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Lower dose of Pfizer-Lilly painkiller misses main goals in late stage study LOWER DOSE OF PFIZER-LILLY PAINKILLER MISSES MAIN GOALS IN LATE STAGE STUDY

blog article

Apr 19, 2019

A study, being carried out by the companies to test the effectiveness of lower doses of tanezumab for osteoarthritis, reported negative results. A lower dose of non-opioid painkiller developed by Pfizer and Eli Lilly and Company failed to meet main goals in a late-stage study in patients with modera...

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Early Physician Ally Will Serve as Witness Against Drug Manufacturers EARLY PHYSICIAN ALLY WILL SERVE AS WITNESS AGAINST DRUG MANUFACTURERS

blog article

Apr 19, 2019

Dr. Russell Portenoy, a professor at the Albert Einstein College of Medicine and an early physician ally of Purdue Pharma LP. whose views helped drive the push for addictive pain relievers for common aches and pains in the United States, has agreed to act as a witness and testify against the OxyCont...

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White House Continues to Tackle Opioid Abuse With $350 Million R&D Initiative WHITE HOUSE CONTINUES TO TACKLE OPIOID ABUSE WITH $350 MILLION R&D INITIATIVE

blog article

Apr 19, 2019

The goal of this investment is to reduce opioid-overdose deaths by as much as 40 percent in communities across four states that have been hit hard by the epidemic. According to the U.S. Department of Health and Human Services, 116 Americans die daily from opioid overdoses.

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The Fast-Approaching Changes Business Owners Will Need to Watch Out for Ahead THE FAST-APPROACHING CHANGES BUSINESS OWNERS WILL NEED TO WATCH OUT FOR AHEAD

blog article

Apr 19, 2019

When it comes to labor law, it is a changing landscape for area businesses, proven by Jackson Lewis’s recent year-ahead review. The 2019: Year Ahead for Employers, published recently by the nationwide law firm, sheds light on a range of pressing issues for companies both in and out of the 914....

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United Therapeutics Fires Back After Sandoz Files Anti-Competitive Lawsuit Over PAH Drug UNITED THERAPEUTICS FIRES BACK AFTER SANDOZ FILES ANTI-COMPETITIVE LAWSUIT OVER PAH DRUG

blog article

Apr 19, 2019

United Therapeutics is taking on accusations that it is unfairly blocking competitors from launching generic versions of the company’s top-selling pulmonary arterial hypertension (PAH) drug, Remodulin.

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5 Top Healthcare Stocks to Buy in 2019 5 TOP HEALTHCARE STOCKS TO BUY IN 2019

blog article

Apr 19, 2019

We're nearing the end of another decade. It had been a decade in which stocks have generally performed very well. And one sector has outperformed the S&P 500 index in total return every year but one this decade. Which sector is it? If you guessed healthcare, pat yourself on the back.

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Patients Rank Pharma Companies in New Perspective Survey PATIENTS RANK PHARMA COMPANIES IN NEW PERSPECTIVE SURVEY

blog article

Apr 19, 2019

It is probably fair to say that a significant number of people have a love-hate relationship with the pharma industry. People love the medications and innovations that treat a wide swath of diseases and illnesses, yet, when it comes to list prices, those tend to raise the hackles of people.

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Microbix Announces Management Changes MICROBIX ANNOUNCES MANAGEMENT CHANGES

blog article

Apr 18, 2019

An innovator of biological products and technologies, announces that it has appointed Dr. Kenneth (Ken) Hughes as its Chief Operating Officer ("COO") and that Mrs. Kathryn Froh, its Vice President, Diagnostics is retiring from her full-time role, but will be remaining an employee and will ...

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PathLAKE: Benefitting Pathologists With Exemplary Projects PATHLAKE: BENEFITTING PATHOLOGISTS WITH EXEMPLARY PROJECTS

blog article

Apr 17, 2019

David is Consultant Histopathologist and Clinical lead for Coventry and Warwickshire Pathology Services (CWPS), a network of labs hosted by University Hospitals of Coventry and Warwickshire NHS Trust. As head of the UHCW Digital Pathology Centre of Excellence, he is now heavily involved in the Patho...

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Takeda adds reinforcement to its investor charm offensive TAKEDA ADDS REINFORCEMENT TO ITS INVESTOR CHARM OFFENSIVE

blog article

Apr 16, 2019

Financing and creating enduring confidence around a deal like Takeda’s $62 million purchase of Shire. To continue reading The Pharma Letter please login,  subscribe or claim a 7 day free trial subscription and access exclusive features, interviews, round-ups and commentary from the sharpe...

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Pharmaceutical manufacturers resist calls for transparency on medicine prices PHARMACEUTICAL MANUFACTURERS RESIST CALLS FOR TRANSPARENCY ON MEDICINE PRICES

blog article

Apr 16, 2019

The International Federation of Pharmaceutical Manufacturers and Associations (IFPMA) says health activists’ call last week for greater transparency on medicine prices could backfire, and drive up drug costs in low and middle-income countries. Activists stepped up their campaign ahead of the F...

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Vetter’s Skokie Facility Expansion Nears Completion VETTER’S SKOKIE FACILITY EXPANSION NEARS COMPLETION

blog article

Apr 16, 2019

Vetter, a global operating Contract Development and Manufacturing Organization (CDMO) announced today that a significant level of expansion activities are nearing completion at its US clinical manufacturing facility located at the Illinois Science & Technology Park in suburban Chicago. The ongoi...

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Need more pharmacists in Uganda NEED MORE PHARMACISTS IN UGANDA

blog article

Apr 16, 2019

The world commemorated the World Health Workers Week from April 1-7. The week is meant to celebrate the amazing work done by health workers and to raise awareness on the challenges they face. “Most importantly, it is to provide an opportunity to fill in the gaps in the health work force by cal...

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Scientist.com Launches Trial Insights, A Transformative Clinical Trials Data Analytics Solution SCIENTIST.COM LAUNCHES TRIAL INSIGHTS, A TRANSFORMATIVE CLINICAL TRIALS DATA ANALYTICS SOLUTION

blog article

Apr 16, 2019

The online marketplace for outsourced research, announced today the launch of Trial Insights, a digital reporting solution that simplifies data produced through clinical trial, biomarker and medical diagnostic studies into an intuitive and user-friendly dashboard. The first of its kind, Trial Insigh...

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Side Effects: Nearly A Year In, Pennsylvania’s Medical Marijuana Law Still Has Issues To Work Out SIDE EFFECTS: NEARLY A YEAR IN, PENNSYLVANIA’S MEDICAL MARIJUANA LAW STILL HAS ISSUES TO WORK OUT

blog article

Apr 16, 2019

Tucked into Penn Avenue in the Strip District, across from Roxanne’s Dried Flowers, sits another kind of dried flower shop: the CY+ Dispensary. Owned by Cresco Labs, the medical cannabis retail store opened in June 2018 and several months later they established the Pennsylvania Medical Marijua...

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Rite Aid To Stop e-Cigarette Sales In Its Stores, Sell CBD Products In Two States RITE AID TO STOP E-CIGARETTE SALES IN ITS STORES, SELL CBD PRODUCTS IN TWO STATES

blog article

Apr 16, 2019

With a crackdown on the e-cigarettes, Rite Aid is now going to sell CBD products comprising of creams, lip balms and lotion in its 200 stores spread across states of Oregon and Washington this month. This step has been taken after the interests of the customers in the purchase of CBD products as say...

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Origin: The pharma supply chain of the future ORIGIN: THE PHARMA SUPPLY CHAIN OF THE FUTURE

blog article

Apr 15, 2019

In an industry that evolves every day, having first mover advantage is a must for any pharmaceutical manufacturer looking to compete. Knowledge, infrastructure and foresight are key to remain efficient and agile as the industry faces numerous forces which are reshaping and dictating the direction of...

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As superbugs threaten to create a global crisis, why are pharmaceutical companies shying away from antibiotics research. AS SUPERBUGS THREATEN TO CREATE A GLOBAL CRISIS, WHY ARE PHARMACEUTICAL COMPANIES SHYING AWAY FROM ANTIBIOTICS RESEARCH.

blog article

Apr 15, 2019

“China is a horror, India is a mega-horror,” says Alan Westwood, managing director of Matoke, a company hoping to develop a new form of antibiotic. “Russia is terrible. Don’t get sick in Greece either, the resistance rates are big, and in southern Europe generally.” Ant...

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Pharmaceutical supplier opts for hygienic flowmeter PHARMACEUTICAL SUPPLIER OPTS FOR HYGIENIC FLOWMETER

blog article

Apr 15, 2019

Specialist process machinery manufacturer, L.B. Bohle, has developed a cleaning system for the pharmaceutical industry using Bürkert's innovative FloWave flowmeter for a compact, hygienic and very accurate process. Incorporating the latest in flow measurement technology has minimised equipm...

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The UK as a global leader in antimicrobial resistance THE UK AS A GLOBAL LEADER IN ANTIMICROBIAL RESISTANCE

blog article

Apr 15, 2019

The Government wants the UK to become a leader in the development of products which tackle the global challenge of antimicrobial resistance (AMR). Despite the renewal of the 5-year AMR Strategy, there is no time to wait before driving new antimicrobial innovations into the mainstream. There must be ...

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ABPI Code feedback ABPI CODE FEEDBACK

blog article

Apr 15, 2019

It has long been communicated to the UK pharmaceutical industry that the Prescription Medicines Code of Practice Authority (PMCPA) welcomes all input and feedback on the ABPI Code of Practice. But what does this actually mean, what does the PMCPA do with such feedback, and what motivates feedback or...

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Innovative Medicines Initiative launches Translational Safety Biomarker Pipeline Project INNOVATIVE MEDICINES INITIATIVE LAUNCHES TRANSLATIONAL SAFETY BIOMARKER PIPELINE PROJECT

blog article

Apr 15, 2019

The University of Zurich coordinates a worldwide research project that focuses on the development of new biomarkers. The biomarkers are expected to improve safety of new drugs and to contribute to better diagnosis and management of acute and chronic diseases. The project is funded by the Innovative ...

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Tackling the high price of medicine TACKLING THE HIGH PRICE OF MEDICINE

blog article

Apr 15, 2019

US citizens pay about six times what Europeans do for insulin, the cost of which has almost tripled over a decade in that country, according to the American Diabetes Association. Meanwhile, Humira, the most popular arthritis medicine in the US, costs patients in the region of $50,000 (R700,000) a ye...

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Five Industries Being Transformed By Artificial Intelligence FIVE INDUSTRIES BEING TRANSFORMED BY ARTIFICIAL INTELLIGENCE

blog article

Apr 15, 2019

Technology is a transformative force, and there is currently no technology more transformative than AI. Because AI encompasses so many different fields -- from robotics to deep learning to self-driving cars -- it can be hard to quantify the exact impact it has had on the economy and on individual in...

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Big pharma might cut R&D, delay new drugs if more generics with pharmacare BIG PHARMA MIGHT CUT R&D, DELAY NEW DRUGS IF MORE GENERICS WITH PHARMACARE

blog article

Apr 15, 2019

Brand-name drug companies could put off introducing new medicine in Canada and scale back research here if the country makes a major shift to cheaper generic alternatives under a national pharmacare plan, according to an internal federal analysis. The concerns were included last year in a briefing d...

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Does the Falsified Medicines Directive go far enough across the supply chain. DOES THE FALSIFIED MEDICINES DIRECTIVE GO FAR ENOUGH ACROSS THE SUPPLY CHAIN.

blog article

Apr 15, 2019

As one of the largest health threats to populations around the world, falsified medicine has become a central focus of governments, agencies and pharmaceutical companies over recent years. Now considered to be the world’s largest fraud market, thought to be worth over $200 billion per year acc...

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Labour’s Dan Carden: the world urgently needs a fair price for medicines LABOUR’S DAN CARDEN: THE WORLD URGENTLY NEEDS A FAIR PRICE FOR MEDICINES

blog article

Apr 12, 2019

Every year, 100 million people across the world are pushed into poverty because of out-of-pocket healthcare expenses. While gains have been made in reducing the price of treatment for diseases such as HIV, there is still a long way to go to ensure people can access the essential medicines they need....

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Big pharma: stop dodging taxes! BIG PHARMA: STOP DODGING TAXES!

blog article

Apr 12, 2019

A new report shows that the big pharma has enjoyed a whopping $7 billion tax cut in 2018 thanks to Trump’s new corporate-friendly tax rules. In just over a week’s time, Oxfam will be confronting Johnson & Johnson execs at the company’s big shareholder meeting -- and delivering ...

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Pharma VP on the importance of innovation and affordable access to life-changing treatments PHARMA VP ON THE IMPORTANCE OF INNOVATION AND AFFORDABLE ACCESS TO LIFE-CHANGING TREATMENTS

blog article

Apr 12, 2019

On April 14 and 15, health ministers will be discussing access to health care for all EU citizens during an informal Health Council meeting in Bucharest. In this context, Martin Price, vice president for health economics, market access and reimbursement EMEA at Janssen Pharmaceutical Companies of Jo...

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Who Profits From Drug Price Decreases? WHO PROFITS FROM DRUG PRICE DECREASES?

blog article

Apr 12, 2019

According to a new analysis released last month, Americans spent $3.65 trillion dollars on health care in 2018 – more than the entire gross domestic product of Canada. That’s over $11,000 per person, and it reflects a growing affordability crisis that threatens the health of millions of ...

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Arrowhead Presents Clinical Data at The International Liver Congress ARROWHEAD PRESENTS CLINICAL DATA AT THE INTERNATIONAL LIVER CONGRESS

blog article

Apr 12, 2019

PASADENA, Calif.--(BUSINESS WIRE)-- Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced the presentation of clinical data from an ongoing Phase 1/2 study (AROHBV1001) of JNJ-3989 (formerly ARO-HBV), a third-generation subcutaneously administered RNA interference (RNAi) therapeutic candida...

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Medical scopes still causing superbug infections, deaths MEDICAL SCOPES STILL CAUSING SUPERBUG INFECTIONS, DEATHS

blog article

Apr 12, 2019

(CNN) - Three people died and 45 people developed infections from contaminated endoscopes, the US Food and Drug Administration said Friday. The reports of contamination are with a side-viewing duodenoscope used for a medical procedure called endoscopic retrograde cholangiopancreatography or ERCP. &q...

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ASTRAZENECA & MSD INC WIN EU APPROVAL FOR BREAST-CANCER DRUG LYNPARZA ASTRAZENECA & MSD INC WIN EU APPROVAL FOR BREAST-CANCER DRUG LYNPARZA

blog article

Apr 12, 2019

AstraZeneca and U.S. partner MSD Inc. have made it to the headlines for winning European Commission’s approval for Lynparza (olaparib), their blockbuster candidate originated and developed in Cambridge for the treatment of breast Cancer. As per trusted sources, the candidate has been backed by...

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Correction: Importing Prescription Drugs story CORRECTION: IMPORTING PRESCRIPTION DRUGS STORY

blog article

Apr 12, 2019

TALLAHASSEE, Fla. (AP) — Floridians could eventually gain access to cheaper Canadian prescription drugs under legislation passed Thursday by the state House, a top priority of Republican Gov. Ron DeSantis. The GOP-led House voted 93-22 on Thursday for the measure, which if finalized creates a ...

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Picking up the pieces of Connecticut PICKING UP THE PIECES OF CONNECTICUT'S ECONOMY

blog article

Apr 12, 2019

Hop on a Metro-North out of New York City on the New Haven Line. Soon, you’ll hit the pristine picket fences and well-manicured mansions of Fairfield County — the wealthiest metropolitan area in the nation, where finance and industry titans rake in million-dollar incomes and send their c...

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Fidia Pharma USA Inc. Announces Expansion into the Dietary Supplement Market with Launch of CartiJoint. FIDIA PHARMA USA INC. ANNOUNCES EXPANSION INTO THE DIETARY SUPPLEMENT MARKET WITH LAUNCH OF CARTIJOINT.

blog article

Apr 12, 2019

A world leader in the research, development, and manufacturing of hyaluronic acid (HA)-based products, is introducing CartiJoint™ FORTE, its first product in the dietary supplement category in the USA. CartiJoint™ FORTE is a dietary supplement that supports joint health and mobility with...

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Improving Lung Cancer Survival and Alleviating Chemotherapy-induced Neutropenia IMPROVING LUNG CANCER SURVIVAL AND ALLEVIATING CHEMOTHERAPY-INDUCED NEUTROPENIA

blog article

Apr 11, 2019

Neutropenia is a common, often severe adverse effect experienced by cancer patients who are undergoing chemotherapy treatment. We recently spoke with Dr Lan Huang, CEO at BeyondSpring, a clinical-stage biopharmaceutical company to learn more about the company’s efforts to develop innovative im...

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Federal research is important, but companies turn it into actual treatments FEDERAL RESEARCH IS IMPORTANT, BUT COMPANIES TURN IT INTO ACTUAL TREATMENTS

blog article

Apr 11, 2019

The March 27 front-page article “Pharma giant profits from HIV drug” perpetuated a misleading narrative in the drug pricing debate. The federal government plays a vital role as our society seeks to conquer disease and alleviate human suffering. Its support of basic research expands our s...

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Janssen’s HIV Drug Symtuza Shows Long-Term Effect in Late Stage Trial JANSSEN’S HIV DRUG SYMTUZA SHOWS LONG-TERM EFFECT IN LATE STAGE TRIAL

blog article

Apr 11, 2019

Less than one year ago, Janssen’s Symtuza got the green light from U.S. regulators as a treatment for HIV-1. This morning, the company presented new data that the medication provided sustained treatment through 48 weeks. At the 13th Annual American Conference for the Treatment of HIV in Miami,...

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Immuron To Pursue Clinical Development Through FDA For IMM-124E As TD Drug IMMURON TO PURSUE CLINICAL DEVELOPMENT THROUGH FDA FOR IMM-124E AS TD DRUG

blog article

Apr 11, 2019

Immuron Limited (ASX: IMC)  is a biopharmaceutical sector company with operations in Australia. The group is also engaged in the commercialization and development of oral immunoglobulin therapeutics for the treatment of gut mediated diseases. The company today, on 11th April 2019, announced pla...

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Tetra Bio-Pharma and Ovensa Will Engage in a Collaboration to Tackle Brain Cancer TETRA BIO-PHARMA AND OVENSA WILL ENGAGE IN A COLLABORATION TO TACKLE BRAIN CANCER

blog article

Apr 11, 2019

OTTAWA, April 11, 2019 (GLOBE NEWSWIRE) — Tetra Bio-Pharma Inc. (“Tetra” or the “Company”) (TSX-V: TBP) (OTCQB: TBPMF), today announced that it has entered into a collaboration agreement with Ovensa Inc. (“Ovensa”) to evaluate TRIOZAN™, a proprietary n...

