathogen treatment SCIENTISTS FROM UOFA ARE CHANGING THE FACE OF VIRAL PATHOGEN TREATMENT

blog article

Jul 12, 2018

The University of Alberta appears to have hit the nail on the head yet again. With so much inspiring research coming out of this campus, it should come as no surprise that they have made a significant discovery that has the potential to treat viral pathogens such as the Zika virus and respiratory sy...

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Brain tumour chemotherapy now available to even more NHS patients BRAIN TUMOUR CHEMOTHERAPY NOW AVAILABLE TO EVEN MORE NHS PATIENTS

blog article

Jul 12, 2018

Science can be a painstakingly slow process. It can take years of tweaking, refining and rethinking to get solid, reliable evidence. And when it comes to developing new cancer treatments, the layers of research needed to go even deeper. Not only do scientists need to prove that a potential drug does...

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Exploiting the brain tumor environment to make better treatments EXPLOITING THE BRAIN TUMOR ENVIRONMENT TO MAKE BETTER TREATMENTS

blog article

Jul 12, 2018

Scientists are used to exploring unfamiliar territories. It’s thanks to centuries of these investigations that we understand most of the human body enough to fix things when they go wrong. Unfortunately, some parts of the body remain somewhat of a mystery. And the brain is perhaps one of the g...

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Solved protein puzzle opens door to new design for cancer drugs SOLVED PROTEIN PUZZLE OPENS DOOR TO NEW DESIGN FOR CANCER DRUGS

blog article

Jul 12, 2018

Researchers at Oregon State University have solved a longstanding puzzle concerning the design of molecular motors, paving the way toward new cancer therapies. Findings were published today in Current Biology. The research involved kinesins: tiny, protein-based motors that interact with microtubules...

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Innovative Development of Product Portfolio to Stimulate Production Sales of Vital Signs Monitoring Device INNOVATIVE DEVELOPMENT OF PRODUCT PORTFOLIO TO STIMULATE PRODUCTION SALES OF VITAL SIGNS MONITORING DEVICE

blog article

Jul 12, 2018

Low production cost has been significantly influencing the growth of the market for vital signs monitoring device across the globe. Apart from this, the major companies, as well as manufacturers, are working towards expanding the presence of their products with the help of several marketing activiti...

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Parkinson’s Foundation Prevalence Project Finds Number of People With Parkinson’s Severely Underestimated PARKINSON’S FOUNDATION PREVALENCE PROJECT FINDS NUMBER OF PEOPLE WITH PARKINSON’S SEVERELY UNDERESTIMATED

blog article

Jul 10, 2018

When a large population of people has a disease, like Parkinson’s disease (PD), it’s essential to have accurate numbers of how many people have the disease, where they live and why they have it. In our latest research initiative, we established the Parkinson’s Prevalence Project to...

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Pharmaceutical Industry to Stimulate Production Sales of Peptide Therapeutics PHARMACEUTICAL INDUSTRY TO STIMULATE PRODUCTION SALES OF PEPTIDE THERAPEUTICS

blog article

Jul 10, 2018

The rapid increase in FDI and rising healthcare expenditure has been driving the adoption of peptide therapeutics across the globe. Apart from this, growing prevalence of metabolic and cardiovascular disorders has been leading to a rapid increase in R&D activities with regards to usage of peptid...

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Cancer treatments should depend on the type of tumor CANCER TREATMENTS SHOULD DEPEND ON THE TYPE OF TUMOR

blog article

Jul 10, 2018

Traditionally, cancers have been treated according to the part of the body they are diagnosed in, like the breast, lungs, or bowel. But a new study from California’s Buck Institute for Research on Aging analyzed 33 cancer types and reclassified them into 28 molecular types, or ‘clus...

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Graphene in the fight against antimicrobial resistant bacteria GRAPHENE IN THE FIGHT AGAINST ANTIMICROBIAL RESISTANT BACTERIA

blog article

Jul 10, 2018

The overuse of antibiotics has led to antimicrobial resistant bacteria that threaten the lives of hundreds of millions. In the search for alternative ways to fight bacteria, a recent study published in Burns & Trauma turns to a composite of the world’s strongest known material, graphene, a...

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Engineering a Better Heart Valve ENGINEERING A BETTER HEART VALVE

blog article

Jul 09, 2018

Over 5 million Americans have heart valve disease (HVD), which can lead to heart failure, stroke, blood clots, and even death. HVD occurs when one or more of the four valves of the heart does not work properly, disrupting the flow of blood through your heart. The human heart has four valves: ao...

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Bioelectronic Medicine: Technology Targeting Molecular Mechanisms BIOELECTRONIC MEDICINE: TECHNOLOGY TARGETING MOLECULAR MECHANISMS

blog article

Jul 09, 2018

In this blog, Margot Puerta reports on the Bioelectronic Medicine: Technology Targeting Molecular Mechanisms symposium which took place in June. This three-day meeting had the aim of developing the field of bioelectronic medicine and brought together leading scientists and industry leaders from arou...

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Branded Drug Products to Significantly Stimulate Production Sales of Pharmaceuticals BRANDED DRUG PRODUCTS TO SIGNIFICANTLY STIMULATE PRODUCTION SALES OF PHARMACEUTICALS

blog article

Jul 06, 2018

The rapid increase in the cases related to non-communicable diseases and growing penetration of the health insurance companies, resulting in low treatment costs, thereby influencing healthcare providers for prescribing generic drugs have been contributing towards the substantial growth of Saudi Arab...

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Supporting the Development of Regenerative Medicines SUPPORTING THE DEVELOPMENT OF REGENERATIVE MEDICINES

blog article

Jul 06, 2018

Regenerative medicine can be defined as a branch of translational research which focuses on methods to regrow, repair or replace human cells, tissues or organs. This approach holds promise for revolutionary new cures for devastating conditions such as heart disease, diabetes, and cancer. We recently...

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Researchers Investigate Drug to Help Veterans With PTSD Sleep Better At Night RESEARCHERS INVESTIGATE DRUG TO HELP VETERANS WITH PTSD SLEEP BETTER AT NIGHT

blog article

Jul 06, 2018

A study into whether or not a new investigational drug could help veterans cope with trauma-related sleep disturbances is in its final phase of clinical research. Started this past January by Tonix Pharmaceuticals, the HONOR study is investigating the effectiveness of new medication intended to...

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BMC Medicine at Digestive Disease Week 2018 BMC MEDICINE AT DIGESTIVE DISEASE WEEK 2018

blog article

Jul 06, 2018

BMC Medicine joined Digestive Disease Week in 2018, the largest GI conference worldwide, held last June in Washington DC. Here we look at some of the highlights from the meeting. Attendance to the Digestive Disease Week 2018 gathering was marked by the impressive presence of around 32,000 parti...

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Digital Therapeutics: How to Ensure Quality in an Emerging Field DIGITAL THERAPEUTICS: HOW TO ENSURE QUALITY IN AN EMERGING FIELD

blog article

Jul 05, 2018

Imagine using the software on your phone or tablet to treat health conditions that, until now, could only be treated with medications. Now stop imagining, because, for some conditions, such as attention deficit disorder and substance dependency, it is already a reality. I’m talking about the n...

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Discovery of New Properties of an Anti-Tuberculosis Drug DISCOVERY OF NEW PROPERTIES OF AN ANTI-TUBERCULOSIS DRUG

blog article

Jul 04, 2018

Investigators at the University of Otago found novel properties of a new anti-tuberculosis drug which may inspire more new drugs to treat tuberculosis. Tuberculosis (TB), as well as TB resistant drugs, are responsible for about 1.7 million global deaths per year. In a collaboration, Greg Cook a prof...

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Increased Dose of Drug INCREASED DOSE OF DRUG 'RIFAMPIN' EFFECTIVE IN ELIMINATING TUBERCULOSIS BACTERIUM

blog article

Jul 04, 2018

According to a randomized controlled trial, a TB drug by the name ‘Rifampin’ was seen to effectively kill TB bacteria in sputum cultures when administered at an increased dose per day. In the publication "Efficacy and Safety of High-Dose Rifampin in Pulmonary Tuberculosis: A Randomi...

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Four steps to building an innovation culture in pharma FOUR STEPS TO BUILDING AN INNOVATION CULTURE IN PHARMA

blog article

Jul 04, 2018

The quest for innovation is a major driving force in pharma. From the discovery of therapeutic biologicals in the 1920s, such as Salvarsan and insulin, to the blockbuster drugs birthed in the 1990s, such as Lipitor and Humira, pharma has always been on a quest for novel, groundbreaking drug developm...

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5 Golden Rules For Effective (And Inspection Ready) OOS Investigations 5 GOLDEN RULES FOR EFFECTIVE (AND INSPECTION READY) OOS INVESTIGATIONS

blog article

Jul 04, 2018

The investigation of out of specification (OOS) results is a regulatory requirement in a GMP laboratory, and these investigations are intensively scrutinized by health authority inspectors. The purpose of this article is to provide five Golden Rules that will ensure investigations are both effective...

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Researcher uses HPV vaccine to treat patients with skin cancer RESEARCHER USES HPV VACCINE TO TREAT PATIENTS WITH SKIN CANCER

blog article

Jul 03, 2018

Squamous cell carcinoma is the second-most-common form of skin cancer. Evidence suggests the human papilloma virus plays a role in the development of some types of this skin cancer. Two years ago, a 97-year-old woman whose right leg was covered with squamous cell tumors went to see dermatologist Ann...

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Malaria eradication: tackling counterfeit and substandard drugs MALARIA ERADICATION: TACKLING COUNTERFEIT AND SUBSTANDARD DRUGS

blog article

Jul 02, 2018

Although malaria is beginning to be eradicated, it remains a global health issue and this is partially due to the existence of counterfeit and substandard drugs in the regions where malaria remains most prevalent: South East Asia and Africa. What is the extent of the problem in these areas, and what...

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New Regulations And Safety Complicate Drug Labeling NEW REGULATIONS AND SAFETY COMPLICATE DRUG LABELING

blog article

Jul 02, 2018

Multinational pharmaceutical companies have for decades manufactured drugs for global distribution. Nevertheless, the task of labeling is becoming increasingly difficult and time-consuming. With new labeling requirements that can vary by country and region, drug companies are forced to either develo...

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Adamis Pharma Sells Epinephrine Injector Rights to Novartis ADAMIS PHARMA SELLS EPINEPHRINE INJECTOR RIGHTS TO NOVARTIS

blog article

Jul 02, 2018

Adamis Pharmaceuticals is selling U.S. commercial rights to Symjepi, a competitor to Mylan’s EpiPen, to Novartis.Although financial details were not released, Novartis’ Sandoz division will pay Adamis an upfront fee and various performance-based milestone payments. Net profits in the U.S...

