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Epigenetic Drugs in Oncology: Current Clinical Landscape and Emerging Trends

Epigenetics is the study of heritable, reversible forms of gene regulation that are not dependent on the DNA sequence. This regulation includes DNA methylation and histone methylation, acetylation, ubiquitination, and phosphorylation. 1 While epigenetic modifications are crucial for normal functioning in all stages in life, from embryonic development through adulthood, these events are also associated with many cardiovascular, metabolic and neurological diseases as well as cancer.

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ZOLL Medical Corporation

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Epigenetic Drugs in Oncology: Current Clinical Landscape and Emerging Trends