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Realising the promise of laboratory automation in biomedical research REALISING THE PROMISE OF LABORATORY AUTOMATION IN BIOMEDICAL RESEARCH

blog article

Apr 11, 2019

Automation offers a choice of powerful ways to design and execute high-quality laboratory research. The use of lab automation is now pervasive in biomedical labs, offering versatile platforms on which to perform an ever‑expanding array of tasks free of human errors, and a unique means to address the...

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Transforming drug discovery, development and delivery with flow chemistry TRANSFORMING DRUG DISCOVERY, DEVELOPMENT AND DELIVERY WITH FLOW CHEMISTRY

blog article

Apr 11, 2019

Flow chemistry is on the rise thanks to the commercial availability of benchtop continuous flow systems that has driven widespread adoption of the technique across a broad range of applications in both academia and industry. In particular, flow chemistry is delivering significant benefits in the are...

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Enesi Pharma and University of Oxford collaborate to target plague with a novel ImplaVax®-enabled adenovirus-based solid dose vaccine ENESI PHARMA AND UNIVERSITY OF OXFORD COLLABORATE TO TARGET PLAGUE WITH A NOVEL IMPLAVAX®-ENABLED ADENOVIRUS-BASED SOLID DOSE VACCINE

blog article

Apr 10, 2019

Enesi Pharma (“Enesi”), an innovative pharmaceutical company developing unique injectable solid dose drug-device vaccine products and scientists at the world-renowned Oxford Vaccine Group (“OVG”) at the University of Oxford, announce they have entered into a collaborative agr...

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New HIV vaccine could expose latent virus and kill it NEW HIV VACCINE COULD EXPOSE LATENT VIRUS AND KILL IT

blog article

Apr 09, 2019

Antiretroviral therapy may soon be obsolete, as scientists have successfully used immune cells to kick the dormant form of HIV out of its hiding place and destroy it. The findings may soon lead to an HIV vaccine. According to recent estimates, around 1.1 millionpeople in the United States have HIV. ...

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Cancer: CANCER: 'OFF-THE-SHELF' STEM CELL TREATMENT ENTERS CLINICAL TRIAL

blog article

Apr 09, 2019

In a first-of-its-kind trial in the United States, researchers are testing a stem cell-derived natural killer cell immunotherapy in people with incurable cancer. Cancer follows heart disease as the secondbiggest killer worldwide. In the United States, an estimated 606,880 people will die due to canc...

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4 pharma companies saved $7 billion from GOP tax law 4 PHARMA COMPANIES SAVED $7 BILLION FROM GOP TAX LAW

blog article

Apr 09, 2019

Four pharmaceutical companies — Johnson & Johnson, Pfizer, Merck and Abbott Laboratories — collectively kept $7 billion in tax savings in 2018 due to Republicans' 2017 corporate tax overhaul, according to a new Oxfam report. The bottom line: Oxfam's results mirror our reporti...

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Demand that pregnant mares stop being tortured to collect their urine for Pfizer DEMAND THAT PREGNANT MARES STOP BEING TORTURED TO COLLECT THEIR URINE FOR PFIZER

blog article

Apr 08, 2019

The hormone replacement drug Premarin comes from pregnant mares' urine — that's how the drug got its name. But in order for the giant pharmaceutical corporation Pfizer to create Premarin, first it needs to make sure it has access to lots of pregnant horses. These mares are repeatedly i...

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Veratrak wants to digitise the pharmaceutical supply chain VERATRAK WANTS TO DIGITISE THE PHARMACEUTICAL SUPPLY CHAIN

blog article

Apr 08, 2019

Veratrak, a London-based startup that aims to digitise the pharmaceutical supply chain, has picked up £1 million in seed funding. Leading the round is Force Over Mass, with participation from Seedcamp, Ascension Ventures, Blockchain Valley Ventures and TrueSight Ventures. A number of individua...

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The absurdly high cost of insulin, explained THE ABSURDLY HIGH COST OF INSULIN, EXPLAINED

blog article

Apr 08, 2019

When inventor Frederick Banting discovered insulin in 1923, he refused to put his name on the patent. He felt it was unethical for a doctor to profit from a discovery that would save lives. Banting’s co-inventors, James Collip and Charles Best, sold the insulin patent to the University of Toro...

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In Pharma value chain, PBMs manage to benefit IN PHARMA VALUE CHAIN, PBMS MANAGE TO BENEFIT

blog article

Apr 08, 2019

As 2020 Democratic presidential aspirants lean into their game of one-upsmanship on policies that would slow medical progress and undermine the U.S. biopharmaceutical industry, it’s a relief to see the Senate convene a hearing Tuesday on the self-dealing middlemen in the drug delivery system w...

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Diabetes: Could targeting this protein prevent hypoglycemia? DIABETES: COULD TARGETING THIS PROTEIN PREVENT HYPOGLYCEMIA?

blog article

Apr 08, 2019

People with type 1 or type 2 diabetes who take insulin have a higher risk of developing hypoglycemia, or low blood sugar. Now, a study of how a protein works in the pancreas could lead to new treatments for protecting against the potentially life-threatening condition. Researchers may have found a w...

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Leveraging the Role of AI for More Successful Clinical Trials LEVERAGING THE ROLE OF AI FOR MORE SUCCESSFUL CLINICAL TRIALS

blog article

Apr 04, 2019

The pharmaceutical industry spends billions on R&D each year. Clinical trials require tremendous amounts of effort, from identifying sites and enrolling patients to overseeing research functions and coordinating trial logistics. Trials often run over budget or are delayed because of a number of ...

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10 Unusual Applications of CRISPR Gene Editing 10 UNUSUAL APPLICATIONS OF CRISPR GENE EDITING

blog article

Apr 04, 2019

CRISPR has been all over the news in the past couple of years, and with reason. This gene editing tool is making gene editing easier and faster than ever, and the possibilities it has opened go well beyond human health. You might have heard of the tremendous potential CRISPR could have in treating d...

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How a self-learning Ontology benefits Pharma and Life Sciences? HOW A SELF-LEARNING ONTOLOGY BENEFITS PHARMA AND LIFE SCIENCES?

blog article

Apr 03, 2019

Every domain has its own language. The same word used in different domains can have totally different meanings. In fact, the same word can mean two separate things for different subdomains, eg. in science, hedgehog is both animal and protein. Moreover, domain language is dominated by abbreviations a...

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A new wearable device may detect cancer with more precision A NEW WEARABLE DEVICE MAY DETECT CANCER WITH MORE PRECISION

blog article

Apr 01, 2019

Researchers from the University of Michigan have developed and are now testing a device they call "the epitome of precision medicine" that detects cancer in circulating blood. "Nobody wants to have a biopsy," says Dr. Daniel Hayes, the Stuart B. Padnos, Professor of Breast Cancer...

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This drug failed to treat cancer, but it could improve dementia THIS DRUG FAILED TO TREAT CANCER, BUT IT COULD IMPROVE DEMENTIA

blog article

Mar 29, 2019

Dementia — an umbrella term for various neurodegenerative conditions involving memory loss and other forms of cognitive impairment — is hard to treat because its causes remain unknown. Researchers, however, are making painstaking progress. Dr. Kenneth Kosik, the Harriman Professor of Neu...

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Kick-starting the immune response – the shifting landscape of immuno-oncology KICK-STARTING THE IMMUNE RESPONSE – THE SHIFTING LANDSCAPE OF IMMUNO-ONCOLOGY

blog article

Mar 29, 2019

The landscape of cancer treatment has changed dramatically in the last seven years, beginning with the approval of Ipilmumab in 2011, the first immunotherapy drug. Efforts to unsheathe the tumour cells of their protective microenvironment and expose them to an active immune response have delivered s...

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Taking a Closer Look at Microbial-Environmental Interactions With Cryo-EM TAKING A CLOSER LOOK AT MICROBIAL-ENVIRONMENTAL INTERACTIONS WITH CRYO-EM

blog article

Mar 28, 2019

No microbe is an island. Understanding how they interact with each other and their surrounding environment is important to harness their beneficial properties and combat harmful behavior.
Observing microbes at the molecular and even individual protein level can reveal the details of how micro...

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AI and Machine Learning in the European Pharmaceutical Industry AI AND MACHINE LEARNING IN THE EUROPEAN PHARMACEUTICAL INDUSTRY

blog article

Mar 28, 2019

Accenture reports that in 2017, the 16 top biopharmaceutical companies in the world had an aggregate global revenue of $428 billion, which was nearly half the global pharmaceutical market by net sales. The report also revealed a shift to specialty drugs for hard-to-treat diseases. AI has numerous ap...

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How AI could spur drug development HOW AI COULD SPUR DRUG DEVELOPMENT

blog article

Mar 28, 2019

Using artificial intelligence in drug design would give pharmaceutical research a boost, says Gisbert Schneider. In the medium term, computers could even carry out experiments autonomously. Designing drugs is a complex and challenging task. How do you create effective new medicines without adverse s...

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Is this a better way to deliver drugs to the brain? IS THIS A BETTER WAY TO DELIVER DRUGS TO THE BRAIN?

blog article

Mar 28, 2019

The blood-brain barrier is a protective layer that surrounds the brain. Its main function is to prevent potentially harmful agents from leaking into this organ. However, it can also stop certain therapeutic drugs from reaching their target. The blood-brain barrier prevents antitumor drugs and t...

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Knee osteoarthritis: A low-carb diet may relieve symptoms KNEE OSTEOARTHRITIS: A LOW-CARB DIET MAY RELIEVE SYMPTOMS

blog article

Mar 27, 2019

A randomized controlled study finds that a diet low in carbs can relieve pain for people who have knee osteoarthritis. Osteoarthritis is the most widespread form of arthritis among older adults in the United States. Knee osteoarthritis, in particular, affects about 10 percent of men and 13 percent o...

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Why do antidepressants fail for some? WHY DO ANTIDEPRESSANTS FAIL FOR SOME?

blog article

Mar 27, 2019

Research has revealed a biological explanation for why some people with depression do not respond to a class of antidepressants that doctors commonly prescribe. It has to do with fundamental differences in the nerve cells that produce and use serotonin.

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India aspiring malaria-free status: the long and short of it INDIA ASPIRING MALARIA-FREE STATUS: THE LONG AND SHORT OF IT

blog article

Mar 26, 2019

India is historically a malaria endemic country. It holds the distinction of being the site of the discovery by Noble Prize winner Sir Ronal Ross that established the malaria parasite cycle through Anopheles mosquitoes as the definitive host, and the spectacular success of malaria control during the...

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How to Kick the Bad Habit of Smoking with Ayurveda HOW TO KICK THE BAD HABIT OF SMOKING WITH AYURVEDA

blog article

Mar 26, 2019

Smoking is bad for the health of the smoker as well as those surrounding him. The cigarette is said to have over 600 ingredients in them which includes harmful substances such as carbon monoxide, formaldehyde, lead, acetone, and tar, etc. Since smoking is known to cause serious health ailments like ...

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Why your household dust could fuel the growth of fat cells WHY YOUR HOUSEHOLD DUST COULD FUEL THE GROWTH OF FAT CELLS

blog article

Mar 26, 2019

Researchers have found that the dust in our households may harbor numerous chemicals that may accelerate the development of fat cells, potentially contributing to obesity. In recent years, researchers and international policymakers have expressed concerns about the effects of endocrine-disrupti...

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Keto diet: New study unearths sex differences KETO DIET: NEW STUDY UNEARTHS SEX DIFFERENCES

blog article

Mar 26, 2019

In recent years, the ketogenic diet has become increasingly popular with people who want to lose weight quickly. A new study asks whether this dietary pattern works as well in females as it does in males. Experts originally designed the ketogenic diet, which people often refer to as the keto diet, a...

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5 Second Squeeze Test Provides Snapshot of Groin Function 5 SECOND SQUEEZE TEST PROVIDES SNAPSHOT OF GROIN FUNCTION

blog article

Mar 26, 2019

Five seconds is enough to assess the status of a hockey player’s groin. For the first time, a simple field test called the five-second squeeze test, has been used on ice-hockey players to see if it can indicate current hip/groin function and hip muscle strength. According to the new study from...

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Can You “Catch” Cancer? CAN YOU “CATCH” CANCER?

blog article

Mar 26, 2019

Billions worldwide are infected with tropical worms. Unsurprisingly, most of these people live in poor countries, kept poor by the effects of worm-related malnourishment. What may surprise many is that worms also cause the majority of cases of some cancers in these countries. Published in Frontiers ...

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B Vitamins Slow Alzheimer B VITAMINS SLOW ALZHEIMER'S AND GREY MATTER LOSS

blog article

Mar 25, 2019

The researchers – from Oxford's Nuffield Department of Clinical Neurosciences - conducted a clinical trial with 156 elderly patients who had mild cognitive impairment and a high risk of dementia and Alzheimer's disease. The researchers randomized the patients and for two years, gave on...

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Anatomy of a Science Study Censorship ANATOMY OF A SCIENCE STUDY CENSORSHIP

blog article

Mar 25, 2019

It's not often that veterinary research is so controversial that it falls into the jaws of censorship zealots. That is exactly what happened recently, however, when editors at a science journal suddenly turned on a small Spanish sheep study which they had already peer-reviewed and published and ...

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Ketogenic Diet May Not Be Beneficial for Females KETOGENIC DIET MAY NOT BE BENEFICIAL FOR FEMALES

blog article

Mar 25, 2019

The ketogenic diet recently has been touted for weight loss and improving blood sugar control, but a new study finds that females fail to show these metabolic benefits on this high-fat, very low-carbohydrate diet. Results of the animal study will be presented Sunday, March 24 at the Endocrine Societ...

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Calculating Gestational Age With Metabolomics CALCULATING GESTATIONAL AGE WITH METABOLOMICS

blog article

Mar 25, 2019

Sadly, preterm death is one of the leading causes of death among children under five years of age. To develop a solution, it is imperative that scientists can measure the extent of the issue at a population level across the globe. In underdeveloped countries where pregnant women do not have routine ...

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Why too much vitamin D can be a bad thing WHY TOO MUCH VITAMIN D CAN BE A BAD THING

blog article

Mar 25, 2019

A new study on the effects of vitamin D found that too much may lead to slower reaction times and increase the risk of falling among older people. Vitamin D is an essential vitamin that helps build and maintain healthy bones and teeth. Without this, our bodies cannot absorb calcium, which is the mai...

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6 Real-World Uses for IoT in the Pharma Industry 6 REAL-WORLD USES FOR IOT IN THE PHARMA INDUSTRY

blog article

Mar 25, 2019

In an Internet of Things (IoT) world, objects – from doorknobs to pill capsules – have computerized eyes and brains which can talk to each other and to us. That might sound like the beginning of a sci-fi horror story, but what it actually means is that there are more sources of useful in...

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Cystic fibrosis: Existing drug may improve lung function CYSTIC FIBROSIS: EXISTING DRUG MAY IMPROVE LUNG FUNCTION

blog article

Mar 24, 2019

Researchers say a drug that is already available on the market can help those affected by cystic fibrosis. Amphotericin, which is an antifungal medication, might help people with cystic fibrosis fight the chronic bacterial lung infections that tend to occur with this disease, according to a rec...

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One Serving of Greens Daily Slows Brain Aging by Over a Decade ONE SERVING OF GREENS DAILY SLOWS BRAIN AGING BY OVER A DECADE

blog article

Mar 24, 2019

Are memory loss and decreased brain power inevitable as we age? Many people in their 40s, 50s and beyond are told that it is and there is nothing that can be done about it. Is that true? Of course, not Steps can be taken to not only stop memory loss but also reverse it. Here is a simple step. New re...

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Could prescription vegetables be the future of healthcare? COULD PRESCRIPTION VEGETABLES BE THE FUTURE OF HEALTHCARE?

blog article

Mar 23, 2019

The authors of a new study conclude that healthful food prescriptions in Medicare and Medicaid would be more cost-effective after 5 years than preventive drug treatments. Medicare and Medicaid are the two largest healthcare programs in the United States. Approximately 57 million people received cove...

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To Reach Mars, We Need Biotechnology TO REACH MARS, WE NEED BIOTECHNOLOGY

blog article

Mar 23, 2019

As we prepare for long-distance space travel and life on Mars, biotechnology could be the only possible solution to make spaceships no longer dependent on Earth’s constant supply. “As human beings, we need a constant supply of oxygen. We need constant access to nutritious food, clean wat...

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Post-translational Modifications in Biopharmaceuticals POST-TRANSLATIONAL MODIFICATIONS IN BIOPHARMACEUTICALS

blog article

Mar 22, 2019

The growing market for biopharmaceuticals1 brings new challenges for drug developers and manufacturers in assuring product quality and safety, and much of this can be attributed to product variability caused by post-translational modifications (PTMs).

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Can we treat leishmaniasis with tiny magnets? CAN WE TREAT LEISHMANIASIS WITH TINY MAGNETS?

blog article

Mar 22, 2019

Cutaneous leishmaniasis (CL) remains one of the most neglected of the neglected tropical diseases or NTDs. CL is caused by infection with the protozoan parasite Leishmania which is spread by the bite of an infected sand fly and resides inside human macrophages.

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Brexit’s effect on the biopharmaceutical lifecycle BREXIT’S EFFECT ON THE BIOPHARMACEUTICAL LIFECYCLE

blog article

Mar 21, 2019

Despite the nature of this event, there is still a great deal of uncertainty around how it will happen, when and if indeed it will happen at all. Add to this that there is still no real clarity on the consequences of Brexit if and when it happens not for the public, not for businesses, and certainly...

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Paving the path towards precision medicine PAVING THE PATH TOWARDS PRECISION MEDICINE

blog article

Mar 21, 2019

University of Otago scientists have discovered a way to view the immune cell ‘landscape’ of bowel cancer tumors, paving the way towards more individualized medicine and treatment for many other diseases in the future. The scientists have shown the incredible diversity of immune cells tha...

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Poor Sleep Linked To Cardiovascular Disease POOR SLEEP LINKED TO CARDIOVASCULAR DISEASE

blog article

Mar 21, 2019

If you’ve spoken with your doctor about protecting your heart health, you likely received advice about eating well and starting an exercise routine. But a recent study suggests there’s another way to help: get a good night’s sleep. Previous research has suggested a link between poo...

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Drug discovery from the age of information to the age of intelligence DRUG DISCOVERY FROM THE AGE OF INFORMATION TO THE AGE OF INTELLIGENCE

blog article

Mar 20, 2019

Data drives drug discovery, yet it continues to be among the biggest challenges faced by the industry. Experiments are often not repeatable and data interpretation is subject to the biases and limitations of human beings. There are many reasons that molecules fail to become marketed drugs. In o...