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Use of State Medicaid Inflation Rebates Could Discourage Drug Price Increases USE OF STATE MEDICAID INFLATION REBATES COULD DISCOURAGE DRUG PRICE INCREASES

blog article

Jun 28, 2018

List prices for prescription drugs set by the manufacturer before discounts and rebates have grown faster  than the rate of inflation.1  In 2015, average drug list prices increased by 6.4 percent, while general inflation only increased by 0.1 percent. 2 Although price concessions, primaril...

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How to achieve digital success in pharma’s communications HOW TO ACHIEVE DIGITAL SUCCESS IN PHARMA’S COMMUNICATIONS

blog article

Jun 27, 2018

Demystifying what digital means, empowering people to ‘think digitally’ and acting with confidence are game-changing factors for pharma communications according to Katrine Bach, the CEO of Anthill Agency. Bach, spoke to pharmaphorum for the Future Pharma issue of its Deep Dive digital ma...

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Sino-American Pharma Pros draws China, U.S. drugmakers to Philly SINO-AMERICAN PHARMA PROS DRAWS CHINA, U.S. DRUGMAKERS TO PHILLY

blog article

Jun 25, 2018

In a cheerful cacophony of start-up and recruiter pitches, emerging-science talks and investment-banking tips, laptop displays and card exchanges  in English and in Mandarin more than 1,000 Philadelphia-area scientists, pharma professionals, and people who want to do business with them  ja...

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Pharma Companies Secure About $250 Million in Financing Today PHARMA COMPANIES SECURE ABOUT $250 MILLION IN FINANCING TODAY

blog article

Jun 19, 2018

Venture capitalists are flexing their muscles today with the significant support of pharma and biotech companies. Approximately $250 million in financing has been secured to support various pipelines to address multiple concerns. Boston-based Decibel Therapeutics secured $55 million in a Series C fi...

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New Study Shows Drug War Sends Users to Dark Web NEW STUDY SHOWS DRUG WAR SENDS USERS TO DARK WEB

blog article

Jun 19, 2018

A new study published in the British journal BMJ says restricting the supply of illegal drugs forces users into black markets, where the drugs get more dangerous and more addictive. The authors of the study looked at the effect of the DEA's rescheduling of hydrocodone in 2014 from a schedule III...

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Global Halal Pharmaceuticals Market will reach 540 million US$ in 2023 with Double Digit CAGR GLOBAL HALAL PHARMACEUTICALS MARKET WILL REACH 540 MILLION US$ IN 2023 WITH DOUBLE DIGIT CAGR

blog article

Jun 18, 2018

A new market study, titled “Global Halal Pharmaceuticals Market 2018 by Manufacturers, Regions, Type and Application, Forecast to 2023”, has been featured on WiseGuyReports.Halal pharmaceuticals are those medicines that stringently adhere to Shariah law. More specifically, halal pharmace...

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Active Pharmaceutical Ingredients (API): Global Markets Estimated to Reach 154.7 billion by 2022 ACTIVE PHARMACEUTICAL INGREDIENTS (API): GLOBAL MARKETS ESTIMATED TO REACH 154.7 BILLION BY 2022

blog article

Jun 18, 2018

This report (Active Pharmaceutical Ingredients: Global Markets to 2022) covers an overview of the pharmaceutical industry landscape and active pharmaceutical ingredients (API), along with the current trends and dynamics shaping the API market landscape. API sourcing trends and regulatory guidelines ...

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How Correctional Facilities Could Lower Drug Prices HOW CORRECTIONAL FACILITIES COULD LOWER DRUG PRICES

blog article

Jun 14, 2018

State and local correctional facilities, including prisons and jails, are required to provide health care to incarcerated adults.1 Drug spending has an outsize impact on correctional health care budgets: Of the states that report drug spending, the majority spend more than 15 percent of their health...

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North Carolina Bill Would Make Prescription Records Available to Police Without a Warrant NORTH CAROLINA BILL WOULD MAKE PRESCRIPTION RECORDS AVAILABLE TO POLICE WITHOUT A WARRANT

blog article

Jun 12, 2018

America’s opioid epidemic is a grave public health issue, one that experts and a growing national consensus say we need to approach with solutions based in science and treatment. Unfortunately, some lawmakers haven’t gotten the memo and want to continue with the failed and inhumane strat...

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Psychedelic drugs could inspire new medications to treat depression and anxiety PSYCHEDELIC DRUGS COULD INSPIRE NEW MEDICATIONS TO TREAT DEPRESSION AND ANXIETY

blog article

Jun 12, 2018

Drugs like LSD help neurons reach out to each other, a promising path for pharmaceutical development. In a new study, researchers looked at a range of psychedelic drugs and their effects on neurons in the petri dish and tested one drug in rats. They found that these drugs help neurons branch out and...

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How pharma hides data about farm antibiotic use HOW PHARMA HIDES DATA ABOUT FARM ANTIBIOTIC USE

blog article

Jun 11, 2018

ON Wednesday  last week, the non-profit Natural Resources Defense  Council revealed that pig herds in the United States receive almost as many antibiotics as people in this country do. That’s bad news, especially since most of the pigs receiving antibiotics aren’t sick, but ins...

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Aspirin for prevention: A look at the potential benefits and risks ASPIRIN FOR PREVENTION: A LOOK AT THE POTENTIAL BENEFITS AND RISKS

blog article

Jun 07, 2018

When my doctor first asked me to take aspirin, I wasn’t so sure I needed it. Since the 1980s, aspirin has a proven record of preventing second heart attacks and strokes, but its use in people without these problems was and remains a source of confusion for both doctors and patients. Why take a...

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Nigeria’s drug makers upgrade factories to push for more WHO certifications NIGERIA’S DRUG MAKERS UPGRADE FACTORIES TO PUSH FOR MORE WHO CERTIFICATIONS

blog article

Jun 05, 2018

The quest to obtain the World Health Organisation (WHO)’s prequalification is pushing more local pharmaceutical companies into upgrading their machinery and factories, with a number of them investing in new facilities. The WHO prequalification enables a pharmaceutical company to participate in...

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Study finds rare gain for tough-to-treat pancreatic cancer STUDY FINDS RARE GAIN FOR TOUGH-TO-TREAT PANCREATIC CANCER

blog article

Jun 04, 2018

Patients with pancreatic cancer that hadn’t spread lived substantially longer on a four-drug combo than on a single standard cancer drug, a rare advance for a tough-to-treat disease, researchers reported Monday. The results indicate the powerful chemotherapy treatment known as folfirinox will ...

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Blockchain to Shape Next Generation Healthcare Supply Chains BLOCKCHAIN TO SHAPE NEXT GENERATION HEALTHCARE SUPPLY CHAINS

blog article

Jun 01, 2018

Blockchain technology will play a key role in supporting supply chain transformation in the healthcare sector by helping to reduce fraud and better manage quality in the manufacturing and distribution of pharmaceutical products, according to leading data and analytics company GlobalData.Counterfeiti...

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Three charged over dangerous drugs, Arundel THREE CHARGED OVER DANGEROUS DRUGS, ARUNDEL

blog article

Jun 01, 2018

Police have charged three people following the alleged discovery of dangerous drugs at Arundel this morning.It is alleged that around 7.20am, officers from the Rapid Action Patrol group executed a search warrant at a private residence on Portreeves Place, where they allegedly located methamphetamine...

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Madrigal pharma more than doubles after liver drug study success MADRIGAL PHARMA MORE THAN DOUBLES AFTER LIVER DRUG STUDY SUCCESS

blog article

May 31, 2018

Madrigal Pharmaceuticals Inc’s shares more than doubled after mid-stage trial data showed its lead drug reduced liver fat in patients with fatty liver disease, placing it ahead of larger rivals to tap into a potential market worth $30 billion.Often dubbed the “silent disease” becau...

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Native American Tribes, State and Local Governments Sue Pharmaceutical Companies Over Opioid Abuse Crisis NATIVE AMERICAN TRIBES, STATE AND LOCAL GOVERNMENTS SUE PHARMACEUTICAL COMPANIES OVER OPIOID ABUSE CRISIS

blog article

May 30, 2018

In a desperate attempt to fill their empty coffers and convince voters they are doing something -- anything -- to stop the current opioid abuse epidemic, hundreds of cities, counties, Native American tribes and hospitals are suing pharmaceutical companies for their role in the opioid abuse crisis.&n...

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Decoding the deadly Nipah virus DECODING THE DEADLY NIPAH VIRUS

blog article

May 28, 2018

A virus named after Kampung Sungai Nipah, a village in Malaysia, where it was first discovered in 1998-99. The virus, that eventually killed 105 people in Malaysia, was first suspected to be Japanese encephalitis (JE) which, like the Nipah virus, induces brain inflammation. According to a paper by D...

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Oncology drives major pharma deals while immuno-oncology patent activity soars ONCOLOGY DRIVES MAJOR PHARMA DEALS WHILE IMMUNO-ONCOLOGY PATENT ACTIVITY SOARS

blog article

May 23, 2018

Cancer immunotherapy is an exciting, relatively new therapy that treats cancer by unleashing the power of the immune system. It has been hailed as one of the most promising advances in the treatment of cancer in recent times. Immuno-oncology research is growing at a rapid pace and for the last three...

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How Big Pharma forces us to buy drugs instead of cannabis HOW BIG PHARMA FORCES US TO BUY DRUGS INSTEAD OF CANNABIS

blog article

May 23, 2018

Simply put, Big Pharma has been a long time opponent of legalizing medical marijuana as it threatens to ruin its business and drop the market cap for pharmaceutical drug companies.Even though medical cannabis has been legalized in more than half of the US states, all of Canada and in Mexico, prices ...

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Doctors who got free lunches from Big Pharma were more likely to prescribe opioids DOCTORS WHO GOT FREE LUNCHES FROM BIG PHARMA WERE MORE LIKELY TO PRESCRIBE OPIOIDS

blog article

May 22, 2018

Is a life worth a free meal? This might not exactly be the way the question is phrased in a research letter published in JAMA, yet that’s the underlying assumption you’re left with. After reviewing two years of data on prescription rates, it appears doctors were influenced by free meals ...

