IMPROVING T CELL FUNCTION IN THE SOLID TUMOR MICROENVIRONMENT

March 9, 2019

In recent years, cancer immunotherapies, in particular, immune checkpoint blockade and combination therapies, have demonstrated remarkable success in treating multiple refractory cancers. One such therapeutic approach prevents T cell exhaustion by blocking the PD-1/PD-L1 pathway, which has shown tumor regression and long-term patient survival in many clinical trials. Yet, despite the excitement surrounding these successes, a significant number of patients with advanced melanoma experience disease progression despite treatment.

Spotlight

Meda

Meda is a leading international specialty pharma company with a broad product portfolio reaching more than 80% of the global pharmaceutical market. Sales at the end of 2015 amounted to SEK 19,6 billion. Meda has its own operations in close to 60 countries and our products are sold in more than 150 countries. At the end of 2015 Meda had around 4,600 employees, 2,690 of which worked in sales and marketing.

OTHER WHITEPAPERS
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MOLECULAR GLUES LANDSCAPE IN DRUG DISCOVERY

whitePaper | June 21, 2022

nduced-proximity targeted protein degradation (TPD) is a ground-breaking strategy in drug discovery that has emerged during the last decade.

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The convergence of the pharmaceutical and medicaldevices industries

whitePaper | May 26, 2022

The medical device and pharmaceutical industries each share in a mission to improve health outcomes, from prevention to intervention. As a result of this shared mission, integration and overlap between these two industries has been taking place for decades.

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Ultimate Pharma Messaging Guidebook

whitePaper | March 10, 2023

This pharma messaging guidebook features 20 proven cognitive science techniques that can be used to optimize pharmaceutical claims and messages.

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Choosing the Right Temperature Monitoring Solution

whitePaper | April 24, 2023

Globally, pharmaceutical regulators are becoming attuned to cold chain issues as biologics, vaccines, and other temperature‐sensitive products are commercialized for a global clientele. Many regulators now recommend including temperature monitoring technology in every cold chain shipment.

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A Vision for the Global Generic and Biosimilar Medicines Industry

whitePaper | May 22, 2021

One of the key roles of the generic and biosimilar medicines industry is specifically to promote the widest possible access to affordable medicines with high quality, safety, and efficacy for patients globally by introducing competition into the markets. Despite the many hurdles, the generic medicines companies have clearly lived up to the challenges posed by the pandemic as it is an industry that is quick to adapt and agile in manufacturing scale-up. During the outbreak of COVID-19, this industry was providing most of the medicines needed in Intensive Care Units to ventilate critically ill COVID patients. It is also providing most of the quality medicines dispensed around the world, especially for increasingly prevalent chronic diseases and is therefore a strong contributor to health outcomes globally.

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Determine the right dust collection equipment for tablet press applications

whitePaper | October 13, 2022

Though tablet compression does not generate large volumes of fugitive dust, safe and efficient collection of whatever dust is created by this process is critical. The dust collector linked to the press can contribute to reliable, consistent performance

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Spotlight

Meda

Meda is a leading international specialty pharma company with a broad product portfolio reaching more than 80% of the global pharmaceutical market. Sales at the end of 2015 amounted to SEK 19,6 billion. Meda has its own operations in close to 60 countries and our products are sold in more than 150 countries. At the end of 2015 Meda had around 4,600 employees, 2,690 of which worked in sales and marketing.

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