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Big Data in Pharmaceutical: Top Trends Transforming Medicine BIG DATA IN PHARMACEUTICAL: TOP TRENDS TRANSFORMING MEDICINE

blog article

Mar 20, 2019

After transforming the face of Marketing, Sales, and Service, Big Data is extending its reach and impact into other industries. While industries such as Automation, Oil and Gas, Metallurgy, Military, Education, and Hospitality have been faster than the rest in adopting and promoting Big Data applica...

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10 minutes of leisurely activity per week may lower death risk 10 MINUTES OF LEISURELY ACTIVITY PER WEEK MAY LOWER DEATH RISK

blog article

Mar 20, 2019

New research suggests that adults over the age of 40 who engage in leisurely physical activity such as dancing, gardening, or going for a walk for even a short amount of time each week may have a lower risk of death from multiple causes. Previous research has shown that engaging even in low-lev...

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Scanning Study a Stepping Stone for Cognitive Impairment Research SCANNING STUDY A STEPPING STONE FOR COGNITIVE IMPAIRMENT RESEARCH

blog article

Mar 20, 2019

Using strong and targeted but noninvasive magnets at specific sites in the brains of people with and without mild learning and memory problems, Johns Hopkins researchers report they were able to detect differences in the concentrations of brain chemicals that transmit messages between neurons. The s...

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Mass Spec Study Backs Remarkable Parkinson MASS SPEC STUDY BACKS REMARKABLE PARKINSON'S SMELL TEST

blog article

Mar 20, 2019

A skin swab test for Parkinson's has become a real possibility after mass spectrometry was used to detect altered levels of specific compounds on the skin of people with the condition. The research is a result of the incredible ability of one woman to detect a unique odor on the skin of people w...

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Heart disease and depression: Scientists find missing link HEART DISEASE AND DEPRESSION: SCIENTISTS FIND MISSING LINK

blog article

Mar 19, 2019

Researchers already recognized the link between depression and heart disease. However, until recently, the mechanisms explaining it remained a mystery. A new study reveals that stress-induced inflammation may explain why mental and cardiovascular health is so intimately related.

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Light and sound therapy may boost brain function LIGHT AND SOUND THERAPY MAY BOOST BRAIN FUNCTION

blog article

Mar 19, 2019

New research in mice reveals that an innovative light and sound stimulation therapy can clear toxic plaque buildup in the brain and reduce some of the symptoms of Alzheimer's disease and impaired cognitive functioning. The hallmarks of Alzheimer's disease in the brain include the format...

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What causes a red spot on the eye? WHAT CAUSES A RED SPOT ON THE EYE?

blog article

Mar 19, 2019

A red spot on the eye may look worrying, but it is rarely a medical emergency. Usually, a red spot on the eye occurs when blood collects under the conjunctiva due to a subconjunctival hemorrhage. The conjunctiva is the transparent membrane that covers the surface of the eye. The conjunctiva contains...

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Flow Chemistry: Successfully Transitioning From Lab to Production FLOW CHEMISTRY: SUCCESSFULLY TRANSITIONING FROM LAB TO PRODUCTION

blog article

Mar 19, 2019

As continuous flow technology takes center stage, we are seeing a transformation in chemical production. To learn more about the transition away from batch-wise approaches to chemical reactions, the advantages, and challenges of using flow technology, and how its adoption has impacted the industry w...

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Doctors Reverse Decades Old Aspirin Recommendation: Deadly Risks Outweigh Benefits for Heart Disease & Stroke DOCTORS REVERSE DECADES OLD ASPIRIN RECOMMENDATION: DEADLY RISKS OUTWEIGH BENEFITS FOR HEART DISEASE & STROKE

blog article

Mar 19, 2019

New cardiovascular disease prevention guidelines submitted jointly by the American College of Cardiology and the American Heart Associated and published in the Journal of the American College of Cardiology contradict decades of routine medical advice by explicitly advising against the daily use of l...

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How destroying a tumor promoter could lead to new cancer treatments HOW DESTROYING A TUMOR PROMOTER COULD LEAD TO NEW CANCER TREATMENTS

blog article

Mar 19, 2019

Scientists have cracked a cell mechanism that drives tumor formation in most types of cancer. This finding could lead to much-needed new therapies for cancer, including the hard-to-treat triple-negative breast cancer. The discovery concerns the molecular activity of the tumor suppressor protein...

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Refugee Women Have Healthier Pregnancies Than US Women — Why? An Unhealthy US Culture REFUGEE WOMEN HAVE HEALTHIER PREGNANCIES THAN US WOMEN — WHY? AN UNHEALTHY US CULTURE

blog article

Mar 19, 2019

African refugee women experience healthier pregnancies than women born in the United States, despite receiving less prenatal care, found a recent University at Buffalo study. Compared to U.S.-born black and white women, African refugee women had fewer pre-pregnancy health risks, fewer preterm births...

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Unique Gene Mutations in Hereditable Heart Disease UNIQUE GENE MUTATIONS IN HEREDITABLE HEART DISEASE

blog article

Mar 19, 2019

In a new study from the Intermountain Healthcare Heart Institute in Salt Lake City, researchers have identified eight new gene mutations that may cause or contribute to idiopathic dilated cardiomyopathy, a form of heart disease not caused by known external influences, such as high blood pressure, ob...

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Cell line development global market drivers, trends and its impact on improving biologics development from early phase CELL LINE DEVELOPMENT GLOBAL MARKET DRIVERS, TRENDS AND ITS IMPACT ON IMPROVING BIOLOGICS DEVELOPMENT FROM EARLY PHASE

blog article

Mar 19, 2019

Cell line development is a major step for examining the efficiency of drug discovery, toxicity, and in-vitro testing. It reduces time, effort and cost, which minimizes the chance of research drugs failing at the clinical trial stage. This stage involves the production of recombinant proteins such as...

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Doctors could detect brain disorders in seconds with sensor DOCTORS COULD DETECT BRAIN DISORDERS IN SECONDS WITH SENSOR

blog article

Mar 19, 2019

Using nanotechnology, UCF researchers have developed the first rapid detector for dopamine, a chemical that is believed to play a role in various diseases such as Parkinson's, depression and some cancers. Studies show too much dopamine could be associated with some cancers, while low dopamine co...

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THE PROTECTIVE EFFECT OF GILBERT SYNDROME THE PROTECTIVE EFFECT OF GILBERT SYNDROME

blog article

Mar 19, 2019

Rare diseases do not always lead to restricted and shorter life spans. Sometimes they can actually help improve survival. Not everyone suffering from a rare disease faces a debilitated or shorter life. Consider Gilbert syndrome (GS), a hereditary condition that is usually mild and, ironically, a pro...

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Direct-to-Stomach Drug Release Could Reduce TB Burden DIRECT-TO-STOMACH DRUG RELEASE COULD REDUCE TB BURDEN

blog article

Mar 19, 2019

Tuberculosis is one of the world’s deadliest infectious diseases: One-third of the world’s population is infected with TB, and more than 1 million people die from the disease every year. One reason TB is so pervasive is that treatment requires a six-month course of daily antibiotics, whi...

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Do standing desks really help you lose weight? DO STANDING DESKS REALLY HELP YOU LOSE WEIGHT?

blog article

Mar 19, 2019

New research, published in the journal Applied Ergonomics, reviews the health benefits of sit-stand desks. Heart disease, cancer, type 2 diabetes, obesity, and premature death are only some of the adverse effects associated with a sedentary lifestyle. A recent study found that excessive sitting may ...

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Study Ties Common Heartburn Medications to Kidney Disease STUDY TIES COMMON HEARTBURN MEDICATIONS TO KIDNEY DISEASE

blog article

Mar 19, 2019

Common medications prescribed to treat heartburn, acid reflux and ulcers are linked to increased risks for kidney failure and chronic kidney disease, found a recent University at Buffalo study. Use of proton pump inhibitors (PPI), a group of drugs that reduce the production of stomach acid, increase...

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7 Artificial Intelligence Pharma Applications You Should Be Aware of in 2019 7 ARTIFICIAL INTELLIGENCE PHARMA APPLICATIONS YOU SHOULD BE AWARE OF IN 2019

blog article

Mar 19, 2019

Artificial intelligence (AI) has turned into a great tool for the pharma industry. It’s helping with drug discovery, rare disease detection, high-quality analytics, clinical trial patient enrollment, personalized patient care and more. According to Statista, artificial intelligence revenue fro...

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3 trends in lab procurement strategies for life science organizations 3 TRENDS IN LAB PROCUREMENT STRATEGIES FOR LIFE SCIENCE ORGANIZATIONS

blog article

Mar 18, 2019

As a procurement planner in the competitive life sciences sector, how do you ensure your organization adapts swiftly to the rapidly changing demands of customers and stakeholders? Whether supporting a CRO, pharmaceutical company, clinical lab, biotech business or academic department, procurement tea...

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Artificial Intelligence – A boon to Pharmaceuticals and Healthcare ARTIFICIAL INTELLIGENCE – A BOON TO PHARMACEUTICALS AND HEALTHCARE

blog article

Mar 18, 2019

Over the last few years, Artificial Intelligence and Machine learning have become widely discussed topics in the area of pharmaceuticals, healthcare and life sciences. A lot of pharmaceuticals companies and healthcare organizations express significant interests in possible new opportunities associat...

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The 15 Biotech Companies in Portugal You Should Know THE 15 BIOTECH COMPANIES IN PORTUGAL YOU SHOULD KNOW

blog article

Mar 18, 2019

Portugal has a rich biotech ecosystem that is rapidly growing, despite sometimes being ovelooked compared with other countries in Europe. These are the companies driving forth innovation in the country.  In recent years, the biotech industry has boomed in Portugal, with some big success stories...

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Lab Automation In-Depth Focus 2019 LAB AUTOMATION IN-DEPTH FOCUS 2019

blog article

Mar 18, 2019

In this In-Depth Focus: realising the promise of laboratory automation in biomedical research, drug discovery from the age of information to the age of intelligence, and transforming drug discovery, development and delivery with flow chemistry.

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Groundbreaking blood test detects fibromyalgia GROUNDBREAKING BLOOD TEST DETECTS FIBROMYALGIA

blog article

Mar 18, 2019

New research finds an accurate way of diagnosing fibromyalgia and differentiating it from other related conditions. Using blood samples and innovative techniques, scientists have detected a "molecular fingerprint" that is unique to the condition. Fibromyalgia is a chronic condition th...

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Common blood pressure drug may increase cardiac arrest risk COMMON BLOOD PRESSURE DRUG MAY INCREASE CARDIAC ARREST RISK

blog article

Mar 18, 2019

A preliminary study concludes that a drug that doctors commonly prescribe to treat angina and blood pressure might increase the risk of sudden cardiac arrest. Cardiac arrest occurs when the heart stops pumping blood around the body. If a person does not receive treatment, cardiac arrest can be ...

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Alzheimer ALZHEIMER'S DISEASE: AN EYE TEST COULD PROVIDE EARLY WARNING

blog article

Mar 18, 2019

In the future, a doctor might be able to tell whether someone is heading toward Alzheimer's disease not by carrying out expensive brain scans, but during an eye exam. A new study paper in the journal Ophthalmology Retina outlines research that took place at Duke Eye Center in Durham, NC. The res...

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TRENDING TOPICS: ARTIFICIAL INTELLIGENCE TRENDING TOPICS: ARTIFICIAL INTELLIGENCE

blog article

Mar 18, 2019

Artificial intelligence (AI) is a hot topic in the research world, and for good reason. The promises made by AI optimists are exciting, from AI drug discovery to robot doctors as good as any human physician. AI pessimists are quick to point out that we have a long, maybe impossibly long, way to go b...

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Bridging The Policy-Practice Divide In Genome-Editing For Agriculture BRIDGING THE POLICY-PRACTICE DIVIDE IN GENOME-EDITING FOR AGRICULTURE

blog article

Mar 18, 2019

Regulation of emerging technology such as genome editing has mainly focused on responding to the consequences of innovation. The classical regulatory model of “identification-quantification-assessment-safety management” takes a risk-oriented approach to regulation of emerging technology ...

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Coffee chemicals could curb prostate cancer COFFEE CHEMICALS COULD CURB PROSTATE CANCER

blog article

Mar 18, 2019

Following a series of experiments, researchers conclude that two compounds found in coffee might help slow the growth of prostate cancer cells. Although the findings are preliminary, they are encouraging. Coffee is one of the most popular drinks on the planet and is a complex cocktail. In fact, coff...

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Can maternal exposure to carbon black nanoparticles affect male fertility? CAN MATERNAL EXPOSURE TO CARBON BLACK NANOPARTICLES AFFECT MALE FERTILITY?

blog article

Mar 18, 2019

Carbon black nanoparticles are manufactured for use in rubber products, as a color pigment in plastics, paint, and ink and used to model exposure to air pollution particles. These particles have been shown to have toxic effects and previous mice studies have shown that maternal exposure can affect t...

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Recruitment of pregnant women in randomized trials: What could hold us back? RECRUITMENT OF PREGNANT WOMEN IN RANDOMIZED TRIALS: WHAT COULD HOLD US BACK?

blog article

Mar 18, 2019

For many years, members of the Dutch Consortium for Healthcare Evaluation and Research in Obstetrics and Gynecology (NVOG Consortium) have been working on the improvement of care for patients with threatened preterm birth. One of the research topics, the safety, and effectiveness of labor-suppressin...

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Higher cholesterol, egg consumption linked to heart disease HIGHER CHOLESTEROL, EGG CONSUMPTION LINKED TO HEART DISEASE

blog article

Mar 18, 2019

A recent study has linked higher consumption of eggs or dietary cholesterol to a higher risk of cardiovascular disease and premature death. The finding is likely to rekindle the debate on eggs and heart health. For example, the new study seems to contradict the decision in the United States to ...

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Cosmetic surgery is on the rise, new data reveal COSMETIC SURGERY IS ON THE RISE, NEW DATA REVEAL

blog article

Mar 17, 2019

The American Society of Plastic Surgeons has published new statistics that reveal recent trends in body-shaping procedures. According to the American Society of Plastic Surgeons (ASPS), almost 18 million people underwent surgical and minimally invasive cosmetic procedures in the United States i...

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Skin moisturizer could reduce risk of disease SKIN MOISTURIZER COULD REDUCE RISK OF DISEASE

blog article

Mar 17, 2019

According to a small pilot study, moisturizing our skin might reduce the risk of developing a range of chronic conditions, including heart disease, diabetes, and even Alzheimer's disease. The skin is our largest organ. One of its primary functions, of course, is to protect our insides from the d...

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Metagenomics may provide answers to irritable bowels, asthma attacks and body odor METAGENOMICS MAY PROVIDE ANSWERS TO IRRITABLE BOWELS, ASTHMA ATTACKS AND BODY ODOR

blog article

Mar 16, 2019

The "first" genomics era began with the landmark Human Genome Project, which launched in 1990 and was completed in 2003, leading to the sequencing of the 20,000-25,000 human genes. It gave birth to an omics revolution and, by necessity, a series of increasingly sophisticated technologies a...

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HOW READY ARE YOUR CLEANROOMS FOR ANNEX 1 UPDATES? HOW READY ARE YOUR CLEANROOMS FOR ANNEX 1 UPDATES?

blog article

Mar 15, 2019

More than 10 years have passed since the last revision of the Annex 1 of the EU GMP Guideline for the manufacture of sterile medicinal products. With the revised document set for release later on this year, the updates significantly impact QC/QA and all laboratory activities, more so now than in pre...

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Green Tea Cuts Obesity, Health Risks In Mice GREEN TEA CUTS OBESITY, HEALTH RISKS IN MICE

blog article

Mar 15, 2019

Green tea cut obesity and a number of inflammatory biomarkers linked with poor health in a new study. Mice fed a diet of 2 percent green tea extract fared far better than those that ate a diet without it, a finding that has prompted an upcoming study of green tea’s potential benefits in people...

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Manganese and Parkinson MANGANESE AND PARKINSON'S: MECHANISM MAY EXPLAIN LINK

blog article

Mar 15, 2019

New research, published in the journal Science Signaling, details the mechanism through which exposure to manganese can trigger protein misfolding in the brain which may, in turn, lead to Parkinson's-like symptoms. The findings may enable an earlier diagnosis of the neurological condition.

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Lower Brain Connectivity Makes the Working Day Tougher for Night Owls LOWER BRAIN CONNECTIVITY MAKES THE WORKING DAY TOUGHER FOR NIGHT OWLS

blog article

Mar 15, 2019

Did you wake up bright and bushy-tailed this World Sleep Day? Or did you throw your slippers at your 6.30AM alarm and then fall back asleep whilst having a shower? If the latter option seems more familiar, you might consider yourself a night owl. New research from the University of Birmingham explai...

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Brain Wave Stimulation May Improve Alzheimer’s Symptoms BRAIN WAVE STIMULATION MAY IMPROVE ALZHEIMER’S SYMPTOMS

blog article

Mar 15, 2019

By exposing mice to a unique combination of light and sound, MIT neuroscientists have shown that they can improve cognitive and memory impairments similar to those seen in Alzheimer’s patients. This noninvasive treatment, which works by inducing brain waves known as gamma oscillations, also gr...

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Agilent Aids Infant Nutrition AGILENT AIDS INFANT NUTRITION

blog article

Mar 14, 2019

Undernutrition contributes to almost half of all deaths in children under the age of five. (WHO) Agilent is helping to counteract this in a highly innovative way. The World Health Organization recommends to exclusively breastfeed babies from birth to six months of age. (WHO).  This would provid...

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New PTSD blood test could aid prevention and treatment NEW PTSD BLOOD TEST COULD AID PREVENTION AND TREATMENT

blog article

Mar 14, 2019

Breakthrough research has yielded a cluster of genetic markers that could form the basis of a blood test for PTSD. Scientists at the Indiana University School of Medicine in Indianapolis suggest that their findings could lead to more accurate diagnoses of post-traumatic stress disorder (PTSD). "...

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Ovarian cancer: New drug may prevent recurrence OVARIAN CANCER: NEW DRUG MAY PREVENT RECURRENCE

blog article

Mar 14, 2019

New research in mice identifies a compound that prevents ovarian cancer recurrence by eradicating the cancer stem-like cells that conventional chemotherapy leaves behind. According to the National Cancer Institute, there were over 22,000 new cases of ovarian cancer in the United States in 2018....

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Non-invasive imaging for small airway lung disease NON-INVASIVE IMAGING FOR SMALL AIRWAY LUNG DISEASE

blog article

Mar 14, 2019

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the US, with approximately 16 million Americans currently affected. Researchers at the University of Michigan have reported on the ability of Parametric Response Mapping (PRM), a relatively new technique, to identif...

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Napping may be as good as drugs for lowering blood pressure NAPPING MAY BE AS GOOD AS DRUGS FOR LOWERING BLOOD PRESSURE

blog article

Mar 13, 2019

A midday nap may be just what you need, not just to boost your energy levels but also to lower high blood pressure. This, at least, is what new research from Greece suggests. When the afternoon slump hits in the middle of a busy workday, many of us may feel tempted to catch some shut-eye in a q...