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Vermont Drug Importation Program Is Not Illegal VERMONT DRUG IMPORTATION PROGRAM IS NOT ILLEGAL

blog article

May 18, 2018

In its wisdom and activist spirit, Vermont has a new law on the books allowing for the wholesale importation of FDA-approved drugs from authorized wholesalers in Canada. Canadian wholesale pharmacies sell many brand-name drugs at much lower costs than their U.S. counterparts. This could help patient...

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Big Pharma Bribes Linked To Doctors Prescribing Large Quantities Of Opioids BIG PHARMA BRIBES LINKED TO DOCTORS PRESCRIBING LARGE QUANTITIES OF OPIOIDS

blog article

May 15, 2018

(DCNF) Major pharmaceutical companies heavily influenced doctors to prescribe high rates of opioid medications with lavish spending, new research suggests. Doctors, who received paid speaking gigs, free lunches and branded merchandise from drug makers, were linked to much high rates of opioid prescr...

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Can Hot Dogs Influence the Drugs a Doctor Prescribes? CAN HOT DOGS INFLUENCE THE DRUGS A DOCTOR PRESCRIBES?

blog article

May 15, 2018

A stroll around the exhibit area of the American Psychiatric Association Conference demonstrates how pharma marketing can influence the prescribing patterns of doctors — possibly at the expense of patients' health. If you were walking around the exhibit halls of the Jacob K. Javits Convent...

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Trump Drug Pricing Plan Outlines Rule Changes Pharma Can Live With TRUMP DRUG PRICING PLAN OUTLINES RULE CHANGES PHARMA CAN LIVE WITH

blog article

May 14, 2018

After months of expectations and repeated delays, President Donald Trump formally announced his strategy for making prescription medicines more affordable and accessible in the U.S. Trump promised to take on the “tangled web of special interests” that drive up drug prices, noting the hig...

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Jeff Sessions decision to re-up in the drug war won JEFF SESSIONS DECISION TO RE-UP IN THE DRUG WAR WON'T WORK

blog article

May 14, 2018

Attorney General Jeff Sessions’ newly issued sentencing directive to federal prosecutors, revoking the Obama-era Smart on Crime Initiative, is a devastating revival of the War on Drugs. The repercussions of this move will undoubtedly reverse the decline in the federal prison population of rece...

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Big Pharma funds opioid training. What could go wrong? BIG PHARMA FUNDS OPIOID TRAINING. WHAT COULD GO WRONG?

blog article

May 12, 2018

The ‘Global and Chinese Nasal Drug Delivery Technology Industry, 2013-2023 Market Research Report’ is a professional and in-depth study on the current state of the global Nasal Drug Delivery Technology industry with a focus on the Chinese market. The report provides key statistics on the...

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Trump Speaks About Proposal to Lower U.S. Drug Prices TRUMP SPEAKS ABOUT PROPOSAL TO LOWER U.S. DRUG PRICES

blog article

May 11, 2018

President Donald Trump is expected to unveil a proposal today to bring down U.S. drug prices. The blueprint, called American Patients First, is meant to increase pharmaceutical competition and lower patients’ out-of-pocket costs. Trump is scheduled to speak about the plan's details at 2 p....

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President set to outline drug pricing plan: how far will it go? PRESIDENT SET TO OUTLINE DRUG PRICING PLAN: HOW FAR WILL IT GO?

blog article

May 10, 2018

Tomorrow at 2 p.m., EST,  the President is scheduled to deliver a long-awaited drug pricing strategy speech to put “America’s patients first.”  While details of the speech have been closely held, it is anticipated that it will  discuss a “comprehensive strategy...

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Local pharmaceuticals innovate new drugs amid codeine crisis LOCAL PHARMACEUTICALS INNOVATE NEW DRUGS AMID CODEINE CRISIS

blog article

May 10, 2018

It was an irony of sorts that while the National Agency for Food and Drug Administration and Control (NAFDAC) was announcing a ban on three pharmaceutical firms over codeine-containing syrup on Tuesday, an Anambra State-based drug maker, Juhel Nigeria, was getting set to unveil its new Oxytocin inje...

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FG codeine ban, Emzor Pharma closure a knee jerk response – Experts FG CODEINE BAN, EMZOR PHARMA CLOSURE A KNEE JERK RESPONSE – EXPERTS

blog article

May 09, 2018

The recent ban on codeine-containing cough syrup by the Federal Government, shutting down Emzor Pharmaceuticals Ind. Ltd., Peace Standard Pharmaceutical Limited and Bioraj Pharmaceutical Limited is a knee jerk response to the drug abuse problem experts have said. The ban is echoing in the public spa...

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Contraceptive Pills Market 2018 Size and Growth Factors Research with Topmost Leading Vendors CONTRACEPTIVE PILLS MARKET 2018 SIZE AND GROWTH FACTORS RESEARCH WITH TOPMOST LEADING VENDORS

blog article

May 09, 2018

Anti-conception medication pills which are also called as oral contraceptive pills are a kind of female hormonal anti-conception medication technique and are extremely viable at avoiding pregnancy. The Pills are small tablets that a patient swallow every day. Most pills contain two sorts of manufact...

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Weak Sector Earnings Dragging Pharmaceutical ETFs Down WEAK SECTOR EARNINGS DRAGGING PHARMACEUTICAL ETFS DOWN

blog article

May 07, 2018

From Zacks: Total earnings for 83.1% of the total healthcare market capitalization are up 14.7% on revenue growth of 8.1%. The growth rates seem unimpressive when compared with some of the other sectors. Earnings and revenue beat ratios of 88.9% and 75%, respectively, are also not great either. Amon...

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Drug Take Back Day Sets State Record DRUG TAKE BACK DAY SETS STATE RECORD

blog article

May 04, 2018

The Manchester Police Department collected 33 pounds of medication for disposal at the Drug Take Back Day Saturday at Brehme Drug.  Residents of the state disposed of 12,333 pounds of old or unused prescription drugs during Saturday’s event. According to the Governor’s Office of Dru...

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How synthetic opioids can radically change global illegal drug markets and foreign policy HOW SYNTHETIC OPIOIDS CAN RADICALLY CHANGE GLOBAL ILLEGAL DRUG MARKETS AND FOREIGN POLICY

blog article

Apr 30, 2018

Replacing drugs derived from plants (e.g., heroin, cannabis) with synthetic analogues (e.g., fentanyl, spice/K2) could be the most disruptive innovation in the history of the international drug trade. As we explain in the current issue of Foreign Affairs, it may also alter international relations an...

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blolg - pharma test BLOLG - PHARMA TEST

blog article

Apr 30, 2018

This article is part of a series on Corporate law Society.svg By jurisdiction[show] General corporate forms[show] Corporate forms by jurisdiction[show] Doctrines[show] Related areas[show] Company portal Law portal v t e A company, abbreviated as co., is a legal entity made up of an association of pe...

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International Drug Price Comparisons for Medicare Part D Medications INTERNATIONAL DRUG PRICE COMPARISONS FOR MEDICARE PART D MEDICATIONS

blog article

Apr 26, 2018

Senator Claire McCaskill (D-MO) requested an investigation into drug price increases among the Medicare Part D program’s 20 most widely-prescribed medications over a five-year period. The investigation, conducted by the Senate Committee on Homeland Security and Government Affairs, found that a...

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Orexigen opens bidding process, selling itself for $75 million OREXIGEN OPENS BIDDING PROCESS, SELLING ITSELF FOR $75 MILLION

blog article

Apr 25, 2018

To continue reading this article and to access exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space you need to be logged into the site and have an active subscription or trial subscription.  Please login or subscribe in ...

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Pharmaceuticals Grade Sodium Bicarbonate Market: North America to Remain at Leading Position through 2027 PHARMACEUTICALS GRADE SODIUM BICARBONATE MARKET: NORTH AMERICA TO REMAIN AT LEADING POSITION THROUGH 2027

blog article

Apr 23, 2018

Sodium bicarbonate is usually utilized as an active pharmaceutical excipient and component, in pharmaceutical industry. It is fundamentally employed for the treatment of cardiac arrest, circulatory insufficiency, and hemodialysis. Future Market Insights has published a report on global pharmaceutica...

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How to talk to your doctor about medication HOW TO TALK TO YOUR DOCTOR ABOUT MEDICATION

blog article

Apr 23, 2018

Pharmacology has changed the practice of medicine. Scientists are continually working on new and better drugs to manage medical conditions, from high blood pressure to autoimmune diseases to cancer. The mechanism of a drug how it actually works on the condition it is mean to treat is one important f...

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Regulating Self-Driving Cars Like Pharmaceuticals Is a Really Stupid Idea REGULATING SELF-DRIVING CARS LIKE PHARMACEUTICALS IS A REALLY STUPID IDEA

blog article

Apr 18, 2018

After Elaine Herzberg became the first person killed by a self-driving car, the proponents of government control quickly urged greater federal regulation of the nascent industry. But such regulation would not enhance safety. Most likely, it would kill more people, by delaying the deployment of safer...

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Patient-centric networks at the heart of pharmaceutical supply chain management: Lessons from LogiPharma Europe 2018 PATIENT-CENTRIC NETWORKS AT THE HEART OF PHARMACEUTICAL SUPPLY CHAIN MANAGEMENT: LESSONS FROM LOGIPHARMA EUROPE 2018

blog article

Apr 18, 2018

In early April I attended the LogiPharma Europe 2018 conference in Montreux, Switzerland, an event that attracted more than 800 attendees, including practitioners and executives from pharma and medical device industries, along with software vendors and many service providers. Here are some key takea...

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Attorney General Sessions Proposes An Even More Destructive Opioid Policy ATTORNEY GENERAL SESSIONS PROPOSES AN EVEN MORE DESTRUCTIVE OPIOID POLICY

blog article

Apr 18, 2018

Speaking to a group of law enforcement officials in Raleigh, NC yesterday, Attorney General Jeff Sessions announced proposed rule changes to the way the Drug Enforcement Administration sets quotas on the manufacturing of opioids. The DEA now presumes to be able to divine the likelihood a particular ...

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UK drug discovery startup BenevolentAI raises $115M UK DRUG DISCOVERY STARTUP BENEVOLENTAI RAISES $115M

blog article

Apr 18, 2018

U.K.-based artificial intelligence company BenevolentAI Ltd. today announced the completion of a $115 million funding round that values the London startup at a cool $2 billion. The round, said to be one of the largest ever in the AI pharmaceutical sector, was led by BevenolentAI’s existing bac...

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Multi-material shipping container for pharmaceuticals MULTI-MATERIAL SHIPPING CONTAINER FOR PHARMACEUTICALS

blog article

Apr 17, 2018

Containerization, or massing smaller pieces of cargo together in a single, larger container, was first practiced for shipping of coal in 17th Century England. The idea has evolved since into the now-ubiquitous stackable intermodal containers seen on container ships, trains and trucks. Likewise, the ...