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Could Alzheimer COULD ALZHEIMER'S BE A REACTION TO INFECTION?

blog article

Mar 13, 2019

What do people fear the most about getting old? The answer is Alzheimer’s disease. Indeed, a 2014 poll conducted in the United Kingdom found that two-thirds of people over the age of 50 were worried about developing dementia, which primarily manifests in the form of Alzheimer’s disease, ...

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Righting the gender imbalance in autism studies RIGHTING THE GENDER IMBALANCE IN AUTISM STUDIES

blog article

Mar 13, 2019

Autism doesn’t just affect boys and men, but research on the condition still predominantly focuses on them. Some scientists are finally beginning to include women and nonbinary people in their studies.

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Seven security considerations when implementing cloud-based laboratory analytics SEVEN SECURITY CONSIDERATIONS WHEN IMPLEMENTING CLOUD-BASED LABORATORY ANALYTICS

blog article

Mar 13, 2019

Automated lab analytics solutions are increasingly taking to the cloud to give labs real-time visibility of instrument and consumables usage. This is valuable information – for example to understand what throughput is available to scale up and complete programs in weeks and hours rather than m...

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How the cloud will change the pharmaceutical industry HOW THE CLOUD WILL CHANGE THE PHARMACEUTICAL INDUSTRY

blog article

Mar 13, 2019

How the cloud in particular stands to shift the pharmaceutical industry and why these changes are so important for its future. The speed of cloud adoption has varied across industries, and whilst financial services and manufacturing are still lagging, healthcare and pharmaceuticals, after years of r...

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Big Data in Pharma and Life Sciences – AI and Data Management BIG DATA IN PHARMA AND LIFE SCIENCES – AI AND DATA MANAGEMENT

blog article

Mar 13, 2019

We’ve spoken to many leaders in healthcare and pharma over the last half a decade, and when it comes to AI, the most pressing challenge that healthcare and pharma leaders report is that they’re unsure of how to streamline and structure their data in a way that lets them build machine lea...

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NGS library prep and QC: Five expert tricks to save time and money NGS LIBRARY PREP AND QC: FIVE EXPERT TRICKS TO SAVE TIME AND MONEY

blog article

Mar 12, 2019

Next-generation sequencing (NGS) is helping to advance genomics research at an unprecedented rate. However, the process can be technically challenging, and any errors can significantly impact the reliability and accuracy of your results. NGS library preparation and QC can have a major impact on your...

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Stem Cells and Hydrogel Make Potential Osteoarthritis Treatment STEM CELLS AND HYDROGEL MAKE POTENTIAL OSTEOARTHRITIS TREATMENT

blog article

Mar 12, 2019

Scientists from the Netherlands have received a €600,000 grant to test a treatment for osteoarthritis in humans that combines hydrogels and stem cells to help the knee joint heal. In osteoarthritis, the cartilage in joints such as the knees breaks down, causing stiffness and pain. There is no c...

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Blocking Hidden Viral Protein Shows Promise for Treating Multiple Sclerosis BLOCKING HIDDEN VIRAL PROTEIN SHOWS PROMISE FOR TREATING MULTIPLE SCLEROSIS

blog article

Mar 12, 2019

An antibody that blocks the action of a hidden viral protein encoded by our genome shows encouraging signs of slowing down the progression of multiple sclerosis, according to the Swiss biotech GeNeuro which carried out the research. GeNeuro’s monoclonal antibody drug targets the hidden viral p...

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12 Fascinating Benefits and Uses of Basil Seeds 12 FASCINATING BENEFITS AND USES OF BASIL SEEDS

blog article

Mar 12, 2019

Basil seeds aren’t just for growing basil plants you can also eat them. They look similar to sesame seeds but are black. The type that you eat typically comes from sweet basil, Ocimum basilicum, which is the plant commonly used to season foods. For this reason, the seeds are typically referred...

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Sleep loss can turn us into social outcasts SLEEP LOSS CAN TURN US INTO SOCIAL OUTCASTS

blog article

Mar 12, 2019

When we sleep poorly, we may feel less inclined to participate in social activities. Now, researchers have found evidence that being sleep-deprived can not only make us less sociable, but it can also prevent our peers from seeking us out. Sleep deprivation can contribute to a host of mental and...

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The Mediterranean diet can boost athletic performance in just 4 days THE MEDITERRANEAN DIET CAN BOOST ATHLETIC PERFORMANCE IN JUST 4 DAYS

blog article

Mar 12, 2019

New research, published in the Journal of the American College of Nutrition, finds that adhering to the Mediterranean diet for just 4 days is enough to boost exercise performance. The Mediterranean diet offers a range of benefits, from cardioprotective effects to staving off chronic disease. As...

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New drug limits damage to heart muscle from heart attack NEW DRUG LIMITS DAMAGE TO HEART MUSCLE FROM HEART ATTACK

blog article

Mar 11, 2019

An experimental drug has shown great promise in limiting the damage that a heart attack can inflict on the heart. It targets a protein that plays a central role in the death of heart muscle cells. Tests on mice have revealed that the drug could markedly reduce heart injury from a heart attack.

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What to know about the lemon detox diet WHAT TO KNOW ABOUT THE LEMON DETOX DIET

blog article

Mar 11, 2019

The lemon detox diet involves consuming just a lemon juice-based mixture for 1 or 2 weeks, with no solid foods. The diet aims to remove toxins and cleanse the body. However, scientists have found no evidence to support these claims, and the diet may be harmful in some cases.

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Diabetes: Could muscle strength lower risk? DIABETES: COULD MUSCLE STRENGTH LOWER RISK?

blog article

Mar 11, 2019

Many people worldwide have type 2 diabetes, a metabolic condition in which the body cannot properly regulate blood sugar levels. Experts already know that lack of physical activity can contribute to the risk of diabetes, but what type of exercise might lower it? Recently, researchers have been ...

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Are Unisom and vitamin B-6 safe during pregnancy? ARE UNISOM AND VITAMIN B-6 SAFE DURING PREGNANCY?

blog article

Mar 11, 2019

Many pregnant women take vitamin B-6 and Unisom to treat morning sickness. In the past, some people had concerns that this combination may harm the fetus. Morning sickness is very common during early pregnancy. Although people often refer to nausea and vomiting during pregnancy as "morning sick...

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Vascular risk factors tied to brain health VASCULAR RISK FACTORS TIED TO BRAIN HEALTH

blog article

Mar 11, 2019

New research uncovers a host of vascular risk factors that may affect the health of our brains as we get older. It is no secret that the global population is aging at an increasingly fast pace. According to the World Health Organization (WHO), there were approximately 900 million people across ...

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Many Families With High Breast Cancer Risk Await a Genetic Explanation MANY FAMILIES WITH HIGH BREAST CANCER RISK AWAIT A GENETIC EXPLANATION

blog article

Mar 11, 2019

For decades, Piri Welcsh has had professional and personal stakes in understanding the genetics of breast cancer. In the 1990s, the molecular geneticist participated in an international race to clone BRCA1, the first gene linked to breast cancer risk, and she works to this day in the lab of pioneeri...

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Precision Drugs Could Unmask Cancers to the Immune System PRECISION DRUGS COULD UNMASK CANCERS TO THE IMMUNE SYSTEM

blog article

Mar 11, 2019

Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients benefit from immunotherapy, a new study reveals. Scientists found that PARP inhibitors sparked a powerful immune response when used against cancer cells with ...

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Care Home Dehydration Tests Inadequate CARE HOME DEHYDRATION TESTS INADEQUATE

blog article

Mar 11, 2019

Standard tests used to identify dehydration are not working for older people living in care homes – according to new research from the University of East Anglia. Carers often use simple tests to see if an older person is dehydrated. These include looking at their eyes, skin, or asking if someo...

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Colorectal Cancer in Patients With Early Onset Is Distinct From That in Older Patients COLORECTAL CANCER IN PATIENTS WITH EARLY ONSET IS DISTINCT FROM THAT IN OLDER PATIENTS

blog article

Mar 11, 2019

New research indicates that colorectal cancer diagnosed at an early age has clinical and genetic features that are different from those seen in traditional colorectal cancer diagnosed later in life. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study a...

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The Time is Now to Control Typhoid THE TIME IS NOW TO CONTROL TYPHOID

blog article

Mar 11, 2019

Each year there are nearly 11 million cases of typhoid, a disease that is spread through contaminated food, drink, and water. Researchers at the University of Maryland School of Medicine are leading an international consortium that is studying the impact of a typhoid conjugate vaccine (TCV) in an ef...

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Post-concert Deafness Explained POST-CONCERT DEAFNESS EXPLAINED

blog article

Mar 11, 2019

When we listen to loud sounds, like at a music concert, our hearing may become impaired for a short time. Researchers at Linköping University have discovered a mechanism that helps to explain how this happens. “Most people have experienced that their hearing is impaired and the ear feels ...

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The Three Steps Needed to Fully Automate the Artificial Pancreas THE THREE STEPS NEEDED TO FULLY AUTOMATE THE ARTIFICIAL PANCREAS

blog article

Mar 11, 2019

New advances in diabetes research are making it possible to develop a fully automated insulin delivery system that can control blood sugar without any input from the patient. This so-called artificial pancreas could be here within the next decade, but there are still three main challenges that scien...

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Divide and conquer: Colorectal Cancer Awareness Month DIVIDE AND CONQUER: COLORECTAL CANCER AWARENESS MONTH

blog article

Mar 08, 2019

March is Colorectal Cancer Awareness Month. Colorectal cancer (CRC), also known as bowel cancer, is the second highest cause of death in Europe. Although we are now better at diagnosing the disease at an earlier stage through the bowel screening program and have made improvements in surgical methods...

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Innovative, More Cost-effective Method to Make Drugs INNOVATIVE, MORE COST-EFFECTIVE METHOD TO MAKE DRUGS

blog article

Mar 08, 2019

The Food and Drug Administration wants the pharmaceutical industry to get away from making drugs using the traditional batch method and switch to a more modern process known as continuous manufacturing. The FDA put out a statement on Feb. 26 saying the continuous process allows manufacturers to more...

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International Women INTERNATIONAL WOMEN'S DAY: INSPIRING YOUNG MINDS AND SAFE SCIENCE WITH CHARLOTTE MAUGHAN

blog article

Mar 08, 2019

Happy International Women's Day! This date has its origins back in the early 1900s when women were marching for voting rights and better working rights. In 1909, the first National Women's Day was observed in the U.S. From that point on, more countries began to observe the day and it was off...

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Could a smartphone app detect diabetes? COULD A SMARTPHONE APP DETECT DIABETES?

blog article

Mar 08, 2019

Today, millions of people in the United States are unaware that they have diabetes. A recent study finds that data from a readily available smartphone app could help detect diabetes in people without requiring a trip to the clinic.

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Cancer: Does mental health influence a person CANCER: DOES MENTAL HEALTH INFLUENCE A PERSON'S OUTLOOK?

blog article

Mar 08, 2019

New research that now appears in the British Journal of Cancer suggests that a person's history of mental health issues may raise their risk of dying from cancer following diagnosis. Though the cancer mortality rates in the United States have "declined steadily" during the past 20...

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10 Natural Remedies for PCOS 10 NATURAL REMEDIES FOR PCOS

blog article

Mar 08, 2019

PCOS or Polycystic ovary syndrome happens due to hormonal imbalance in women. PCOS can start as early as the teens. It is marked by excessive levels of androgens or male hormones in the body. The exact cause of PCOS still remains uncertain. Its symptoms begin to show slowly.

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9 Super Effective Ayurvedic Tips to Stay Healthy and Live Longer 9 SUPER EFFECTIVE AYURVEDIC TIPS TO STAY HEALTHY AND LIVE LONGER

blog article

Mar 08, 2019

Living a healthy and happy life needs work on your part. You can’t spend all your day playing video games or lying down in the bed and then expecting good health for life. That is unrealistic! What is realistic though is to get up early, do your yoga and make habits that contribute to a health...

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Infertility and the Leaky Pipeline INFERTILITY AND THE LEAKY PIPELINE

blog article

Mar 08, 2019

The challenges of parenthood for working parents are well known and, in STEM (Science, Technology, Math and Engineering) fields, have been strongly linked to the “leaky pipeline” the loss of women from scientific careers at much higher rates than men. In contrast, the challenges that man...

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10 Science-Backed Reasons to Eat More Protein 10 SCIENCE-BACKED REASONS TO EAT MORE PROTEIN

blog article

Mar 08, 2019

The health effects of fat and carbs are controversial. However, almost everyone agrees that protein is important. Most people eat enough protein to prevent deficiency, but some individuals would do better with much higher protein intake. Numerous studies suggest that a high-protein diet has major be...

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11 Foods That Speed Up Your Body’s Aging Process Plus Potential Swaps 11 FOODS THAT SPEED UP YOUR BODY’S AGING PROCESS PLUS POTENTIAL SWAPS

blog article

Mar 08, 2019

There are two main culprits that accelerate the aging process of our skin: sun exposure and advanced glycation end products (AGEs). AGEs form when protein or fat combine with sugar. While these aging culprits aren’t 100 percent in our control, using sunscreen and taking mind of your overall di...

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Five Reasons to Embrace Data-Driven Drug Development FIVE REASONS TO EMBRACE DATA-DRIVEN DRUG DEVELOPMENT

blog article

Mar 08, 2019

The growth of the pharmaceutical and biotechnology industry depends on successful clinical trials. The cost of developing a new drug that gets approval is estimated at around $2-3 billion. The longer the trial lasts and the more patients it has involved, the larger the loss. The researchers at Johns...

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The new standards for phenotypic screening THE NEW STANDARDS FOR PHENOTYPIC SCREENING

blog article

Mar 07, 2019

If you’ve decided you need to incorporate phenotypic screening into your discovery program and you know that one of the new generations of automation platforms is the way forward, what factors should influence your choice?

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A New Frontier in the Fight Against Cancer A NEW FRONTIER IN THE FIGHT AGAINST CANCER

blog article

Mar 07, 2019

Pathology studies the causes and effects of cancer and other diseases.  Pathologists work by examining tissue samples in a laboratory.  But with the advent of personalized medicine, the pathologist’s role is profoundly changing. Traditionally, pathologists were viewed as “...

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STUDYING HAND, FOOT, AND MOUTH DISEASE WITH HUMANIZED MICE STUDYING HAND, FOOT, AND MOUTH DISEASE WITH HUMANIZED MICE

blog article

Mar 07, 2019

Enterovirus-A71 (EV-A71), a member of the genus Enterovirus in the Picornaviridae family1, is one of the most common causes of hand, foot, and mouth disease (HFMD) in younger children and occasionally causes large-scale epidemics worldwide, especially within the Asia-Pacific region. In addition, EV-...

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Hit-to-lead discovery at a nonprofit research institute HIT-TO-LEAD DISCOVERY AT A NONPROFIT RESEARCH INSTITUTE

blog article

Mar 07, 2019

Small molecule drug discovery has long been the domain of pharmaceutical companies, and that’s not likely to change anytime soon. But there’s a cadre of universities and nonprofit research institutes that have embraced drug development at its earliest stages, in some cases identifying an...

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Genes may contribute to marital satisfaction GENES MAY CONTRIBUTE TO MARITAL SATISFACTION

blog article

Mar 07, 2019

Genes may have a discernible impact on the quality of a marriage, according to a recent study of couples in their middle and later years. Researchers at the Yale School of Public Health, New Haven, CT, investigated how a gene variant that influences the so-called love hormone oxytocin might con...

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Why do we sleep? Scientists find brain repair mechanism WHY DO WE SLEEP? SCIENTISTS FIND BRAIN REPAIR MECHANISM

blog article

Mar 07, 2019

Sleep is an important part of the daily life cycle of most animals including humans. But when an animal sleeps, it leaves itself defenseless in the face of danger. So, what makes sleeping so important that we all take this risk? Research, both old and new, acknowledges that sleep plays an impor...

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MMR vaccine does not cause autism, even in those most at risk MMR VACCINE DOES NOT CAUSE AUTISM, EVEN IN THOSE MOST AT RISK

blog article

Mar 07, 2019

A new large-scale Danish study searches for connections between autism and the MMR vaccine. In particular, they investigate at-risk individuals. Once again, no links are found. The furor surrounding vaccines and their relationship with autism have been rumbling along for decades.

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Fact or Fiction: Debunking the Latest Anti-Vax Myths FACT OR FICTION: DEBUNKING THE LATEST ANTI-VAX MYTHS

blog article

Mar 07, 2019

With more than 100 confirmed cases of measles in the United States already this year, vaccines are once again squarely at the center of passionate national debate. At the heart of the issue are the concerns of parents about the safety of vaccines for their children. These concerns are pitted against...

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Colon Cleansing Vs Ayurvedic Basti – All You Need to Know! COLON CLEANSING VS AYURVEDIC BASTI – ALL YOU NEED TO KNOW!

blog article

Mar 07, 2019

Colon cleansing is also termed as colonics or colonic irrigation. It is the procedure done to remove toxins and other waste products from your colon by administering a large amount of water or any other fluids or laxatives or by administration of purgatives orally or dietary fibers. There are variou...

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Being overweight or obese may improve stroke survival BEING OVERWEIGHT OR OBESE MAY IMPROVE STROKE SURVIVAL

blog article

Mar 06, 2019

New research reveals that being overweight, obese, or severely obese may improve a person's chances of surviving after a stroke. Obesity is a "serious medical condition" that can lead to various complications. These might include atherosclerosis and heart disease, diabetes, cancer, and...

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This sleep disorder puts people at THIS SLEEP DISORDER PUTS PEOPLE AT 'VERY HIGH RISK' OF PARKINSON'S

blog article

Mar 06, 2019

Research has linked a particular sleep disorder called rapid eye movement (REM) sleep behavior disorder with a diagnosis of Parkinson's disease. What characterizes this sleep problem, and can its presence be a good way to predict Parkinson's risk? Data from the National Institutes of He...

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Another Massive Study Finds Measles Vaccine Doesn’t Cause Autism ANOTHER MASSIVE STUDY FINDS MEASLES VACCINE DOESN’T CAUSE AUTISM

blog article

Mar 06, 2019

A large-scale study of half a million people over 10 years confirms yet again that there is no connection between the measles, mumps, rubella (MMR) vaccine, and autism. No link has been found between the measles, mumps, rubella (MMR) vaccine, and autism in largest, single study to date. Researchers ...

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Natural Language Processing in Pharma – Current Applications NATURAL LANGUAGE PROCESSING IN PHARMA – CURRENT APPLICATIONS

blog article

Mar 06, 2019

Natural language processing (NLP) seems to see less use in pharma than AI approaches such as machine vision and predictive analytics, but nevertheless there are a few applications for NLP in pharma. The industry deals mostly with structured data, but in some business areas, unstructured data is the ...

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Five ways instrument utilization data can boost your lab’s efficiency FIVE WAYS INSTRUMENT UTILIZATION DATA CAN BOOST YOUR LAB’S EFFICIENCY

blog article

Mar 05, 2019

Are you guilty of making decisions without the data to back them up? In today’s busy labs, mission-critical decisions about laboratory equipment purchases, service contract renewals, consumables spending, and staffing are often made on the basis of incomplete information. Having a clear pictur...

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What You Can Do to Help Children Adjust to Daylight Saving Time WHAT YOU CAN DO TO HELP CHILDREN ADJUST TO DAYLIGHT SAVING TIME

blog article

Mar 05, 2019

Daylight saving time can bring a welcome end to the short, dark days of winter, but it can also disrupt our natural sleep cycles. If parents fail to plan ahead, the consequence is short-term sleep deprivation for their children and teens. This can cause temporary irritability and behavioral issues i...

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Are Mosaic Embryos the "Dark Horse" of IVF? ARE MOSAIC EMBRYOS THE "DARK HORSE" OF IVF?

blog article

Mar 05, 2019

Not every embryo contains 46 perfect chromosomes. Some have more, others have fewer. The result is a common abnormality known as aneuploidy, which occurs in as many as 80 percents of human embryos. Because aneuploidy has been linked to a risk of in vitro fertilization failure, miscarriage, and certa...

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Pancreatic cancer: Two-hit treatment approach shows promise PANCREATIC CANCER: TWO-HIT TREATMENT APPROACH SHOWS PROMISE

blog article

Mar 05, 2019

It may be feasible to treat pancreatic cancer by using one drug to get the cancer cells to depend on a single source of energy, and another drug to take it away from them. The approach looks promising after a recent study successfully tested it on pancreatic cancer cells and mice in the laboratory. ...

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What are the facts of Crohn WHAT ARE THE FACTS OF CROHN'S DISEASE?

blog article

Mar 05, 2019

Crohn's disease is a lifelong condition that causes inflammation and irritation along the digestive tract. Knowing the facts about Crohn's can help a person better understand and manage their condition. In this article, we explore Crohn's disease and its causes, risk factors, and prevale...

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How does exercise impact cognitive function in Parkinson HOW DOES EXERCISE IMPACT COGNITIVE FUNCTION IN PARKINSON'S?

blog article

Mar 05, 2019

Experts have already concluded that exercise can help people with Parkinson's disease improve their motor symptoms, but what is its effect on the cognitive symptoms of this condition? Parkinson's disease is a neurological condition that usually stands out for the motor symptoms that it ...

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What to know about acute renal failure WHAT TO KNOW ABOUT ACUTE RENAL FAILURE

blog article

Mar 05, 2019

Acute renal failure is when a person's kidneys are not working as well as they once did. This usually happens very suddenly over several hours or up to 2 days. Many people do not experience symptoms until their condition has advanced. As a result of acute renal failure (ARF), the kidneys do not ...

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7 Tips for the Medication Management Process 7 TIPS FOR THE MEDICATION MANAGEMENT PROCESS

blog article

Mar 05, 2019

Medication management is the process of overseeing the medications prescribed for a patient to ensure they are taken properly and achieving their planned, therapeutic outcome. The process includes initial and ongoing medication review to address safety and adherence concerns, reduce adverse drug eve...

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Here HERE'S HOW TREATING OBESITY AND DEPRESSION AT THE SAME TIME CAN HELP

blog article

Mar 05, 2019

A new intervention helps people lose weight and improve their depression symptoms at the same time. Millions of Americans have been diagnosed with depression. Even more, have obesity. For many people, these conditions go hand in hand, increasing their risk for other health conditions and decreasing ...

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Therapeutic Approach for Pancreatic Cancer Moves Forward THERAPEUTIC APPROACH FOR PANCREATIC CANCER MOVES FORWARD

blog article

Mar 05, 2019

Even among cancers, pancreatic cancer is an especially sinister form of the disease. The one-year survival rate is extremely low, and treatment progress has lagged behind that of many other malignancies. A study published today in the journal Nature Medicine led by researchers at Huntsman Cancer Ins...

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Cocoa may help treat common MS symptom COCOA MAY HELP TREAT COMMON MS SYMPTOM

blog article

Mar 05, 2019

New research, which features in the Journal of Neurology, Neurosurgery & Psychiatry, finds that having a cocoa drink every day for 6 weeks helps combat fatigue in people living with multiple sclerosis. Multiple sclerosis (MS) is an autoimmune disorder that affects about 400,000 people in th...

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Distinctive Signature of Gut Bacteria in IBS Sufferers DISTINCTIVE SIGNATURE OF GUT BACTERIA IN IBS SUFFERERS

blog article

Mar 05, 2019

People who suffer from stress-related Irritable Bowel Syndrome have a distinctive microbial signature in their gut. However, holistic, psychosomatic therapy using hypnosis is significantly more effective at treating their condition than symptomatic or probiotic treatment alone. This is the finding o...

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'TAKING TREATMENT FOR AUTOIMMUNE DISEASE IN A NEW DIRECTION'

blog article

Mar 05, 2019

In autoimmune diseases, such as type 1 diabetes and multiple sclerosis, the body's immune system mistakenly attacks healthy cells, believing them to be harmful agents. Recently, scientists have been conducting new research with the aim of devising an innovative strategy to treat these conditions...

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Broken Heart? Look to the Brain BROKEN HEART? LOOK TO THE BRAIN

blog article

Mar 05, 2019

Scientists have shown for the first time that the brain is involved in the development of a heart condition called Takotsubo syndrome (TTS). They found that regions of the brain responsible for processing emotions and controlling the unconscious workings of the body, such as heartbeat, breathing, an...

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Exploring How Alcohol Affects Energy Use in the Brain EXPLORING HOW ALCOHOL AFFECTS ENERGY USE IN THE BRAIN

blog article

Mar 05, 2019

Assessing the patterns of energy use and neuronal activity simultaneously in the human brain improves our understanding of how alcohol affects the brain, according to new research by scientists at the National Institutes of Health. The new approach for characterizing brain energetic patterns could a...

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Renal Reabsorption in Living Devices RENAL REABSORPTION IN LIVING DEVICES

blog article

Mar 05, 2019

Every day our kidneys tackle the daunting task of continuously cleaning our blood to prevent waste, salt, and excess fluid from building up inside our bodies. To achieve this, the kidneys’ approximately one million filtration units (glomeruli) first remove both waste products and precious nutr...

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Anthelmintic drug niclosamide repurposed to treat Helicobacter pylori ANTHELMINTIC DRUG NICLOSAMIDE REPURPOSED TO TREAT HELICOBACTER PYLORI

blog article

Mar 05, 2019

Drug repurposing can often reduce the time and cost it takes to discover and develop a new drug, especially for novel antimicrobial therapies. Helicobacter pylori is a Gram-negative, helically shaped, stomach pathogen associated with human gastric mucosa. After entering the body, they can cause chro...

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Can mouthwash raise your blood pressure? CAN MOUTHWASH RAISE YOUR BLOOD PRESSURE?

blog article

Mar 05, 2019

New research, published in the journal Frontiers in Cellular and Infection Microbiology, shows that an antiseptic compound found in mouthwash destroys "friendly" oral bacteria that help maintain normal blood pressure levels. Scientists know that the bacteria in our guts influence over...

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Cancer Biologists Investigate Epigenetic Regulation of Pancreatic Cancer Cells using Live Cell Imaging CANCER BIOLOGISTS INVESTIGATE EPIGENETIC REGULATION OF PANCREATIC CANCER CELLS USING LIVE CELL IMAGING

blog article

Mar 05, 2019

A few decades ago, an important finding caused a paradigm shift in cancer genetics. Studies reported that key events in cancer initiation and progression can occur regardless of the underlying DNA. A field then emerged to curb cancer via epigenetics, the study of heritable changes in gene expression...

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Bloating: The Causes and the Cures BLOATING: THE CAUSES AND THE CURES

blog article

Mar 04, 2019

Just about all of us have experienced a bloated belly. But for some people, bloating causes near daily distress. I hear from people all the time who suffer from bloating and want to know what they should be eating or not eating to avoid it. And of course, you’ll see magazine and internet artic...

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How to treat a cold or flu at home HOW TO TREAT A COLD OR FLU AT HOME

blog article

Mar 04, 2019

Viruses are responsible for colds and flu, so antibiotics are not able to cure or prevent these illnesses. Plenty of rest, fluids, and home remedies can help relieve symptoms. Colds and the flu are common illnesses that can cause many uncomfortable symptoms, such as.

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Single injection gives mammals night vision SINGLE INJECTION GIVES MAMMALS NIGHT VISION

blog article

Mar 04, 2019

Scientists at the cutting edge of nanotechnology are on the path to the seemingly impossible: creating an injection that allows us to see in the dark. This research opens the door to brand new therapeutic interventions. The mammalian eye can only respond to a small band of wavelengths. Generally, th...

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Longer Lifespan Without a Reproduction Cost LONGER LIFESPAN WITHOUT A REPRODUCTION COST

blog article

Mar 04, 2019

Genetic manipulation that more than doubles lifespan also leads to better offspring - according to new collaborative research from the University of East Anglia and Uppsala University. Researchers studied a gene, known as DAF-2, which is associated with aging in roundworms (Caenorhabditis elegans). ...

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Embryos’ Signaling Proteins Go With the Flow EMBRYOS’ SIGNALING PROTEINS GO WITH THE FLOW

blog article

Mar 04, 2019

How cells in developing embryos communicate depend a great deal on context, according to scientists at Rice University. They found that a protein signaling pathway is known as WNT and its interactions are far more dynamic than once thought as the response of different cell types to the same signals ...

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How Your Own Plasma May Help Stop Hair Loss HOW YOUR OWN PLASMA MAY HELP STOP HAIR LOSS

blog article

Mar 04, 2019

Going bald may seem to be a fact of life for many men and women as they age, but there are new treatments that could make a difference. While there have been some longtime recommended treatments for hereditary hair loss like Rogaine and Propecia, there haven’t been any major breakthroughs in r...

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Sleeping more on weekends does not make up for past sleep loss SLEEPING MORE ON WEEKENDS DOES NOT MAKE UP FOR PAST SLEEP LOSS

blog article

Mar 04, 2019

Whenever we sleep poorly throughout the week, we comfort ourselves with the thought that we will make up for lost slumber at the weekend. However, a new study brings us the bad news: sleeping in at the weekend does not reverse the damage of chronic sleep loss.

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The Empty Promise of “Safe” Drug Importation THE EMPTY PROMISE OF “SAFE” DRUG IMPORTATION

blog article

Mar 04, 2019

For years, BIO has been urging both state and federal policymakers to adopt responsible solutions that would make prescription drugs more affordable for America’s patients. At times, our advocacy work includes the need to raise concerns with some of the policy proposals being discussed. That&r...

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Working long hours increases depression risk in women WORKING LONG HOURS INCREASES DEPRESSION RISK IN WOMEN

blog article

Mar 04, 2019

Women who clock 55 working hours or more every week might have a higher risk of depression. Also, working weekends can increase depression risk for both men and women. A new study that now appears in the Journal of Epidemiology & Community Health found that working excessively long days cou...

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Chemical Pollutants in the Home and Infertility CHEMICAL POLLUTANTS IN THE HOME AND INFERTILITY

blog article

Mar 04, 2019

New research by scientists at the University of Nottingham suggests that environmental contaminants found in the home and diet have the same adverse effects on male fertility in both humans and in domestic dogs. There has been increasing concern over declining human male fertility in recent decades ...

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The key to weight loss: THE KEY TO WEIGHT LOSS: 'LOG OFTEN, LOSE MORE'

blog article

Mar 04, 2019

Many people consider logging everything that they eat to be a tedious task. However, this effective weight-loss technique takes much less time than most people think, according to a recent study. Obesity is now a common health issue. According to the Centers for Disease Control and Prevention (CDC),...

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Artificial Intelligence & the Pharma Industry: What’s Next ARTIFICIAL INTELLIGENCE & THE PHARMA INDUSTRY: WHAT’S NEXT

blog article

Mar 04, 2019

Artificial intelligence in Pharma refers to the use of automated algorithms to perform tasks which traditionally rely on human intelligence. Over the last five years, the use of artificial intelligence in the pharma and biotech industry has redefined how scientists develop new drugs, tackle disease,...

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An Essential Guide To Effective Managed Care In Commercial Pharma AN ESSENTIAL GUIDE TO EFFECTIVE MANAGED CARE IN COMMERCIAL PHARMA

blog article

Mar 04, 2019

In response to the rapidly growing influence of managed care, the pharma industry has undergone significant transformation. In the past, to drive prescriptions, the main focus of pharma companies was selling to the individual doctors. Under the traditional fee-for-service model, physicians based the...

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Ayurveda And Its Role In Treating PCOS/PCOD AYURVEDA AND ITS ROLE IN TREATING PCOS/PCOD

blog article

Mar 03, 2019

Good health, unfortunately, is not experienced by every human being on earth. Be it a man or a woman and people of all ages do face some kind of health-related issue or contract disease at some point in time in their lives. The age of reasoning and modern science gave birth to conventional forms of ...

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Ayurvedic Treatment for Broken Capillaries (Spider Veins) AYURVEDIC TREATMENT FOR BROKEN CAPILLARIES (SPIDER VEINS)

blog article

Mar 02, 2019

Broken capillaries appear when the vein wall is too weak to withstand the pressure of the blood being pumped around the body. Reduced resistance of the vein walls is common in women during menopause, when broken capillaries in the arms and legs can mean reduced oestrogen levels (hormonal imbalance)....

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Pollutants may speed up ALS progression POLLUTANTS MAY SPEED UP ALS PROGRESSION

blog article

Mar 02, 2019

New research, appearing in the BMJ Journal of Neurology, suggests that various pollutants may not only raise the risk of people developing ALS but also make the disease advance faster. Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a neurodegenerative condition ...

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Why nutritional psychiatry is the future of mental health treatment WHY NUTRITIONAL PSYCHIATRY IS THE FUTURE OF MENTAL HEALTH TREATMENT

blog article

Mar 02, 2019

A lack of essential nutrients is known to contribute to the onset of poor mental health in people suffering from anxiety and depression, bipolar disorder, schizophrenia, and ADHD. Nutritional psychiatry is a growing discipline that focuses on the use of food and supplements to provide these essentia...

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Has fast food become worse for our health in the past 30 years? HAS FAST FOOD BECOME WORSE FOR OUR HEALTH IN THE PAST 30 YEARS?

blog article

Mar 02, 2019

Filled with empty calories and ultra-processed, fast food may increase the risk of obesity and cancer. While fast-food chains have ostensibly been trying to offer more healthful options, a new study finds that the health impact of their menus has not improved to the contrary, in fact. Data from...

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State-of-the-art assays for myasthenia gravis STATE-OF-THE-ART ASSAYS FOR MYASTHENIA GRAVIS

blog article

Mar 02, 2019

Myasthenia gravis is an autoimmune disease with an estimated prevalence of 14-20/100,000 population in the U.S. and 1-9 /100,000 population in Europe. Many affected individuals go undiagnosed. Myasthenia gravis can cause severe muscle weakness and greatly impact the quality of life. Diagnosis can be...

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How Prostate Cancer Becomes Treatment Resistant HOW PROSTATE CANCER BECOMES TREATMENT RESISTANT

blog article

Mar 01, 2019

The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant prostate cancer subtype called neuroendocrine prostate cancer (NEPC). No effective t...

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Excessive daily TV at older age tied to poorer memory EXCESSIVE DAILY TV AT OLDER AGE TIED TO POORER MEMORY

blog article

Mar 01, 2019

Older people who want to preserve their faculties may wish to consider rationing their TV time. A large new study of older adults found that those who spent at least 3.5 hours per day watching TV experienced a greater decline in verbal memory. Researchers at University College London in the Uni...

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Protein marker in response to brain cancer therapy PROTEIN MARKER IN RESPONSE TO BRAIN CANCER THERAPY

blog article

Mar 01, 2019

Brain tumors vary widely in how they respond to treatment. However, early assessment of therapy response is essential in order to choose the best possible treatment for the patient. Scientists from the German Cancer Research Center (DKFZ) have now been able to show in a study using non-invasive high...

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Colon cancer: Could exercise halt tumor growth? COLON CANCER: COULD EXERCISE HALT TUMOR GROWTH?

blog article

Mar 01, 2019

New research, appearing in the Journal of Physiology, suggests that short bursts of intense, physical activity may reduce the growth of colorectal tumor cells. According to the American Cancer Society, doctors will diagnose more than 100,000 new cases of colon cancer and in excess of 44,000 cases of...

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New compound could fight off aggressive melanoma NEW COMPOUND COULD FIGHT OFF AGGRESSIVE MELANOMA

blog article

Mar 01, 2019

New research, appearing in the journal Cell, reveals a drug compound that could halt the growth of an aggressive form of melanoma. Melanoma is a type of skin cancer that accounts for 1 percent of all skin cancer cases. Despite this small percentage, melanoma is responsible for a large number of...

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Preventing cancer: PREVENTING CANCER: 'FLAWLESS' DNA REPAIR OFFERS INSIGHT

blog article

Mar 01, 2019

A recent study dives into the details of exactly how cells fix DNA mutations. The researchers provide fresh insight into so-called flawless DNA repair. Cancer research often involves a multi-pronged approach. Of course, testing new treatments and finding novel ways to attack tumors is paramount. At ...

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Rising to the Challenge of Opioid Detection RISING TO THE CHALLENGE OF OPIOID DETECTION

blog article

Mar 01, 2019

Today, the Opioid Detection Challenge, a $1.55 million USD global prize competition, was launched by the U.S. Department of Homeland Security (DHS) Science and Technology Directorate (S&T), in collaboration with U.S. Customs and Border Protection (CBP), the Office of National Drug Control Policy...

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How to Overcome Unexplained Infertility Through Natural Remedies HOW TO OVERCOME UNEXPLAINED INFERTILITY THROUGH NATURAL REMEDIES

blog article

Mar 01, 2019

Yes! You can’t deny that infertility can be depressing and highly frustrating not only to the couple but also their families. If you have been lucky enough not to go through it, perhaps your family member or friend was. Believe me, after reading this, you will have a handful of helpful suggest...

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Quietness better than background music for creativity QUIETNESS BETTER THAN BACKGROUND MUSIC FOR CREATIVITY

blog article

Feb 28, 2019

Recent research questions the popular notion that listening to music increases creativity. Instead, it proposes that quietness, or even background library noise, is more beneficial. After conducting a series of experiments with human volunteers, researchers from the University of Gävle in ...