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Alliance pharma sells chinese business for £2.9 million ALLIANCE PHARMA SELLS CHINESE BUSINESS FOR £2.9 MILLION

blog article

Apr 17, 2018

Wiltshire-based Alliance Pharma, the specialty pharmaceutical group, have announced that it has agreed to sell its 60% interest in non-core Unigreg Limited to its joint venture partner, Pacific Glory Development Limited, for £2.9 million. Unigreg owns the rights to Forceval, a micro-nutrient s...

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Amazon vs. Walmart: Can Corporate America Lower Drug Prices? AMAZON VS. WALMART: CAN CORPORATE AMERICA LOWER DRUG PRICES?

blog article

Apr 10, 2018

The former statement comes as no surprise. Americans spend $450 billion on medications annually, a figure projected to reach as much as $610 billion by 2021.(www.cnbc.com) Every family physician knows patients who have cut their meds in half, skipped doses or simply forgone medications because they ...

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Pharma firms could report weak numbers PHARMA FIRMS COULD REPORT WEAK NUMBERS

blog article

Apr 09, 2018

The troubled pharma sector is expected to report weak Q4FY18 numbers, with their profit after tax (PAT) likely to decline by 9 per cent year-on-year (YoY) and rupee appreciation may put pressure on their realisations, industry analysts said. Edelweiss research analyst Deepak Malik said the firm expe...

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Rewriting Pharma’s Talent Blueprint REWRITING PHARMA’S TALENT BLUEPRINT

blog article

Apr 09, 2018

If you are searching for the best current example of the future career path of pharmaceutical executives, look no further than the April 2017 appointment of GlaxoSmithKline’s CEO Emma Walmsley. While she has been with GSK since 2010, Walmsley joined the pharma giant after 17 years with L&rsquo...

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Trading Big Pharma for Small Startup TRADING BIG PHARMA FOR SMALL STARTUP

blog article

Apr 08, 2018

After speaking with at least a half-dozen C-suite level executives who made the leap from big pharma to lesser-known startup or biotech companies, it’s very clear that there is something deep down in their personalities that propelled them to make the move. Some of them were at the top of thei...

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How Blockchain Can Improve the Pharma Manufacturing Supply Chain HOW BLOCKCHAIN CAN IMPROVE THE PHARMA MANUFACTURING SUPPLY CHAIN

blog article

Apr 06, 2018

The entire pharmaceutical industry has been booming, from the manufacturing of clinical trial materials to support research studies to the regulated medicines on the pharmacy shelves. It has been one of the top industry performers of the past three decades. By maintaining the highest safety and qual...

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Rumored startup acquisition would boost Walmart RUMORED STARTUP ACQUISITION WOULD BOOST WALMART'S PHARMACEUTICAL PRESENCE

blog article

Apr 04, 2018

The retail giant is said to be in talks with online startup PillPack, which pre-sorts pills into date- and time-stamped packets for patients who take multiple drugs. Walmart Inc. is in early talks about a deal for closely held PillPack, an online startup that could help grow the retail giant’s...

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Corvus Pharmaceuticals: A New Immunotherapy Player CORVUS PHARMACEUTICALS: A NEW IMMUNOTHERAPY PLAYER

blog article

Apr 04, 2018

The immune checkpoints are signaling molecules that act to shut down or block an immune response. In a healthy person, this mechanism is a "safety" feature allowing cessation of the immune response once it has performed its task. Cytotoxic T Lymphocyte Antigen 4 (CTLA‐4) and programmed Dea...

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New York politician (and former Big Pharma member) wants to ban vaping and walking NEW YORK POLITICIAN (AND FORMER BIG PHARMA MEMBER) WANTS TO BAN VAPING AND WALKING

blog article

Apr 03, 2018

Just when you think you’ve heard everything, news comes out of New York that a certain democratic member of city council wants to make vaping and walking on sidewalks illegal.  The actual bill is currently geared towards making smoking illegal, but one can safely assume that vaping will a...

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Add pharmaceuticals to the list of trade complaints ADD PHARMACEUTICALS TO THE LIST OF TRADE COMPLAINTS

blog article

Mar 28, 2018

International trade is in the news these days, almost on par with the media pumping the tale of porno star Stormy Daniels.  Even so, there's still an aspect of trade that gets far too little attention.  This is surprising, given that it adversely affects millions of Americans.  It...

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Pharma Ocean Freight Enters New Waters PHARMA OCEAN FREIGHT ENTERS NEW WATERS

blog article

Mar 28, 2018

A new integrated ocean freight program for pharmaceuticals aims at a new approach to pharma-logistics fulfillment. The Posiedon project seeks to harness the collective knowledge of the supply chain to drive innovation, efficiencies, and safety and save money. “It’s the difference between...

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Why Are Pharmaceutical Drugs So Expensive? Sen. McCaskill’s Report Misses Larger Picture WHY ARE PHARMACEUTICAL DRUGS SO EXPENSIVE? SEN. MCCASKILL’S REPORT MISSES LARGER PICTURE

blog article

Mar 28, 2018

On Monday, Senator Claire McCaskill’s office released a report examining overall price increases for the top 20 brand-name prescription drugs in the United States. According to the report, the price for these drugs increased an average of 12 percent every year for five years, more than 10 time...

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Empty Capsules Market to Ride on Flourishing Pharmaceuticals Industry EMPTY CAPSULES MARKET TO RIDE ON FLOURISHING PHARMACEUTICALS INDUSTRY

blog article

Mar 27, 2018

A report recently added by Transparency Market Research to its repository, titled, “Empty Capsules Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016–2023,” delves deep into the market which forms a crucial part of the pharmaceutical industry wo...

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How Can The Pharma Industry Help The Homeless? HOW CAN THE PHARMA INDUSTRY HELP THE HOMELESS?

blog article

Mar 23, 2018

In January I published, “Can JPM And BTS Make A Bigger Difference?” This was part one of a four-part blog series on my experience of attending this year’s J.P. Morgan Healthcare (JPM) and Biotech Showcase (BTS) conferences in San Francisco. In this particular blog, I wrote about th...

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Getting to know the chief pharmaceutical officer GETTING TO KNOW THE CHIEF PHARMACEUTICAL OFFICER'S CLINICAL FELLOWS JUSTIN, TAHMINA AND KHOLA

blog article

Mar 22, 2018

I am currently based at Bupa and work alongside two fellows from the National Medical Director’s Clinical Fellow Scheme. Prior to the scheme I gained experience in various pharmacy specialities within secondary care. I am primarily a surgical specialist pharmacist although I have undertaken ro...

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Bayer looks to leverage AI across the pharma value chain BAYER LOOKS TO LEVERAGE AI ACROSS THE PHARMA VALUE CHAIN

blog article

Mar 21, 2018

Bayer has already shown more than a passing interest in artificial intelligence through its digital accelerator programme Grants4Apps, but the company’s use of the technology looks to be more wide-ranging and deep-seated than that. Talking to journalists after the company’s Financial New...

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Treatment for Post-Surgical Nausea and Vomiting TREATMENT FOR POST-SURGICAL NAUSEA AND VOMITING

blog article

Mar 20, 2018

Amisulpride, a drug developed for the treatment of schizophrenia, was studied to be effective in preventing postoperative nausea and vomiting (PONV). The drug was seen to decrease the development of PONV when used in combination with a standard anti-nausea treatment; administered intraoperatively.

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The THE 'TRIPLE PILL': A NEW BLOOD PRESSURE TREATMENT

blog article

Mar 16, 2018

Even though there exists an abundance of blood pressure-lowering drugs, high blood pressure persists to be a health concern not only in the US but globally. Blood pressure can lead to heart attacks, kidney issues, as well as stroke; therefore, treating blood pressure is a crucial priority. On a glob...

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The power of precision medicine in cancer drug discovery and treatment THE POWER OF PRECISION MEDICINE IN CANCER DRUG DISCOVERY AND TREATMENT

blog article

Mar 14, 2018

Precision medicine is at the forefront of innovative cancer treatment, targeting specific changes in a patient’s tumour DNA to treat, or even maybe one day prevent, the disease while also taking into account genetic variations between individuals, along with environmental and lifestyle factors...

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Latest edition of Pharmaceutical Trademarks: A Global Guide now available LATEST EDITION OF PHARMACEUTICAL TRADEMARKS: A GLOBAL GUIDE NOW AVAILABLE

blog article

Mar 13, 2018

The seventh edition of Pharmaceutical Trademarks: A Global Guide, which provides trademark professionals with comprehensive guidance on the key issues involved in the protection, enforcement and marketing of pharmaceutical brands, is now available to view online. In its Pharma 2020 series, PwC estim...

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Pond Virus Cures Patient POND VIRUS CURES PATIENT'S ANTIBIOTIC-RESISTANT INFECTION

blog article

Mar 12, 2018

An 80-year old doctor was stricken by a deadly bacterial infection, and doctors stopped it with a virus taken from a pond in Connecticut. In what seems like the plot of a movie, the virus, a type of bacteriophage, had been found to have an affinity for Pseudomonas aeruginosa. That same bacterium was...

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Treating Hearing Loss: A Set of Inhibiting Drugs Provide Promising Results TREATING HEARING LOSS: A SET OF INHIBITING DRUGS PROVIDE PROMISING RESULTS

blog article

Mar 12, 2018

Our inner ears contain roughly 30,000 tiny hair cells that work to detect sound waves as well as to translate these waves into nerve signals. The nerve signals allow us to hear everyday sounds from speeches to music. However, any damage to the hair cells leads to hearing loss, a condition that affec...

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New Report Links Opioid Prescriptions to Pharmaceutical Payouts to Doctors NEW REPORT LINKS OPIOID PRESCRIPTIONS TO PHARMACEUTICAL PAYOUTS TO DOCTORS

blog article

Mar 11, 2018

President Donald Trump has called for the death penalty for drug dealers. But would that include doctors and pharmaceutical company CEOs? A new report by CNN based on analysis conducted with Harvard researchers has found a direct link between opioid manufacturers and large payouts to doctors who pre...

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Some ibuprofen users exceed daily NSAID dose limit SOME IBUPROFEN USERS EXCEED DAILY NSAID DOSE LIMIT

blog article

Mar 09, 2018

Exceeding the recommended daily dose of non-steroidal anti-inflammatory drugs (NSAIDs) can have considerable side effects, such as increased risk of gastrointestinal bleeding. However, limited data are available on how often the daily limit is exceeded. In Pharmacoepidemiology & Drug Safety (26 ...