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The Orphan Drug Act is a Win for Patients and Innovation THE ORPHAN DRUG ACT IS A WIN FOR PATIENTS AND INNOVATION

blog article

Feb 28, 2019

Here’s a statistic that might surprise you: approximately 7,000 rare disorders are known to exist, and new ones are discovered each year. It’s not something we think about often, in fact, the media almost never cover it. However, in recognition of Rare Disease Day, it’s important t...

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Growing up in a green area may help support mental health GROWING UP IN A GREEN AREA MAY HELP SUPPORT MENTAL HEALTH

blog article

Feb 28, 2019

New research from Aarhus University in Denmark suggests that people who have grown up in close contact with nature are much less likely to develop mental health problems in adulthood than peers who had less access to green space as children. According to recent studies, mental health problems h...

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What are the main symptoms of mania? WHAT ARE THE MAIN SYMPTOMS OF MANIA?

blog article

Feb 28, 2019

The mania phase of bipolar disorder involves an unusually high level of energy and activity. It is common for people in this phase to experience racing thoughts, a lower need for sleep, and difficulty concentrating. Bipolar disorder is a condition that causes extreme changes in mood. There are diffe...

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Alcohol may be less harmful for people over 50 ALCOHOL MAY BE LESS HARMFUL FOR PEOPLE OVER 50

blog article

Feb 28, 2019

A recent study examines the health impact of consuming alcohol at different ages. The authors conclude that, for people over the age of 50, health risks may be less severe. Heavy drinking is linked to a range of serious health consequences. These include certain cancers, liver and heart disease, and...

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How to Make Cancer Drug Resistance Futile HOW TO MAKE CANCER DRUG RESISTANCE FUTILE

blog article

Feb 27, 2019

For many solid tumors, treatments undergo a cycle: the drugs initially work well, the tumor shrinks, but then becomes resistant again. Stefanie Flückiger-Mangual, CEO of the Swiss biotech Tolremo, believes that this cycle can be stopped. Solid tumors often act like a recurring villain in a TV s...

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Taking Immune Monitoring to a Whole New Level TAKING IMMUNE MONITORING TO A WHOLE NEW LEVEL

blog article

Feb 27, 2019

In 2018, there were approximately 3,400 active agents in the immuno-oncology pipeline, a 67% increase from 2017. Clinical research in the field of immunotherapies is steadily increasing, especially in the area of oncology. The growing interest in immuno-oncology therapies is also reflected in its bo...

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Spotlight on Alzheimer’s Research: Brain Awareness Week 2019 SPOTLIGHT ON ALZHEIMER’S RESEARCH: BRAIN AWARENESS WEEK 2019

blog article

Feb 27, 2019

The 11th March marks the beginning of Brian Awareness Week. As part of this campaign, the ISRCTN team have compiled a collection of recent and ongoing clinical trials into Alzheimer’s disease. Alzheimer’s disease (AD) is the most common form of dementia, a syndrome characterized by ...

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New treatment under trial could restore brain cells in Parkinson NEW TREATMENT UNDER TRIAL COULD RESTORE BRAIN CELLS IN PARKINSON'S

blog article

Feb 27, 2019

A series of clinical trials have tested an experimental treatment for Parkinson's disease that uses a novel approach: administering the drug straight into the brain via implanted ports. The leading researchers believe this may be a "breakthrough" therapeutic strategy for neurological c...

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Four things I learned from an individual with fibrous dysplasia FOUR THINGS I LEARNED FROM AN INDIVIDUAL WITH FIBROUS DYSPLASIA

blog article

Feb 27, 2019

As it does every year, Orphanet Journal of Rare Diseases is proud to partner with Findacure in its Student Voice essay contest. The overall winner will be published in the journal on Rare Disease Day, and we are proud to present the other finalists here. For this entry, undergraduate and masters stu...

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A 60-Year Study of Health and Nutrition in the U.S., Explained A 60-YEAR STUDY OF HEALTH AND NUTRITION IN THE U.S., EXPLAINED

blog article

Feb 27, 2019

By the late 1960s, the lead had been recognized as a toxic substance for over a thousand years. The heavy metal made the mind “give way,” wrote the Greek physician Dioscorides in the 1st Century AD; Vitruvius, Julius Caesar’s engineer, wrote hundreds of years later that lead aquedu...

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12 natural ways to relieve pain 12 NATURAL WAYS TO RELIEVE PAIN

blog article

Feb 27, 2019

Over-the-counter medicines such as ibuprofen and acetaminophen are effective pain relievers, but long-term use can cause side effects. Prescription medications may be addictive and have even more adverse effects. What are the best natural ways to relieve pain? People have used essential oils, herbs,...

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Functional Genomic Screening for Drug Resistance FUNCTIONAL GENOMIC SCREENING FOR DRUG RESISTANCE

blog article

Feb 27, 2019

The long process of drug discovery can take over a decade, from the identification of a target molecule, to release of a clinically approved drug that can be incorporated into therapeutic regimes. However, even after this long, convoluted, and the financially risky process is complete, treatment str...

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Ayurveda Says This Is the Key to a Healthy Immune System AYURVEDA SAYS THIS IS THE KEY TO A HEALTHY IMMUNE SYSTEM

blog article

Feb 27, 2019

In her book, The Human Advantage, neuroscientist Suzana Herculano-Houzel points to the invention of cooking as the singular advancement that led to humans developing the largest primate brain. “Cooking is essentially the act of using fire to pre-digest food, and thus to get more energy out of ...

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DECIPHERING THE COMPLEX WORLD OF HUNTINGTON’S DISEASE DECIPHERING THE COMPLEX WORLD OF HUNTINGTON’S DISEASE

blog article

Feb 27, 2019

British neurologist Edward Wild is fluent in the complicated, tongue-twisting language of Huntington’s disease. But how do you explain to people living with Huntington’s what a triplet repeat on the huntingtin gene is? And how do you interpret the findings of a huntingtin-lowering drug?

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THE BENEFITS OF VACCINATION OUTWEIGH THE RISKS THE BENEFITS OF VACCINATION OUTWEIGH THE RISKS

blog article

Feb 26, 2019

I have always made sure my children received their vaccinations on time, and wow, my daughter is off to college soon! That’s a lot of shots over the course of 18 years. Before she goes, I will occasionally spoil her with her favorite, albeit pricey, Starbucks drink: a Venti Very Berry Hibiscus...

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Governance in Healthcare: Ownership and Consistency GOVERNANCE IN HEALTHCARE: OWNERSHIP AND CONSISTENCY

blog article

Feb 26, 2019

The rise of big data, self-service, and more powerful and flexible end-user information visualization and preparation tools, consumer/ member/patient experience is impacting governance in a significant manner with regard to structure, decision rights, and accountabilities. End-users are gaining more...

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New device can detect cancer in just a drop of blood NEW DEVICE CAN DETECT CANCER IN JUST A DROP OF BLOOD

blog article

Feb 26, 2019

Some types of cancer, such as ovarian cancer, tend to remain undetected until they are too advanced for treatment to be effective. Now, an innovative tool may be able to detect cancer easily, quickly, and in minuscule amounts of blood. In a bid to find a simple, effective way of identifying har...

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Establishing Immune Memory to Rabies in the CNS ESTABLISHING IMMUNE MEMORY TO RABIES IN THE CNS

blog article

Feb 26, 2019

Researchers from Philadelphia University and Thomas Jefferson University have highlighted how building a strong immune memory response to rabies virus in the brain and spinal cord is key to protecting the CNS against infection. The rabies virus belongs to the Lyssavirus genus and transmission o...

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Osteoporosis: Some yoga poses may cause bone injuries OSTEOPOROSIS: SOME YOGA POSES MAY CAUSE BONE INJURIES

blog article

Feb 26, 2019

Although anecdotal sources and academic studies show that yoga can boost a person's well-being, some may need to use caution. A new study suggests that certain yoga poses can lead to bone injuries in people with osteoporosis or osteopenia. In the United States, about 24.5 percent of women a...

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Study ties arthritis pain reliever to heart valve disease STUDY TIES ARTHRITIS PAIN RELIEVER TO HEART VALVE DISEASE

blog article

Feb 26, 2019

A recent study has linked a common prescription drug that people with arthritis use to relieve pain and inflammation to a heart valve problem. The drug, which has the generic name celecoxib and the brand name Celebrex, belongs to a category of nonsteroidal anti-inflammatory drugs (NSAIDs) known...

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What to know about DEXA scans WHAT TO KNOW ABOUT DEXA SCANS

blog article

Feb 26, 2019

A DEXA scan usually assesses or measures bone density. It may also have used in determining body composition, such as the percentage of lean muscle and fat. The dual-energy X-ray absorptiometry (DEXA) scan uses two low-energy X-ray beams, which doctors direct toward the bones. Using dual energy leve...

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Johns Hopkins experts propose new approach to ensure success of precision medicine JOHNS HOPKINS EXPERTS PROPOSE NEW APPROACH TO ENSURE SUCCESS OF PRECISION MEDICINE

blog article

Feb 26, 2019

Precision medicine is a focus of ongoing debate. In an environment of limited research funds, there are those who believe that precision medicine should be funded because it will improve population health and those who feel that it shouldn’t because it won’t. In a viewpoint published Jan...

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What can cause back pain while breathing? WHAT CAN CAUSE BACK PAIN WHILE BREATHING?

blog article

Feb 26, 2019

If back pain occurs when a person breathes, it can signal an underlying medical condition. In some cases the pain is sharp, and possible causes range from inflammation or infection of the chest to spinal curvature and lung cancer. Back pain while breathing can also indicate a medical emergency, such...

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Women who work longer than 55 hours per week are more likely to suffer depression WOMEN WHO WORK LONGER THAN 55 HOURS PER WEEK ARE MORE LIKELY TO SUFFER DEPRESSION

blog article

Feb 26, 2019

The researchers found that women who worked for longer than 55 hours per week were more likely to exhibit symptoms of depression than women who worked the standard 35 to 40-hour week.  Men who worked longer hours were not at an increased risk of depression, although they were more susceptible t...

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The best home remedies for baby constipation THE BEST HOME REMEDIES FOR BABY CONSTIPATION

blog article

Feb 26, 2019

Babies often go a long time between bowel movements. Most of the time, it is normal for a baby to go days or even more than a week without a bowel movement. However, a baby may sometimes be constipated and need a little help. If a baby is constipated, a pediatrician may recommend using home remedies...

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Digital transformation in the pharmaceutical world DIGITAL TRANSFORMATION IN THE PHARMACEUTICAL WORLD

blog article

Feb 26, 2019

While many sectors have undergone this process by putting a data-driven approach in place, this has yet to be fully realized in pharmaceuticals. Sam Shah, director of digital development at NHS England has recently said the same is also true in the healthcare sector.

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Medicine of the future: personalizing with AI and machine learning MEDICINE OF THE FUTURE: PERSONALIZING WITH AI AND MACHINE LEARNING

blog article

Feb 26, 2019

Developing personalized and precision medicine is the next breakthrough for drug developers particularly for cancer treatments. A recent review paper, from researchers at Rutgers University Department of Biomedicine Engineering, highlights its potentially transformative impact on cancer treatments.

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'ANTIBACTERIAL' CHEMICAL IN TOOTHPASTE COULD STRENGTHEN BACTERIA

blog article

Feb 26, 2019

New research finds that triclosan, a popular antibacterial chemical, could have the opposite effect and make bacteria more rather than less resilient to antibiotic treatment. Triclosan is an antibacterial compound present in everyday household and personal-care products, such as toothpaste, soap, di...

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6 Important Reasons to Build a Commercial Pharma Data Platform 6 IMPORTANT REASONS TO BUILD A COMMERCIAL PHARMA DATA PLATFORM

blog article

Feb 25, 2019

Data is ubiquitous in the pharma industry – a commodity that weaves an intricate web of information, flowing through all aspects of your business. It’s an amazing and unforgiving stream that immediately and permanently captures everything happening within your business operations, both i...

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What to know about back pain in pregnancy WHAT TO KNOW ABOUT BACK PAIN IN PREGNANCY

blog article

Feb 25, 2019

Along with nausea, fatigue, and swollen feet, most women experience back pain at some points during pregnancy. Pregnancy-related back pain typically affects the lower back. According to one review that looked into the complaint, low-back pain affects more than two-thirds of women during pregnancy. B...

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Pulled muscle in chest: Symptoms and treatment PULLED MUSCLE IN CHEST: SYMPTOMS AND TREATMENT

blog article

Feb 25, 2019

The terms pulled the muscle and muscle strain refers to an injury that involves an overstretched or torn muscle. A person with a muscle strain in the chest may experience sudden, sharp pain in this area. Although uncomfortable, a strained chest muscle is usually a minor injury that tends to heal wit...

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What can future doctors learn from patients with rare diseases? WHAT CAN FUTURE DOCTORS LEARN FROM PATIENTS WITH RARE DISEASES?

blog article

Feb 25, 2019

As it does every year, Orphanet Journal of Rare Diseases partnered with Findacure in its Student Voice essay contest. The overall winner will be published in the journal on Rare Disease Day, and we are proud to present the other finalists here. For this entry, undergraduate and masters students from...

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The Future of Skin Care Is About the Invisible and Reversible Changes THE FUTURE OF SKIN CARE IS ABOUT THE INVISIBLE AND REVERSIBLE CHANGES

blog article

Feb 25, 2019

Advancements in technology aren’t always about doing something new. Sometimes it’s about doing something old, but better, faster, and easier. From instant, reversible nose jobs to virtual dermatology, the science of skin care is bringing new innovations to skin treatments and technology....

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Could these brain changes explain phantom limb? COULD THESE BRAIN CHANGES EXPLAIN PHANTOM LIMB?

blog article

Feb 25, 2019

New research could help to explain why some people report that they experience sensation in a missing limb, following amputation. Phantom limb is the sensation that the missing part remains attached. The vast majority of people with amputation report phantom sensations, often with pain. Now, an imag...

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Shop with a Dietitian: 5 Diabetes-Friendly Recipes and Shopping List SHOP WITH A DIETITIAN: 5 DIABETES-FRIENDLY RECIPES AND SHOPPING LIST

blog article

Feb 25, 2019

Diabetes and high blood sugar go hand in hand. The type you have type 2, type 1, or prediabetes dictates how your body reacts to sugar in the blood. Since the reaction is often dependent on what you eat, diet is one of the best ways to help regulate fluctuating blood sugar levels. The American Diabe...

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600 TRILLION SYNAPSES AND ALZHEIMERS DISEASE 600 TRILLION SYNAPSES AND ALZHEIMERS DISEASE

blog article

Feb 25, 2019

Late-onset Alzheimer’s disease is extremely difficult to model in the laboratory, one reason why no successful therapy for it exists. But scientists are using new capabilities to create more accurate, more useful research tools, bringing new hope for progress and better outcomes for patients. ...

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Insomnia tied to depression, cardiovascular disease INSOMNIA TIED TO DEPRESSION, CARDIOVASCULAR DISEASE

blog article

Feb 25, 2019

Insomnia, often blamed on stress or bad sleep habits, may instead be closely linked to depression, heart disease, and other physiological disorders, a pair of deep dives into the human genome now reveals. “Both studies are very well done,” says psychologist Philip Gehrman of the Universi...

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The Difference Between Arteries And Veins THE DIFFERENCE BETWEEN ARTERIES AND VEINS

blog article

Feb 23, 2019

Whether you have an upcoming test on the circulatory system, are looking for a deeper understanding, or just need a refresher the following video is for you. You may be confused about the difference between arteries and veins, or you may believe some common circulatory system myths.

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Sleep apnea: Daytime sleepiness might help predict cardiovascular risk SLEEP APNEA: DAYTIME SLEEPINESS MIGHT HELP PREDICT CARDIOVASCULAR RISK

blog article

Feb 23, 2019

A recent study categorizing people with obstructive sleep apnea based on their differing symptoms found a strong link between excessive daytime sleepiness and cardiovascular disease. Obstructive sleep apnea (OSA) causes sporadic airflow blockages during sleep. All of the different types of sleep apn...

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What to know about whooping cough in adults WHAT TO KNOW ABOUT WHOOPING COUGH IN ADULTS

blog article

Feb 22, 2019

Whooping cough, or pertussis, is a highly contagious condition. This infection is most common in infants, but people of all ages can contract it. Whooping cough symptoms tend to be less severe in adults than in children. Unvaccinated infants have the highest risk of developing severe symptoms and co...

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Alzheimer ALZHEIMER'S: 'HOLY HERB' EXTRACT SHOWS PROMISE AS FUTURE TREATMENT

blog article

Feb 22, 2019

Yerba santa, a plant with a long history of medicinal use in its native California, contains an active compound that could treat people with Alzheimer's disease one day. This was the conclusion that scientists at the Salk Institute for Biological Studies in La Jolla, CA came to after testing 400...

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What to know about panic attacks at night WHAT TO KNOW ABOUT PANIC ATTACKS AT NIGHT

blog article

Feb 22, 2019

A panic attack is a sudden, intense onset of distress or fear. These feelings heighten for around 10 minutes until starting to fade. Panic attacks can occur at any time of the day or night. People may experience a panic attack without warning. Others may have frequent, unexpected attacks. Those who ...

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What to know about acute respiratory failure WHAT TO KNOW ABOUT ACUTE RESPIRATORY FAILURE

blog article

Feb 22, 2019

When a person has acute respiratory failure, the usual exchange between oxygen and carbon dioxide in the lungs does not occur. As a result, enough oxygen cannot reach the heart, brain, or the rest of the body. This can cause symptoms such as shortness of breath, a bluish tint in the face and lips, a...

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How exercise can counter the effects of jet lag HOW EXERCISE CAN COUNTER THE EFFECTS OF JET LAG

blog article

Feb 22, 2019

New research in The Journal of Physiology suggests that exercising at certain times of the day can alter the circadian rhythms, potentially offering a new therapy for jet lag and shift work. Circadian rhythms, which are "physical, mental, and behavioral changes that follow a daily cycle," ...

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How language shapes our brains...and our lives HOW LANGUAGE SHAPES OUR BRAINS...AND OUR LIVES

blog article

Feb 22, 2019

Language and communication are as vital as food and water. We communicate to exchange information, build relationships, and create art. In this Spotlight feature, we look at how language manifests in the brain, and how it shapes our daily lives. We are all born within a language, so to speak, a...

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Top AI Use Cases in Pharma TOP AI USE CASES IN PHARMA

blog article

Feb 22, 2019

The DIA brings together researchers, pharma companies and innovative tech companies to addresses the challenges facing the pharma sector today. With the prevalence of AI across the business sector, it was no surprise that AI was a hot topic at two recent conferences: DIA Europe held in Vienna, and D...

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Patient Access: A Step by Step Guide PATIENT ACCESS: A STEP BY STEP GUIDE

blog article

Feb 21, 2019

In the most basic sense, patient access refers to the ability of patients and their families to take charge of their own health care. With the advent of the internet and digital marketing, medical practices and businesses have a new way to reach their target audiences. This has slowly empowered pati...