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BenevolentAI claims AI first with new Cambridge facility BENEVOLENTAI CLAIMS AI FIRST WITH NEW CAMBRIDGE FACILITY

blog article

Mar 08, 2018

The firm says its new facility on the Babraham Research Campus will “radically reduce the time it takes for drug candidates to enter clinical testing”. Ken Mulvany, founder and chairman of BenevolentAI, said: "We have built an artificial intelligence technology that can read and und...

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Handling Potent Active Pharmaceutical Ingredients HANDLING POTENT ACTIVE PHARMACEUTICAL INGREDIENTS

blog article

Mar 06, 2018

The World Health Organization (WHO) defines an active pharmaceutical ingredient (API) as: “Any substance or combination of substances used in a finished pharmaceutical product (FPP), intended to furnish pharmacological activity or to otherwise have direct effect in the diagnosis, cure, mitigat...

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Could a pharma company shun sales reps and be successful? COULD A PHARMA COMPANY SHUN SALES REPS AND BE SUCCESSFUL?

blog article

Feb 26, 2018

Matt Lowe, pharma agency veteran and founder (just this week) of healthtech agency performance.io, believes that such a company, relying heavily on search and performance marketing, may be a possiblity in the next few years (albeit once somebody has the courage to take the leap). I spoke to Lowe abo...

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What Happened to the Plans for a Smart Contact Lens for Diabetics? WHAT HAPPENED TO THE PLANS FOR A SMART CONTACT LENS FOR DIABETICS?

blog article

Jan 25, 2018

Originally projected to be on the market by 2020, excitement about the contact lens to measure glucose levels from Novartis and Google has waned. Why? In 2016, smart wearables growth was steady but a recent study predicts that the market will pick up this year introducing innovative products to the ...

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Yet More Good News for GW Pharma’s Cannabinoid Drug Against Epilepsy YET MORE GOOD NEWS FOR GW PHARMA’S CANNABINOID DRUG AGAINST EPILEPSY

blog article

Jan 25, 2018

GW Pharmaceuticals has achieved encouraging Phase III results for Epidiolex, which have been published in leading scientific journal, The Lancet. The company’s lead candidate is being developed for the treatment of epilepsy – a condition characterized by the abnormal firing of neurons in...

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Big Pharma Suppliers Are Dumping Toxic Waste in the Environment, Investor Alleges BIG PHARMA SUPPLIERS ARE DUMPING TOXIC WASTE IN THE ENVIRONMENT, INVESTOR ALLEGES

blog article

Jan 24, 2018

A Swedish investor is pressing the world’s biggest drug companies to be transparent about their supply chains, after it alleged that some suppliers to those firms were dumping toxic waste into the environment. Nordea Asset Management, the investment arm of the Nordic region’s largest ban...

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Biotech and Pharma Boost R&D and Slow Sales to Beat Antibiotic Resistance BIOTECH AND PHARMA BOOST R&D AND SLOW SALES TO BEAT ANTIBIOTIC RESISTANCE

blog article

Jan 24, 2018

Antibiotics are becoming ineffective at an alarming rate due to our misuse in healthcare, animals, and crops. Antibiotic resistance is responsible for 700,000 deaths each year, which is expected to continue rising – overtaking cancer by 2050. To slow this trend, we must start to use these drug...

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Pharma Companies PHARMA COMPANIES' EFFORTS TO ADDRESS DRUG-RESISTANT INFECTIONS

blog article

Jan 23, 2018

An independent analysis of pharmaceutical industry efforts to tackle drug resistance finds that, as well as developing new drugs, companies are also dismantling the incentives that encourage sales staff to oversell antibiotics, setting limits on the concentration of antibiotics in factory wastewater...

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Drug Synthesis In Printed Reactors DRUG SYNTHESIS IN PRINTED REACTORS

blog article

Jan 23, 2018

I’m still trying to get my bearings with this new paper from the Cronin group at Glasgow. What it proposes is a new style of API (active pharmaceutical ingredient) production. Instead of being done in bench- or process-scale lab glassware or in production-plant reactors, these syntheses take p...

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Artificial Intelligence in Pharmacy: Are You Ready? ARTIFICIAL INTELLIGENCE IN PHARMACY: ARE YOU READY?

blog article

Jan 22, 2018

Pharmacy as a profession and business continues to face challenges, and how it contributes value to the overall healthcare industry will determine its ongoing success. A key component of that may turn out to be effective use of technology, specifically artificial intelligence.

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Successful Trial in Antibody Treatment of HIV SUCCESSFUL TRIAL IN ANTIBODY TREATMENT OF HIV

blog article

Jan 19, 2018

A research team led by investigators of the Rockefeller University in New York and Prof Florian Klein, University Hospital Cologne and German Center for Infection Research (DZIF), has tested a new HIV neutralising antibody, called 10-1074, in humans. The results of the trial have just been published...

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Hospitals Making Drugs? HOSPITALS MAKING DRUGS?

blog article

Jan 19, 2018

This story from the New York Times got a lot of attention yesterday, and understandably so. It’s fundamentally about the shortage of some generic drugs, a problem that’s been with us for some years now in one form or another. My own belief is that much of this is a regulatory problem, an...

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Drug Development Insights from the 36th Annual J.P. Morgan Healthcare Conference DRUG DEVELOPMENT INSIGHTS FROM THE 36TH ANNUAL J.P. MORGAN HEALTHCARE CONFERENCE

blog article

Jan 19, 2018

The 2018 J.P. Morgan Healthcare Conference, held in San Francisco from January 8-11, came and went in a whirlwind. In just a few days, there were hundreds of speeches, presentations, panels and a tremendous amount of networking. The conference was devoted to the business of healthcare, with announce...

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Translational Medicine, Data Access and Pharmaceutical Innovation TRANSLATIONAL MEDICINE, DATA ACCESS AND PHARMACEUTICAL INNOVATION

blog article

Jan 17, 2018

Some of the early seeds of translational medicine were planted in 1992 when the U.S. National Cancer Institute introduced a program designed to improve and accelerate the knowledge exchange between basic and clinical science. Originally meant to address the slow growth of progress in cancer research...

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A Cure for Cancer? How CAR-T Therapy is Revolutionizing Oncology A CURE FOR CANCER? HOW CAR-T THERAPY IS REVOLUTIONIZING ONCOLOGY

blog article

Jan 16, 2018

CAR-T therapy has been hailed as a cure for cancer, but what really is this “miraculous technology” and what can we actually expect from it? The field of immuno-oncology is booming with billions of euros in investment. The ability to rewire our own immune system to fight cancer has certa...

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Regulators Adjust to Better Meet Pharma Market Needs REGULATORS ADJUST TO BETTER MEET PHARMA MARKET NEEDS

blog article

Jan 16, 2018

Christine M. V. Moore, Ph.D., Global Head and Executive Director, Merck & Co-led “Changes in the Regulatory Landscape,” an education session held 31 October during the 2017 ISPE Annual Meeting & Expo. The first speaker, Ellen F. Morrison, Assistant Commissioner of Medical Product...

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How FarmaTrust Plans to Revolutionize the Pharmaceutical Sector Using Blockchain HOW FARMATRUST PLANS TO REVOLUTIONIZE THE PHARMACEUTICAL SECTOR USING BLOCKCHAIN

blog article

Jan 15, 2018

Clever applications of blockchain technologies have the potential to fundamentally change lives. For instance, FarmaTrust, a highly anticipated and fast-growing startup, has developed an intelligent platform that, across a wide variety of features, optimizes the pharmaceutical industry by eliminatin...

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Drug Pricing Dominates Senate Hearing on HHS Nominee Azar DRUG PRICING DOMINATES SENATE HEARING ON HHS NOMINEE AZAR

blog article

Jan 10, 2018

If confirmed as the next secretary of the Department of Health and Human Services (HHS), Alex Azar says that a top priority is to make drugs more affordable. He agreed with members of the Senate Finance Committee at his confirmation hearing January 9 that “drug prices are too high,” but ...

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Rational drug design: How far have we come? RATIONAL DRUG DESIGN: HOW FAR HAVE WE COME?

blog article

Jan 08, 2018

From the early use of Hansch parameters and Topliss Trees to today’s computational structure–activity techniques, medicinal chemists have long sought to rationalise drug design to find the quickest and most resource-efficient route to market. But while modern strategies are more reliant ...

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Why you should work for a pharma start-up WHY YOU SHOULD WORK FOR A PHARMA START-UP

blog article

Jan 04, 2018

If we look at Aerie Pharmaceuticals and their new products Rhopressa and Roclatan, these are designed to reduce elevated intraocular pressure (IOP), the cause of vision loss in open-angle glaucoma. This is the largest prescription market in ophthalmology and it’s amazing to see such a breakthr...

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Pharma startup combines AI with cell images to target disease PHARMA STARTUP COMBINES AI WITH CELL IMAGES TO TARGET DISEASE

blog article

Jan 04, 2018

For centuries, modern medicine has grappled with the problem of finding the right drug treatment for the correct disease. While incremental progress is made every year, the lag time and expense of bringing a drug successfully to market have frustrated doctors, scientists, and patients. In search of ...

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Cancer Drug Raises Risk of Cardiovascular Toxicity CANCER DRUG RAISES RISK OF CARDIOVASCULAR TOXICITY

blog article

Jan 01, 2018

A drug approved by the FDA in 2012 to treat a type of cancer called multiple myeloma has dangerous side effects that involve the heart. The drug is called carfilzomib, and it is a proteasome inhibitor now linked to an increased risk of dangerous heart events. High blood pressure, heart failure, hear...

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NCI Director: AI Improves Cancer Research and Care NCI DIRECTOR: AI IMPROVES CANCER RESEARCH AND CARE

blog article

Jan 01, 2018

National Cancer Institute (NCI) Director Dr. Norman “Ned” Sharpless thinks artificial intelligence (AI), machine learning and big data can aid cancer researchers and caregivers. In fact, big data, along with basic research and the process of translating findings directly into treatments ...

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Schizophrenia and Drug Delivery Biotechs Sign a Major Pharma Partner SCHIZOPHRENIA AND DRUG DELIVERY BIOTECHS SIGN A MAJOR PHARMA PARTNER

blog article

Dec 19, 2017

Santa Claus is not the only busy one in the weeks leading up to Christmas this year, with Boehringer Ingelheim signing collaborations with Autifony and Evox Therapeutics. In the last couple of days, Boehringer Ingelheim has agreed to collaborate with two exciting British biotechs. On Monday, a deal ...

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Prescription pharmaceutical misuse on the rise PRESCRIPTION PHARMACEUTICAL MISUSE ON THE RISE

blog article

Dec 19, 2017

A new report from the Australian Institute of Health and Welfare, Non-medical use of pharmaceuticals: trends, harms, and treatment: 2006-07 to 2015-6, shows that the number of Australians misusing pharmaceutical drugs is rising. The report looks at two main types of pharmaceuticals: opioid analgesic...

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Pharmaceutical Company Pleads Guilty to Misbranding Oncology Drugs PHARMACEUTICAL COMPANY PLEADS GUILTY TO MISBRANDING ONCOLOGY DRUGS

blog article

Dec 19, 2017

Executives of AmerisourceBergen Specialty Group (ABSG), a wholly-owned subsidiary of AmerisourceBergen Corporation (ABC), pled guilty in September 2017 to illegally distributing misbranded drugs. The criminal charges stemmed from ABSG’s behavior between 2001 and 2014. Two of its subsidiaries, ...

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PRESCRIPTION DRUG TRENDS PRESCRIPTION DRUG TRENDS

blog article

Dec 12, 2017

A gene therapy treatment recently approved by the Food and Drug Administration for use against leukemia is priced at $475,000 for a one-time treatment.1 While it’s exciting that new treatments, including prescription drugs, appear to be getting closer to curing society’s most lethal dise...

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Critical Care: New Guidance for Medication Safety in the ICU CRITICAL CARE: NEW GUIDANCE FOR MEDICATION SAFETY IN THE ICU

blog article

Dec 11, 2017

The Society of Critical Care Medicine (SCCM) is committed to “Right Care, Right Now.”As part of this commitment, SCCM identifies patient care needs that require evidence-based best practice guidelines and works with experts to advance practices. Earlier this year, we published” Cli...

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Social Media Influencers in Healthcare and Pharma: What’s Their Role? SOCIAL MEDIA INFLUENCERS IN HEALTHCARE AND PHARMA: WHAT’S THEIR ROLE?

blog article

Dec 04, 2017

Looking to social media influencers for advice makes sense when you’re shopping for fashionable jeans, your next great vacation, or even inspiration for your fitness regime. Most retail brands agree. According to the research firm L2 Gartner, 70% of retail brands are working with influencers t...

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Formulation development of solid pharmaceuticals FORMULATION DEVELOPMENT OF SOLID PHARMACEUTICALS

blog article

Nov 30, 2017

For many decades, Bosch Pharma Service’s customers have benefited from our know-how in the production of solid pharmaceuticals – not only for the design and construction of machines and facilities and the production of solid pharmaceuticals but also for the products manufactured using th...

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Will Pharma Reach a Negative Return on its R&D Investments? WILL PHARMA REACH A NEGATIVE RETURN ON ITS R&D INVESTMENTS?

blog article

Nov 30, 2017

Pharma depends on innovation, which is why it turns to biotech as the powerhouse of novel technologies. About 65% of recently drugs come from small life sciences companies according to a report from HBM Partners.

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Galapagos Cystic Fibrosis Drug Enters Phase I, Triggering €8.5M Payout GALAPAGOS CYSTIC FIBROSIS DRUG ENTERS PHASE I, TRIGGERING €8.5M PAYOUT

blog article

Nov 22, 2017

Galapagos is a clinical-stage biotech developing small molecule medicines for a range of indications. It partnered up with the global pharma company, AbbVie, back in 2013, to develop a number of cystic fibrosis (CF) candidates for a combination therapy.

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How Medical Scribes Are Helping To Improve Patient Care HOW MEDICAL SCRIBES ARE HELPING TO IMPROVE PATIENT CARE

blog article

Nov 20, 2017

Medical scribes are one of the lesser known roles in the healthcare industry. They are an essential component, however, and their arrival has brought with it numerous benefits to institutions and to patients. Medical scribes are an increasingly common sight in doctors’ offices up and down the ...

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As Drug Development Costs Skyrocket, AI Offers Some Hope AS DRUG DEVELOPMENT COSTS SKYROCKET, AI OFFERS SOME HOPE

blog article

Nov 20, 2017

Last year, researchers from the Tufts Center for the Study of Drug Development published a paper in the Journal of Health Economics that provided an assessment of the current cost for pharmaceutical companies to discover and develop new drugs and biologics.

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A Practical Approach to the Challenges of Pediatric Drug Development A PRACTICAL APPROACH TO THE CHALLENGES OF PEDIATRIC DRUG DEVELOPMENT

blog article

Nov 17, 2017

Drug developers can’t take an adult clinical trial protocol and simply retool it for pediatrics. Yet, in my work at a pediatric clinical research organization (CRO), I frequently see sponsors attempt to do just that. Successfully implementing a pediatric drug development plan poses challenges ...

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Myelo Therapeutics Takes on Unmet Needs in Cancer MYELO THERAPEUTICS TAKES ON UNMET NEEDS IN CANCER

blog article

Nov 17, 2017

Many pharmaceutical and biotechnology start-ups have been founded for the purpose of taking on unmet needs. It has often been difficult for the larger, more established pharma companies to focus on these narrower problems, so the leaner.

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How in vitro assays and drug metabolism are being used to de-risk drug development HOW IN VITRO ASSAYS AND DRUG METABOLISM ARE BEING USED TO DE-RISK DRUG DEVELOPMENT

blog article

Nov 16, 2017

If all molecules in discovery and development were added together over recent years and compared to the number of successful drug approvals each year, the ratio is (approximately) 10,000:1. In other words, for every 10,000 molecules entering drug discovery, 9,999 will fail during some stage of the d...

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The Convergence of Digital Health, Devices and Pharma THE CONVERGENCE OF DIGITAL HEALTH, DEVICES AND PHARMA

blog article

Nov 15, 2017

There has been a huge push in policy circles to speed innovation in medicine which is manifest in several initiatives, including most notably the 21st Century Cures Act implementation. But it would be a mistake to assess the quickening pace of innovation solely through the lens of policy.

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City sues drug giants CITY SUES DRUG GIANTS

blog article

Nov 14, 2017

City Hall filed a lawsuit on Nov. 7 against Purdue Pharma and other pharmaceutical manufacturers and distributors, alleging that they are contributing to the opioid crisis in New Haven.

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Encourage Your Patients to Be Active Participants ENCOURAGE YOUR PATIENTS TO BE ACTIVE PARTICIPANTS

blog article

Nov 14, 2017

Patient engagement has all the intentions to improve the ability of every patient to create meaningful and solid relationships with their healthcare providers. When patients can have meaningful relationships with their healthcare providers, this will create the way for them to participate actively w...

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Pharma in the Digital Age PHARMA IN THE DIGITAL AGE

blog article

Nov 14, 2017

We are living in a digital age, and this results in more patients being less depending on their health care providers for advice and information. More patients are now able to take more control of their lives and their health.

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Pharmaceutical Industry Profits And Research And Development PHARMACEUTICAL INDUSTRY PROFITS AND RESEARCH AND DEVELOPMENT

blog article

Nov 13, 2017

When the challenge of affording prescription drugs is raised, pharmaceutical manufacturers often argue that steps to reduce prices will lead to less innovation in the future. This response presumably applies to policies that use the market, such as shortening periods of exclusivity and making approv...

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Governments Mount Opioid Lawsuit Wave at Purdue Pharma GOVERNMENTS MOUNT OPIOID LAWSUIT WAVE AT PURDUE PHARMA

blog article

Nov 10, 2017

Governments are swamping Purdue Pharma, makers of OxyContin, with opioid lawsuits alleging the company is responsible for the costs of opioid overdose.The continuing wave of opioid lawsuits coming at the makers of OxyContin, Purdue Pharma, based in Stamford, Connecticut, is growing. Recently, 28 Wis...

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Drug Companies Collaborate to Take on the Opioid Crisis DRUG COMPANIES COLLABORATE TO TAKE ON THE OPIOID CRISIS

blog article

Nov 08, 2017

The opioid crisis in the US is now responsible for taking more American lives each year than car crashes. The pharmaceutical industry has come under fire for having a role in the epidemic, with some companies being accused of deliberately downplaying the addictive dangers of opioids.

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Drug Companies Collaborate to Take on the Opioid Crisis DRUG COMPANIES COLLABORATE TO TAKE ON THE OPIOID CRISIS

blog article

Nov 08, 2017

The opioid crisis in the US is now responsible for taking more American lives each year than car crashes.The pharmaceutical industry has come under fire for having a role in the epidemic, with some companies being accused of deliberately downplaying the addictive dangers of opioids.

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Egyptian-American fund announces new pharmaceutical investment EGYPTIAN-AMERICAN FUND ANNOUNCES NEW PHARMACEUTICAL INVESTMENT

blog article

Nov 07, 2017

The Egyptian-American Enterprise Fund (EAEF) signed an agreement to acquire a minority stake in Orchidia Pharmaceutical Industries, the company announced in a statement earlier this week.

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Pharma’s digital patient engagement innovators identified PHARMA’S DIGITAL PATIENT ENGAGEMENT INNOVATORS IDENTIFIED

blog article

Nov 06, 2017

Pharmaceutical companies are making more of an effort to engage with European patients through digital challenges, but their success in doing so varies as a small handful of innovators starts to emerge. Decision Resources Group (DRG) identified Novartis, Pfizer and Sanofi as best-in-class when it ca...

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8 Things That Could Go Wrong With Your Pharma Marketing Campaign 8 THINGS THAT COULD GO WRONG WITH YOUR PHARMA MARKETING CAMPAIGN

blog article

Nov 06, 2017

Pharma marketing can sometimes feel like a thankless job  the web of overlapping indications, “second plus”-line treatments, FDA regulations and privacy landmines sapping the joy out of even seasoned industry veterans.

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The Fine Line of Pharma & Patient Group Collaboration THE FINE LINE OF PHARMA & PATIENT GROUP COLLABORATION

blog article

Nov 06, 2017

A new attempt by European drug firms and patient organizations to chart a course between cooperation and cooption has highlighted the scale of the challenges that healthcare stakeholders face when they reach out to one another.

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Europe Bio Pharmaceuticals Market Distribution and Key Players Analysis to 2021 EUROPE BIO PHARMACEUTICALS MARKET DISTRIBUTION AND KEY PLAYERS ANALYSIS TO 2021

blog article

Nov 06, 2017

According to the report Europe Bio Pharmaceuticals Market, published by Market Data Forecast, the Europe market is projected to reach USD 56.83 billion by 2021, at a CAGR of 8.89% from 2016 to 2021. Primarily biopharmaceuticals products are obtained from life forms or genetically modified plants and...