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How These 8 Medication Management Activities Can Help Patients HOW THESE 8 MEDICATION MANAGEMENT ACTIVITIES CAN HELP PATIENTS

blog article

Feb 21, 2019

Medication management is a patient-focused approach to helping patients take their medicines properly and consistently refill their prescriptions. Implementing a medication management program can improve patient outcomes, reduce unnecessary visits to the emergency room or hospital, and reduce the ne...

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Pre-treatment, group consensus peer review – preventing instead of mitigating errors PRE-TREATMENT, GROUP CONSENSUS PEER REVIEW – PREVENTING INSTEAD OF MITIGATING ERRORS

blog article

Feb 21, 2019

Peer review in publishing is common practice, but how can peer review be applied clinically in the field of radiation oncology, and what barriers need to be overcome to implement successful peer review in a clinical setting? In our recent article, we shared our experience with the use of a peer...

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Acupuncture may reduce menopause symptoms ACUPUNCTURE MAY REDUCE MENOPAUSE SYMPTOMS

blog article

Feb 21, 2019

A recent study concludes that just a relatively short course of acupuncture could significantly reduce some of the most unpleasant symptoms of menopause. Menopause typically begins in the sixth decade of life and continues for an average of 4–5 years. The symptoms of menopause can reduce overa...

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COULD A COMPUTER INVENT A DRUG? COULD A COMPUTER INVENT A DRUG?

blog article

Feb 21, 2019

David Clark, Ph.D., a Research Leader in Computer-aided Drug Design (CADD) at Charles River’s Harlow (UK) site, recently co-authored a review with Prof. Gisbert Schneider from the Swiss Federal Institute of Technology for the prestigious German chemistry journal Angewandte Chemie. The article ...

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FDA Issues Warning about Young-Blood Transfusions FDA ISSUES WARNING ABOUT YOUNG-BLOOD TRANSFUSIONS

blog article

Feb 20, 2019

The quest to rejuvenate aging people with the blood of young donors has generated paying customers, captured the popular imagination, and, now, prompted a warning from the Food and Drug Administration. The agency on Tuesday said in a statement that plasma infusions from young people provide “n...

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How Drug Company Ads Downplay Risks HOW DRUG COMPANY ADS DOWNPLAY RISKS

blog article

Feb 20, 2019

“Feeling down…feeling irritable…trouble getting up in the morning?.... Depression hurts….Drug X can help….speak to your doctor about Drug X…”.  These 60-second appeals are a ubiquitous part of the US television experience. This is because, in the U...

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Can we halt cellular aging? New drug combo shows promise CAN WE HALT CELLULAR AGING? NEW DRUG COMBO SHOWS PROMISE

blog article

Feb 20, 2019

Aging cells can become toxic to surrounding tissue, thus leading to numerous health problems. A class of drugs scientists calls senolytics could help address these health issues, and improve symptoms. Senolytics are a class of drugs that target cells that have entered senescence, meaning an old...

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What causes post-cesarean wound infections? WHAT CAUSES POST-CESAREAN WOUND INFECTIONS?

blog article

Feb 20, 2019

Post-Cesarean wound infection can occur when bacteria get into the incision wound. Doctors can treat surgical wound infections with medications and proper wound care.
An estimated 3–15 percent of woman develop an infection in their cesarean incision wounds. This article looks at the cau...

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Treating constipation in Crohn TREATING CONSTIPATION IN CROHN'S DISEASE

blog article

Feb 20, 2019

Crohn's disease tends to cause frequent diarrhea, but it can also cause constipation. This constipation may result from medications, other health conditions, or lifestyle factors. Doctors consider a person to have constipation if they have fewer than three bowel movements a week. Other symptoms ...

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Transcendental meditation can help treat PTSD TRANSCENDENTAL MEDITATION CAN HELP TREAT PTSD

blog article

Feb 20, 2019

Working with a cohort of young people with symptoms of PTSD and depression, researchers found that practicing transcendental meditation can help reduce or even reverse these symptoms. Studies have shown that meditation practices can have a significant, positive effect on mental health and how w...

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Aggressive brain cancer: Why does immunotherapy fail? AGGRESSIVE BRAIN CANCER: WHY DOES IMMUNOTHERAPY FAIL?

blog article

Feb 20, 2019

New research that now appears in the journal Nature Medicine examined glioblastoma tumors, and the results move scientists closer to understanding why this form of brain cancer does not respond as well to immunotherapy as other cancers. Immunotherapy is a treatment type that aims to boost the immune...

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Light-based production of drug discovery molecules LIGHT-BASED PRODUCTION OF DRUG DISCOVERY MOLECULES

blog article

Feb 20, 2019

Photoelectrochemical (PEC) cells are widely studied for the conversion of solar energy into chemical fuels. They use photocathodes and photoanodes to “split” water into hydrogen and oxygen respectively. PEC cells can work under mild conditions with light, which makes them also suitable f...

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Bacteria living on insects could provide new antibiotics BACTERIA LIVING ON INSECTS COULD PROVIDE NEW ANTIBIOTICS

blog article

Feb 20, 2019

Many antibiotics in use today came from bacteria that live in soil. Now, recent research reveals that bacteria that live on insects could be more effective at fighting common drug-resistant superbugs than bacteria from soil. Scientists at the University of Wisconsin-Madison have carried out the larg...

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Predictive Analytics in Pharma – Current Applications PREDICTIVE ANALYTICS IN PHARMA – CURRENT APPLICATIONS

blog article

Feb 19, 2019

It may feel as though AI applications like machine vision and natural language processing hold the most potential value to pharmaceutical companies because of their capabilities to intake and transform unstructured medical data. This is especially true with machine vision, as medical imaging data ca...

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There THERE'S MUCH WORK TO BE DONE: 8 MEDICAL ERRORS STATISTICS TO KNOW

blog article

Feb 19, 2019

Preventing medical errors must be a high priority for any healthcare provider. They are avoidable, and yet every year, medical errors greatly harm and kill patients nationwide. We know these claims to be true because of the medical errors statistics available to back them up. Here are eight medical ...

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How New Microbiome Diagnostic Technologies Can Save Lives HOW NEW MICROBIOME DIAGNOSTIC TECHNOLOGIES CAN SAVE LIVES

blog article

Feb 19, 2019

With the rise of a whole new field of research around the microbiome, what role are new technologies to identify microorganisms playing in the future of healthcare? Traditionally, microbes have been seen solely as a threat. But in the last few years, microbiome research has started to shift this vie...

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Flu breakthrough: Universal vaccine may be in sight FLU BREAKTHROUGH: UNIVERSAL VACCINE MAY BE IN SIGHT

blog article

Feb 19, 2019

Researchers have studied various flu strains and found that the body's so-called killer immune cells offer protection against all influenza viruses. Influenza A, B, and C viruses are widespread globally and infect a significant number of children and adults each year. For example, during the 201...

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Ability to do pushups may predict cardiovascular risk ABILITY TO DO PUSHUPS MAY PREDICT CARDIOVASCULAR RISK

blog article

Feb 19, 2019

A new study suggests that the more pushups a man is able to complete, the lower his cardiovascular risk and vice versa. These findings may establish a new measure of risk assessment that is simple and does not require costly specialized equipment. World Health Organization (WHO) data indicate t...

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'SMILING DEPRESSION': IT'S POSSIBLE TO BE DEPRESSED WHILE APPEARING HAPPY

blog article

Feb 19, 2019

The term “smiling depression” – appearing happy to others while internally suffering depressive symptoms has become increasingly popular. Articles on the topic have crept up in the popular literature, and the number of Google searches for the condition has increased dramatically th...

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Depression: Gene-activating drug reverses symptoms in mice DEPRESSION: GENE-ACTIVATING DRUG REVERSES SYMPTOMS IN MICE

blog article

Feb 19, 2019

New research shows that activating a gene that, in turn, boosts the activity of certain neurons involved in depression can reverse symptoms of the condition in male mice. Depression is "the leading cause of disability worldwide," as more than 300 million people across the globe are li...

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Gender transition drugs could be bad for the heart GENDER TRANSITION DRUGS COULD BE BAD FOR THE HEART

blog article

Feb 18, 2019

New research now published in the journal Circulation finds that some people who are gender transitioning may be at a higher risk of experiencing cardiovascular conditions due to the hormone therapy they are receiving. Previous studies have revealed that hormone therapy raises cardiovascular risk. F...

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Mediterranean Diet Works By Adding Up Small Improvements MEDITERRANEAN DIET WORKS BY ADDING UP SMALL IMPROVEMENTS

blog article

Feb 18, 2019

Eating a Mediterranean-type diet won’t suddenly and dramatically improve your cholesterol, magically slash your blood pressure, or help you drop 20 pounds overnight. But if you stick with it over time, it can potentially cut your risk of heart and blood vessel diseases by as much as 25%, accor...

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Bacteria keep us healthy but could they keep us young? BACTERIA KEEP US HEALTHY BUT COULD THEY KEEP US YOUNG?

blog article

Feb 18, 2019

A study in mice has indicated that the make-up of bacteria in the gut is linked with learning abilities and memory, providing a potential avenue of research into how to maintain cognitive functioning as we age. It’s part of a field of research looking at the link between gut bacteria and aging...

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Versatile Drug May Protect Baby From Hazards Of Intraamniotic Infections VERSATILE DRUG MAY PROTECT BABY FROM HAZARDS OF INTRAAMNIOTIC INFECTIONS

blog article

Feb 18, 2019

Dangerous to both mom and baby, infections or inflammations of the tissue or fluids that surround the fetus often result in preterm delivery with a high risk of serious complications for the infant. A prescription drug used to treat conditions as varied as acetaminophen overdose and cystic fibrosis,...

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Could Omega-3 Fatty Acids Help Prevent Miscarriages? COULD OMEGA-3 FATTY ACIDS HELP PREVENT MISCARRIAGES?

blog article

Feb 18, 2019

Compounds found in fish oil prevent pregnancy complications, including preterm birth, neonatal death, and stillbirth, in mice when the complications are caused by a common oral bacteria, according to research published today in the journal JCI Insight. The study, by scientists at Columbia University...

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Immunotherapy and DNA damage repair combo could target lung cancer IMMUNOTHERAPY AND DNA DAMAGE REPAIR COMBO COULD TARGET LUNG CANCER

blog article

Feb 18, 2019

Researchers have discovered that a combination of immune checkpoint blockade and targeted therapies that prevent DNA damage repair (DDR) resulted in significant tumor regression in mouse models of small cell lung cancer. Scientists have used the study results to suggest that the PARP inhibitor olapa...

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Diabetes and Alzheimer DIABETES AND ALZHEIMER'S: WHAT'S THE LINK?

blog article

Feb 17, 2019

New research has shown that impaired insulin signaling in the brain, often a feature of diabetes, may negatively impact cognition, mood, and metabolism all of which are common aspects of Alzheimer's disease. Although the conditions are seemingly independent of each other, earlier studies ha...

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Can these new compounds treat memory loss in depression? CAN THESE NEW COMPOUNDS TREAT MEMORY LOSS IN DEPRESSION?

blog article

Feb 16, 2019

Memory loss does not only occur in neurodegenerative diseases, such as dementia. It also happens with age, or in relation to mental health problems, such as depression. Now, researchers have developed new compounds that could reverse this cognitive effect. Memory loss is not solely a bedfellow of de...

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Frontal Lobe Paradox: Where People Have Brain Damage But Don FRONTAL LOBE PARADOX: WHERE PEOPLE HAVE BRAIN DAMAGE BUT DON'T KNOW IT

blog article

Feb 16, 2019

Humans have big brains and our frontal lobes, just behind the forehead, are particularly huge. Injuries to this part of the brain often happen after blows to the head or a stroke. Paradoxically, some people with frontal lobe injuries can seem unaffected until they’ve been carefully evaluated. ...

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Study finds new cognitive decline mechanism in Alzheimer STUDY FINDS NEW COGNITIVE DECLINE MECHANISM IN ALZHEIMER'S

blog article

Feb 15, 2019

People with Alzheimer's disease experience poor blood flow to the brain, which affects cognitive function. A new study conducted in a mouse model has finally uncovered the reason behind this reduced blood flow. For a while now, researchers have been aware that Alzheimer's disease goes h...

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How can estrogen help control type 2 diabetes? HOW CAN ESTROGEN HELP CONTROL TYPE 2 DIABETES?

blog article

Feb 15, 2019

New research finds that estrogen improves insulin sensitivity and details the mechanism behind this effect. The findings have a "profound impact on our understanding of obesity and diabetes, as well as potential dietary interventions," say the researchers. About 84 million people in t...

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Competition between different strains of malaria COMPETITION BETWEEN DIFFERENT STRAINS OF MALARIA

blog article

Feb 15, 2019

A recent study in Burkina Faso showed that genetic diversity in strains of malaria resulted in different degrees of disease severity and showed evidence of competition between strains. Of the five species of malaria parasites known to infect humans, Plasmodium falciparum is the most virulent, b...

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Patient Access – Pros and Cons to Improve your Healthcare Practice PATIENT ACCESS – PROS AND CONS TO IMPROVE YOUR HEALTHCARE PRACTICE

blog article

Feb 15, 2019

In the United States, we have certain expectations as consumers. We expect to shop around, read reviews, and select the best-performing and most cost-effective product. In essentially everything we want to buy, from a new television set to a vacation package, we can do this. There’s plenty of ...

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Breast pumps transmitting asthma-causing bacteria BREAST PUMPS TRANSMITTING ASTHMA-CAUSING BACTERIA

blog article

Feb 14, 2019

More often these days, mothers across the world use breast pumps to collect the milk in feeding bottle and feed their babies. A new study has revealed that these pumps may not be safe and may be contaminated with bacteria that can cause asthma in the babies later in life. The results of this study w...

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Developing a blood test for pain measurement DEVELOPING A BLOOD TEST FOR PAIN MEASUREMENT

blog article

Feb 14, 2019

Researchers have developed a blood test to measure pain. Scientists at Indiana University School of Medicine, and led by Professor Alexander Niculescu developed the breakthrough test. The team tracked hundreds of participants at the Richard L. Roudebush VA Medical Center in Indianapolis to identify ...

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Diabetes: Human Cells Can Also Change Jobs DIABETES: HUMAN CELLS CAN ALSO CHANGE JOBS

blog article

Feb 14, 2019

Biology textbooks teach us that adult cell types remain fixed in the identity they have acquired upon differentiation. By inducing non-insulin-producing human pancreatic cells to modify their function to produce insulin in a sustainable way, researchers at the University of Geneva (UNIGE), Switzerla...

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New drug shows promise against several aggressive cancers NEW DRUG SHOWS PROMISE AGAINST SEVERAL AGGRESSIVE CANCERS

blog article

Feb 13, 2019

A new phase I/II open-label, the dose-escalation trial has recently tested the effectiveness of a "Trojan horse" drug in treating multiple types of otherwise treatment-resistant cancer in its late stages. Recently, a team of experts from The Institute of Cancer Research in London and ...

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How sleep can boost your body HOW SLEEP CAN BOOST YOUR BODY'S IMMUNE RESPONSE

blog article

Feb 13, 2019

Researchers have demonstrated the importance of good-quality sleep time and time again, showing that a solid night's rest can contribute to many aspects of physical and mental well-being. One new study has explained how sleep contributes to the proper functioning of the immune system. Getti...

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PD-L1 assay specifically selects ideal patients for cancer treatment PD-L1 ASSAY SPECIFICALLY SELECTS IDEAL PATIENTS FOR CANCER TREATMENT

blog article

Feb 13, 2019

Immune checkpoint inhibitors, such as the anti-PD-1 antibody pembrolizumab, have become important tools for managing non-small-cell lung cancer (NSCLC). Assessing the level of programmed death ligand 1 (PD-L1) expressed by a tumor can help clinicians determine how the patient should be treated. A re...

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Is Stem Cell Research Revolutionizing Modern Medicine? IS STEM CELL RESEARCH REVOLUTIONIZING MODERN MEDICINE?

blog article

Feb 13, 2019

Stem cell research has been a growing area of medicine for almost 40 years. In 1981, scientists discovered ways to derive embryonic stem cells from early mouse embryos, which led researchers to discover a method for doing so from human embryos in 1998. This allowed scientists to grow the cells in la...

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How Can Healthcare Address the Problem of Opioid Pain Management? HOW CAN HEALTHCARE ADDRESS THE PROBLEM OF OPIOID PAIN MANAGEMENT?

blog article

Feb 13, 2019

Opioids claimed over 64,000 lives in 2017 and data show an almost fourfold increase in overdose deaths from 1999 to 2008.[1] Yet, opioid medications are still necessary to manage the pain following surgery or injury. So how do we balance the need for pain management with the need to reduce addiction...

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Diagnostic technique reveals biomarker differentiating bladder cancer from inflammation DIAGNOSTIC TECHNIQUE REVEALS BIOMARKER DIFFERENTIATING BLADDER CANCER FROM INFLAMMATION

blog article

Feb 12, 2019

Label-free digital pathology using infrared (IR) imaging with subsequent proteomic analysis for bladder cancer (BC) has revealed the first protein biomarker (AHNAK2) for BC. AHNAK2 differentiates between chronic cystitis (inflammation of the bladder) and a non-muscle invasive-type BC (carcinoma in s...

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Protecting vision after optic nerve trauma using arginase 2 PROTECTING VISION AFTER OPTIC NERVE TRAUMA USING ARGINASE 2

blog article

Feb 11, 2019

Researchers have shown through mouse models of tough-to-treat optic nerve trauma, that removing the enzyme arginase 2, which increases with injury, decreases neuron death in the retina as well as the degeneration of nerve fibers that connect neurons to each other and ultimately the brain. “Rig...

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Can We Stem the Tide of Unsuccessful Drugs? CAN WE STEM THE TIDE OF UNSUCCESSFUL DRUGS?

blog article

Feb 11, 2019

While an increasing number of drugs is being developed, fewer of them are approved yearly by the US Food and Drug Administration (FDA), compared to the 1990s.1 As of today, it can cost up to $ 2.6 billion for a drug to be developed over an average of 10 years.2 Pharmaceutical companies are acknowled...

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The Bliss of Chocolate An Ayurvedic Perspective THE BLISS OF CHOCOLATE AN AYURVEDIC PERSPECTIVE

blog article

Feb 11, 2019

Theobroma cacao, the food of the gods, has been used as food, medicine, and even currency for thousands of years. In its pure form, raw cacao is an amazing source of antioxidants, protecting us from free radicals, helping to keep us vibrant and healthy. Antioxidants may act to counteract the effects...