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The Drug Project Landscape THE DRUG PROJECT LANDSCAPE

blog article

Nov 03, 2017

Here’s a new paper in Nature Reviews Drug Discovery that’s going to the trouble of matching specific disease indications with specific mechanisms in drug projects over the last 20 years (both the successful ones and the unsuccessful ones).

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Non-core divestments in pharma could herald an increase in IP-rich deal making NON-CORE DIVESTMENTS IN PHARMA COULD HERALD AN INCREASE IN IP-RICH DEAL MAKING

blog article

Nov 02, 2017

Merck Group, Pfizer and Eli Lilly have, in quick succession, announced that they are considering moves to sell large, non-core parts of their businesses. Intellectual property, and its valuation, would inevitably play a large part in such transactions. But perhaps more significantly, the pressures f...

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Complex Generic Drug Products: A Changing Regulatory Landscape COMPLEX GENERIC DRUG PRODUCTS: A CHANGING REGULATORY LANDSCAPE

blog article

Nov 01, 2017

Earlier this year, the U.S. Food and Drug Administration (FDA) announced its Drug Competition Action Plan, which aims to bring more competition to the drug market and improve consumer access to drugs. As part of this effort, the Agency is focusing on ways to help bring complex generic drugs to marke...

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Pharma on Mars: Getting Drugs Ready for Deep Space Travel PHARMA ON MARS: GETTING DRUGS READY FOR DEEP SPACE TRAVEL

blog article

Nov 01, 2017

When we think of the challenges of space travel, we tend to focus on the technological aspects involving the difficulty of launch and landing, the structural integrity of the spacecraft and the basic safety of the astronauts.

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FDA Explores Flexible Drug Marketing Policies FDA EXPLORES FLEXIBLE DRUG MARKETING POLICIES

blog article

Nov 01, 2017

FDA regulation of prescription drug and medical product promotion has come under fire in recent years, as federal courts have supported industry challenges to rules limiting communications of unapproved drug uses.

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Pharmaceutical Filtration Devices Market: Comprehensive Industry Analysis & Global Foresight to 2022 PHARMACEUTICAL FILTRATION DEVICES MARKET: COMPREHENSIVE INDUSTRY ANALYSIS & GLOBAL FORESIGHT TO 2022

blog article

Nov 01, 2017

Globally, Pharmaceutical filtration Devices Market is growing rapidly and it is anticipated to show an exponential growth reaching approximately $23 Billion in 2022. Filtration in pharmaceutical has been used to purify or separate the component and also to maintain the sterile conditions during the ...

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Did Amazon Just Create a Solution to Pharma’s Last Mile Problem? DID AMAZON JUST CREATE A SOLUTION TO PHARMA’S LAST MILE PROBLEM?

blog article

Oct 31, 2017

Amazon just announced a new program that would allow delivery people into a person’s house. While this may help solve the problem of items being stolen off people’s porches and could make delivery of items that require signatures such as iPhones easier, it may also be another piece to Am...

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Trump TRUMP'S STUNNING NEW IDEA TO STOP THE OPIOID CRISIS: JUST SAY NO

blog article

Oct 26, 2017

Donald Trump appealed to his late brother’s struggle with addiction while declaring the opioid crisis a national public health emergency Thursday afternoon, an issue he plans to tackle in part by employing “really tough, really big advertising,” telling kids in a very serious voice...

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Biggest Blunders Pharma Marketers Make (And How To Correct Them) BIGGEST BLUNDERS PHARMA MARKETERS MAKE (AND HOW TO CORRECT THEM)

blog article

Oct 25, 2017

According to India Brand Equity Foundation, close to 80% of all medicines in India are prescription-based. This establishes doctors as the number one customer group of pharma marketers. Effective physician engagement, therefore, becomes the holy grail of pharma marketing success. However, the market...

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Design, formulation and manufacture of film-coated drug products DESIGN, FORMULATION AND MANUFACTURE OF FILM-COATED DRUG PRODUCTS

blog article

Oct 25, 2017

Film coating is a common step in tablet manufacture that can be used to improve product appearance, organoleptic properties, or to facilitate swallowing. Functional film coats can also be used as a part of the product’s stabilisation strategy and to modify or delay drug release.

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Harnessing Patient Communities for Pharma Marketing HARNESSING PATIENT COMMUNITIES FOR PHARMA MARKETING

blog article

Oct 23, 2017

What do people do when they are sick? Often, even before they call a doctor, they go online. And when they’re facing a health crisis or ongoing illness, more people than ever are turning to social media and online communities before, during, and after diagnosis.

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Building a Patient-Centered Pharmacy Immunization Service BUILDING A PATIENT-CENTERED PHARMACY IMMUNIZATION SERVICE

blog article

Oct 23, 2017

Critically important to the success of population health are vaccines that immunize children and adults against diseases like the flu, hepatitis B, measles, mumps, pneumonia and tetanus. With this growing need for effective immunization programs to manage population health, the American Pharmacists ...

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The European Regulatory Landscape for Pediatric Drug Development THE EUROPEAN REGULATORY LANDSCAPE FOR PEDIATRIC DRUG DEVELOPMENT

blog article

Oct 20, 2017

In my 35 years of working to develop safer, more effective medications for children, I’ve often been asked about how to navigate the regulatory landscape in the US and Europe. In a previous blog post, I discussed the latest FDA trends regarding pediatric drug development. In this blog, I&rsquo...

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Stability testing requirements for Pharmaceuticals and Medical Devices STABILITY TESTING REQUIREMENTS FOR PHARMACEUTICALS AND MEDICAL DEVICES

blog article

Oct 19, 2017

Accelerated stability tests provide a means of comparing alternative formula-dons, packaging materials, and/or manufacturing processes in short-term experiments. As soon as the final formulation and manufacturing process have been established, the manufacturer carries out a series of accelerated sta...

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FDA approves new robotic surgery device FDA APPROVES NEW ROBOTIC SURGERY DEVICE

blog article

Oct 17, 2017

US regulators have approved a new robotic surgery device for use in colorectal and gynecological operations. TransEnterix Surgical’s computer-assisted surgical S enhance System allows surgeons to sit at a console unit or cockpit that provides a 3-D high-definition view of the surgical field.

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New Rwanda Pharmaceutical Lab  To Test 100 Drug Types NEW RWANDA PHARMACEUTICAL LAB TO TEST 100 DRUG TYPES

blog article

Oct 17, 2017

Rwanda is upgrading its pharmaceutical laboratory to give it a capacity to test more strong drugs. By December this year, the newly introduced ‘Medical and pharmaceutical laboratory’ will have the capacity to test 100 types of medicine from 35 types since July when the laboratory started...

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A paradigm change in biologics microbiological contaminant control A PARADIGM CHANGE IN BIOLOGICS MICROBIOLOGICAL CONTAMINANT CONTROL

blog article

Oct 17, 2017

Even with the advent of biologics, the historical paradigm of microbiological control has largely continued on this path. The testing of artefacts that more specifically activate the adaptive immune system without setting off proinflammatory responses has taken place only recently.

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Pharma and medtech industries prepare for hard Brexit PHARMA AND MEDTECH INDUSTRIES PREPARE FOR HARD BREXIT

blog article

Oct 16, 2017

Drugmakers and medical devices companies are drawing up plans to protect supply chains in case Britain crashes out of the European Union without a trade deal, and some small service businesses are already relocating to stay inside the bloc.

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What does your pharma brand mean to patients? WHAT DOES YOUR PHARMA BRAND MEAN TO PATIENTS?

blog article

Oct 16, 2017

During the course of our research last summer, we had the opportunity to talk with patients and caregivers about the branding aspect of their prescription drugs. While branding is considered an important part of the marketing mix when it comes to launching a product, most patients don’t feel an affi...

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Can Streamlined R&D Reduce Drug Prices? CAN STREAMLINED R&D REDUCE DRUG PRICES?

blog article

Oct 11, 2017

The recent FDA approval of the first chimeric antigen receptor T cell (CAR-T) therapy to treat young patients with a serious form of leukemia reignited charges that high drug prices limit patient access to life-saving medicines.

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Manufacturing Generic Versions of Controlled Substances MANUFACTURING GENERIC VERSIONS OF CONTROLLED SUBSTANCES

blog article

Oct 09, 2017

Last Fall, we were pleased to announce that PCI Synthesis received DEA registration for controlled substance development and manufacturing, and we invested in new systems, processes, and training in order to manufacture controlled substances in our Newburyport facility.

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Community Oncology Practices as Clinical Trial Partners COMMUNITY ONCOLOGY PRACTICES AS CLINICAL TRIAL PARTNERS

blog article

Oct 09, 2017

Pharmaceutical manufacturers developing new cancer drugs and community oncology practices seeking new therapies for patients are ideal clinical trial partners. In my previous blog post, I described how community oncology practices can access clinical trials and optimize their participation to drive ...

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DSCSA: 2017 Deadline for Prescription Drug Manufacturers Fast Approaching DSCSA: 2017 DEADLINE FOR PRESCRIPTION DRUG MANUFACTURERS FAST APPROACHING

blog article

Oct 05, 2017

The Drug Supply Chain Security Act (DSCSA) is approaching full implementation, and companies at all levels of the pharmaceutical supply chain have to take note. Regulators put this system in place to ensure the traceability of prescription drugs all the way from their manufacture to end use.

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Members of Congress Side-Eye Pharma Company for Patent Shenanigans MEMBERS OF CONGRESS SIDE-EYE PHARMA COMPANY FOR PATENT SHENANIGANS

blog article

Oct 05, 2017

Congress is taking drug company Allergan to task for a bizarre legal scheme that involves using a Native American tribe as a shield against patent challenges. On Sept. 8, the pharmaceutical maker announced that it would be transferring disputed patents for Restasis, a dry-eye drug, to the Saint Regi...

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Epigenetic drugs show promise as antivirals EPIGENETIC DRUGS SHOW PROMISE AS ANTIVIRALS

blog article

Oct 05, 2017

Some epigenetic pharmaceuticals have the potential to be used as broad-spectrum antivirals, according to a new study. The study demonstrated that histone methyltransferases EZH2/1 inhibitors, which are being used in cancer clinical trials, have activity against a variety of viruses, including herpes...