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Study analyzes evolution of Hepatitis A virus with samples from patients STUDY ANALYZES EVOLUTION OF HEPATITIS A VIRUS WITH SAMPLES FROM PATIENTS

blog article

Feb 11, 2019

Researchers of the University of Barcelona (UB) have analyzed, with massive sequencing techniques for the first time, the evolution of the Hepatitis A virus with samples from patients. The results, published in the journal EBioMedicine, show the presence of variants of the virus that could escape th...

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5 Use Cases for Commercial Pharma AI Beyond Drug Discovery 5 USE CASES FOR COMMERCIAL PHARMA AI BEYOND DRUG DISCOVERY

blog article

Feb 11, 2019

Artificial Intelligence, or AI for short, has been one of those buzzwords that’s been circulating throughout the healthcare industry. Most recently, it has been widely considered to be extremely beneficial for drug discovery and in clinical trials. However, that’s just a very small aspec...

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7 startling facts that will make you quit alcohol today 7 STARTLING FACTS THAT WILL MAKE YOU QUIT ALCOHOL TODAY

blog article

Feb 08, 2019

Since the dawn of civilization, man has found great fascination in concocting fermented beverages. Be it from grains or from ripe fruits alcohol-making appears in the earliest recorded documents, dating back to 7000 B.C. There are numerous reasons as to how this culture of alcohol consumption stood ...

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Protection against Mayaro virus using engineered DNA vaccine PROTECTION AGAINST MAYARO VIRUS USING ENGINEERED DNA VACCINE

blog article

Feb 08, 2019

A novel, synthetic DNA vaccine developed at The Wistar Institute induces protective immunity against Mayaro virus (MAYV), a mosquito-borne infection endemic to South America, that has the potential to become a global emerging viral threat. Since its discovery in 1954, MAYV infections have been confi...

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5 menstruation myths you must leave behind 5 MENSTRUATION MYTHS YOU MUST LEAVE BEHIND

blog article

Feb 08, 2019

Approximately half of the world's population experiences will experience, or has experienced menstruation, and yet myths about this biological process still abound. In this Spotlight feature, we debunk some of the most widespread menstruation misconceptions. As of 2017, the world's popu...

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Anti-CRISPR Proteins Could Improve Gene Editing Precision ANTI-CRISPR PROTEINS COULD IMPROVE GENE EDITING PRECISION

blog article

Feb 08, 2019

A research group in Denmark has found proteins in gut and soil microbes that can inhibit the action of CRISPR-Cas9 gene editing, a finding that could help to control the technology with more precision and less risk. Bacteria and viruses have fought an evolutionary arms race for millions of years. Ba...

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WILL A HAUNTING RARE DISEASE FINALLY MEET ITS MATCH? WILL A HAUNTING RARE DISEASE FINALLY MEET ITS MATCH?

blog article

Feb 07, 2019

Given the complexity and size of the human genome, it’s hard to imagine that a glitch in a single gene can lead to so much devastation. Yet that’s the reality of Sanfilippo syndrome, or “MPS type III” an inherited disease that strikes about 5 in a million – sadly, most ...

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DOES YOUR DRUG HAVE AN EFFECT ON HEMOSTASIS? DOES YOUR DRUG HAVE AN EFFECT ON HEMOSTASIS?

blog article

Feb 07, 2019

Pretty much every drug comes with some side-effect. One of the most dangerous side-effects is when the drug alters hemostasis by affecting coagulation factors and/or platelets. Normally, hemostasis keeps blood within damaged vessels after an injury. Few drugs are developed specifically to modify hem...

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Virtual drug discovery tackles unknown universe of drugs VIRTUAL DRUG DISCOVERY TACKLES UNKNOWN UNIVERSE OF DRUGS

blog article

Feb 07, 2019

Researchers have developed the world’s largest virtual pharmacology platform and have shown that it is capable of identifying extremely powerful drugs. The researchers mentioned that the platform, soon to contain over a billion virtual molecules never before synthesized and not found in nature...

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Ob–Gyns Do Too Much Fetal Monitoring OB–GYNS DO TOO MUCH FETAL MONITORING

blog article

Feb 07, 2019

For nearly three decades, I reminded every woman I saw in my family practice, from adolescence onward, to do a monthly self-breast examination (SBE). It made great sense in theory: the earlier you find a malignancy, the earlier you can treat it, and the better the outcome. But when researchers looke...

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6 Ways Clinicians Can Improve Medication Management for Seniors 6 WAYS CLINICIANS CAN IMPROVE MEDICATION MANAGEMENT FOR SENIORS

blog article

Feb 07, 2019

As people age, their risk of medication-related problems increases. As a Consumer Reports article notes, "When it comes to risks from prescription drugs, seniors face triple jeopardy." Older adults are more likely to take multiple medications. In fact, roughly half of adults 65 and ol...

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See-Through Fish Aid Scientists In Autism-Related Breakthrough SEE-THROUGH FISH AID SCIENTISTS IN AUTISM-RELATED BREAKTHROUGH

blog article

Feb 06, 2019

University of Miami researchers has discovered a clue in the humble zebrafish’s digestive tract that, one day, could help people on the autism spectrum alleviate one of the most common yet least studied symptoms of their disorder: gastrointestinal distress. By replicating a mutation in ze...

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Treatment could prevents and treat Chlamydia TREATMENT COULD PREVENTS AND TREAT CHLAMYDIA

blog article

Feb 06, 2019

Scientists have developed a method of treating and preventing Chlamydia one of the most common sexually transmitted bacterial infections all over the world. Researchers at the University of Waterloo mentioned how this treatment differed from the traditional antibiotic treatment as it leans towards b...

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Overdose Deaths Could Increase With ‘Changing Nature’ Of Opioid Epidemic OVERDOSE DEATHS COULD INCREASE WITH ‘CHANGING NATURE’ OF OPIOID EPIDEMIC

blog article

Feb 06, 2019

The opioid epidemic in the United States could be responsible for 700,000 overdose deaths between 2016 and 2025, according to a new study published today in JAMA Network Open. “Preventing people from misusing prescription opioids is important and could help prevent some overdose deaths in the ...

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How to Get Fit Using Electrical Muscle Stimulation (EMS) HOW TO GET FIT USING ELECTRICAL MUSCLE STIMULATION (EMS)

blog article

Feb 06, 2019

Electrical Muscle Stimulation (EMS), also known as neuromuscular electrical stimulation (NMES) or electromyo stimulation, is a protocol that elicits a muscle contraction using electrical impulses that directly stimulate your motor neurons. An EMS unit (like a Powerdot, Complex, Tone-A-Matic, or Marc...

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NSAID Pretreatment Impairs Immune Response In Heart Failure, Worsens Heart And Kidney Damage NSAID PRETREATMENT IMPAIRS IMMUNE RESPONSE IN HEART FAILURE, WORSENS HEART AND KIDNEY DAMAGE

blog article

Feb 06, 2019

Non-steroidal anti-inflammatory drugs, or NSAIDs, are widely known as pain-killers and can relieve pain and inflammation. However, prolonged use raises the risk of heart and kidney failure events. A heart attack causes the death of heart muscle cells by lack of oxygen, and it also significantly inju...

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Fibromyalgia: Many may receive the wrong diagnosis FIBROMYALGIA: MANY MAY RECEIVE THE WRONG DIAGNOSIS

blog article

Feb 06, 2019

Fibromyalgia is a chronic condition that affects millions of people in the United States. However, the authors of a new study now warn that a significant number of people who have received a diagnosis may not, in reality, have this condition. People with fibromyalgia experience pain all over th...

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Immunosuppressants reduce artery plaque in people with psoriasis IMMUNOSUPPRESSANTS REDUCE ARTERY PLAQUE IN PEOPLE WITH PSORIASIS

blog article

Feb 06, 2019

New research finds that treatment with biologic drugs reduces coronary plaque buildup among people with severe psoriasis. Psoriasis is a chronic, inflammatory skin condition that affects 7.5 million people in the United States and approximately 125 million worldwide. Psoriasis is also the most ...

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10 Minutes in One Shot. That’s How Quickly You Can Screen 664 Forensics Compounds 10 MINUTES IN ONE SHOT. THAT’S HOW QUICKLY YOU CAN SCREEN 664 FORENSICS COMPOUNDS

blog article

Feb 06, 2019

Drug testing is a moving target. As novel psychoactive substances (NPS) rapidly emerge as a new class of designer stimulants (DS), global use has reached an all-time high over the last decade. Supposedly ‘legal’ alternatives to internationally controlled drugs, these compounds are typica...

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A diet rich in fiber and vegetables can relieve depression A DIET RICH IN FIBER AND VEGETABLES CAN RELIEVE DEPRESSION

blog article

Feb 05, 2019

A healthful diet can "significantly reduce" symptoms of depression. That's the definitive conclusion from a meta-analysis of existing randomized, clinical trials. Researchers have long suspected that a poor diet can lead to poor mental health. Although the underpinnings of mental ...

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Rumors of Age Reversal: The Plasma Fraction Cure RUMORS OF AGE REVERSAL: THE PLASMA FRACTION CURE

blog article

Feb 05, 2019

I say “rumors” because there is no publication and results from just 6 rats, all of which were sacrificed for the sake of tissue biopsies.  Worse, we have no announcement of what the active agent(s) were that rejuvenated the rats, so discussion of mechanisms will have to wait. I&rsq...

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Sleep apnea may stop you from forming life memories SLEEP APNEA MAY STOP YOU FROM FORMING LIFE MEMORIES

blog article

Feb 05, 2019

New research suggests that obstructive sleep apnea may impair a person's ability to form meaningful memories about their personal life. Such dysfunction may, in turn, be a sign of depression, caution the researchers. Obstructive sleep apnea (OSA) is a sleep disorder that affects more than 1...

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Flaxseed fiber could help reduce obesity FLAXSEED FIBER COULD HELP REDUCE OBESITY

blog article

Feb 05, 2019

Flaxseed has many culinary uses, most commonly in granola and smoothies. It is a popular add-on in foods because research has suggested that it has many health benefits, including improving cholesterol. Now, a new study in an animal model shows how flaxseed can impact obesity markers. Flaxseeds...

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5 Qualities of Medication Management Systems for Providers 5 QUALITIES OF MEDICATION MANAGEMENT SYSTEMS FOR PROVIDERS

blog article

Feb 05, 2019

Effective medication management is vital to achieving optimal outcomes. When providers can help their patients adhere to a medication regimen, risks such as adverse drug reactions, unnecessary admissions, illness, and even death are reduced and clinical goals are more likely to be achieved. Consider...

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Antitumor protein can sometimes promote cancer ANTITUMOR PROTEIN CAN SOMETIMES PROMOTE CANCER

blog article

Feb 04, 2019

A protein that plays a key role in protecting the body against cancer also appears to have the opposite effect in some cancers. New research from the University of California in San Diego demonstrates instances in which the tumor suppressor protein p53 can boost cancer metabolism. In a paper on the ...

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Fasting boosts metabolism and fights aging FASTING BOOSTS METABOLISM AND FIGHTS AGING

blog article

Feb 04, 2019

The latest study to explore the impact of fasting on the human body concludes that it increases metabolic activity more than previously realized and may even impart anti-aging benefits. Studies have shown that intermittent fasting can help certain people lose weight. Although researchers are still d...

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Hypertension: Home-based care may be the future HYPERTENSION: HOME-BASED CARE MAY BE THE FUTURE

blog article

Feb 04, 2019

Innovators and clinicians have developed and tested a new home-based care-delivery program. The new system helped 81 percent of study participants successfully control their blood pressure. Blood pressure is the force of blood pushing against the artery walls. Blood pressure rises and falls througho...

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‘Enhanced Recovery’ Protocol Reduces Opioid Use In Spinal Surgery Patients ‘ENHANCED RECOVERY’ PROTOCOL REDUCES OPIOID USE IN SPINAL SURGERY PATIENTS

blog article

Feb 04, 2019

A novel “Enhanced Recovery After Surgery” (ERAS) protocol developed by Penn Medicine for patients undergoing spinal and peripheral nerve surgery significantly reduced opioid use. A new study published in the Journal of Neurosurgery: Spine showed that when an ERAS protocol was employed wh...

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Research Could Lead To Treatments For Muscle Wasting In Cancer Patients RESEARCH COULD LEAD TO TREATMENTS FOR MUSCLE WASTING IN CANCER PATIENTS

blog article

Feb 04, 2019

Researchers have found that evidence of cachexia, or muscle loss in cancer patients that can be life-threatening, emerges early in tumor development, a discovery that broadens understanding of the complicated effects of cancer on the body and advances their study of the condition to find ways to tre...

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Clusterin linked to both cardiac and metabolic diseases CLUSTERIN LINKED TO BOTH CARDIAC AND METABOLIC DISEASES

blog article

Feb 04, 2019

Scientists have linked the protein clusterin to a number of different cardiometabolic syndrome risks, by identifying its actions in the liver. Researchers at The Ohio State University College of Medicine, Houston Methodist Research Institute and Houston Methodist Cancer Center spent nearly a decade ...

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Combination therapy may halt the progression of neuroblastoma in children COMBINATION THERAPY MAY HALT THE PROGRESSION OF NEUROBLASTOMA IN CHILDREN

blog article

Feb 04, 2019

The MYCN oncogene has long been known to be a key cause of a number of deadly solid tumor cancers, including neuroblastoma, which claims more lives of children under the age of 5 than any other cancer. Neuroblastoma is the most common solid tumor found in young children. In up to 25 percent of cases...

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Are we facing a Parkinson ARE WE FACING A PARKINSON'S PANDEMIC?

blog article

Feb 03, 2019

According to one new study paper, the evidence is emerging that Parkinson's disease is becoming a pandemic. The authors discuss their concerns and the challenges ahead. Parkinson's disease is a neurodegenerative condition. Primarily affecting the motor regions of the central nervous system, ...

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Does Intermittent Fasting Work? DOES INTERMITTENT FASTING WORK?

blog article

Feb 02, 2019

One of the biggest diet and nutrition trends these days is intermittent fasting. Every week, I hear from listeners wanting to know my thoughts on it. I've mentioned intermittent fasting on the podcast before, in an episode on the health benefits of fasting. But that was way back in 2011. At that...

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Investigating Immunologic Approaches to Cancer Treatment INVESTIGATING IMMUNOLOGIC APPROACHES TO CANCER TREATMENT

blog article

Feb 01, 2019

At NewYork-Presbyterian Hospital and its affiliated medical schools, Columbia University College of Physicians and Surgeons and Weill Cornell Medical College, innovators in science and medicine are pursuing cancer research with the potential to redefine the field. There is an urgency in their work t...

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How can the development of brain stem cells into neurons cause cancer? HOW CAN THE DEVELOPMENT OF BRAIN STEM CELLS INTO NEURONS CAUSE CANCER?

blog article

Feb 01, 2019

Scientists have identified how brain stem cells could cause brain cancer instead of developing into neurons. Researchers at the German Cancer Research Center (DKFZ) followed stem cells along the path of development towards becoming neurons. The team analyzed each step where genes were switched on an...

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Flu-like illness raises the risk of stroke FLU-LIKE ILLNESS RAISES THE RISK OF STROKE

blog article

Feb 01, 2019

Two new research studies show that the chance of experiencing a stroke is significantly higher after flu or flu-like illness. Each year, nearly 800,000 people in the United States experience a stroke. The risk factors include weight, smoking status, age, and family history of stroke. However, flu an...

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Medical cannabis relieves symptoms in children with autism MEDICAL CANNABIS RELIEVES SYMPTOMS IN CHILDREN WITH AUTISM

blog article

Feb 01, 2019

In a new study of patients with autism who are 18 years old and under, researchers from Ben-Gurion University of the Negev (BGU) and Soroka University Medical Center report that cannabis as a treatment for autism spectrum disorders appears to be a well-tolerated, safe and effective option to relieve...

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Certain E-cigarette Flavoring Chemicals Could Impair Lung Function CERTAIN E-CIGARETTE FLAVORING CHEMICALS COULD IMPAIR LUNG FUNCTION

blog article

Feb 01, 2019

Electronic cigarettes or “e-cigarettes” are devices that vaporize a liquid solution which can then be inhaled by the user, delivering a dose of nicotine. E-cigarettes have gained significant popularity as an alternative to conventional cigarettes, which is reflected by the vast number of...

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Females Find Social Interactions To Be More Rewarding Than Males FEMALES FIND SOCIAL INTERACTIONS TO BE MORE REWARDING THAN MALES

blog article

Feb 01, 2019

Females find same-sex social interactions to be more rewarding than males, and females are more sensitive to the rewarding actions of oxytocin (OT) than males, according to a research study that used Syrian hamsters to investigate the brain mechanisms that determine the rewarding properties of socia...

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Pinpointing the Cells That Control the Brain’s Memory Flow PINPOINTING THE CELLS THAT CONTROL THE BRAIN’S MEMORY FLOW

blog article

Feb 01, 2019

From the cab driver heading for Times Square to the commuter returning home on the freeway, we all carry maps in our head labeled with important locations. And a new Columbia study in mice shows that, by directing the delicate ebb-and-flow of brain activity, a small cluster of cells helps the brain&...

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Albendazole for lymphatic filariasis… direct hit or misfire? ALBENDAZOLE FOR LYMPHATIC FILARIASIS… DIRECT HIT OR MISFIRE?

blog article

Feb 01, 2019

For two decades albendazole has been donated for lymphatic filariasis mass treatment programs. An updated Cochrane Review investigates the effectiveness of albendazole for lymphatic filariasis. Lymphatic filariasis, a disease common in tropical and subtropical areas, is spread by mosquitoes and...

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Can We Treat Mood Disorders With Pharmacological Therapeutics? CAN WE TREAT MOOD DISORDERS WITH PHARMACOLOGICAL THERAPEUTICS?

blog article

Feb 01, 2019

Clinical treatments for neurological and mood disorders like anxiety disorder (SAD) and major depressive disorder (MDD) have failed to show consistent efficacy in treating patients. VistaGen Therapeutics is aiming to correct that. VistaGen’s compound AV-101, an NMDA receptor antagonist, is cur...

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10 Ways Machine Learning and AI Revolutionizes Medicine and Pharma 10 WAYS MACHINE LEARNING AND AI REVOLUTIONIZES MEDICINE AND PHARMA

blog article

Feb 01, 2019

According to McKinsey, machine learning and artificial intelligence in pharma and medicine are going to revolutionize the industries to help them make better decisions, optimize innovations, improve the efficiency of clinical and research trials, and provide for new tools for physicians, consumers, ...

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Fathers Are Happier Parents Than Mothers, New Study Shows FATHERS ARE HAPPIER PARENTS THAN MOTHERS, NEW STUDY SHOWS

blog article

Jan 31, 2019

A study of 18,000 people shows that fathers experience more well-being from parenthood than mothers. Past studies have considered whether people with children have greater well-being than people without children. They do. But few have considered the relative happiness of fathers and mothers.

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