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Shining the light on drug-drug interactions (DDI) SHINING THE LIGHT ON DRUG-DRUG INTERACTIONS (DDI)

blog article

Oct 04, 2017

Advancements in vitro technologies and analytical instrumentation over the past decade allow scientists to apply a variety of in vitro based assays designed to rapidly assess risk-liability, such as drug-drug interactions (DDI), one of the factors contributing to both current high attrition rates an...

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California Takes On Drug Pricing: Real Progress Or Illusion? CALIFORNIA TAKES ON DRUG PRICING: REAL PROGRESS OR ILLUSION?

blog article

Oct 02, 2017

Californians and others around the country following the California legislature’s multiyear debate on prescription drug pricing may have stood up and taken notice on September 13 when the state Senate followed the Assembly in passing SB-17 to facilitate greater transparency in brand-name and generic...

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The Importance of Selecting the Most Promising Drug Target THE IMPORTANCE OF SELECTING THE MOST PROMISING DRUG TARGET

blog article

Sep 27, 2017

The growing economic pressure due to late-stage drug approval failures has been forcing drug discovery and development scientists to adapt their strategies in order to increase their chances of success. While it’s important to optimize drug candidates with respect to pharmacokinetics, efficacy and t...

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Cipla Europe: one more Pharma Laboratory that is added to ebuyfarma CIPLA EUROPE: ONE MORE PHARMA LABORATORY THAT IS ADDED TO EBUYFARMA

blog article

Sep 25, 2017

Cipla Europe: one more Pharma Laboratory that is added to our platform B2B Cipla is a leader pharmaceutical company with global presence, dedicated to manufacture medicines of high quality, including brands and generics, present in the India, south Africa, states united and emerging countries. It is...

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Is the Pharma Industry Missing the Big Picture? IS THE PHARMA INDUSTRY MISSING THE BIG PICTURE?

blog article

Sep 22, 2017

There is a disconnect between how drugs are developed and how they are used. In the traditional method of target-oriented development, each new candidate drug is scrutinized in a handful of interactions with desirable and undesirable targets.

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More than 85 medicines in development for Alzheimer’s disease MORE THAN 85 MEDICINES IN DEVELOPMENT FOR ALZHEIMER’S DISEASE

blog article

Sep 21, 2017

When Brian Kursonis started “blanking out” for moments at a time, a scan revealed plaques of a protein called amyloid in the brain, one sign of Alzheimer’s disease. A test of his spinal fluid found high levels of amyloid and tau, another protein linked to the condition.

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What is immuno-oncology? Uncovering the future of cancer therapy WHAT IS IMMUNO-ONCOLOGY? UNCOVERING THE FUTURE OF CANCER THERAPY

blog article

Sep 20, 2017

Hailed as one of the most exciting and unique cancer treatments of today, here’s everything you need to know about this medical marvel. The definition of immunotherapy is the use of the body’s natural defences (immune system) to fight disease. What is immuno-oncology? Immuno-oncology is a type of im...

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Thousands of pharmacies at a click: the revolution in pharmaceutical distribution comes hand in hand with the launch "ebuyfarma" THOUSANDS OF PHARMACIES AT A CLICK: THE REVOLUTION IN PHARMACEUTICAL DISTRIBUTION COMES HAND IN HAND WITH THE LAUNCH "EBUYFARMA"

blog article

Sep 19, 2017

Well, today's pharmacies, as emerging companies, have a strong working relationship with technology. It is a new business model, with innovative ideas, that excel in the market to be supported by the applied sciences. Precisely, a startup is a human organization, with a strong technological componen...

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ATMPs – patient-specific drugs on their way to market ATMPS – PATIENT-SPECIFIC DRUGS ON THEIR WAY TO MARKET

blog article

Sep 18, 2017

At the end of the last millennium, a new form of medicine was introduced that today, some 30 years later, likely appears to be fulfilling the promises made at that time. ATMP, “Advanced Therapy Medicinal Products“, delineate novel forms of therapy.

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Adjudicating Cardiovascular Endpoints in Diabetic Kidney Disease Studies ADJUDICATING CARDIOVASCULAR ENDPOINTS IN DIABETIC KIDNEY DISEASE STUDIES

blog article

Sep 14, 2017

Diabetic kidney disease (DKD) patients have an increased cardiovascular (CV) risk in addition to their increased risk of progression to end-stage renal disease. Recognizing that the FDA and other regulatory agencies have great interest in both the CV and renal safety and efficacy of compounds under ...

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The Challenges of Signal Detection in Spontaneous Reporting THE CHALLENGES OF SIGNAL DETECTION IN SPONTANEOUS REPORTING

blog article

Sep 13, 2017

Pharmacovigilance is essential to pharmaceutical businesses. It facilitates the correct use of a drug, safeguarding the drug as a meaningful treatment option when the benefits it offers outweigh known risks, or measures can be taken to mitigate those risks.

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Reflections on the preregistration assessment REFLECTIONS ON THE PREREGISTRATION ASSESSMENT

blog article

Sep 12, 2017

With the current preregistration trainees starting to settle into their new roles, I thought it would be timely to reflect on the preregistration assessment after completing it myself this year. This is the second year of the new assessment format where the questions are scenario based; this encoura...

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Pharma patent wars: Brilliant tactics; terrible optics PHARMA PATENT WARS: BRILLIANT TACTICS; TERRIBLE OPTICS

blog article

Sep 12, 2017

Whether or not you know it, or care to acknowledge it, a global war between the makers of branded drugs and generics has been going on for decades. In return for the expense of development, drug makers are granted patents that allow them exclusive rights to sell their products.

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What they are saying: Study on cancer R&D costs is not an accurate representation of marketplace WHAT THEY ARE SAYING: STUDY ON CANCER R&D COSTS IS NOT AN ACCURATE REPRESENTATION OF MARKETPLACE

blog article

Sep 12, 2017

A recent study published in JAMA Internal Medicine provides flawed and inaccurate estimates of the significant research and development (R&D) investments made by biopharmaceutical companies to develop new cancer treatments and cures for patients. The study focuses on a selective sample of companies ...

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What WHAT'S NEXT FOR INHALED MEDICATIONS AND INHALATION TECHNOLOGY?

blog article

Sep 11, 2017

Current estimates suggest that as many as 235 million people worldwide have asthma and over 200 million people have the chronic obstructive pulmonary disease (COPD). With rates set to increase, the need for efficacious medications for these incurable diseases is a major focus for research.

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The Vital Role of Patient Advocacy in Charting the Future of Medicine THE VITAL ROLE OF PATIENT ADVOCACY IN CHARTING THE FUTURE OF MEDICINE

blog article

Sep 09, 2017

For many of us, it is not difficult to remember a time where the role of patient advocacy in science and medicine was far different, and much more limited, than it is today. Patient advocacy organizations were, by and large, relied upon to elevate awareness of their target illnesses, raise money and...

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Resolution to Dissolution: Making Better Drugs RESOLUTION TO DISSOLUTION: MAKING BETTER DRUGS

blog article

Sep 08, 2017

There is a widening gap between the discovery of potential new drugs and their successful product development. Drugs are increasingly complex and diverge from Lipinski’s rule of 5, the industry standard for predicting a drug’s bioavailability and solubility. Contemporary literature reports that grea...

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What to Do When the Microorganisms Get to You WHAT TO DO WHEN THE MICROORGANISMS GET TO YOU

blog article

Sep 06, 2017

For the first time, ever an injectable clinical batch has been manufactured with the help of single-use technologies. A great way of fighting unwanted contamination in drug development! Have you ever opened a petri-dish and found an unknown growth on your medium? The same medium you had carefully pr...

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Expanding Treatment Options to Address Unmet Need in Blood Cance EXPANDING TREATMENT OPTIONS TO ADDRESS UNMET NEED IN BLOOD CANCE

blog article

Sep 05, 2017

Every three minutes, someone in the United States is diagnosed with a type of blood cancer. Blood cancers affect the production and function of blood cells and typically begins in bone marrow, where blood is produced. When blood cells become cancerous, uncontrolled growth of abnormal blood cells int...

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ICYMI: Drug Pricing Bill Is Bad for Business, Patients ICYMI: DRUG PRICING BILL IS BAD FOR BUSINESS, PATIENTS

blog article

Sep 05, 2017

Researchers and biotech leaders continue to discover new cures and treatments that are making a positive difference in the lives of patients. But unfortunately, there are some policymakers in Washington D.C. and various state capitals who continue to push misguided proposals that will undermine biom...

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Serialization, aggregation, coding formats – global challenges for the Pharma industry SERIALIZATION, AGGREGATION, CODING FORMATS – GLOBAL CHALLENGES FOR THE PHARMA INDUSTRY

blog article

Sep 01, 2017

According to the OECD, counterfeit medicines are responsible for more than 700,000 deaths annually. Up to 30% of all medicines are estimated to be fake in emerging and developing countries, says the World Health Organization (WHO). While fake drugs are potentially lethal, parallel markets and counte...

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Selecting Anti-Melanoma Drug Targets SELECTING ANTI-MELANOMA DRUG TARGETS

blog article

Aug 28, 2017

Every year, hundreds of thousands of people are diagnosed with melanoma, the deadliest form of skin cancer. Although rates of melanoma have continued to rise over the last three decades, the traditional treatment—chemotherapy—has had limited effectiveness in fighting this aggressive cancer. As a res...

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Pharmaceutical Data Integrity: Are Your Controls Tough Enough? PHARMACEUTICAL DATA INTEGRITY: ARE YOUR CONTROLS TOUGH ENOUGH?

blog article

Aug 25, 2017

As pharmaceutical supply chains have grown in complexity and international outsourcing becomes the new norm, the data used by drug developers and manufacturers to make decisions on production line design, quality control and batch release is coming under greater scrutiny from regulatory authorities....

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What is pharmacovigilance and why is it important? WHAT IS PHARMACOVIGILANCE AND WHY IS IT IMPORTANT?

blog article

Aug 23, 2017

Pharmacovigilance is concerned with only two outcomes: safety and efficacy. Does a drug work and is it safe? It touches on almost every aspect of the drug lifecycle - from preclinical development to post-market surveillance - making it one of the most fundamental functions within a life science comp...

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Insulin Pumps Pharmaceutical, Healthcare disease & Therapeutics Development & Drug Profile involved in the Pipeline Assessment 2017 INSULIN PUMPS PHARMACEUTICAL, HEALTHCARE DISEASE & THERAPEUTICS DEVELOPMENT & DRUG PROFILE INVOLVED IN THE PIPELINE ASSESSMENT 2017

blog article

Aug 22, 2017

The Medical Devices sector report, “Insulin Pumps – Medical Devices